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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) WARTA MPI (Media Pharmaceutica Indonesiana) Adi Widya : Jurnal Pengabdian Masyarakat Pharmasipha Intan Husada : Jurnal Ilmiah Keperawatan Jurnal Farmasi dan Sains Indonesia (JFSI) Kunir: Jurnal Farmasi Indonesia (KJFI) Ekspresi: Publikasi Kegiatan Pengabdian Indonesia
Puspitasari, Ismi
Program Studi Farmasi, Fakultas Farmasi, Universitas Setia Budi Surakarta
Religion Arts Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Anti-Acne Activity of Robusta Green Coffee Bean Extract against Cutibacterium acnes Putri, Cinthiya Ekwinta; Puspitasari, Ismi; Novita, Mega; Marlina, Dian
MPI (Media Pharmaceutica Indonesiana) Vol. 7 No. 2 (2025): DECEMBER
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24123/mpi.v7i2.7857

Abstract

Acne vulgaris, a common chronic skin disorder, is primarily caused by the overgrowth of Cutibacterium acnes and often treated with synthetic agents that may cause side effects and resistance. The increasing demand for therapeutics with improved safety profiles and natural alternatives has encouraged the exploration of herbal remedies, including robusta green coffee beans (Coffea canephora). This study aimed to evaluate the anti-acne activity of robusta coffee bean ethanol extract against C. acnes. The extract was prepared through maceration and subsequently evaluated using to phytochemical screening, thin layer chromatography, and in vivo testing on New Zealand rabbits. Results confirmed the presence of flavonoids, alkaloids, tannins, steroids, and triterpenoids. In vivo assays demonstrated that the 75% extract concentration achieved a 96.69% reduction of acne lesions, comparable to the positive control at 99.35%, while lower concentrations showed moderate activity. These findings highlight the potential of robusta coffee bean extract as a promising natural anti-acne agent. The study implies that robusta extract can be further developed into herbal-based dermatological formulations, although future research should focus on isolating active compounds and conducting clinical trials for broader application.
Edukasi Beyond Used Date (BUD) Obat di Kelurahan Gagak Sipat, Ngemplak, Boyolali Fitri Kurniasari; Jena Hayu Widyasti; Ismi Puspitasari; Carolina Eka Waty
Ekspresi : Publikasi Kegiatan Pengabdian Indonesia Vol. 3 No. 1 (2026): Januari: Ekspresi : Publikasi Kegiatan Pengabdian Indonesia
Publisher : Asosiasi Seni Desain dan Komunikasi Visual Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ekspresi.v3i1.1063

Abstract

Community service with the theme of Expired Date (ED) and Beyond Use Date (BUD) aims to improve knowledge and understanding of proper medication storage as an effort to enhance the health of the Gagak Sipat community. Knowledge about medication usage limits and checking product expiration dates educates the public to be more cautious and to avoid health risks that may arise from consuming products that have exceeded their usage period or have expired. The use of medicines beyond their ED and BUD indicates that the drugs may have experienced reduced stability related to storage conditions. Decreased stability of pharmaceutical preparations can affect their physical quality, which in turn impacts the effectiveness and safety of the medication. The educational method used in this program included lectures accompanied by the distribution of leaflets, followed by practical simulations on checking ED and calculating BUD for various dosage forms. The results of this educational activity showed that community members were able to determine the ED and BUD for several pharmaceutical preparations such as tablets, powders, capsules, syrups, eye drops, ear drops, and others. The community in Gagak Sipat village gained an understanding of the risks associated with using medications beyond the BUD, including reduced effectiveness, the risk of microbial contamination, and potentially harmful chemical reactions. It was emphasized that some medications that are expired or used beyond their BUD can pose more serious health risks, especially when used to treat severe diseases.
Co-Authors Adrianto, Madyo Ana Indrayati Carolina Eka Waty Dewi Arum Sari Dwi A, Santi Ghani Nurfiana Fadma Sari Gunawan Pamudji Widodo Hayu W, Jena Ismi Rahmawati Kurniasari, Fitri Madyo Adrianto Marlina, Dian Mega Novita Meta Kartika Untari Meta Kartika Untari Nuraini Harmastuti Patricia Alfayu Velix Putri, Cinthiya Ekwinta Sari Astuti Sari Astuti Suhartinah Vina Desti Ashari Waty, Carolina Eka Wiwin Herdwiani