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I Gusti Kamasan Arijana
Departemen Histologi Fakultas Kedokteran Universitas Udayana
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Journal : Hang Tuah Medical Journal

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Potensi Kulit Jeruk Bali (Citrus Maxima Merr) Sebagai Antibakteri Propionibacterium acne Penyebab Jerawat JOHAN AXEL PARIURY; JUAN PAUL CHRISTIAN HERMAN; TIFFANY REBECCA; ELVINA VERONICA; I GUSTI KAMASAN NYOMAN ARIJANA
HANG TUAH MEDICAL JOURNAL Vol 19 No 1 (2021): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v19i1.65

Abstract

Introduction: Acne or known as acne vulgaris is an inflammation of the pilosebaceous layer with blockage of the keratin material due to the Propionibacterium acnes (P.acne) bacteria. The prevalence of acne in Indonesia is 80%-85% in adolescents. Acne appearances can cause insecurity in our look. Acne medication has irritation side effects and already resistant so other alternatives medicines are needed. The production of pomelo (Citrus maxima merr) in Indonesia reaches 511 kg annually with a weight of 208 kg of pomelo peel. About 50% of pomelo peel is removed without reprocessing even though it contains a lot of antioxidants and antibacterial properties. Aims: To know the potential of pomelo peel as an alternative antibacterial P.acne that causes acne. Methods: Literature study using research articles or literature review articles from international and national journals in 10 years. Accessed from Pubmed, Garuda, NCBI, and Google Scholar by typing keywords. Around 30 articles were used in this review article. Results: The antioxidants of pomelo peel interfere with metabolism by inhibiting the performance of the enzyme reversing RNA transcriptase, DNA topoisomerase, transporting active bacteria, disrupting PH regulation, denaturing bacterial proteins, damaging cell membranes thus inhibiting replication and causing the death of P.acne. Conclusion: Pomelo peel is considered to be an antibacterial P.acne that causes acne. Further research is needed, especially in extract concentrations and side effects.
Efek Blueberry (Vaccinium sp.) Terhadap Kelembapan Kulit yang Terpapar Sinar Ultraviolet Akut ADNYANA PUTRA, I GEDE AGUS DIVA; IDA AYU IKA WAHYUNIARI; NI MADE LINAWATI; I GUSTI KAMASAN NYOMAN ARIJANA
Hang Tuah Medical Journal Vol 21 No 1 (2023): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v21i1.337

Abstract

Introduction: Maintained skin moisture is an indication of healthy skin. Acute UV exposure can cause sunburn, which is characterized by a loss of moisture in the skin. Polyphenol compounds are one practical approach to protecting the skin from sunburn so that skin moisture is maintained. Blueberries are one of the natural ingredients consists of anthocyanin compounds, which are polyphenols from the flavonoid group. Aims: To determine the effect of blueberries on skin moisture exposed to acute ultraviolet rays. Methods: Literature study using references in the form of research articles and literature reviews from national and international journals and related books published in the last 10 years. In writing this literature review, 42 references were used which were accessed through Google Scholar, NCBI, Crossref, and Pubmed. Results: Blueberries anthocyanins can maintain skin moisture from increased transepidermal water loss (TEWL) due to acute UV ray exposure by reducing the formation of UV stimulated reactive oxygen species (ROS) and lipid peroxidation in keratinocyte cells to maintain the elastic modulus and mechanical properties of keratinocytes as well as can prevent sunburn by reducing the skin's modulation of UV exposure. However, the absorption of anthocyanin compounds in the intestine is so low that taking blueberries orally alone is not enough to achieve good biodistribution. Conclusion: Blueberries affect retaining moisture in skin exposed to acute UV rays, so they have the potential to be used as skincare ingredients. However, further research needs to be done, especially to determine the side effects that can be caused and the required extract concentration.
Co-Authors ADNYANA PUTRA, I GEDE AGUS DIVA Agus Dody Pranata Suadi Putra Anak Agung Ngurah Subawa Apolonia Berenika Badu Ayu Gita Bhagawanti Ayu Saka Laksmita W D.A.A.S. Laksmi Desak Putu Citra Udiyani Desak Putu Risky Vidika Apriyanthi Dewa Ayu Agus Sri Laksmi Dinesh Tanabbal ELVINA VERONICA Eugenia Meidy Fedik Abdul Ratam Gayathiri Mohana Krishnan Gede Wirata Hamsu Kadriyan Henky Henky I Dewa Ayu Eka Widiari Putri I Dewa Ayu Inten Primayanti I Dewa Made Agus Paramarta Putra I Gde Raka Widiana I Gusti Ayu Dewi Ratnayanthi I Gusti Ayu Dewi Ratnayanti I Gusti Kamasan I Gusti Ngurah Mayun I Gusti Nyoman Sri Wiryawan I Kadek Swastika I Ketut Tunas I Made Adi Satria Darma I Made Agus Endra Permana I Made Jawi I Made Sudarmaja I Nyoman Hariyasa Sanjaya I Nyoman Wande I Nyoman Wiryawan I Putu Dema Prasetya I Wayan Gede Artawan Eka Putra I Wayan Putu Sutirta Yasa I Wayan Sugiritama I Wayan Sugiritama I. G. A. D. Ratnayanthi I.G.N.S. Wiryawan I.N. Wande I.W. Sugiritama Ida Ayu Dewi Wiryantini Ida Ayu Ika Wahyuniari Intan Syahirah Bt Abdul Rauap JOHAN AXEL PARIURY Joshua Ezra Ronaldo Bayak JUAN PAUL CHRISTIAN HERMAN Juven Luvianto Komang Jegek Triangga Apsari Made Satria Yudha Dewangga Mahen Isaac Pannir Chelvam N. M. Linawati N.M. Linawati Ni Ketut Susilawati Ni Luh Ariwati Ni Luh Putu Eka Diarthini Ni Made Linawati Ni Made Mertaniasih Ni Made Yuli Lestari Ni Nyoman Mas Utari Rena Ni Nyoman Sri Budayanti Ni Putu Candra Paramita Ni Putu Sriwidyani Ni Putu Widayanti Ni Wayan Devi Yulianti Nyoman Intan Cahaya Pertiwi Nyoman Pratiwi Hapsari Dewi P.P.A.P. Dewi Putu Ayu Asri Damayanti Raymond Elbert Budianto Romdhoni, Achmad Chusnu Ruthirar Kalaichelvam Sri Maliawan Tarvin Jit Singh Gill TIFFANY REBECCA Tjokorda Gde Agung Suwardewa Wayan Aryadana Wayan Aryadana Wayan Suardana Yogarani V.C Rajappan