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All Journal Jurnal Laboratorium Khatulistiwa Media Penelitian dan Pengembangan Kesehatan ELECTRON (Journal of Science and Technology)
Nurhayati, Etiek
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Gambaran Berat Jenis Urin Dan Kadar Protein Urin Pada Ibu Hamil Di Upk Puskesmas Kampung Dalam Pontianak Timur Musaidah, Siti; Nurhayati, Etiek; Slamet, Slamet; Salim, Maulidyah
Jurnal Laboratorium Khatulistiwa Vol 5, No 2 (2022): Mei 2022
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v5i2.974

Abstract

Laboratory examinations are carried out to determine diseases that can affect pregnancy, one of the tests carried out is routine urine. The presence of the hormone HCG (Human Chorionic Gonadotrophin) in the urine can be used for a pregnancy test. Kidney function, can be known through a protein test in the urine, the presence of protein in the urine leads to pre-eclampsia in pregnant women. High urine specific gravity can be caused by lack of fluid consumption, the presence of sugar in the urine, and protein in the urine (usually in people with kidney disorders) or certain medications. This study aims to describe the description of urine specific gravity and urine protein levels in pregnant women in the UPK Puskesmas Kampung Dalam, Pontianak Timur. This is a descriptive survey research using the accidental sampling technique. Measurements and observations of research variables were measurements of urine specific gravity and urine protein content which were carried out at the UPK Laboratory of the Kampung Dalam Puskesmas, Pontianak Timur. The sample used is a urine sample when pregnant women who meet predetermined criteria, the examination is carried out using a Urine Analyzer. Respondents of this study found 30 people. The results of 30 respondents pregnant women measuring urine specific gravity whose normal limit is 1,005-1,030 obtained urine specific gravity of 1,010 as many as 6 respondents (20%), 1,015 as many as 9 respondents (30%), 1,020 as many as 2 respondents (6,7% ). 1,025 as many as 6 respondents (20%), and 1,030 as many as 7 respondents (23.3%). While the results of the measurement of urine protein levels were positive 1 as many as 4 respondents (13.3%), positive 2 as many as 1 respondent (3.4%), and Negative as many as 25 respondents with a percentage (83.3%).
Pengaruh Ekstrak Kulit Jeruk Bali (Cirus maxime Merr.) Sebagai Antikoagulan Dengan Metode Clotting Time (Lee and White) Nurhayati, Etiek; Sukma, Sherin Aulia; Wahdaniah, Wahdaniah
Jurnal Laboratorium Khatulistiwa Vol 5, No 1 (2021): November 2021
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v5i1.951

Abstract

Tanaman Jeruk Bali merupakan tanaman yang diduga memiliki kandungan sebagai antikoagulan. Ekstrak etanol kulit buah jeruk bali mengandung senyawa metabolit sekunder berupa alkaloid, flavonoid, tannin, saponin, fenol, dan minyak atsiri. Senyawa metabolit sekunder alkaloid dan flavonoid memiliki fungsi sebagai antikoagulan dengan cara menghambat jalur koagulasi secara ekstrinsik dan intrinsik melalui penghambatan produksi FXa, trombin, dan menghambat TNF-a yang diinduksi oleh PAI-1. Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak kulit buah jeruk bali sebagai antikoagulan dengan metode clotting time. Penelitian ini menggunakan desain penelitian eksperimen semu (Quasi Experiment) dengan teknik pengambilan sampel purposive sampling dengan konsentrasi 0,5%, 1%, dan 1,5% dengan pengulangan sebanyak 9 kali. Pengujian antikoagulan dengan metode clotting time untuk melihat lamanya waktu yang diperlukan darah untuk membeku. Hasil pengukuran diperoleh rata-rata dari waktu yang diperlukan darah untuk membeku dengan konsentrasi 0,5%, 1%, dan 1,5% adalah sebesar 8 menit, 9 menit, dan 10 menit. Uji Regresi Linier didapatkan nilai signifikansi p value = 0,000 < a 0,05 yang artinya Ha diterima sehingga dinyatakan ada pengaruh ekstrak kulit jeruk bali sebagai antikoagulan dengan metode clotting time (lee and white).
HUBUNGAN SEKS BEBAS DENGAN KEJADIAN SIFILIS DI WILAYAH KERJA PUSKEMAS KOM YOS SUDARSO KOTA PONTIANAK Dj, Herlinda Djohan; Sutriswanto, Sutriswanto; Nurhayati, Etiek; Ratika, Meila; Salim, Maulidiyah
Jurnal Laboratorium Khatulistiwa Vol 7, No 2 (2024): Mei 2024
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v7i2.1347

