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Journal : ELECTRON (Journal of Science and Technology)

Analysis of monocyte and lymphocyte counts of TBDC patients taking anti-TBC drugs Susanti, Eka; Sugiono, Sugiono; Kamilla, Laila
ELECTRON (Journal of Science and Technology) Vol. 7 No. 1 (2025): ELECTRON (Journal of Science and Technology)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/electron.v7i1.514

Abstract

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis that attacks the lungs and spreads through the air. Monocytes and lymphocytes play an important role in the immune response to TB. Changes in their numbers can reflect the immune response and treatment effectiveness. Monitoring patients during treatment provides insight into disease progression and therapy response. This study aims to analyze the number of monocytes and lymphocytes in TB patients taking anti-tuberculosis drugs at Puskesmas Ledo, Bengkayang Regency. The study was descriptive quantitative to describe the number of monocytes and lymphocytes. The population was all TB patients undergoing treatment in the working area of Puskesmas Ledo, with total sampling technique and the number of respondents as many as 30 people. From the results of the study, 21 respondents had high monocyte counts: 8 in the early phase of treatment and 13 in the advanced phase. Meanwhile, 9 respondents had non-high monocyte counts, consisting of 4 in the initial phase and 5 in the continuation phase. Of the total respondents, 3 people had high lymphocyte counts, namely 2 in the initial phase and 1 in the continuation phase, while 27 had non-high lymphocyte counts, consisting of 10 in the initial phase and 17 in the continuation phase. In conclusion, high monocyte counts were more common in the continuation phase (61.9%), while high lymphocyte counts were more common in the early phase (66.7%).
Evaluation of the accuracy and precision of the microlab 300 device for total cholesterol test on the CHOD-PAP method Ananda, Fanny Rizki; Sungkawa, Hendra Budi; Kamilla, Laila; Fatayati, Imma
ELECTRON (Journal of Science and Technology) Vol. 7 No. 1 (2025): ELECTRON (Journal of Science and Technology)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/electron.v7i1.516

Abstract

Internal quality assurance (PMI) is a routine preventive and monitoring activity in the laboratory to minimize errors and produce accurate tests. Quality accuracy and precision are important indicators in assessing PMI. Accuracy indicates the closeness of the test results to the true value, while precision describes the closeness of the results of repeated tests on the same sample. Total cholesterol examination using a spectrophotometer, especially the CHOD-PAP method, is often carried out at the Clinical Laboratory of the Poltekkes Kemenkes Pontianak due to its stability. This observational study aims to evaluate the accuracy and precision of the Microlab 300 tool for total cholesterol examination using the CHOD-PAP method at the Integrated Laboratory of the Poltekkes Kemenkes Pontianak. The study population was the assayed control serum solution, with samples in the form of normal control serum solution dialab which was divided into 100 vials containing 50 µL. A total of 30 vials were used for the preliminary period and 30 vials for the control period. The parameter examined was total cholesterol by CHOD-PAP method. The results showed the average accuracy of the Microlab 300 tool was 96.08% and precision was 99.21%. The daily graph using Westgard's rule shows that the control material is within the control limits. Thus, it can be concluded that the Microlab 300 tool shows good accuracy and precision in the examination of total cholesterol CHOD-PAP method in the laboratory
Relationship of preeclampsia in pregnant mothers with ureum and creatinin levels Nurhadiah, Nurhadiah; Kamilla, Laila; Triana, Linda; Maretalinia, Maretalinia
ELECTRON (Journal of Science and Technology) Vol. 7 No. 2 (2025): ELECTRON (Journal of Science and Technology)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/electron.v7i2.520

Abstract

Preeclampsia is a complication of pregnancy due to increased blood pressure, accompanied by proteinuria and odema. Risk factors include primigravida, multiple pregnancy, extreme age at pregnancy, previous history of preeclampsia, family history, and diseases such as kidney, diabetes mellitus, and hypertension. The purpose of this study was to determine the relationship of preeclampsia with ureum and creatinine levels in pregnant women at RSUD Dr. Rubini Mempawah. This research is descriptive analytic with cross sectional approach. The population was all pregnant women who visited in May-July 2024 at RSUD Dr. Rubini Mempawah, with purposive sampling technique. Examination of ureum using Enzym Method and creatinine with IFCC Method. Of the 65 respondents, high ureum levels were found in 20 people (30.8%), with 7 people having preeclampsia and 13 people not. High creatinine levels were found in 21 people (32.3%), consisting of 11 people with preeclampsia and 10 without preeclampsia. Chi-Square test showed a p value = 0.438 (> 0.05) for ureum, indicating no relationship, so Ha was rejected. While p = 0.003 (<0.05) for creatinine, indicating there is an association, so Ha is accepted. In conclusion, there is no relationship between preeclampsia and ureum levels and there is a relationship between preeclampsia and creatinine levels in pregnant women at RSUD Dr. Rubini Mempawah