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All Journal Folia Medica Indonesiana Jurnal NERS The Indonesian Journal of Public Health Perspektif : Kajian Masalah Hukum dan Pembangunan Majalah Obstetri dan Ginekologi Health Notions Molecular and Cellular Biomedical Sciences (MCBS) Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Biomolecular and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL Jurnal Abdi Masyarakat Indonesia

Ernawati Ernawati

Deparment Of Obstetrics And Gynecology, Faculty Of Medicine, Universitas Airlangga, Dr Soetomo Hospital, Surabaya

Author-ID : 3195754

Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Maternal and perinatal outcomes of pre-referral magnesium sulfate treatment in severe preeclampsia patients Rizki Amalia Sari; Sulistiawati Sulistiawati; Ernawati Ernawati
Majalah Obstetri dan Ginekologi Vol. 30 No. 1 (2022): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V30I12022.17-23

HIGHLIGHTS 1. Consumption of magnesium sulfate is recommended for prevention against eclampsia. 2. Magnesium sulfate administration to preeclamptic mothers is effective in reducing the risk of eclampsia.3. Pre-referral magnesium sulfate administration and maternal and perinatal outcomes in severe preeclampsia patients was analyzed.4. Magnesium sulfate did reduce eclampsia risk, but not ICU and NICU care rates, maternal mortality, perinatal asphyxia, and perinatal mortality. ABSTRACT Objectives: This study analyzed the association between pre- referral magnesium sulfate administration and maternal and perinatal outcomes in severe preeclampsia patients. Materials and Methods: This was a retrospective observational analytic study using cross-sectional design. Samples were 132 pregnant women with preeclampsia referred to dr. Saiful Anwar, Hospital Malang, Indonesia in 2019. Data were taken from the patients’ medical records. Maternal outcomes measured in this study were the incidence of eclampsia, ICU care, and maternal mortality, while the perinatal outcomes included the incidence of asphyxia, NICU care, and perinatal mortality. Results: Patients’ history of magnesium sulphate administration significantly associated with the incidence of eclampsia with p-value 0.035 and odds ratio (OR) 2.413, thus consumption of magnesium sulphate could reduce the risk of seizures. However, it did not associate with either maternal ICU care outcomes (p-value 0.087, OR 2.028), or maternal mortality (p-value 0.573). No relationship was found neither between history of magnesium sulphate administration in pregnant women with severe preeclampsia and perinatal outcomes nor with the incidence of asphyxia (p-value 0. 577, OR 0.795), with NICU treatment (p-value 0.205, OR 0.579), and with perinatal mortality (p-value 0.153, OR 3.259). Conclusion: Magnesium sulfate reduced the risk of eclampsia, yet it did not affect either the rate of ICU care, maternal mortality, incidence rate of perinatal asphyxia, the rate of NICU care, or perinatal mortality.

Analysis of Sociodemographic and Information Factors on Family Behaviour in Early Detection of High-Risk Pregnancy Ika Mardiyanti; Shrimarti Rukmini Devy; Ernawati Ernawati
Jurnal Ners Vol. 14 No. 2 (2019): OCTOBER 2019
Publisher : Universitas Airlangga

Introduction: Pregnancy and childbirth are physiological processes experienced by women, but they sometimes have risky conditions. There are still many pregnant women and their families who are unable to detect a high-risk of pregnancy early. This study aims to determine family behaviour in conducting early detection of a high-risk of pregnancy in terms of sociodemographic and information factors.Methods: This study uses an explanatory survey design with a cross sectional design. The sample size of this study was 146, with simple random sampling. The independent variables were sociodemographic factors (age, gender, ethnicity, education, income and religion) and information factors (experience, and media exposure) while the dependent variable is family behaviour. The instrument with the questionnaire used the Likert scale. The data was analysed using partial least square.Results: The results showed that Structural Equation Modelling-Partial least square (SEM-PLS) statistical analysis, through Confirmatory Factor Analysis (CFA), obtained sociodemographic factors on family behaviour of 1,999, and information factors on family behaviour of 13,78. The value of the influence of sociodemographic factors (0.102) and the value of the influence of information factors (0.754). R2 (0.63) and Q2 value of 0.65.Conclusion: Sociodemographic factors and information factors significantly influenced family behaviour factors in early detection of high-risk of pregnancy. Information factors have a greater effect on family behaviour than sociodemographic factors. Midwives as health service providers at the health care centre need to optimize family empowerment through health information efforts in health promotion efforts. Further research requires the involvement of other factors to improve family behaviour, especially in the ability of families to detect early high-risk pregnancies.

