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the effect of ozonated olive oil on the number of neutrophil cells in the gingiva of male Wistar rats experiencing periodontitis (in vivo) Anwaristi, Aprilia Yuanita; Cahyani, Cahyani; Faizah, Ariyani; Fauziyah, Nida Faradisa; Arifin, Dani Fajar; Hidayanti, Nur; Lestari, Cindy
Odonto : Dental Journal Vol 11, No 1 (2024): July 2024
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.11.1.21-29

Abstract

Background: Periodontal tissue, comprising gingiva, periodontal ligament, cementum, and alveolar bone, supports and surrounds teeth. Periodontitis, an inflammation affecting these tissues, manifests through gingival inflammation, pocket formation, and loss of attachment and bone.Purpose: This research aims to investigate whether ozonated olive oil influences neutrophil cell levels in the gingiva of male Wistar rats with periodontitis.Method: Employing a posttest-only control group design, this laboratory study included 24 male Wistar rats with concentrated periodontitis divided into six groups based on the day of observation. Histological analysis was conducted on days 1, 3, and 5, with three control groups and treatment groups.Result: The hypothesis test revealed a significant difference in neutrophil cell count between the ozonated olive oil treatment group and the control group (p < 0.05). The treatment group exhibited superior outcomes compared to control and other treatment groups, as confirmed by the LSD Post Hoc Test (p < 0.05).Conclusion: Administration of ozonated olive oil can influence neutrophil cell involvement in periodontitis healing among male Wistar rats, suggesting its potential therapeutic efficacy
The Potential of Habbatussauda (Nigella sativa) Effervescent Tablet Extract as a Denture Cleanser against the Growth Inhibition of Staphylococcus aureus on Acrylic Resin Plates Faizah, Ariyani; Rochmanita Suparno , Nilasary; Mahaningrum, Gunasti; Marsetyawan Dani Artha, Antony
Jurnal Kesehatan Gigi Vol. 12 No. 2 (2025): December 2025
Publisher : Jurusan Kesehatan Gigi, Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkg.v12i1.13513

Abstract

Chemical cleaning of dentures using a denture cleanser is essential to prevent denture stomatitis—an infection of the oral mucosa caused by bacteria such as Staphylococcus aureus adhering to the denture base. One key component of denture cleansers is an antibacterial agent. Habbatussauda (Nigella sativa) contains antibacterial compounds that may serve as an alternative active ingredient in denture cleansers. This study aimed to evaluate the potential of effervescent tablets containing Habbatussauda extract as a denture cleanser in inhibiting Staphylococcus aureus growth on acrylic resin denture bases. The study employed a true experimental, post-test-only control group design, using 24 acrylic resin plates divided into six treatment groups: Habbatussauda extract concentrations of 9%, 12%, 15%, and 18%, along with positive and negative controls. Each plate was immersed in the respective Habbatussauda-based denture cleanser solution for 15 minutes. Researchers then counted the bacterial colonies using a colony counter. The Kruskal-Wallis test yielded a significant difference in colony counts (p < 0.05). Post hoc analysis with Bonferroni correction revealed significant differences between the 12% and 18% extract groups, as well as the positive control, compared to the negative control. However, no significant differences emerged between the extract groups (9%, 12%, 15%, and 18%) and the positive control. These findings indicate that Habbatussauda extract-based denture cleansers effectively inhibit Staphylococcus aureus growth on acrylic resin denture bases after 15 minutes of immersion. 
Uric Acid as a Significant Risk Factor for Hypertension Severity, Unlike Lipid Profiles Basuki, Sri Wahyu; Triastuti, N Juni; Erna Herawati; Sintowati, Retno; Faizah , Ariyani; Anisa Putri, Dede; Amalia, Raisya; Embiysne , Viamell; Amalia, Regal; Kusuma Ningrum, Sukma
Jurnal Kedokteran Brawijaya Vol. 34 No. 1 (2026)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2026.034.01.5

