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Studi Literatur : Aktivitas Antibakteri Daun Binahong (Anredera cordifolia) terhadap Staphylococcus aureus Damayanti, Sevira Putri; Mariani, Ria; Nuari, Doni Anshar
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 9 No. 1 (2022): Februari
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v9i1.3367

Staphylococcus aureus merupakan bakteri yang dapat menyebabkan infeksi. Pengobatan infeksi biasanya menggunakan antibiotik, namun ditemukan masalah dalam penggunaan antibiotik salah satunya resistensi antibiotik. Binahong (Anredera cordifolia) dapat dijadikan sebagai alternative pengobatan antibakteri. Tujuan artikel review ini adalah untuk mereview ekstrak daun binahong yang dapat berpotensi menghambat pertumbuhan bakteri Staphylococcus aureus termasuk didalamnya menggali informasi mengenai konsentrasi yang memberikan zona hambat terhadap pertumbuhan Staphylococcus aureus dan golongan senyawa yang bertanggungjawab terhadap aktivitas antibakteri Staphylococcus aureus. Hasil uji antibakteri terhadap ekstrak daun binahong (Anredera cordifolia) dapat menghambat pertumbuhan bakteri Staphylococcus aureus dengan metode difusi pada konsentrasi 10%, 15%, 20% dengan diameter zona hambat 1,7 mm, 2,0 mm, 2,6 mm, sedangkan pada metode dilusi pada konsentrasi 25%. Pada fraksinasi daun binahong (Anredera cordifolia) dapat menghambat pertumbuhan Staphyloccus aureus (MIC 512 µg/ml). Hal ini dapat dikatakan bahwa ekstrak daun binahong (Anredera cordifolia) berpotensi dapat menghambat pertumbuhan bakteri Staphylococcus aureus. Golongan senyawa yang terkandung dalam ekstrak daun binahong (Anredera cordifolia) diduga adanya senyawa alkaloid, steroid, flavonoid dan fenol yang dapat menghambat pertumbuhan bakteri Staphylococcus aureus.

Review: Antioxidant Activity Of Indonesian Banana Peels Mariani, Ria; Noviyanti, Noviyanti; Inayah, Rahifa; Wibowo, Diki Prayugo
Jurnal Ners Vol. 9 No. 4 (2025): OKTOBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i4.50701

Pisang merupakan buah yang paling banyak dikonsumsi di dunia dan memiliki berbagai manfaat kesehatan. Kulit pisang, yang sering dianggap sebagai limbah, ternyata mengandung senyawa bioaktif dengan aktivitas antioksidan yang signifikan. Aktivitas antioksidan dari kulit pisang telah banyak dilaporkan, termasuk kulit pisang dari Indonesia. Review ini membahas aktivitas antioksidan kulit pisang Indonesia serta kandungan senyawa aktif di dalamnya. Sejumlah penelitian menunjukkan bahwa terdapat ekstrak kulit pisang dari Indonesia yang memiliki aktivitas antioksidan sangat kuat, antara lain ekstrak kulit pisang Ambon mentah, kulit pisang Barangan mentah, dan kulit pisang Muli. Penelitian juga menunjukkan bahwa kulit pisang yang masih mentah memiliki aktivitas antioksidan yang lebih tinggi dibandingkan dengan yang sudah matang, yang disebabkan oleh kandungan flavonoid dan tanin yang lebih tinggi. Potensi antioksidan dari kulit pisang terutama disebabkan oleh keberadaan flavonoid, saponin dan tanin yang berperan penting dalam menetralkan radikal bebas.

Cross-Cultural Analysis of the Role of Traditional Medicine in Health Access in Indonesia Abdullah, Vera Iriani; Wahidin, Wahidin; Wibowo, Diki Prayugo; Mariani, Ria
West Science Interdisciplinary Studies Vol. 1 No. 10 (2023): West Science Interdisciplinary Studies
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/wsis.v1i10.279

This study investigates the contribution of traditional medicine on health care access in Indonesia through a quantitative cross-cultural approach. Utilizing a sample of 350 individuals that is diverse in terms of age, gender, and ethnic background, the study investigates the prevalence and characteristics that impact the use of traditional medicine. The findings show that traditional healing methods are heavily relied upon, especially by elderly people and members of specific ethnic groups. The necessity for culturally responsive healthcare practices is highlighted by the discovery that cultural beliefs are important determinants of health-seeking behaviour. The results add to the growing body of knowledge about the integration of traditional medicine into modern healthcare systems by highlighting the significance of customizing therapies to the many cultural settings found throughout Indonesia.

