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All Journal International Journal of Public Health Science (IJPHS) MEDIA MEDIKA INDONESIANA Jurnal Kedokteran Diponegoro Mutiara Medika: Jurnal Kedokteran dan Kesehatan Medica Hospitalia Risenologi Psychiatry Nursing Journal (Jurnal Keperawatan Jiwa) Diponegoro International Medical Journal (DIMJ) Neurona
Amin Husni
Department Of Neurology, Faculty Of Medicine, Universitas Diponegoro Semarang, Indonesia
Chemistry Dentistry Education Engineering Health Professions Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Journal : Medica Hospitalia

 1 
The Relationship Between Pre-Operative Clinical Characteristics With Changes In Post-Operative Memory Scores On Temporal Lobe Epilepsy Patient Bintoro, Aris Catur; Arifin, Muhammad Thohar; Harsono, Harsono; Muttaqin, Zainal; Hadisaputro, Soeharyo; Husni, Amin; Bakhtiar, Yuriz; Karlowe, Vega; Pratomo, Joko
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 1 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i1.844

Abstract

Background: Most temporal lobe epilepsy (TLE) will become seizure-free after anterior temporal lobectomy (ATL) surgery but often result in cognitive decline, specifically in verbal or visual memory. Objective: This study examined the relationship between several demographic characteristics and pre-operative clinical conditions with changes in pre-post surgical memory of TLE patients. Methods: This study used a retrospective cohort in which the subjects were TLE patients who had undergone ATL surgery at Kariadi Hospital or Telogorejo Hospital, Semarang. Demographic variables include the age of onset, duration of illness, level of education, and clinical variables include seizure frequency, EEG waveform, number of AED, lesion site, and IQ score. Results: Memory re-examination was conducted on TLE patients who had undergone surgery between 2018 and 2021, with 55 subjects who fulfilled the criteria. Characteristics of the subjects were male 31(56%) males, 38% Senior High School education, the mean age of onset was 13,87±6,899, age at surgery was 27,67±9,802, 21 (39%) normal pres-surgical EEG waveform, 31 (56%) lesion on the left and the most frequent seizures occurred in 36 subjects (65%). Statistical test results showed a significant relationship between age of onset and changes in verbal memory recognition scores (p 0.044), lesion side with changes in verbal memory task scores (p 0.018), recall (p 0.005), recognition (0.008), and IQ scores with changes in visual memory construction recall (p 0.041) Conclusion: Age of onset, lesion side, and IQ score characteristics were related to the changes in memory scores between pre- and post-operative anterior temporal lobectomy in TLE patients.
Pain Improvement Among Chronic Lumbar Disc Herniation Patients Underwent Epidural Triamcinolone With Or Without Hyaluronidase Injection Within 3 Months Of Follow-Up: A Prospective Study Budisulistyo, Trianggoro; Husni, Amin; Tugasworo, Dodik; Pudjonarko, Dwi
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 1 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i1.850

Abstract

Background Chronic lumbar disc herniation (CLDH) will accompany by chronic inflammation, so the fibrosis tissues formed in the epidural space and adjacent nerve roots, and lead to mixed pain syndrome. Objectives To compare between triamcinolone only and hyaluronidase 1500 international unit (IU) administration epidural injection for treating bulged or protrusion CLDH.     Methods This prospective study involved CLDH patients visiting the outpatient department of Neurology at Dr. Kariadi Hospital Semarang Indonesia from November 2021 until August 2022. They divided: triamcinolone (Group 1) and hyaluronidase 1500 IU and triamcinolone epidural injection (Group 2) with 3 days of hospitalization. Neurotrophic was prescribed during 3 months of follow-up and ordered for personal physical treatment. They analyzed pain improvements (NRS and Pain DETECT), and the Oswestry Disability Index (ODI) scores. Results The 37 subjects were recruited but 1 female dropped out cause of re-injection, so 13 males and 23 females aged between 24 to 72 years old (mean 48+2) were followed. They significantly improved (Wilcoxon test p=.000), as the NRS score was 47.9% (Group 1) and 55.4% (Group 2). ODI scores without significance (Mann-Whitney p> .005), such at 2 weeks (group 1= 20.4%, group 2= 23.6%) and 3 months (group 1= 58.1%, group 2= 53.7%). They observed nociceptive and neuropathic improvement even though needed more time for the healing process. Conclussions This study proved hyaluronidase administration before triamcinolone epidural injection with better improvements for treating bulged or protrusion CLDH patients.
The Wistar Rat Parietal Lobe Cell And Pain Perception Changes After Frequent Of Mobile Phone Electromagnetic Wave Expose Tamad, Fatiha Sri Utami; Budisulistyo, Trianggoro; Husni, Amin; Retnaningsih, Retnaningsih; Suryawati, Herlina; Suryadi, Suryadi
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 2 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i2.884

