Eric Priyo Prasetyo
Department Of Conservative Dentistry, Faculty Of Dental Medicine, Universitas Airlangga

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Bone formation and mineralization around the implant in osteoporotic animal models enhanced by mesenchymal stem cells Hendrijantini, Nike; Kuntjoro, Mefina; Agustono, Bambang; Ari, Muhammad Dimas Aditya; Kurdi, Abil; Mundiratri, Karina; Prasetyo, Eric Priyo; Hong, Guang
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 2 (2024): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i2.p91-96

Abstract

Background: Poor bone quality, sometimes caused by osteoporosis, can lead to dental implant failure. Human umbilical cord mesenchymal stem cells (hUCMSCs) can differentiate into osteoblasts and offer an alternative therapy for poor bone conditions. Purpose: This study aims to evaluate the effect of hUCMSCs induction on the extent of osseointegration by the new bone formation area of dental implants in osteoporotic animal models. Methods: The samples were divided into two groups, i.e., control and induced hUCMSCs groups at different times. An ovariectomy was performed to assess the osteoporosis condition. The control group was injected using gelatin, and the treatment group was administered hUCMSCs. Terminations were conducted at 2 and 4 weeks, respectively. The collected samples were then subjected to histological examination to analyze new bone formation and its proportion. In addition, alkaline phosphatase staining was also performed to evaluate the mineralization area. The data was analyzed using the one-way analysis of variance (ANOVA). Results: Both for new bone formation area as well as the proportion of new bone, it was observed that the best results were in the group with induction of hUCMSCs at 2 weeks. Alkaline phosphatase staining also confirmed that the highest mineralization was observed in the same group. Conclusion: hUCMSCs induced new bone formation in the implant placement in osteoporotic animal models.
The inhibitory activity of Avicennia marina leaf extract on Enterococcus faecalis as a root canal irrigation material Prabanita, Amellindha Salsabilah; Soesilo, Diana; Sularsih; Dwi Andriani; Kuntjoro, Mefina; Prasetyo, Eric Priyo
Conservative Dentistry Journal Vol. 15 No. 2 (2025): July-December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v15i2.2025.57-61

Abstract

Background: Enterococcus faecalis is considered the most common cause of root canal failure and persistent infection. The standard irrigation solution is 5.25% NaOCl which has drawbacks, such as causing inflammation in the periapical area. New antibacterial agents from natural materials with similar antibacterial properties to chemicals have been developed. Avicennia marina contains flavonoids, saponins, tannins, and avicequinone, which can inhibit bacterial metabolism. Objective: to determine the effect of Avicennia marina leaf extract with various concentrations on the antibacterial inhibitory power of Enterococcus faecalis as a root canal irrigation material. Materials and Methods: The samples were divided into six groups: K+ (5.25% NaOCl), K- (distilled water), P1 (7.5%), P2 (12.5%), P3 (17.5%), and P4 (22.5%). The leaves of Avicennia marina were extracted using ethanol maceration with a rotary evaporator to obtain a concentrated extract, which was then diluted with distilled water to the desired concentrations. The antibacterial effect was tested using the disk diffusion method by applying 0.01 ml of each test sample to sterile paper disks with a sterile micropipette. Results: Inhibition zones were observed as follows: K+ (21.67 mm), P1 (0 mm), P2 (10.50 mm), P3 (13.50 mm), and P4 (14.50 mm). Mann Whitney tests showed significant differences (p < 0.05) between K+ and P1, P2, P3 and P4, as well as between P3 and P4. Conclusion: Avicennia marina leaf extract had antibacterial effects against Enterococcus faecalis at concentrations of 12.5%, 17.5%, and 22.5%.
Antibacterial and antibiofilm activities of plant extracts against fusobacterium nucleatum Juniarti, Devi Eka; Prasetyo, Eric Priyo; Tiara Anandita; Firdaus, Marsa Amalia; Swastika, Tesalonika Devanaya; Irma; Dayanti, Marisa Elvi; Ramadhan, Daniyal Lazuardi
Conservative Dentistry Journal Vol. 15 No. 2 (2025): July-December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v15i2.2025.105-108