Analyzing Knowledge Networks in Health Care through Collaborative Research Exploration Wibowo, Diki Prayugo; Mariani, Ria; Aldo, Novian; Andarmoyo, Sulistyo
West Science Interdisciplinary Studies Vol. 1 No. 10 (2023): West Science Interdisciplinary Studies
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/wsis.v1i10.293

The exploration of collaborative research in healthcare is a dynamic and multifaceted endeavor, as evidenced by analysis of influential articles, citation patterns, and keyword frequencies. Davenport and Prusak's seminal work on knowledge management serves as a foundational foundation, emphasizing the critical role of effective knowledge utilization and sharing in collaborative healthcare research. This research explores linkages with other influential articles, including Scott's examination of social network analysis, Star and Griesemer's insights on institutional ecology, and Tranfield et al.'s methodology on evidence-based knowledge management. Further analysis extends to works on thematic analysis, inter-organizational collaboration, cancer genomics, and qualitative research methods, all of which contribute to a rich tapestry of collaborative healthcare research. Keyword analysis revealed thematic priorities, with a major focus on "Care" and "Experience", emphasizing the human dimension of healthcare. Challenges, technology and organizational aspects emerged as prominent themes, reflecting a holistic approach to collaborative exploration. The interplay between keywords such as "Dynamic", "Mechanisms", and "Performance" underscores the evolving nature of collaborative efforts and the need for strategic mechanisms to address challenges and improve performance. The analysis also highlights contemporary concerns, including the impact of the COVID-19 pandemic, barriers to collaboration, and the intersection of mental health and social media.

Cross-Cultural Analysis of the Role of Traditional Medicine in Health Access in Indonesia Abdullah, Vera Iriani; Wahidin, Wahidin; Wibowo, Diki Prayugo; Mariani, Ria
West Science Interdisciplinary Studies Vol. 1 No. 10 (2023): West Science Interdisciplinary Studies
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/wsis.v1i10.279

This study investigates the contribution of traditional medicine on health care access in Indonesia through a quantitative cross-cultural approach. Utilizing a sample of 350 individuals that is diverse in terms of age, gender, and ethnic background, the study investigates the prevalence and characteristics that impact the use of traditional medicine. The findings show that traditional healing methods are heavily relied upon, especially by elderly people and members of specific ethnic groups. The necessity for culturally responsive healthcare practices is highlighted by the discovery that cultural beliefs are important determinants of health-seeking behaviour. The results add to the growing body of knowledge about the integration of traditional medicine into modern healthcare systems by highlighting the significance of customizing therapies to the many cultural settings found throughout Indonesia.

Analyzing Knowledge Networks in Health Care through Collaborative Research Exploration Wibowo, Diki Prayugo; Mariani, Ria; Aldo, Novian; Andarmoyo, Sulistyo
West Science Interdisciplinary Studies Vol. 1 No. 10 (2023): West Science Interdisciplinary Studies
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/wsis.v1i10.293

The exploration of collaborative research in healthcare is a dynamic and multifaceted endeavor, as evidenced by analysis of influential articles, citation patterns, and keyword frequencies. Davenport and Prusak's seminal work on knowledge management serves as a foundational foundation, emphasizing the critical role of effective knowledge utilization and sharing in collaborative healthcare research. This research explores linkages with other influential articles, including Scott's examination of social network analysis, Star and Griesemer's insights on institutional ecology, and Tranfield et al.'s methodology on evidence-based knowledge management. Further analysis extends to works on thematic analysis, inter-organizational collaboration, cancer genomics, and qualitative research methods, all of which contribute to a rich tapestry of collaborative healthcare research. Keyword analysis revealed thematic priorities, with a major focus on "Care" and "Experience", emphasizing the human dimension of healthcare. Challenges, technology and organizational aspects emerged as prominent themes, reflecting a holistic approach to collaborative exploration. The interplay between keywords such as "Dynamic", "Mechanisms", and "Performance" underscores the evolving nature of collaborative efforts and the need for strategic mechanisms to address challenges and improve performance. The analysis also highlights contemporary concerns, including the impact of the COVID-19 pandemic, barriers to collaboration, and the intersection of mental health and social media.

Phytochemical screening and antioxidant activity of Brasicca oleracea vegetables from Cikajang, Garut Mariani, Ria; Rizkio Syamsudin, R. Aldizal Mahendra; Sumarni, Neneng; Wibowo, Diki P
Science Midwifery Vol 11 No 5 (2023): December
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v11i5.1368

Antioxidants from dietary plants have been thought to be good for human health. Brassica oleracea vegetables are potential antioxidant vegetables. Cikajang is one of the vegetable-producing centers in West Java, located in Garut district. Vegetables cultivated in the Cikajang area include cabbage, cauliflower, and keciwis, which are species of Brassica oleracea. There is no research regarding the phytochemistry and antioxidant activity of Brassica oleracea vegetables collected in Cikajang. Behalf of that, this research aims to determine the phytochemical screening and antioxidant activity of cabbage, cauliflower, and keciwis from Cikajang. The phytochemical screening was carried out using several identification reagents, while the antioxidant activity test was carried out using the DPPH (2,2 diphenyl-1-picrylhidrazyl) method. The results of phytochemical screening show that in the dry powder and extract of cabbage, flavonoids, phenols, and steroids/triterpenoids were identified. In the dry powder and extract of cauliflower, flavonoids, saponins, phenols, and steroid/triterpenoids were identified. In the dry powder and extract of keciwis, flavonoids, saponins, gallic tannins, and phenols were identified. The results of the antioxidant activity test using DPPH show that vitamin C as a standard had an IC50 value of 5.223 µg/ml, while the IC50 values of cabbage, cauliflower, and keciwis extracts were 39.948, 35.199, and 15.032 µg/ml, respectively.

