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All Journal Medula Juke Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Journal of Indonesian Tourism, Hospitality and Recreation Medica Hospitalia JURNAL PIONIR JK Unila (Jurnal Kedokteran Universitas Lampung) JOURNAL LA MEDIHEALTICO Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Jurnal Farmasetis Majority JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Nurul Islamy
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Journal : medula

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Kistadenoma Serosum Ovarii: Laporan Kasus Wilda Ainia Silmi Kaffah; Dhea Mutiara Karmelita; Nurul Islamy
Medula Vol 12 No 4 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i4.510

Abstract

Ovarian cystadenoma is a benign neoplasm originating from ovarian epithelium, including serous cystadenoma, mucinous cystadenoma, endometrioid, transitional clear cells (Brenner), and stromal epithelial cells. These epithelial tumors account for 60-80% of all ovarian neoplasms. Symptoms experienced by patients with ovarian cystadenoma are quite varied, depending on the type of cyst itself. The management of ovarian cystadenoma is surgical cystectomy with thorough exploration of the intrapelvic and abdominal organs. Further management is usually carried out with histopathological examination to determine the presence or absence of malignancy. Mrs. M, a 57-year-old woman was referred to Abdul Moeloek Hospital with a suspected diagnosis of ovarian neoplasm. The patient was referred for further examination and treatment. Symptoms include a lump in the stomach accompained by lower left abdominal pain since 2 months ago, often feeling nauseous since 5-6 years ago, weight loss is denied. Physical examination revealed a mass in the left lower quadrant. The results of ultrasound examination revealed a cystic mass in the left ovary. The patient was treated with pharmacotherapy and operative left salpingo oophorectomy. Postoperative diagnosis was left ovarian cystadenoma.
G3P2A0 Hamil 26 Minggu Inpartu dengan Perdarahan Trimester II e.c Mola Hidatidosa Parsial Janin Tunggal Hidup Intrauterin Riska Putri Soraya; Muhammad Caesario Liazmi; Nurul Islamy
Medula Vol 12 No 4 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i4.524

Abstract

Hydatidiform mole is an abnormal condition in pregnancy with part or all of the chorionic villi undergo hydropic degeneration. Hydatidiform mole is divided into complete hydatidiform mole and partial hydatidiform mole. The incidence rate in Indonesia is around 1:80 normal deliveries. While the incidence of partial moles is rare, the incidence varies from 5:100,000 and 1:10,000 pregnancies. Mrs. A 37 years old came to the ER Abdul Moeloek Hospital with complained abdominal pain and vaginal bleeding. Result of general examination: moderate ill appearance, blood pressure was 148/89 mmHg, other sign examination were within normal limits. On obstetric examination, the uterine fundal height was two fingers above the umbilicus, the fetal heart rate was 155x/min and three contractions in 10 minutes, the duration was 20-40 seconds. Speculum examination result : opened portio, there is a fish eyed-like bubble, and active bleeding. Ultrasound examination revealed that she was pregnant 26 weeks with a partial hydatidiform mole. Complete blood count with severe anemia. Whereas immunological and serological examinations results: β-hCG 5,242,880 mIU/mL; T3 1.93 nmol/L; T4 157, 43 nmol/L; TSH 0.01 uIU/mL. So the diagnosis is G3P2A0 26 weeks of gestational age in active phase with a partial hydatidiform mole accompanied by hyperthyroidism and severe anemia with single live fetus intrauterine. Patient lead to spontaneous vaginal delivery were then treated with curettage, transfusion and postpartum care. Furthermore, the mole tissue was taken for Anatomical Pathology examination and the patient was planned to control for the β-hCG evaluation.
G4P2A1 Hamil 38 Minggu Belum Inpartu dengan HAP e.c Plasenta Akreta dengan Riwayat SC Satu Kali, Janin Tunggal Hidup, Letak Lintang : Sebuah Laporan Kasus Fukrapti Fukrapti; Restu Krisnanda; Nurul Islamy
Medula Vol 12 No 4 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i4.594

Abstract

Placenta accreta is the abnormal implantation of the placenta in the uterine wall. The risk factors for placenta accreta include a history of myometrial damage due to cesarean section, placenta previa, maternal age > 35 years, and multipara. Meanwhile, the transverse lie is when the position of the fetus is perpendicular to the mother. The predisposition factors for transverse fetal position are multipara, placenta previa, and uterine myoma. Mrs. YS, G4P2A1, 32 years old, was referred from Way Kanan Hospital with bleeding from the genitals 3 weeks before she entered to the hospital. The bleeding was fresh red, no pain, 3 times changing pads per day. The patient was diagnosed with placenta accreta at 6 months of gestation. Examination of vital sign, general physical examination, and complete haematological examination were within normal limits. Obstetrical physical examination revealed fundal height of 3 fingers bellow the Xyphoideus Processus with estimated fetal weight of 2.790 gram, and transverse lie. Ultrasound results showed the impression of a single live fetus in a transverse position, biparietal diemeter indicated 38 weeks 3 days of gestational age with the placenta closing the OUI, pathological lacunae, hypervascularization, and bridging vessels. The patient underwent laparotomy and total hysterectomy. Postoperatively, ceftriaxone 1 gram/12 hours IV therapy, tranexamic acid 500 mg/8 hours IV, ketorolac 30 mg/8 hours, and transfusions of 2 PRC and 2 WB kolf were given. Post-transfusion haemoglobin 10.8 g/dL.
Hubungan Usia, Paritas, Penyakit Infeksi Dan Status Gizi Ibu Terhadap Kejadian Kelainan Kongenital Mayor pada Janin Zahra Dewi Hasna Difa; Khairun Nisa; Betta Kurniawan; Nurul Islamy; Rodiani -
Medula Vol 13 No 3 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i3.668

