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All Journal International Journal of Integrated Health Sciences Majalah Kedokteran Bandung Althea Medical Journal Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry ATIKAN Jurnal SIKAP (Sistem Informasi, Keuangan, Auditing Dan Perpajakan) Indonesian Journal of Rheumatology Indonesian Journal of Cardiology Heart Science Journal Jurnal Bakti Masyarakat Manajemen Jurnal Pengabdian Sosial
Syarief Hidayat
Departemen Kardiovaskular Fakultas Kedokteran Universitas Padjadjaran/Rumah Sakit Dr. Hasan Sadikin Bandung
Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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Journal : Althea Medical Journal

 1 
Relation between Preinfarction Angina and Coronary Collateral Circulation in Patients with Acute Myocardial Infarction Shidiq, Achmad; Hidayat, Syarief; Rachman, Januarsih Iwan
Althea Medical Journal Vol 3, No 1 (2016)
Publisher : Althea Medical Journal

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Abstract

Background: Coronary collateral circulation conduits an alternative blood flow to the ischemic myocardium in the setting of coronary artery occlusion which can prevent the infarction area to extend more widely. Well-developed coronary collaterals are closely related with the presence of preinfarction angina. However, the duration of preinfarction angina which can induce well-developed coronary collateralization is in controversy. The aim of this study was to evaluate the relation between duration of preinfarction angina and coronary collaterals circulation in patients with acute myocardial infarction.Methods: This cross-sectional study was conducted from May to November 2013 in Dr. Hasan Sadikin General Hospital, Bandung, Indonesia. Seventy three acute myocardial infarction (AMI) patients were included in the study. The patients were divided into Group 1 (<7 days) and Group 2 (≥7 days) based on their preinfarction angina history. The coronary collaterals were assesed and graded as good (Rentrop score 2−3) and poor (Rentrop score 0−1).Statistical analysis was performed using the chi-square test.Result: The presence of a well-developed coronary collateral was not significantly different in <7days than ≥7 days duration of preinfarction angina [50.8% v 75.0%, p=0.124].Conclusions: There is no relation between the duration of preinfarction angina and coronary collaterals circulation in patients with acute myocardial infarction. [AMJ.2016;3(1):28–33]DOI: 10.15850/amj.v3n1.709
Coronary Risk Factors and Collateral Circulation in Acute Myocardial Infarction Sumargo, Sheila; Dewanto, Julius B.; Hidayat, Syarief
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

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Background: Coronary arterial stenosis, the major cause of acute myocardial infarction (AMI), induces shear stress to surrounding arteriolar endothelium. This stimulates changes in endothelial cells, smooth muscle cells and fibroblast to create collaterals that can provide alternative blood flow to the jeopardized myocardial area. However, coronary collateralization is various among AMI patients. The aim of this study was to analyze the correlation between coronary risk factors and collateral sirculation in AMI patients.Methods: A retrospective cross-sectional study was carried out to 148 medical records of hospitalized AMI patients in Dr. Hasan Sadikin General Hospital Bandung, Indonesia. All patients were assessed for coronary collateral circulation which were graded as good (Rentrop score 2–3) and poor (Rentrop score 0–1). Risk factors noted in this study were age group, sex, hypertension, diabetes mellitus and diagnosis (ST-segment Elevation Myocardial Infarction (STEMI) or Non STEMI (NSTEMI)) according to the medical record data. Results: Hypertension was found to be associated with the presence of good coronary collateral circulation (p=0.02, PR=1.410 [95% CI 1.030-1.930]). Sex, age group, diabetes mellitus and STEMI or NSTEMI diagnosis were not statistically significant.Conclusions: Hypertension was the only coronary risk factor associated to the presence of well-developed coronary collaterals. The increase of myocardial oxygen demand and flow of collateral feeding coronary artery in the setting of hypertension may contribute to the results.  DOI: 10.15850/amj.v2n4.688
Durian Consumption Effect on the Plasma Malondialdehyde Level as Biomarker of Stress Oxidative in Rats Amri, Anugrah Aulia Ulil; Maskoen, Ani Melani; Hidayat, Syarief
Althea Medical Journal Vol 3, No 1 (2016)
Publisher : Althea Medical Journal

