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Identifikasi Prednison dan Piroxicam dalam Jamu Pegel Linu di Yogyakarta dengan Metode Kromatografi Lapis Tipis Burhan, Amelia Handayani; Irianto, Iramie Duma Kencana; Indraswari, Laksita Putri; Saputri, Lintang Handoyo
Jurnal Ilmu Kesehatan Bhakti Setya Medika Vol 9 No 2 (2024): Jurnal Ilmu Kesehatan Bhakti Setya Medika
Publisher : Politeknik Kesehatan Bhakti Setya Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56727/bsm.v9i2.141

Abstract

 Herbal medicine (Jamu) is a part of Indonesian cultural heritage passed down through generation. One of the commonly consumed “Jamu” in Yogyakarta is “Jamu Pegal Linu” (herbal medicine for aches and pains). Competition among “Jamu” producers often leads to the addition of chemicals subtances to enhance the drug’s effectiveness. This practice is strictly prohibited due to its potential adverse health effects. Prednisone and piroxicam, which are pharmaceutical compounds, are suspected to be frequently added to “Jamu Pegal Linu”. Therefore, this study aims to identify the presence of prednisone and piroxicam in “Jamu Pegal Linu” available in Yogyakarta. Sampel of “Jamu Pegel Linu” were collected using a purposive sampling method from herbal  shops in the Yogyakarta area. The samples were extracted using 96% ethanol. The extracted samples were then spotted onto a TLC plate, which was placed in a saturated chamber. The mobile phase used to identify prednisone were ethyl acetate: chloroform in  ratios of 9:1, 6:4, and 8:2; whereas for piroxicam, three mobile phases were used: chloroform : acetone (80: 20), ethyl acetate : methanol : ammonia (60: 30: 10), and chloroform : methanol (100: 5). The stationary phase used was a silica gel GF254 plate. A sample was considered positive if the Rf value and the color of the spot of the spot matched those of the reference standard. The results of the study, using the thin-layer chromatography (TLC) method, showed that none of herbal medicine samples for aches and pains circulating in the Special Region of Yogyakarta contained prednisone or piroxicam. Therefore, the analyzed herbal medicine samples are considered safe for public consumption.
Formulation and Organoleptic Evaluation of Roselle (Hibiscus sabdariffa) Jamu Godog with Stability and Microbial Quality Assessment Irianto, Iramie Duma Kencana; Purwanto; Nurhaeni, Farisya; Ana Mardiyaningsih; Bangkit Ary Pratama; Fiqoh, Latifah Nisa; Febriana Ardiyanti
Journal of Fundamental and Applied Pharmaceutical Science Vol. 6 No. 1 (2025): August
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v6i1.22102

Abstract

Jamu is a traditional medicinal preparation proven to have many pharmacological properties and is widely used in Indonesian society. Unfortunately, many people do not like herbal medicine because of its unpleasant taste and odor. This phenomenon has driven much research in modifying the organoleptic parameters of jamu to make it more acceptable to the tongues and noses of consumers while still having a potent effect on health. This study, thus, aimed to formulate a roselle (Hibiscus sabdariffa)-enhanced jamu godog (traditional Indonesian herbal decoction) and evaluate its organoleptic properties, physical stability, and microbial quality. Jamu godog was prepared by sequentially boiling and mixing ground ginger, turmeric, lemongrass, roselle, rock sugar, and lime, with roselle concentrations set at 0%, 0.3%, and 0.6%. Organoleptic attributes and pH stability were assessed before and after storage at 4°C and 25°C for seven days. Microbial contamination was measured via total plate count (TPC) after storage at 4°C for three and seven days. A hedonic test with 40 participants across two age groups evaluated sensory acceptance. Results indicate that the addition of roselle at 0.3% concentration optimized taste and overall acceptability while maintaining pH stability and microbial safety within BPOM standards throughout the storage period. This formulation demonstrates potential as a palatable and microbiologically safe herbal preparation with enhanced consumer acceptance.