Abstract

Syphilis, also known as "the lion king", is an STI (Sexually Transmitted Infection), a disease caused by infection with the Treponema Pallidum bacteria. It is chronic and chronic. This is a dangerous disease because it can attack all organs of the body. This research was conducted at the Kom Yos Sudarso Pontianak Community Health Center because the Community Health Center is a referral health center for syphilis examinations and the respondents were people who were caught by field officers who allowed free sex.               This study aims to find out who suffers from syphilis among respondents who engage in casual sex, as well as finding out the percentage of syphilis incidents in people who engage in casual sex and to find out the relationship between casual sex and the incidence of syphilis in the work area of the Kom Yos Sudarso Community Health Center, Pontianak City.               This research design uses cross sectional with random sampling technique. The samples used were 123 patient blood samples using the TP Rapid method.               Based on the results of the research conducted, casual sex and the incidence of syphilis were obtained. The results of analysis using the chi square test using Continuity Correctionb obtained a value of p = 0.021 < 0.05, so HA was accepted so that there was a significant relationship between casual sex and the incidence of syphilis in the work area of the Community Health Center. Yos Sudarso, Pontianak City.
Gagal Ginjal Kronik Yang Menjalani Terapi Hemodialisa Di RSUD dr ABDUL AZIZ Nurhayati, Etiek; Kamilla, Laila; Lestari, cik Verra Budi
Jurnal Laboratorium Khatulistiwa Vol 7, No 1 (2023): NOVEMBER 2023
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v7i1.1246

Abstract

Hypertension is when a person experiences increased blood pressure on tissue and organ perfusion. One complication that can be caused by hypertension is kidney failure. Urea and creatinine are waste products of the body's metabolism. Ureum and creatinine levels will increase, indicating impaired kidney function. Damage that occurs to the kidneys must be treated one way with hemodialysis. The function of hemodialysis therapy is to reduce urea and creatinine levels in patients with chronic kidney failure.The study's general objective was to analyze urea and creatinine levels in hypertensive patients with chronic kidney failure undergoing hemodialysis therapy at dr. Abdul Aziz Singkawang General Hospital. The research design is analytically observational with a cross-sectional research design. Secondary data in this study were obtained from medical records and laboratory results of hypertensive patients with chronic kidney failure undergoing hemodialysis therapy without complications of DM, namely 37 respondents who performed urea and creatinine examinations before and after hemodialysis at dr. Abdul Aziz Singkawang by using a purposive sampling technique.The results of the study found 64 hypertensive patients undergoing hemodialysis and obtained a sample of 37 patients who met the criteria, namely hypertensive patients undergoing hemodialysis without complications of DM got an average urea level before hemodialysis 187.1919 mg/dl and after hemodialysis 136.0162 mg/dl. The intermediate creatinine level before hemodialysis was 14.0870 mg/dl and 11.0224 mg/dl after hemodialysis.The results of the Wilcoxon Signed Rank Test. They obtained p-value = 0.000 <α (0.05), which indicated differences in urea and creatinine levels before and after hemodialysis therapy in hypertensive patients with chronic kidney failure.
PENGARUH ANTIBAKTERI SEDIAAN SABUN WAJAH CAIR EKSTRAK ETANOL DAUN BELIMBING WULUH (Averrhoa bilimbi L) TERHADAP Staphylococcus aureus METODE DIFUSI Tumpuk, Sri; Suriansih, Suriansih; Nurhayati, Etiek
Jurnal Laboratorium Khatulistiwa Vol 7, No 2 (2024): Mei 2024
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v7i2.1391