Abstract

Major congenital abnormalities refer to medical and cosmetic abnormalities that require surgery and are a leading cause of mortality among children under the age of five in Indonesia. Several risk factors contribute to congenital abnormalities, including the mother’s age, parity, infectious diseases, nutritional status, environment, education, and employment. This study aims to determine the relationship between age, parity, infectious diseases, and nutritional status of mothers and the occurrence of major congenital abnormalities. Secondary data from medical records of mothers who received treatment in the delima room at RSUD Dr. H. Abdul Moeloek were analyzed using an observational analytic method and a cross-sectional approach. The chi-square test and odds ratio values were used to test the major congenital abnormalities' relationship with the risk factors. Results showed that there was a significant association between nutritional status, infectious diseases, and parity with the incidence of major congenital abnormalities (p = 0,004; OR = 0,086; 95% CI = 0,016-0,468), (p = 0,034; OR = 6,816; 95% CI = 1,288 – 36,062) and  (p = 0,005; OR = 9,567; 95% CI = 1,549 – 30,206), but not with maternal age (p = 0,724; OR = 1,333; 95% CI = 0,322 – 5,526). The incidence of major congenital abnormalities is related to nutritional status, infectious diseases, and parity, but not to maternal age. 
P3A0 Perdarahan Pasca Persalinan Pervaginam et causa Atonia Uteri: Laporan Kasus Alandra Rizhaqi Vastra; Ikhlas Taufik; Nurul Islamy
Medula Vol 13 No 6 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i6.809

Abstract

Postpartum haemorrhage is a state of blood loss >500 ml through vaginal delivery, or >1000 ml in caesarean section after delivery. One of the most common causes of postpartum hemorrhage is uterine atony. Uterine atony is a condition of weak uterine tone that causes the uterus to be unable to close the bleeding from the placental implantation site after the baby and placenta are born. Mrs. RF, 36 years old, came to the ER of RS Abdul Moeleok with postpartum bleeding since ± 2 hours before entering the hospital. The patient gave birth vaginally with the help of a midwife and experienced postpartum bleeding due to the absence of adequate uterine contractions (uterine atony) after delivery. The patient was treated with oxytocin and misprostol and the bleeding was resolved.
GAMBARAN PENGETAHUAN MAHASISWA FAKULTAS KEDOKTERAN PROGRAM STUDI PENDIDIKAN DOKTER UNIVERSITAS LAMPUNG ANGKATAN 2021 TERHADAP ANESTESI DAN PERAN DOKTER SPESIALIS ANESTESI Javinka Fairuz Zahrani; Liana Sidharti; Nurul Islamy; Bambang Eko Subakti
Medula Vol 13 No 7 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i7.849

Abstract

Anesthesia is an action in the medical field that is carried out intentionally on healthy patients and patients who have a disease from mild to severe with the aim that the patient does not feel sick when surgery is performed. This study aims to describe the knowledge of students of the Faculty of Medicine, Medical Education Study Program, University of Lampung on anesthesia and the role of anesthesiologists. This study used a descriptive cross-sectional research method on 136 samples selected through simple random sampling technique. The study used a questionnaire given via google form. The data were analyzed univariately to describe the knowledge of students of the medical faculty of the Lampung University medical education study program on anesthesia and the role of anesthesiologists. The results showed that 12 respondents (8.8%) had good knowledge, 54 respondents (39.7%) had sufficient knowledge, and 70 respondents (51.5%) had less knowledge about anesthesia and the role of anesthesiologists. . The conclusion in this study was that students of the medical faculty of the Lampung University medical education study program class of 2021 still lacked knowledge about anesthesia and the role of anesthesiologists.
Penggunaan Tanaman Mangrove Sebagai Obat Herbal di Lampung Selatan Rodiani, Rodiani; Islamy, Nurul
Medula Vol 14 No 5 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i5.1085