The Effect of Antenatal Corticosteroid Therapy to Respiratory Distress Syndrome Event on Preterm Infants in Surabaya Devy Putri Zenita; Martono Tri Utomo; Ernawati Darmawan
Biomolecular and Health Science Journal Vol. 1 No. 1 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

ABSTARCTIntroductions: One of the most common cause of morbidity and mortality in premature infants is respiratory distress syndrome (RDS). Several studies have shown that a single dose administration of antenatal corticosteroid therapy in women who are at high risk for premature delivery was associated with decreased incidence of RDS. The study aims to determine the effect of antenatal corticosteroid therapy on the incidence of RDS in prematurity in the Department of Child Health Hospital Dr. Soetomo.Methods: Analytic observational case-control design study was used for this research. Samples were taken from the medical records of RDS patients in premature baby and non-RDS with 36 samples in each group.Results: Antenatal corticosteroid therapy has effect in RDS incidence (p = 0.016). While the results of the odds ratio was 0.298 (with 95% CI 0.110 to 0.810), it means that premature infants with antenatal corticosteroid therapy has 0.298 times lower risk than those who were not given antenatal corticosteroid therapy.Conclusion: Antenatal corticosteroid therapy did not provide a direct relathionship to the incidence of respiratory distress syndrome in premature infants, but it a protective factor that can reduce the incidence of RDS in prematurity.

Correlation between Maternal Infection and Infant Cholestasis Liofelita Christi Adhi Mulia; I Gusti Made Reza Gunadi Ranuh; Ernawati Ernawati
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 12 No. 1 (2021): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V12I12021.38-41

Introduction: Infant cholestasis has been associated to viral infection. Cytomegalovirus in the pathogenesis of neonatal hepatitis has been already known and it is one of the possible etiological of biliary atresia. The aim of this study was to outline the correlation between maternal infection and infant cholestasis (aged 0-1 year old) in Department of Pediatrics Dr. Soetomo General Hospital, Surabaya. Methods: A case-control study of pregnant women who gave birth in Dr. Soetomo General Hospital from June 2016 to June 2017. The data were taken from medical records. The cases were defined as pregnant women with babies who had cholestasis, and the control was pregnant women who gave birth to a baby without cholestasis within the age of 0-1 year old. Sample cases in this study were drawn from the total population, with the inclusion criteria babies who had cholestasis, and exclusion criteria that include complications of pregnancy and a history of infant’s parent with genetic disorders. The control variable studied was maternal infection history and sex. Samples were taken by purposive control. The data were obtained then summarized and analyzed by univariate and bivariate, using the chi-square table analysis. Results: The number of cases that met the inclusion criteria were 68 patients, and the amount of control taken was 110 patients. The total number of patients studied was 178 patients. Univariate analysis found the cholestasis was more common in mother with infection during pregnancy (73.53% from the total of cholestasis). Bivariate analyzes found relationship between pregnancy infection and cholestasis (p = <0.001, or = 20.726). Conclusion:The maternal infection is significantly associated with cholestasis in infants.

