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Journal : Jurnal Penelitian Pendidikan IPA (JPPIPA)

Toothpaste Formulation Ethanol Extract Mangosteen Peel (Garcinia mangostana L.) and Test Activity Against Candida albicans Junuda, Nur Khairun Nisa; Pakki, Ermina; Ida, Nur
Jurnal Penelitian Pendidikan IPA Vol 9 No 6 (2023): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i6.3623

Abstract

The mangosteen peel contains phenol compounds that have antifungal activity. The study aimed to find out the antifungal activity in the dosage form of toothpaste against Candida albicans. The research methods used include the extraction of mangosteen peel (Garcinia mangostana L.) by maceration using 96% ethanol. The toothpaste formula was composed with an extract concentration of 1.25% (F1); 2.5% (F2); 5% (F3); and base (B). Antifungal testing was carried out by diffusion method using Potato Dextrose Agar (PDA) media. The results showed that the toothpaste formula with a concentration of F1; F2; F3; and base (B) has an average value of successive inhibition zone diameters of 11.86 mm; 12.03mm; 12.54mm; and 7.78 mm. The conclusion of the study showed that the toothpaste preparation of the ethanol extract of mangosteen fruit peel (Garcinia mangostana L.) concentration was 1.25%; 2.5%; 5% which performs antifungal activity.
Amino Acid Content Profile and Antioxidant Activity Test of Spirulina Platensis Bioactive Protein Extract Using DPPH Method Hasan, Tahirah; Ida, Nur; Yasir, Yasnidar
Jurnal Penelitian Pendidikan IPA Vol 11 No 4 (2025): April
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i4.10916

Abstract

The study of Amino Acid Content Profile and Antioxidant Activity Test of Spirulina platensis Bioactive Protein Extract with DPPH Method has been conducted. This study aims to determine the protein content and IC50 value of Spirulina platensis bioactive protein extract with DPPH method. The research method includes extraction of Spirulina platensis powder using buffer A solvent. Determination of protein content with Lowry method using Bovine Serum Albumin (BSA) as standard solution and antioxidant activity test with DPPH method. The results of the analysis of protein content of Spirulina platensis extract obtained a level of 39.51%. The antioxidant activity test against DPPH free radicals showed that Spirulina platensis protein extract has antioxidant activity with IC50 value of 599.17 ± 3.75 ppm.