Abstract

Background: The pathogenicity of Fusobacterium nucleatum is more acknowledged these days. In the oral cavity, this bacterium plays a massive role in caries formation and periodontal problems such as periodontitis. The use of plant extract as an antibacterial or antibiofilm agent has grown in favor recently. Plant-derived extracts are said to be less toxic and to have comparable efficacy as their predecessors. Purpose: The goal of this article review is to provide an overview of the different bioactive substances found in plant extracts that are effective against Fusobacterium nucleatum. Review: In total 10 journals that fit the inclusion and exclusion criteria were chosen, with a total of 14 different plant extracts reviewed. MIC of the various extracts was found, where extract of lemongrass, purple leaf, Eucalyptus galbie, mulberry, and mangosteen was found at various concentrations. Conclusion: Each bioactive compound found on plant extracts holds their own mechanism in order to provide antibacterial behavior.
ORAL HEALTH IN RESIDENTS OF THE PUSKESMAS PEGIRIAN AREA: A STRUCTURAL EQUATION MODELING APPROACH Dian Agustin Wahjuningrum; Devi Eka Juniarti; Tamara Yuanita; Setyabudi Setyabudi; Eric Priyo Prasetyo; Galih Sampoerno
Abdi Dosen : Jurnal Pengabdian Pada Masyarakat Vol. 10 No. 2 (2026): JUNI
Publisher : LPPM Univ. Ibn Khaldun Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/abdidos.v10i2.3475

Abstract

Oral and dental health remain major public health concerns because they significantly influence quality of life and general well-being. Although community members often demonstrate adequate knowledge and positive attitudes toward oral health, these factors do not always translate into appropriate preventive behaviors. This study aimed to analyze the structural relationship between knowledge, attitude, and oral health practices among residents in the Puskesmas Pegirian area using Structural Equation Modeling (SEM). A cross-sectional analytic study was conducted involving 250 adult participants selected through purposive sampling. Data were collected using a validated Knowledge, Attitude, and Practice (KAP) questionnaire related to oral health. Data analysis was performed using Partial Least Squares Structural Equation Modeling (PLS-SEM) to evaluate both measurement and structural models. The results demonstrated that knowledge significantly influenced attitude (β = 0.61; p < 0.001), while attitude significantly influenced oral health practice (β = 0.54; p < 0.001). Knowledge also showed a direct but weaker effect on practice (β = 0.21; p < 0.05). Attitude acted as a significant mediating variable between knowledge and oral health behavior. These findings indicate that improving knowledge alone is insufficient to promote sustainable oral health behavior without strengthening positive attitudes. Therefore, oral health promotion programs at the primary health care level should integrate behavioral reinforcement and motivational strategies to achieve long-term behavioral change.
Co-Authors Almira, Amanila Hena Ambarwati, Venny Lusanda Anandita, Tiara Ananta Tantri Budi Bambang Agustono Bin Sharizal, Shafy Shariz Bin Zainal Abidin, Imran Cecilia G. J. lunardhi Cecilia Gerda Juliani Lunardhi Chang, Nicole Ava Charles, William Christabel, Phebe Fedora Cornelia Melinda Adi Santoso Dayanti, Marisa Elvi Devi Eka Juniarti Dian Agustin Wahjuningrum Diana Soesilo, Diana Dwi Andriani Dyanita Hasri Evelyn Tjendronegoro Evelyn Tjendronegoro Fadiyan Amriel, Menza Faidah, Faidah Firdaus, Marsa Amalia Firmansyah, Awang Bagus Fitriana, Astila Galih Sampoerno Guang Hong, Guang Gunawan, Nathania Elita Handoko, Jessica Cristy Harry Laksono, Harry Ira Widjiastuti Irma Karina Mundiratri Karlina Samadi Karlina Samadi Karlina Samadi Ketut Suardita, Ketut Kharisna, Deaniddo Kun Ismiyatin Kurdi, Abil Latief Mooduto, Latief Liong, Michelle Mefina Kuntjoro Michael Josef Kridanto Kamadjaja Muhammad Dimas Aditya Ari Nabila, Rizka Affan Natan, Daniel Nike Hendrijantini Ohara, Masaru Paidal, Nurfahira Prabanita, Amellindha Salsabilah Prasetyaningtias, Silvia Arlita Hayu Radixtio Auzan Fepiosandi Ramadhan, Daniyal Lazuardi Ranggi Hardian Nugro Astuti Riyadi, Tiara Lathifah Rizka Firdaus Rosidin Santiaji, Daradhasih Bestari Saptaningrum, Mardikaning Riasta Saravanan, Pravinna Setyabudi Setyabudi Setyabudi Shariz Bin Sharizal, Shafy Sholeh Ardjanggi Singgih Harseno Sukandar, Wilson Sukaton, Sukaton Sularsih Swastika, Tesalonika Devanaya Syahria, Hania Dana Tamara Yuanita Tania, Cindy Grace Tiara Anandita Tjendronegoro, Evelyn Ulfadi , Bakhiitah Thufailah Putri Widya Saraswati Wijanarko, Christina Immee Zora, Zofia