Plasma Level of Umbilical Cord Hemeoxygenase-1 (HO-1) and Neonatal Outcome in Early Onset and Late Onset Severe Preeclampsia Muhammad Ilham Aldika Akbar; Indah Mayang Sari; Ernawati Ernawati; Aditiawarman Aditiawarman
Molecular and Cellular Biomedical Sciences Vol 3, No 1 (2019)
Publisher : Cell and BioPharmaceutical Institute

Background: Many studies had discovered that early onset severe preeclampsia (EO-PE) has worst maternal and neonatal outcome compared to late-onset type (LO-PE), related to its placental involvement. Severe preeclampsia was defined as newly onset severe hypertension developed after 20 weeks gestation in previously normal blood pressure women, with coexistence of proteinuria, or maternal organ or uteroplacental dysfunction. Hemeoxygenase-1 (HO-1) is an enzyme with multiple effect which is protective to pregnancy.Materials and Methods: The total study subjects were 40 pregnant women consisted of 10 EO-PE, 10 normal early onset pregnancy (EO-NP), 10 LO-PE, and 10 normal late onset pregnancy (LO-NP). As much as 5 cc of plasma from umbilical cord was taken as soon as the baby was born, and the HO-1 level was examined by enzyme-linked immunosorbent assay (ELISA). The primary outcome were umbilical cord HO-1 level and neonatal composite morbidity (low Apgar score, low birthweight, length of stay >5 day, respiratory distress syndrome, jaundice and neonatal death).Results: The plasma level of HO-1 in EO-PE subjects were lower than EO-NP (0.96±0.37 ng/mL vs. 2.43±0.58 ng/mL, p<0.001). There were no significant differences in the level of HO-1 in LO-PE and LO-NP (2.18±1.07 ng/mL vs. 3.02±0.64 ng/mL, p=0.277). Plasma level of umbilical cord HO-1 of EO-PE patients was lower compared to LO-PE (0.96±0.37 ng/mL vs. 2.18±1.07 ng/mL, p=0.034). Neonatal outcome of EO-PE was worse than EO-NP (p=0.033), and LO-PE (p=0.003), while in LO-PE did not different with LO-NP (p=0.211).Conclusion: EO-PE is associated with lower plasma umbilical cord level of HO-1 and worse neonatal outcome compared to LO-PE. This indicating abnormal placental blood vessel development, placental ischemia in EO-PE, lead to reduced uteroplacental perfusion and significantly worse neonatal outcome compared to LO-PE.Keywords: severe preeclampsia, early onset preeclampsia, late onset preeclampsia, hemeoxygenase-1

PERAN MAP, ROT, IMT DALAM SKRINING PREEKLAMPSIA DI INDONESIA Dwi Putri Rahayu Tampubolon; Lilik Herawati; Ernawati Ernawati
Indonesian Midwifery and Health Sciences Journal Vol. 3 No. 4 (2019): Indonesian Midwifery and Health Sciences Journal, October 2019
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v3i4.2019.331-340