Abstract

Facial soap used to clean the face from exposure to dust, pollution, dirt, reduce sebum on the face and eradicate bacteria that can cause acne. Star fruit leaves are efficacious in healing several diseases, such as purulent skin inflammation, boils and medicine for gout. Phytochemical of star fruit leaves contain alkaloid, flavonoid, saponin, tannin and steroid compounds that can inhibit bacterial growth. This study aims to determine the effect of liquid facial soap containing of star fruit leaf extract (Averrhoa bilimbi L) on the growth of Staphylococcus aureus bacteria by diffusion method.This study used a Quasi Experiment research design. The population in this study were wuluh star fruit leaves. The sample used is star fruit leaf extract which is made into liquid facial soap preparations with concentrations of 5%, 10%, 15% and 20%. This antibacterial testing method uses the Kirby-Bauer diffusion method. The results of antibacterial research obtained the average diameter of the inhibition zone at 5% concentration of 10.60 mm, 10% concentration of 11.20 mm, 15% concentration of 12.10 mm, and 20% concentration of 13.23 mm. Based on the diameter of the inhibition zone formed at concentration of 5% is categorized as a moderate response and at concentration of 10%, 15% and 20% is categorized as a strong response.The results of simple linear regression statistical analysis obtained p value = 0.000 < α 0.05 which means Ha is accepted, which means that there is a significant effect on the preparation liquid facial soap ethanol extract of star fruit leaves (Averrhoa bilimbi L) against the growth of Staphylococcus aureus diffusion method.
UJI AKTIVITAS TROMBOLITIK EKSTRAK ETANOL RIMPANG TEMULAWAK SECARA IN VITRO Hardini, Khaulani Refsi; Nurhayati, Etiek; Wahdaniah, Wahdaniah
Jurnal Laboratorium Khatulistiwa Vol 3, No 1 (2019): November 2019
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v3i1.930

Abstract

          Temulawak dikenal oleh masyarakat Indonesia sebagai tanaman obat berkhasiat.Temulawak ampuh mengatasi penyakit kuning,diare,maag,menurunkan lemak darah,mencegah pengumpalan darah,dan sebagai antioksidan.ekstrak rimpang temulawak mengandung senyawa berupa flavonoid,akoid,tanin.triterpenoid,saponin,dan glikosida.flavonoid berperan atas trombolitik dengan cara meningkatkan kandungan activator plasminogen jaringan dan mengurangi plasminogen activator inhibitor.         Penelitian ini bertujuan untuk mengetahui perbedaan aktivitas ekstrak rimpang temulawak yang di bandingkan dengan nattokinase terhadap presentase bekuan lisis.        Penelitian ini merupakan penelitian eksperimental semu yakni secara ini vitro menggunakan metode yang dikembangkan oleh prased et al.(2017) dan dimodifikasi oleh kawsar et al., (2011). Penelitian ini menggunakan teknik purposive sampling dengan sampel ekstrak rimpang temulawak yang dibuat melalui metode maserasi pelarut etanol pada konsentrasi 0,1, 0,2, dan 0,3 % yang dilakukan pengulangan sebanyak 9 kali.aktivitas trombolitik ditentukan dengan menghitung presentase bekuan lisis dari sampel darah.         Hasil uji univariat aktivitas trombolitik paling tinggi adalah pada konsentrasi 0,3% yaitu sebesar 42.19%. kemudian dari hasil uji statistik regresi linear menunjukan nilai signifiknasi p value =0.000 < a  0,05 yang artinya H diterima sehingga dinyatakan ada aktivitas trombolitik ekstrak etanol rimpang temulak secara invitro.Aktivitas ttrombolitak ekstrak etanol rimpang temulawak yang diperoleh sebesar 95,9%. Hal ini menunjukan bahwa rimpang temulawak memiliki potensi sebagai agen trombolitik. 
UJI EFEKTIVITAS KOMBINASI PERASAN BUAH LABU AIR DAN JAHE MERAH SEBAGAI ANTIBAKTERI Salmonella typhi Djohan, Herlinda; Triana, Linda; Nurhayati, Etiek
Jurnal Laboratorium Khatulistiwa Vol 8, No 1 (2024): November 2024
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v8i1.1584