Abstract

Background: The increasing number of mobile phone users raises concerns about the effects. Mobile phone electromagnetic wave radiation harms pain perception due to granular cell changes in the cerebral parietal cortex. Objective: To determine the effect of exposure to electromagnetic waves mobile phone on pain perception due to changes in the granular cells of the cerebral parietal cortex Wistar rats. Methods: Experimental research using randomized posttest with control group design. Samples were 28 rats divided into 4 groups. The control group was not exposed, the treatment group was exposed to 2100 MHz electromagnetic waves for 2 hours/day with a distance of 3 cm for 15 days in treatment group 1, for 30 days in treatment group 2, and 45 days in treatment group 3. Measurement of pain onset using the hot method. Changes in pain threshold were taken from the difference in pain onset after exposure to before exposure. Granular cell changes in the cerebral parietal cortex were assessed from the total score with the provisions of normal cells (sumx0), hydropic degenerated cells (sumx1), and necrotic cells (sumx2). Results: The longer the exposure to mobile phones, the higher the pain threshold and the cerebral parietal cortex granular cell damage score. There was a significant difference in pain threshold and changes in cerebral parietal cortex granular cells between groups (p=0.000). There was a significant relationship between changes in the parietal cerebral cortex granular cells and pain threshold in Wistar rats exposed to electromagnetic waves (p=0.000). Conclusion: Exposure to mobile phone electromagnetic waves affects pain perception due to changes in the granular cells of the cerebral parietal cortex in wistar rats.
The Relationship Between Serum Folic Acid Levels With The Cognitive Function of The Elderly Hermanto, Hermanto; Muhartomo, Hexanto; Husni, Amin; Widiastuty, Maria Immaculata; Suryawati, Herlina; Wati, Arinta Puspita
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 2 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i2.891

Abstract

Background: Cognitive decline is a common condition that occurs in the elderly. One of the early indicators of senility is a decrease in cognitive function. Folic acid is thought to protect the arteries from damage because of homocysteine by converting homocysteine into cysteine and then excreted in the urine. Increased levels of homocysteine can interfere with vascular function and cause toxic effects on neurons thereby increasing the risk of cognitive decline. Objective: To determine the relationship between serum folic acid levels and cognitive function of the elderly. Method: Analytical descriptive research with a cross-sectional approach. The research subjects were the elderly who met the inclusion criteria and did not have exclusion criteria. The research was conducted from May to July 2022 at the Pucang Gading Nursing Home, Semarang. Serum folic acid levels were examined using the ELISA (Enzyme-linked immunosorbent assay) method. Cognitive function was assessed using the Indonesian version of the Montreal Cognitive Assessment (MoCA) simultaneously on the subject. Cognitive function is normal if the MoCA-INA value is ≥ 26 and it is said to be cognitive dysfunction if the MoCA-INA value is < 26. Data were analyzed using the Spearman test. Results are considered significant if the value of p <0.05.  Result: There is a strong positive correlation between serum folic acid levels and cognitive function in the elderly (r=0.914, p<0.001). There is a relationship between educational level and cognitive function (r=0.922, p<0.001) where higher education correlates with increased cognitive function in the elderly. Conclusion: There is a significant positive correlation between serum folic acid levels and cognitive function in the elderly
Effect Of Triamcinolone Trigger Point Injection On Changes In TNF-α Levels And Oswestry Disability Index (ODI) Scores Non-Specific Low Back Pain (LBP) Patients Fakih, Mohamad; Suryadi; Tugasworo, Dodik; Pudjanarko, Dwi; Husni, Amin; Budisulistyo, Trianggoro; Puspitawati, Arinta
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 1 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i1.976

