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Journal : Biota

Microscopic Characterization of Keji Beling Extract (Strobilanthes crispus L.) As Herbal Medicine Studies Pramita Laksitarahmi Isrianto; Sonny Kristianto; Sukian Wilujeng
Biota Vol 7 No 2 (2021): Jurnal Biota 2021
Publisher : Faculty of Science and Technology Universitas Islam Negeri Raden Fatah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19109/Biota.v7i2.8382

Abstract

Keji Beling (Strobilanthes crispus L.) is one of medicinal plants in Acanthaceae family. The leaves are the part that is often used as the herbal products such as; herbs, tea and the others. This study aims to determine the characteristics of the functional groups of organic compounds, mineral content and antioxidant activity in the leaf extract of Strobilanthes crispus L. using pottery. Test analysis in research using FTIR, SEM-EDX, XRF. The result of showed the presence of CH alkenes, CH aromatic, C-O alcohol/ether/carboxylic acid/ester, C-N amine, NO2 Nitro compounds, O-H hydrogen bond alcohol /phenol and N-H amines/amides The mineral composition contained macro elements of Ca, K, P and S. While the identified micro minerals are Si, Fe, Mo, Sr, Mn, Ba, Cu, Zn, and Ni. The microscopic morphology of Strobilanthes crispus L. leaf extract is in the form of porous solid particels, thus it is to have high water solubility. The results of the antioxidant test using the DPPH method obtained an IC50 value of 19.20 ppm which is included in the group of very active antioxidants
senyawa aktif pada famili zingiberaceae sebagai anti inflamasi: studi insiliko Cycloxygenese-2 ) COX2) Sonny Kristianto; Pramita Laksitarahmi Isrianto; Marmi Marmi; Dina Chamidah; Atta Ullah Khan
Biota Vol 8 No 2 (2022): Jurnal Biota 2022
Publisher : Faculty of Science and Technology Universitas Islam Negeri Raden Fatah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19109/Biota.v8i2.11734

Abstract

Traditional medicine employs many ingredients that have been used for generations for treatment and are based on society's norms. These ingredients are referred to as jamu. The research aim was to determine the types and uses of medicinal plants, the active compound content, and the potential of traditional herbal medicine as a fever-lowering bio-computation. The traditional herbal formula was determined using a direct interview method combined with a purposive sampling technique in this study. We used the software for phytochemical screening and molecular docking. COX-2 was used to analyse proteins, and six ligands were used: Quercetin, Curcuminoid, Zingerone, Heyneanone, Zerumbone, and Sabinene. This study discovered 22 different types of medicinal plants in Bangselok village, East Java, Indonesia. The Zingiberaceae family is frequently used as an ingredient in herbal medicine. Ginger, Lempuyang, Bangle, Temu Mangga, Temu Putih, and Temu Giring contain flavonoid compounds. The docking results showed that Quercetin, Zingerone, Heyneanone, Zerumbone, and Sabinene ligands were attached to domain A by the control of natural COX-2 ligands, namely NAG and EDO, predicting that they could be used as an anti-inflammatory and the combination of active compounds recommended as herbal medicine.