Abstract

Typhoid fever is an acute disease caused by the bacteria Salmonella typhi. This bacteria is usually found in contaminated water or food. Apart from that, this bacteria can also be transmitted from infected people. The treatment carried out is using modern drugs such as the antibiotic chloramphenicol. However, the use of modern medicine has several disadvantages such as side effects. On the other hand, the use of natural ingredients as natural medicine has been widely used. One of them is that water gourd is empirically used as a fever reducer. Water gourd contains secondary metabolites, namely saponins, steroids and phenols which have been proven to have antibacterial activity and are able to inhibit the growth of Salmonella typhi bacteria. Another natural ingredient that has antibacterial activity is red ginger. Red ginger contains active compounds that have antibacterial effects such as flavonoids, phenols, treponoids and essential oils. Antibacterial activity was obtained by measuring the diameter of the inhibition zone after administering 4 variations of the concentration of the juice sample. The positive control used amoxicillin 30 µg/disk and the negative control used distilled water. The research design used was a quasi-experimental method. The samples were water gourd and red ginger juice with varying concentrations of 40%, 60%, 80% and 100% and the average inhibition zone values were obtained, namely 8.875 mm, 9.875 mm, 11.25 mm and 14.25 mm. Based on the results of research and computerized data processing using the Kruskall Walis test, a value of p = 0.000 (p<0.05) was obtained, which means that there is an effect of the concentration of pumpkin juice and red ginger on the inhibitory power of Salmonella thypi bacteria.
Analisis Tekanan Darah pada Penderita Diabetes Melitus di Puskesmas Jungkat, Kalimantan Barat Nurhayati, Etiek; Yustiana Putri, Naimatul Jannah; Slamet, Slamet
Jurnal Laboratorium Khatulistiwa Vol 8, No 1 (2024): November 2024
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v8i1.1682

Abstract

Diabetes mellitus is a chronic disease, the pancreas does not produce enough insulin, or when the body cannot use insulin effectively. Diabetes mellitus can be followed by various complications, including increased blood pressure or hypertension. Diabetes mellitus is one of the diseases with the 5th highest number of patients at the Jungkat Community Health Center. This study aims to analyze blood pressure in diabetes mellitus patients at the Jungkat Community Health Center, Mempawah Regency, West Kalimantan. This research method is a cross-sectional study. The respondents in this study were diabetes mellitus patients who received treatment at the Jungkat Community Health Center, using an incidental sampling technique.  Research on 40 respondents showed the results: the average systolic blood pressure was 158.03 mmHg, and the average diastolic blood pressure was 87.92 mmHg, while the average blood glucose level was 289.83 mg/dl. The results of statistical analysis using the Chi Square correlation test showed that the p-value (0.001) was smaller than α (0.05). The results of statistical analysis show that there is a relationship between blood pressure and blood glucose levels in diabetes mellitus patients at the Jungkat Community Health Center, Mempawah Regency, West Kalimantan.
PERBEDAAN HASIL HITUNG BERBAGAI JENIS LEUKOSIT PADA PASIEN COVID-19 YANG ISOLASI MANDIRI DENGAN ISOLASI DI RSUD KABUPATEN MELAWI Reza, Nur; Santoso, Edi; Nuswantoro, Ari; Indrawati, Ratih; Nurhayati, Etiek; Aditia, Aditia
Media Penelitian dan Pengembangan Kesehatan Vol. 32 No. 3 (2022): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v32i3.1886