Abstrak Latar Belakang : Preeklampsia tetap menempati peringkat pertama sebagai penyebab tingginya Angka Kematian Ibu (AKI) di Surabaya dari tahun 2013-2017 sebesar 28.92 %. Tingginya angka preeklampsia bisa dicegah dengan dilakukannya skrining preeklampsia yang mudah dilakukan pada trimester I dan II yaitu dengan dilakukannya skrining Mean Arterial Presure (MAP), Roll Over Test (ROT), Indeks Masa Tubuh (IMT) di fasilitas kesehatan dasar. Tujuan dari penelitian ini untuk mengetahui hubungan antara Skrining Preeklampsia (MAP, ROT, IMT) yang dilakukan pada ibu hamil trimester I dan trimester II serta kejadian preeklampsia. Metode : Penelitian ini adalah penelitian Retrospektif, Case Control dengan sampel pada kelompok kasus yaitu pasien preeklampsia pada saat trimester I dan II yang dilakukan skrining preeklampsia sedangkan untuk kelompok kontrol, ibu hamil normal yang juga dilakukan skrining preeklampsia pada trimester I dan II. Hasil : Didapatkan besar sampel 189 ibu hamil dengan preeklampsia selama 1 tahun, pengambilan sampel dengan teknik consecutive sampling. Hasil pemeriksaan diperoleh pada kelompok kasus didapatkan pasien dengan MAP (+), ROT (+), IMT (+) berturut-turut adalah 43 (95.6 %), 18 (40 %) dan 18 (40 %), sedangkan pada kelompok kontrol diperoleh hasil 18 (40 %) sampel MAP (+), 26 (57.8 %) ROT (+), 5 (11.1 %) IMT (+). Hasil uji statistik Chi Square menunjukan adanya hubungan signifikan antara skrining MAP dan IMT dengan kejadian preeklampsia dengan nilai p berturut-turut (p 0.0001, OR = 32.250 dan p 0.002, OR = 5.333 ), namun tidak didapatkan hubungan antara skrining ROT dengan kejadian preeklampsia (p 0.092 OR = 0.487). Didapatkan hubungan ketiga skrining (MAP, ROT, IMT) dengan kejadian preeklampsia (p 0.001, OR 4.529). Kesimpulan : Pasien MAP (+) dan IMT (+) mempunyai resiko sebesar 32 kali dan 5 kali pada preeklampsia. Skrining ROT (+) tidak mempunyai hubungan dengan kejadian preeklampsia.AbstractBackground: Preeclampsia still ranks first as the cause of the high Maternal Mortality Rate (MMR) in Surabaya from 2013-2017 at 28.92%. The high rate of preeclampsia can be prevented by conducting pre-eclampsia screening that is easy to do in the first and second trimesters by doing Mean Arterial Presure (MAP) screening, Roll Over Test (ROT), Body Mass Index (BMI) in basic health facilities. The purpose of this study was to determine the relationship between Preeclampsia Screening (MAP, ROT, BMI) performed in first trimester and second trimester pregnant women and the incidence of preeclampsia. Methods : This study was a retrospective study, case control with samples in the case group, namely preeclampsia patients during the first and second trimesters of preeclampsia screening, while for the control group, normal pregnant women who were also screened for preeclampsia in the first and second trimester. Results There was a sample of 189 pregnant women with preeclampsia for 1 year, taking samples by consecutive sampling technique. The results of the examination were obtained in the case group obtained patients with MAP (+), ROT (+), BMI (+) respectively 43 (95.6%), 18 (40%) and 18 (40%), while in the control group obtained results of 18 (40%) samples of MAP (+), 26 (57.8%) ROT (+), 5 (11.1%) BMI (+). The Chi Square statistical test results showed a significant relationship between MAP and BMI screening with the incidence of preeclampsia with p values in a row (p 0.0001, OR = 32,250 and p 0.002, OR = 5,333), but no association between ROT screening and the incidence of preeclampsia ( p 0.092 OR = 0.487). Obtained the third screening relationship (MAP, ROT, BMI) with the incidence of preeclampsia (p 0.001, OR 4,529). Conclusion: MAP (+) and BMI (+) patients have 32 times and 5 times higher risk of preeclampsia. Screening for ROT (+) has no relationship with the incidence of preeclampsia.

RISK FACTORS OF PREECLAMPSIA WITH SEVERE FEATURES AND ITS COMPLICATIONS Eka Suci Wulandari; Ernawati Ernawati; Djohar Nuswantoro
Indonesian Midwifery and Health Sciences Journal Vol. 5 No. 1 (2021): Indonesian Midwifery and Health Sciences Journal, January 2021
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v5i1.2021.29-37

