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All Journal International Journal of Integrated Health Sciences Majalah Kedokteran Bandung Althea Medical Journal Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry ATIKAN Jurnal SIKAP (Sistem Informasi, Keuangan, Auditing Dan Perpajakan) Indonesian Journal of Rheumatology Indonesian Journal of Cardiology Heart Science Journal Jurnal Bakti Masyarakat Manajemen Jurnal Pengabdian Sosial
Syarief Hidayat
Departemen Kardiovaskular Fakultas Kedokteran Universitas Padjadjaran/Rumah Sakit Dr. Hasan Sadikin Bandung
Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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Journal : Heart Science Journal

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Right ventricular function preservation in conduction system pacing (CSP): Impact of lead-to tricuspid annulus distance left bundle branch area pacing (LBBAP) vs. his-bundle pacing (HBP) Mirza, Try Ahmad; Pranata, Raymond; Kamarullah, William; Iqbal, Mohammad; Hidayat, Syarief; Achmad, Chaerul; Karwiky, Giky
Heart Science Journal Vol. 7 No. 1 (2026): Accelerating Clinical Breakthroughs: The Journey from Molecular Discovery to Pa
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2026.007.01.15

Abstract

Background: Pacemaker remains the most effective therapy for the management of conduction disorders; however, traditional methods of right ventricular (RV) pacing have given way to more advanced conduction system pacing (CSP) techniques, such as His Bundle Pacing (HBP) and Left Bundle Branch Area Pacing (LBBAP). Objective: The impact of these two techniques on RV function is the objective of this study. Methods: This longitudinal prospective cohort study investigates differences in RV function among patients who have undergone HBP and those who have received LBBAP, using the echocardiographic parameters: fractional area change (FAC), RV global longitudinal strain (RVGLS), tricuspid annular plane systolic excursion (TAPSE), and the progression of tricuspid regurgitation (TR), with a focus on lead placement distance to the tricuspid annulus (TA) within LBBAP subgroup. Result: Among the 64 patients (33 in the HBP group and 31 in the LBBAP group), LBBAP patients with a lead-to-TA distance > 21.5 mm showed significantly better preservation of RV function across all metrics compared to HBP, specifically noted in TAPSE (1.83±5.34 vs. -1.06±3.77 in HBP, p=0.048), FAC (7.83±9.98 vs. 2.42±10.63 in HBP, p=0.011), and also RVGLS improvement (p=0.020). Conclusion: LBBAP with lead placement > 21.5 mm from the TA better preserves RV function compared to HBP mainly by minimizing mechanical interference with the tricuspid valve and reducing TR risk.
Co-Authors - Erwinanto, - Achmad Fauzi Yahya, Achmad Fauzi Achmad Shidiq, Achmad Ahmad Rizal Ganiem Akbar, Mohammad Rizki Amelia, Cindy Putri Amilia Nabhila Anak Agung Gede Sugianthara Ani Melani Maskoen Anugrah Aulia Ulil Amri, Anugrah Aulia Ulil Arlette Suzy Puspa Pertiwi Aryani, Dwi Destaria Augustine Purnomowati Aulia, Disya Jasmine Aulia, Mohammad Sidqi Badai Bhatara Tiksnadi Chaerul Achmad Cindy Putri Amelia Decruz, Ashley Ann Decruz, Ashley Ann Dewi, Triwedya Indra Dian Anggraeni Dini Rostiati, Dini Dwiyanti, Tsabitah Mariyah Eka Chemiawan Eriska Riyanti Gildasya Gildasya Hadiana, Hadiana Hutabarat, Debora Inne Suherna Sasmita Irham Rasyid Ismail, Muhammad Taofik Jakobus Runkat, Jakobus Januar Wibawa Martha Januarsih Iwan Rachman, Januarsih Iwan Julius B. Dewanto, Julius B. Jungjunan, Ridho Kamarullah, William Karwiky, Giky Kusumawardhani, Nuraini Yasmin Laniyati Hamijoyo Lestari, Tria Mahisa, Delvia Shafa Meirina Gartika Miryasandra, Astari Mirza, Try Ahmad Mohammad Iqbal Muhammad Rizki Akbar, Muhammad Rizki Mungkas, Ihfa Nabhila, Amilia Olivia Olivia Pintoko Tedjokusumo, Pintoko Pranata, Raymond Putri, Fadillah Amanda Raharjo, Pradana Pratomo Rahyono Rahyono Rama Nusjirwan Ramadhani, Revanti Ramadhani, Revanti Rezkita, Aliya Rahmadewi Risti Saptarini Primarti Roosje Rosita Oewen, Roosje Rosita Ruseka, Fahmi Damarjati Sativa, Liariza Sheila Sumargo, Sheila Toni Mustahsani Aprami, Toni Mustahsani Vani, Wulan Septio Wuri Handayani Wuryanti, Lestari Yahya­, Achmad Fauzi Yetty Herdiyati Yetty Herdiyati, Yetty