Abstract

COVID-19 infection causes various clinical manifestations so the treatment method is also different for each individual. Patient isolation is one of the treatments to break the chain of transmission of COVID-19. Asymptomatic to moderate symptomatic patients are usually asked to self-isolate, while those with severe and critical symptoms are isolated in hospital. Leukocyte examination is an important parameter and plays a role in determining patient follow-up. The aim of this study was to find out whether there were differences in leukocyte differential-counts in COVID-19 patients who were self-isolating and those isolated at Melawi Regional Hospital. This study had a cross-sectional design by taking data from medical records of COVID-19 patients at Melawi Regional Hospital during October 2021 to July 2022. The data taken were from 399 COVID-19 patients, consisting of 182 patients are self-isolating and 217 patients are isolating at Melawi Regional Hospital. In self-isolated patients, the average value of leukocyte count was 7.04 x 10³ cells/µL, and the leukocyte differential-counts was neutrophils 58.45%, lymphocytes 21.81%, monocytes 13.84%, eosinophils 1.52%, and basophils 4.38%. In isolated patients at Melawi Regional Hospital, the average value of leukocyte count was 9.89 x 10³ cells/µL, and the leukocyte differential-counts was neutrophils 75.09%, lymphocytes 12.97%, monocytes 8.38%, eosinophils 0.46%, and basophils 3.11%. The Mann-Whitney U test obtained a significance value of 0.000 (p < 0.05), which means there is a significant difference in the results of leukocyte counts between self-isolated patients and those isolated at Melawi Regional Hospital.
Gambaran Kadar Glukosa Darah Puasa Pada Lanjut Usia (Lansia) di Puskesmas Kota Pontianak Agustriana, Fadhila; Nurhayati, Etiek; Salim, Maulidiyah; Djohan, Herlinda
Jurnal Laboratorium Khatulistiwa Vol 8, No 2 (2025): Mei 2025
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v8i2.1890

Abstract

Lanjut usia (lansia) merupakan kelompok usia ≥60 tahun yang rentan mengalami berbagai masalah kesehatan, salah satunya adalah gangguan metabolisme glukosa yang dapat berujung pada diabetes melitus. Kadar glukosa darah yang tidak terkontrol dapat meningkatkan risiko komplikasi kronis dan memperburuk kualitas hidup lansia. Penelitian ini bertujuan untuk menggambarkan kadar glukosa darah puasa (GDP) pada lansia yang berkunjung ke Puskesmas Perumnas II Sungai Beliung, Kota Pontianak periode Januari-Desember 2024. Penelitian ini menggunakan desain deskriptif dengan pendekatan cross-sectional. Sampel berjumlah 561 orang lansia yang dipilih menggunakan teknik purposive sampling dengan kriteria inklusi lansia yang melakukan pemeriksaan GDP di Puskesmas Perumnas II, sedangkan kriteria ekslusinya adalah lansia yang melakukan pemeriksaan glukosa darah sewaktu di Puskesmas Perumnas II. Hasil penelitian menunjukkan bahwa dari 561 lansia yang melakukan pemeriksaan GDP terdapat 379 (67,56%) lansia yang memiliki kadar GDP ≥126 dan hanya ada 182 (32,44%) lansia yang memiliki kadar GDP <126. Kurangnya aktivitas fisik, usia lanjut dan pola makan tinggi karbohidrat adalah faktor-faktor yang berkontribusi terhadap peningkatan kadar glukosa darah. Penelitian ini merekomendasikan perlunya edukasi berkelanjutan dan pemantauan rutin kadar glukosa darah puasa pada lansia di tingkat pelayanan primer guna mencegah komplikasi yang lebih lanjut.
Co-Authors Aditia, Aditia Agustriana, Fadhila Ari Nuswantoro Dj, Herlinda Djohan Djohan, Herlinda Edi Santoso Hardini, Khaulani Refsi Indrawati, Ratih Laila Kamilla Lestari, cik Verra Budi Linda Triana Maulidiyah Salim Musaidah, Siti Rahmawati, Eri Ratika, Meila Reza, Nur Salim, Maulidyah Shodiq, Ja'far Slamet . Sukma, Sherin Aulia Suriansih, Suriansih Sutriswanto, Sutriswanto Tumpuk, Sri Wahdaniah Wahyudi Yustiana Putri, Naimatul Jannah