Abstract.Background : The maternal mortality rate in Indonesia is dominated by preeclampsia as the second highest cause after bleeding. Several predictors can be categorized as risk factors that can be used to increase alertness in the care of pregnant women with severe preeclampsia to avoid complications. The purpose of this study was to study the relationship between risk factors for severe preeclampsia and its complications. Methods: This study used an observational analytic method with a case control design. The sampling technique is simple random sampling. The number of samples in this study were 80 samples, with 40 samples in each group. The case group was severe preeclampsia with one complication and the control group was severe preeclampsia without complications. Statistical analysis used was chi square and multiple logistic regression analysis. Results: The results showed that there was a significant relationship between age variables (p value = 0.001 < 0.05; OR = 5.318; CI = 2.118 – 13,356), BMI (p value = 0.002 < 0.05; OR = 6.000; CI = 1.958 – 18.384 ) and gestational age (p value = 0.039 < 0.05; OR = 2.636; CI = 1.040 – 6.685). Multiple logistic regression analysis showed that BMI (p = 0.003), age (p = 0.001) and gestational age (p = 0.048) were variables included in the final modeling of the regression analysis with the incidence of severe preeclampsia complications. Conclusion: BMI is the variable that has the strongest relationship with the incidence of severe preeclampsia complications.

THE RELATIONSHIP OF SOCIAL SUPPORT WITH THE DEGREE OF NAUSEA AND VOMITING IN PREGNANCY Cempaka Yudithia Junandar; Ivon Diah Wittiarika; Budi Utomo; Ernawati Ernawati
Indonesian Midwifery and Health Sciences Journal Vol. 4 No. 1 (2020): Indonesian Midwifery and Health Sciences Journal, January 2020
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v4i1.2020.26-32

Abstract Background : At the beginning of a pregnancy the mother experiences various processes of transition or adaptation regarding changes in herself, so that she really needs support from her environment. Lack of social support can worsen the physiological complaints of pregnant women including Nausea and Vomiting in Pregnancy (NVP). Complaints of nausea and vomiting can affect the mother in carrying out daily activities, affect the mother's social situation with the environment and cause stress. Therefore, it is important to research the relationship between social support and the degree of nausea and vomiting in first and second-trimester pregnant women. Method : This research method is observational analytic with cross sectional research design. Sampling used the total sampling method with the criteria of pregnant women who had complaints of nausea and vomiting. Collecting data using primary data using a 24-hour PUQE questionnaire that measures the duration and frequency of nausea and vomiting and the MSPSS questionnaire measuring social support. The data collected were analyzed using the Spearman test (p<0.15). Results : Out of 47 respondents, 34 pregnant women (72.3%) received high social support. Besides that, 24 out of 47 respondents (51.1%) experienced moderate degree of NVP. In this study, there were no respondents who experienced severe degree of NVP. Spearman test analysis results obtained p= 0.833 or p>0.15. Conclusion : There is no relationship between social support with NVP in first and second trimester of pregnancy.

THE RELATIONSHIP BETWEEN MENSTRUAL CYCLE CHARACTERISTICS WITH DYSMENORRHEA AND ADOLESCENTS SOCIAL LIFE Raissa Manika Purwaningtias; Dwiyanti Puspitasari; Ernawati Ernawati
Indonesian Midwifery and Health Sciences Journal Vol. 4 No. 3 (2020): Indonesian Midwifery and Health Sciences Journal, July 2020
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v4i3.2020.280-294

ABSTRACTBackground: Dysmenorrhea is a common gynecological problem related to the menstrual cycle. Risk factors for dysmenorrhea are age of menarche, length of menstrual cycle, duration and menstrual volume. Teenagers who experienced dysmenorrhea report the negative impact of dysmenorrhea on a social life. This study aimed to determine the relationship between menstrual cycle characteristics with dysmenorrhea and adolescent social life. Method: The study design used in this research was Cross Sectional with statistical analysis of Rank Spearman test and Chi Square and a significance limit of 5%. The population in this study were 449 students with the inclusion criteria of female students aged 14-16 who had menstruated in the last 3 months. Data was collected using primary data. Sample of 151 students were obtained using total sampling techniques. Results: The percentage of respondents who experienced dysmenorrhea in this study were 90.7% and 78.8% of them stated that dysmenorrhea disrupted their social life. There was a relationship between duration (p=0.006) and menstrual volume (p=0.004) with dysmenorrhea. The relationship also found between menstrual volume (p=0.033) and dysmenorrhea (p=<0.001) with adolescent social life. Conclusion: The characteristics of the menstrual cycle that were associated with dysmenorrhea were duration and menstrual volume and the social life of adolescents were significantly correlated with dysmenorrhea.