Abstract

Background: Low back pain (LBP) is the most common musculoskeletal problem and a major cause of worldwide disability causing increased health costs and indirect costs associated with reduced or lost productivity. One of the therapeutic management of LBP is Triamcinolone trigger point injection. Until now, research on the effect of Triamcinolone trigger point injection on changes in TNF-α levels and Oswestry Disability Index (ODI) scores in Non-Specific LBP patients is still limited. Objective: To analyze the effect of Triamcinolone trigger point injection on changes in TNF-α levels and ODI scores before and after Triamcinolone trigger point injection in Non-Specific LBP patients. Methods: This is a quasi-experimental analytic observational study with a pre and post-test group design approach. Subjects were diagnosed with Non-Specific LBP who had met the inclusion criteria (acute pain less than 3 months, patient age 30-55 years, moderate-severe pain intensity, had never received a Triamcinolone trigger point injection) with the exclusion criteria patients experiencing severe pain. not only caused by NPB. The study subjects were checked for TNF-α levels and ODI scores before and after the Triamcinolone trigger point injection. Then a paired T-test was carried out. Results: During the study period September - November 2022 at the Neurology Outpatient Polyclinic, RSUP Dr. Kariadi Semarang obtained 32 subjects. There was a significant difference between changes in TNF-α levels before and after Triamcinolone trigger point injection (p=0.000). There was a significant difference in ODI scores before and after the Triamcinolone trigger point injection (p=0.000). There was no significant relationship between the risk factors for gender, occupation, BMI, physiotherapy, and changes in TNF-α levels with changes in the ODI score. Conclusion: There is a significant difference in changes in TNF-α levels and ODI scores before and after Triamcinolone trigger point injection.
Gait Analysis of Ankle Joints of Indonesians at Low, Medium and High Speeds Novriansyah, Robin; Hadi, Jason Reynald; Bakhtiar, Yuriz; Husni, Amin; Ismail, Rifky
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 3 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i3.1175

Abstract

Background : Amputation is a loss of body part, and most amputations are lower extremity amputations. The most common is transtibial amputation. After an amputation a person will need a prosthesis. However, up to now there has been no functional prosthesis specifically made for Indonesians who undergo transtibial amputation because the ankle joint gait data that are currently used are European gait data. So it is necessary to measure the normal gait data of Indonesians' ankle joint. The aims of this study was to measure the normal gait data of the ankle joint of Indonesian population Methods : The Research sample is Indonesians aged 18–26 years with normal gait measured by the 2DMA (two-dimensional motion analyzers) at low, medium and high speeds. The resulting data is searched for the mean and standard deviations and then an independent t-test is performed between normal gait data of Indonesians and Europeans Results : Indonesians have a range of maximum dorsiflexion values for low, medium, and high speeds of : 7.9°, 8.3°, 8.9° and maximum plantar flexion for low, medium, and high speeds of 13.4°, 20.6°, 26°. In the comparison test there was a significant difference between the maximum plantar flexion angle of Indonesians and Europeans. Conclusion : Indonesians have a range of maximum dorsiflexion values for low, medium, and high speeds of 7.9°, 8.3°, 8.9° and maximum plantar flexion for low, medium, and high speeds of: 13.4°, 20.6°, 26°. There is a difference between the normal gait of the ankle joint of Indonesians and Europeans.
Co-Authors -, Retnaningsih Anjani, Gemala Ardhini, Rahmi Arinta Puspita Wati, Arinta Puspita Aris Catur Bintoro Aris Catur Bintoro Bakhtiar, Yuriz Budisulistyo, Trianggoro Darmawan, Taufan Citra Daynuri, Riri Dian Ratna Sawitri Dodik Tugasworo Dwi Pudjonarko Endang Kustiowati Endang Kustiowati Fakih, Mohamad Farichah Hanum Hadi, Jason Reynald Harsono Harsono Hartono, Jimmy Eko Budi Hermanto Hermanto Hexanto Muhartomo, Hexanto Iva Puspitasari, Iva Jaeri, Santoso Joko Pratomo, Joko Karlowe, Vega Krisninda Anggonowati M Nancye, Pandeirot M.I. Widiastuti Muhammad Thohar Arifin Nancye, Pandeirot Marjory Nani Maharani Ngadiran, Antonius Novriansyah, Robin Pandeirot, Nancye Pudjanarko, Dwi Puspitawati, Arinta Rahmawati, Maria Belladonna Rahmi Ardhini Ratna Sawitri, Dian Retnaningsih Retnaningsih Rifky Ismail Soeharyo Hadisaputro Suryadi Suryadi Suryadi Suryawati, Herlina Tamad, Fatiha Sri Utami Tikalaka, Elisabeth Romana Tori, Marthin Tranggono Yudo Utomo Widiastuty, Maria Immaculata Zainal Muttaqin