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Background: Excessive consumption of durian (Durio zibethinus Murray) in Indonesia is often connected with its effect on health. This study aims to understand the effect of durian consumption to malondialdehyde (MDA) in plasma as oxidative stress biomarker.Methods: The study used an experimental research design on animal models, in the Biochemistry and Molecular Biology Department, Faculty of Medicine, Universitas Indonesia, July–August 2012. Thirty two Sprague-Dawley rats were used, divided into four groups: control, treatment week 1, 2, and 3. Each treatment group was given 20 gram durian fruit diluted with water until 20 ml volume per oral, divided into two doses (10 ml each) with 4 hours interlude between doses for 1 week, 2 weeks, and 3 weeks. All groups got normal diet and water ad libitum. Plasma MDA level was measured by TBARS method, then analyzed using Kurskal-Wallis and Mann-Whitney tests.Results: Seventeen samples were successfully decapitated (5 for control; 6 for week 1; 3 for week 2; 3 for week 3). Average plasma MDA level for control treatment week 1, 2 and 3 groups were 0.707 nmol/ml, 0.432 nmol/ml, 0.312 nmol/ml, and 0.746 nmol/ml respectively. Data was significant (p<0.05) with p=0.02. Compared with control group, a significant increase occurred in week 1 and 2 groups with p=0.028 and p=0.025 respectively.Conclusions: Results of durian consumption show MDA level significantly decreases in week 1 and 2. However, MDA level dramatically increases exceeding control group level in week 3. [AMJ.2016;3(1):22–8] DOI: 10.15850/amj.v3n1.695
Visualization of Carotid Doppler in Patients with Ischemic Stroke at Dr. Hasan Sadikin General Hospital Bandung Year 2016-2019 Olivia Olivia; Ahmad Rizal Ganiem; Syarief Hidayat
Althea Medical Journal Vol 8, No 3 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n3.2285

Abstract

Background: Various pathological changes in both the intra and extracranial arteries that supply the brain can cause disturbance of cerebral blood flow and perfusion leading to cerebral dysfunction. Doppler ultrasound is able to assess these changes. This study was performed to evaluate the anatomical and physiological changes found in the carotid arteries of patients with ischemic stroke using Doppler ultrasound.Methods: The cross-sectional descriptive study design with total sampling method was conducted on the medical records of ischemic stroke patients who had carotid Doppler ultrasound at the Department of Cardiology and Vascular Medicine Dr. Hasan Sadikin General Hospital Bandung from 2016 to 2019. Demographic data, such as stroke diagnoses and plaque characteristics recorded in the Doppler reports were collected.Results: There were 38 data sets collected. The distribution and characteristics of atherosclerotic plaques were similar between the two carotid systems, with the same percentage of plaque being found in the right (31.6%) and left (36.8%) carotid system. The most common type of plaque found was type III and was located in the common carotid artery. Thrombus was absent in all patients. Intimal media thickening was found in 13.2% right system and 15.8% left system. Stenosis was present in 34.2% of patients, and most had <50% stenosis. Peak systolic velocity increased (>125 cm/s) in 5.3% of the right system and 7.9% of the left system of the internal carotid artery.Conclusions: Most of the atherothrombotic and thromboembolic type of ischemic stroke patients in this study have normal carotid Doppler ultrasound features. Further study on the presence of plaque in ischemic stroke patients in Indonesia is needed.
Co-Authors - Erwinanto, - Achmad Fauzi Yahya, Achmad Fauzi Achmad Shidiq, Achmad Ahmad Rizal Ganiem Akbar, Mohammad Rizki Amelia, Cindy Putri Amilia Nabhila Anak Agung Gede Sugianthara Ani Melani Maskoen Anugrah Aulia Ulil Amri, Anugrah Aulia Ulil Arlette Suzy Puspa Pertiwi Aryani, Dwi Destaria Augustine Purnomowati Aulia, Disya Jasmine Aulia, Mohammad Sidqi Badai Bhatara Tiksnadi Chaerul Achmad Cindy Putri Amelia Decruz, Ashley Ann Decruz, Ashley Ann Dewi, Triwedya Indra Dian Anggraeni Dini Rostiati, Dini Dwiyanti, Tsabitah Mariyah Eka Chemiawan Eriska Riyanti Gildasya Gildasya Hadiana, Hadiana Hutabarat, Debora Inne Suherna Sasmita Irham Rasyid Ismail, Muhammad Taofik Jakobus Runkat, Jakobus Januar Wibawa Martha Januarsih Iwan Rachman, Januarsih Iwan Julius B. Dewanto, Julius B. Jungjunan, Ridho Kamarullah, William Karwiky, Giky Kusumawardhani, Nuraini Yasmin Laniyati Hamijoyo Lestari, Tria Mahisa, Delvia Shafa Meirina Gartika Miryasandra, Astari Mirza, Try Ahmad Mohammad Iqbal Muhammad Rizki Akbar, Muhammad Rizki Mungkas, Ihfa Nabhila, Amilia Olivia Olivia Pintoko Tedjokusumo, Pintoko Pranata, Raymond Putri, Fadillah Amanda Raharjo, Pradana Pratomo Rahyono Rahyono Rama Nusjirwan Ramadhani, Revanti Ramadhani, Revanti Rezkita, Aliya Rahmadewi Risti Saptarini Primarti Roosje Rosita Oewen, Roosje Rosita Ruseka, Fahmi Damarjati Sativa, Liariza Sheila Sumargo, Sheila Toni Mustahsani Aprami, Toni Mustahsani Vani, Wulan Septio Wuri Handayani Wuryanti, Lestari Yahya­, Achmad Fauzi Yetty Herdiyati Yetty Herdiyati, Yetty