Abstract

Hypertension remains a global health problem experienced by the world's population, as evidenced by its high prevalence and mortality rate. For 90-95% of hypertension sufferers, the cause of hypertension was reported as unknown. However, there are several risk factors associated with hypertension, notably genetic factors, age, gender, diabetes mellitus, lifestyle and diet, as well as lipid and uric acid profiles. This study aims to analyze uric acid and propyl lipid levels with hypertension severity. The study employed a quantitative research design. Data were collected through purposive sampling, yielding a total sample of 110 participants. The dataset was subsequently analyzed using logistic regression test. Based on the logistic regression statistical test, the following results were obtained: uric acid levels (p-value <0.05; OR >1; CI did not exceed 1); triglyceride levels (p-value >0.05; OR >1; CI exceeded 1); total cholesterol levels (p-value >0.05; OR <1; CI exceeded 1); and low-density lipoprotein levels (p-value >0.05; OR >1; CI exceeded 1). Thus, it can be concluded that abnormal uric acid levels significantly affect the severity of hypertension. Abnormal triglyceride levels and low-density lipoprotein levels show a tendency to increase the risk of hypertension severity but are not yet statistically significant. There is a tendency for abnormal total cholesterol levels to be less risky for severe hypertension compared to normal total cholesterol levels, but this disparity is not significant. Nevertheless, the probability of all variables with abnormal levels possessed a 12% risk of hypertension severity remains.
Gingival Curettage Treatment in a Case of Chronic Periodontitis: A Case Report Dani Fajar Arifin; Ariyani Faizah; Qitarah Safa Haqiqah
Jurnal EduHealth Vol. 17 No. 01 (2026): Jurnal EduHealt, January-March 2026
Publisher : Sean Institute

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Abstract

Chronic periodontitis is an inflammatory disease that leads to the progressive destruction of the supporting tissues of the teeth, resulting in clinical signs such as gingival redness, bleeding, and periodontal pocket formation. One of the treatment approaches commonly used to manage this condition is gingival curettage, a procedure aimed at removing inflamed and necrotic tissue from the gingival wall to promote healing and restore periodontal health. This case report describes the management of chronic periodontitis in a 21-year-old patient who presented with a complaint of persistent gingival redness in the upper right anterior region for approximately three months. Clinical examination revealed erythematous gingiva surrounding teeth 12 and 13, accompanied by a positive Bleeding on Probing response, indicating active inflammation. Based on these findings, a diagnosis of chronic periodontitis was established, and gingival curettage was performed as part of the periodontal therapy. Following the procedure, the patient showed significant clinical improvement, characterized by the disappearance of gingival redness, the absence of bleeding on probing, and the resolution of gingival swelling. These outcomes suggest that gingival curettage can effectively reduce inflammation and improve periodontal tissue condition when appropriately indicated. Nevertheless, the success of this procedure is closely related to patient compliance with oral hygiene practices and regular dental follow-up. Further studies with longer observation periods are needed to evaluate the long-term effectiveness and stability of periodontal outcomes following gingival curettage.
Gingivektomi sebagai Terapi Korektif Kontur Gingiva pada Pasien dengan Malposisi Gigi (Laporan Kasus) Khoirunisa Ulayya Azizah; Ariyani Faizah
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 5 No. 2 (2026): April 2026
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v5i2.7824

Abstract

Background: Inflammatory gingival enlargement is a periodontal condition often associated with plaque accumulation and can be exacerbated by local factors such as tooth malposition. Chronic inflammatory changes can develop into a fibrotic component that does not fully regress after nonsurgical therapy, necessitating surgical intervention to restore physiological and aesthetic gingival contour. This case report aims to describe the management of gingivectomy as a corrective therapy for gingival contour in a patient with tooth malposition that did not show optimal resolution after initial therapy. Case: A 23-year-old woman presented with gingival enlargement in the anterior mandibular region accompanied by bleeding during toothbrushing. Examination revealed crowding of teeth 33–43, moderate OHI category, plaque index 32%, gingival index 1.2, and pseudopockets with an average depth of 4 mm. Initial therapy, including scaling and root planing and oral hygiene education, resulted in improvement in inflammation, but gingival enlargement persisted. Gingivectomy using the external bevel technique was performed in the area, followed by gingivoplasty and periodontal pack placement. Result: A two-week post-procedure evaluation revealed no gingival enlargement or bleeding on probing, a decrease in probing depth to an average of 2 mm, and significant improvements in hygiene and plaque index. Conclusion: Gingivectomy preceded by early-phase therapy effectively removes excess gingival tissue, reduces pseudopockets, and creates a more physiological gingival contour. Controlling etiologic factors and maintaining oral hygiene play a crucial role in successful therapy.
Mouthwash Potential of Ethanol Extract of Ajwa Date Seeds (Phoenix dactylifera L.) against Porphyromonas gingivalis Bacteria Mauriska Nada Silmi Almisky; Etny Dyah Harniati; Steffi Triany Arnov; Ariyani Faizah
Journal of Indonesian Dental Association Vol. 9 No. 1 (2026): April
Publisher : Indonesian Dental Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32793/jida.v9i1.1535