Literature review: The utilization of tomatoes (Solanum lycopersicum) and lidah buaya (Aloe vera) in cosmetic applications Wibowo, Diki Prayugo; Rahma, Siti; Herawati, Irma Erika; Mariani, Ria
Science Midwifery Vol 11 No 5 (2023): December
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v11i5.1375

The popularity of herbal cosmetics has been growing due to their effectiveness and ability to reduce the adverse effects associated with the use of synthetic goods. Plants contain phytochemicals like alkaloids, flavonoids, saponins, sterols, triterpenoids, and tannins, which give them many health benefits, such as antioxidant activity, anti-inflammatory effects, UV protection, skin regeneration, depigmentation, anti-dandruff properties, and more. Plants like tomatoes and Aloe vera contain phytochemicals that can be used in cosmetics. We want to give you all the information you need about how tomatoes and Aloe vera might be used in cosmetics. This includes what chemicals they contain, how they work biologically, and how to make cosmetics with them. This article review employs online literature studies as its methodology. The research data comprises articles sourced from reputable journal platforms, including Google Scholar, PubMed, Science Direct, and Research Gate. These articles were selected from publications spanning the period from 2013 to 2023. The research that has already been done supports the idea that both tomatoes and Aloe vera contain many chemicals that could be used in cosmetic treatments.

Review: Antibacterial activity of lime (Citrus aurantifolia L.) peel Wibowo, Diki Prayugo; Mariani, Ria
Science Midwifery Vol 12 No 1 (2024): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v12i1.1475

Over the past three decades, a plethora of scientific publications have indicated that medicinal plants may offer a viable substitute for antibiotics. Research on the antibacterial activity of lime peel, or Citrus aurantifolia L., has been widely published. This review aimed to highlight the lime peel as antibacterial agents. Numerous scientific papers included for this review demonstrated the potentially effective antibacterial properties of lime peel. Strong antibacterial activity is exhibited by lime peel essential oils, extracts, and fractions. One component of lime peel essential oils that contributes to its antibacterial properties is limonene. According to this study, infections brought on some bacteria including cariogenic bacteria and acne bacteria can be treated using lime peel.

Studi Perbandingan : Penapisan Fitokimia Serta Aktivitas Antioksidan Daun dan Batang Ketepeng Cina (Senna Alata (L.) Roxb) Wibowo, Diki Prayugo; Mariani, Ria; Yusuf, Aldy Fadlillah
Jurnal Ners Vol. 8 No. 1 (2024): APRIL 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v8i1.20082

Antioksidan sangat penting dalam kehidupan kita karena antioksidan dapat menetralkan radikal bebas sehingga dapat mencegah penuaan dini dan penyakit degeneratif. Salah satu tumbuhan obat yang memiliki aktivitas antioksidan adalah ketepeng cina atau Senna alata. Ekstrak daun ketepeng Cina memiliki aktivitas antioskidan lebih kuat daripada ekstrak bunga dan polong. Pada ekstrak daun juga telah berhasil diisolasi senyawa flavonoid yang memiliki aktivitas antioksidan yang kuat. Berdasarkan penapisan fitokimia, daun ketepeng cina teridentifikasi senyawa glikosida, tanin, flavonoid, antrakuinon, saponin dan triterpenoid/steroid. Sedangkan pada bunga teridentifikasi senyawa flavonoid, fenolik, saponin dan tanin. Penelitian mengenai identifikasi fitokimia pada batang ketepeng cina serta uji membandingkan aktivitas antioksidan daun dan batang ketepeng cina belum ada. Untuk itu penelitian ini bertujuan untuk membandingkan penapisan fitokimia, aktivitas antioksidan daun dan batang ketepeng cina. Penapisan fitokimia dilakukan dengan menggunakan beberapa perekasi identifikasi sedangkan uji aktivitas antioksidan menggunakan metode DPPH (2,2 difenil-1-pikrilhidrazil). Berdasarkan hasil penapisan fitokimia daun ketepeng cina teridentifikasi senyawa alkaloid, flavonoid, tanin, kuinon, saponin dan steroid/triterpenoid. Sedangkan pada batang ketepeng cina teridentifikasi alkaloid, flavonoid, kuinon, saponin dan triterpenoid/steroid. Berdasarkan hasil uji aktivitas antioksidan dengan DPPH, IC50 ekstrak daun ketepeng cina adalah 18,524 µg/ml dan IC50 ekstrak batang adalah 26,437 µg/ml. Aktivitas antioksidan ekstrak daun dan batang ketepeng cina dikategorikan antioksidan sangat kuat.

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