Abstract

As a means of adaptation to extreme habitats, mangrove plants produce a variety of secondary metabolic substances that have the potential as herbal medicines. Empirically, coastal communities have utilized and proven the medicinal properties of mangrove plants. The study’s objective was to determine the use of mangrove plants as herbal medicine in Pematang Pasir, South Lampung. The use of mangroves as medicine was obtained through in-depth interviews followed by descriptive analysis and calculation of species use value, plant part value, and fidelity level. The results showed that the use of mangrove plants as herbal medicine in the Pematang Pasir area, Ketapang District, South Lampung, ethnically dominated by the Serang ethnic group (54%), with the majority having completed junior high school education (38.1%), economically classified as middle-income based on BPS criteria (2020), with the majority working as fishermen and farmers, and the majority being adults (over 40 years old). Based on the Species Use Value (SUV), R. apiculata is the most popular and widely used species by the community. Based on Plant Part Value (PPV) analysis, leaves are the most commonly used part as herbal medicine, with over 75% of the population using mangrove leaves as a source of treatment, while other parts are less utilized. The level of community trust in the benefits of mangrove plants as medicine is relatively low, with figures below 50%. Rhizophora apiculata is the only species accepted with a high level of confidence of 88%, particularly as a wound or antiseptic medicine.
Hubungan Disfungsi Endotel dengan Preeklamsia Gejala Pemberat Angelie Cahya Putri; Nurul Islamy; Anisa Nuraisa Jausal; Suharmanto Suharmanto
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1777

Abstract

Preeclampsia with severe features is a major pregnancy complication contributing substantially to maternal and perinatal morbidity and mortality worldwide. This condition primarily arises from impaired placentation that leads to placental hypoperfusion and the release of anti-angiogenic factors such as sFlt-1 and soluble endoglin, which suppress pro-angiogenic activity of VEGF and PlGF, ultimately triggering systemic endothelial dysfunction. This review aims to analyze the relationship between endothelial dysfunction and the pathophysiological mechanisms of severe preeclampsia through current scientific literature. A narrative literature review was conducted, examining clinical and molecular studies related to angiogenesis, oxidative stress, inflammation, and biomarkers influencing disease progression. The findings indicate that angiogenic imbalance, increased oxidative stress, inflammatory activation, and hemodynamic alterations are key drivers of endothelial injury, resulting in hypertension, proteinuria, edema, and multi-organ involvement. Additionally, the sFlt-1/PlGF ratio is identified as a strong predictor of disease severity and progression toward severe preeclampsia. The discussion highlights that deeper understanding of endothelial mechanisms provides promising pathways for developing early screening tools and targeted therapeutic strategies. Thus, endothelial dysfunction represents a central component in the pathogenesis of severe preeclampsia and remains critical for improving detection and clinical management.
Co-Authors Ade Yonata Ade Yonata, Ade Afrianza Dafi Ramadhan Agustyas Tjiptaningrum Ahmad Fauzi Akhmad Yogi Pramatirta, Akhmad Yogi Alandra Rizhaqi Vastra Amillia Siddiq Angelie Cahya Putri Anisa Nuraisa Jausal Arli Suryawinata Aziz, M. Alamsyah Bambang Eko Subakti Betta Kurniawan, Betta Dani Setiawan Dhea Mutiara Karmelita Edi Kurniawan Efriyan Imantika Ety Apriliana Fiana Deswita Firmansyah Basir Fukrapti Fukrapti Hamidi, Syahrul Hasan Hasan Hermie Tendean Ikhlas Taufik Indri Windarti Javinka Fairuz Zahrani Julizar Mauttaqin Khaerunnisa P, Maya Khaerunnisa, Maya Khairun Nisa Kurniawaty, Evi Kusumaningtyas, Aditya Liana Sidharti Lukman Pura Lumentut, Anastasia M. Lumentut, Anastasia Mariane M Nico Hardianto M Tomy Iskandar M. Ricky Ramadhian Maelissa, Merlin Maelissa, Merlin M. Maelissa, Merlin Margreth Mahardika Putra Mallarangeng, Andi Nafisah Tendri Adjeng Marlon Brando Miftahul Husna Muhammad Caesario Liazmi Najoan, Rizki Nurmayeni Nuswil Bernolian Panjaitan, Bahmid Prabowo, Arif Yudho Puspitasari, Maya Khaerunnisa Ratna Dewi Puspita Sari Restu Krisnanda Rezita Rahma Reza Rezita Rahma Reza Rinaldy, Dino Risdianto Risdianto Riska Putri Soraya Rizki Hanriko Rodiani - Rodiani, Rodiani Rudiyanto, Waluyo Sayuti, Marzuqi Selvi Rahmawaty Setyorini Irianti Siregar, Bintang Abadi Situmorang, Ephraim Matthew Sebastian Suharmanto Syahrul Hamidi Nasution Taruna, Achmad Theodorus Theodorus Ustami Panjaitan Waluyo Rudiyanto Wilda Ainia Silmi Kaffah Wirawan, Wahyudi Zahra Dewi Hasna Difa