MATERNAL FACTORS ON LABOR WITH CESAREAN SECTION HISTORY Qonita Hanifah; Linda Dewanti; Ernawati Ernawati
Indonesian Midwifery and Health Sciences Journal Vol. 4 No. 4 (2020): Indonesian Midwifery and Health Sciences Journal, October 2020
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v4i4.2020.325-331

AbstractBackground : Cesarean section without medical indications can have negativity in developing or developed countries. Cesarean section is a medical intervention in certain circumstance but must be recognized as a major surgical procedure with potential risks to the mother and baby. This research aim to analyze maternal factors in labor with a history of cesarean esction. Method : this research was a cross sectional method with collected 72 medical records in RSUD Dr. M. Soewandhie Surabaya. Result : Maternal age, interpregnancy interval, indication of past Cesarean section, and BMI during pregnancy, did not correlate with method of delivery. Factors which correlated to method of delivery after Cesarean section were prior vaginal delivery (p=0,044) and length of stay (p=0,000). Conclusion : There is a relationship between the factors of vaginal birth history and length of stay with delivery method.

Co-Authors Achmad Zam Zam Aghasy Aditiawarman Aditiawarman, Aditiawarman Agus Sulistyono Aldika Akbar, Muhammad Ilham Ario Danianto Armedian Oktaviani Puspaningrum Askandar Tjokroprawiro Atika Atika Ayu Maghfira Nida Putri Budi Utomo Cempaka Yudithia Junandar Devy Putri Zenita Dina Delvin Anggriani Dwi Putri Rahayu Tampubolon Dwiyanti Puspitasari, Dwiyanti Ecccita Raheestyningtyas Eka Suci Wulandari Ernawaty Ernawaty Hafiza Amadhin Rusti HERAWATI, LILIK Hermanto Tri Joewono I Gusti Made Reza Gunadi Ranuh Ika Mardiyanti Indah Mayang Sari Ismoedijanto Ivon Diah Wittiarika Jihan Qonitatillah Jimmy Yanuar Anas Khanisyah Erza Gumilar Khusnul Putri Maharani Laksana, Muhammad Ardian Cahya Linda Dewanti Liofelita Christi Adhi Mulia Made Ayu Suastini Mahrus A Rahman, Mahrus A Martono Tri Utomo Muhammad Adrianes Bachnas Muhammad Arief Adibrata Nabeel Usama Okbah Nareswari Imanadha Cininta Marcianora Netti Herlina Nofita Fachryandini Novi Dwi Ambarsari Nurul Mardiyah Nuswantoro, Djohar Nuzulul Azizah Ramdan Wulandari Okta Margarita Susiana Prillia Tri Suryani PUNGKY MULAWARDHANA, PUNGKY Qonita Hanifah Raissa Manika Purwaningtias Risa Etika, Risa Rizki Amalia Sari Rosalia Adriani Malika Sabrina Kemala Hapsari Shrimarti Rukmini Devy Sjahjenny Mustokoweni, Sjahjenny Sofia Al Farizi Sulistiawati Sulistiawati Taufiq Hidayat Ucik Rochmayanti Wahyul Anis Wahyunnisa Indrarosiana Wardhana, Manggala Pasca Yasyviena Za’ima Elnabila Yemima Sonita Nugraheni

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