Abstract

Introduction: Periodontal disease is a major oral health problem worldwide, with Porphyromonas gingivalis recognized as one of the primary causative bacteria. Ajwa date seeds (Phoenix dactylifera L.) have potential for development as a natural mouthwash due to their antibaterial properties, which are attributed to various bioactive compounds, including flavonoids, tannins, and saponins. Objective: To evaluate the antibacterial effect of a mouthwash containing ethanol extract of ajwa date seeds (Phoenix dactylifera L.) against the growth of Porphyromonas gingivalis. Methods: This laboratory experimental study employed a post-test-only control group design. The samples were divided into five groups: a positive control, a negative control, and three treatment groups receiving mouthwash containing ethanol extract of ajwa date seeds at concentrations of 3.25%, 6.5%, and 12.5%. Antibacterial activity was evaluated using the disc diffusion method on Mueller–Hinton Agar (MHA), with six replicates for each group. Data were analyzed using one-way ANOVA followed by Tukey's Honestly Significant Difference (HSD) post hoc test. Results: Mouthwash containing ethanol extract of ajwa date seeds inhibited the growth of Porphyromonas gingivalis, as demonstrated by the formation of inhibition zones around the discs. A concentration-dependent increase in the diameter of the inhibition zone was observed. The mean inhibition zone diameters were 10.175 mm, 12.300 mm, and 14.442 mm for the 3.25%, 6.5%, and 12.5% extract concentrations. Conclusion: Mouthwash containing ethanol extract of ajwa date seeds (Phoenix dactylifera L.) significantly inhibited the growth of Porphyromonas gingivalis. The antibacterial activity in 12.5% concentration demonstrating the greatest inhibitory effect.  
Gingivektomi Pada Enlargement Gingiva Karena Malposisi Gigi Individual Salwa Safira; Ariyani Faizah
Jurnal Sehat Indonesia (JUSINDO) Vol. 8 No. 1 (2026): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

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Abstract

Gingival enlargement is defined as a common clinical sign of gingiva caused directly by plaque that causes gingival inflammation. Gingivectomy is a procedure that can be performed on patients with gingival enlargement. This case report describes the management of gingival enlargement in a case of tooth 42 due to individual tooth malposition. A 20-year-old male patient came to Soelastri Dental and Oral Hospital in Surakarta complaining of swollen gums. The complaint was felt in the upper and lower front gums. The patient was unaware of the swelling, had never received treatment, and did not experience any pain. Gingival treatment for this patient began with phase 1 periodontal therapy followed by gingivectomy. The gingivectomy treatment in this case used a scalpel instrument and the results were effective in reducing the patient's gingival enlargement. The patient was advised to undergo further orthodontic treatment to correct individual tooth malposition.
The Effect of Immersion Time on the Amount of Fluoride Release in Fluoridated Composite Resin Materials Ariyani Faizah; Nurul Salsabila; Nilasary Rochmanita Suparno
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 22 No. 1 (2026): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v22i1.10929

Abstract

Introduction: Introduction: The fluoride content in composite resin restorations can help strengthen tooth structure affected by caries. It can also prevent secondary caries through the natural remineralization process. The mechanism of fluoride release occurs when the oral cavity is in an acidic state. It produces hydroxyl ions, which play an important role in stimulating fluoride release. The release of fluoride in composite resins runs constantly over time. The purpose of this study is to determine the effect of immersion time on the amount of fluoride released by fluoride composite resin materials. Materials and Methods: This laboratory experimental study used 25 disc-shaped specimens of fluoride-containing composite resin Tetric N-Ceram Packable (Ivoclar Vivadent AG, Schaan, Liechtenstein) (2 mm thickness × 5 mm diameter). The samples were divided into five groups based on immersion time: 1, 7, 14, 21, and 28 days. Each sample was immersed in artificial saliva at pH 5.5 to simulate acidic oral conditions. The amount of fluoride released was measured using a UV–Vis spectrophotometer at a wavelength of 570 nm. Results and Discussion: Post Hoc LSD analysis showed that the 1-day immersion group differed significantly from all other groups. Significant differences were also found between the 7-day group and the 21-day and 28-day groups, as well as between the 14-day and 21-day groups compared to the 28-day group. However, no significant differences were observed between the 7-day and 14-day groups or between the 14-day and 21-day groups. Fluoride release tended to decrease as immersion time increased. Conclusion: Immersion time significantly affects the amount of fluoride released from fluoride-containing composite resin materials.