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SEXUAL BEHAVIOR AND KNOWLEDGE LEVEL OF COMMERCIAL SEX WORKERS INFLUENCE THE SPREAD OF SEXUALLY TRANSMITTED INFECTIONS Rochman Mujayanto; Erdianto Setya Wardhana
ODONTO : Dental Journal Vol 6, No 2 (2019): December 2019
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.6.2.107-112

Abstract

Background : Sexually transmitted infections (STIs) are commonly found in commercial sex workers (CSWs) due to lack of knowledge and bad behavior in sexual intercourse. STI does not only cause symptoms in the genital area but also lesions in the oral cavity. Method : This research was an analytical survey with cross sectional approach. Samples were 110 CSWs selected by simple random sampling. Chi-Square test was used to see the difference in the influence of the level of knowledge and sexual behavior on the incidence of oral cavity lesions. Result: Oral cavity lesions related to STIs were found in 44 cases, including suspect oral candidiasis, ulcers, suspect linear gingival erythematous (LGE), Suspect Kaposi Sarcoma and Oral Hairy Leukoplakia. Lesions were found in 43.9% respondents with low knowledge level and 37.7% in good knowledge level. Chi-Square test obtained p value of 0.328 (p> 0.05) showed that there was no difference between the knowledge level and the occurrence of lesions. Lesions were found 94.1% in respondents with bad sexual behavior and 15.8% in respondents with good sexual behaviour. Chi-Square test obtained p value of 0.00 (p> 0.05) which means that there are significant differences between good sexual behavior respondents and bad sexual behavior respondents towards the presence of lesions. Conclusion: The level of knowledge was not a risk factor for oral lesions, whereas bad sexual behavior was a risk factor for oral cavity lesions.
PENGARUH WAKTU POLISHING DAN ASAM SITRAT TERHADAP MICROLEAKAGE PADA TUMPATAN RESIN KOMPOSIT NANOFILLER AKTIVASI LIGHT EMITING DIODE - In Vitro Dhurohmah .; Rochman Mujayanto; Siti Chumaeroh
ODONTO : Dental Journal Vol 1, No 1 (2014): July 2014
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.1.1.11-15

Abstract

Background: The objective of this research is to investigate influence of polishing time and citric acid on microleakage in nanofiller composite resin restoration (Z350XT,3M). Method: The research was conducted on a class V restoration amount sample 24 on bovine teeth. The first group restoration was polished immediately after curing then was soaked in distilled water. The second group was polished immediately after curing and then was soaked in citric acid.The third group was polished after 24 hours of curing and then was soaked in distilled water. The fourth group was polished after 24 hours of curing then was soaked in citric acid. Samples were immersed for 7 days and then were soaked in methylene blue for 1 day and were split longitudinally and were observed using microskopstereo and were measured using calipers. Result: Data were analized by Kruskal-wallis with the result of p > 0,05, there is a significant difference in group I, II, III, and IV. Mann- Whitney test results the difference between the data. Conclusion: The conclution is there were significant differences between the groups which immersed with citric acid of distilled water and there is no significant difference between groups which polished immediately and polished 24 hours later.
PENGARUH APLIKASI VIRGIN COCONUT OIL TERHADAP PENINGKATAN JUMLAH FIBROBLAS PADA LUKA PASCA PENCABUTAN GIGI PADA RATTUS NOVERGICUS Anggun Hibah Jannah Tamara; Yayun Siti Rochmah; Rochman Mujayanto
ODONTO : Dental Journal Vol 1, No 2 (2014): December 2014
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.1.2.29-34

Abstract

Background: Wound healing is a complex biological process. Fibroblast is one of cell which is responsible for the wound healing process. Virgin Coconut Oil (VCO) have health benefit as antibacterial, antiinflamatory, antioxidant, and immunomodulatory. This research was purposed to know the influence use of VCO over the amount of fibroblast in wound healing after dental extraction.Method: Research quasi experimental with post test control group design and using 15 Rattus novergicus which were divided into three groups (control positive, VCO topical application, and VCO per oral application). Tooth removal was committed by using explorer, scalpel-blade, and arterial clamp. Then VCO applied everyday for 7 days. Day 7th Rattus novergicus were died, the socket after extraction were made into histological form, then the amount of fibroblast were counted with 5 field of views and made in average. Result: The number of fibroblast of the most numerous was VCO per oral ( 48,6 ± 49,8 ), VCO topical ( 36,2 ± 38,8 ), and control positive ( 33,4 ± 35,2 ). The results of the Saphiro Wilk test and Levene test acquired data normally distributed and homogeny, so it continued to One Way Anova and data showed there were significant difference among the groups of samples with value p<0,05.Conclusion: The conclusion of this research is VCO could increase the number of fibroblasts in wound healing after dental extractions
EKSTRAK DAUN SALAM DALAM MENINGKATKAN EKSPRESI FIBROBLAST GROWTH FACTOR PADA ULKUS TRAUMATIK RONGGA MULUT Amrina Rosada; Rochman Mujayanto; Adisty Restu Poetri
ODONTO : Dental Journal Vol 7, No 2 (2020): December 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.7.2.90-96

Abstract

Background: Traumatic ulcers are lesions of the oral mucosa caused by mechanical, chemical, and temperature trauma. Traumatic ulcer treatment aims to reduce inflammation, accelerate the healing process, and reduce pain. Bay leaf has anti-inflammatory pharmacological activities. This study aims to determine the effect of bay leaf extract on the expression of fibroblast growth factor in traumatic ulcer oral mucosa in Wistar rats.Method: This is an experimental research with a post-test only control group design, consisting of four groups with 20 sample of male Wistar rats. All animals were injured using a hot burnisher attached to the labial mucosa for 1 second. The gel was applied twice daily until the 3rd and 5th day after the ulcer has formed. Rat mucosal tissues were analyzed by immunohistochemical staining for FGF expressions. Statistical analysis using SPSS Mann-Whitney test.Result: The results showed the mean of cells expressing FGF in the bay gel extract group on the 3rd and 5th days were 8.4 ± 0.8, and 13.6 ± 0.5. Mann Whitney test results showed P<0.05 there is a significant differential expression of FGF traumatic ulcer oral mucosa of experimental animals on days 3 and 5 compared control group.Conclusion: Bay leaf extract increased FGF expression on days 3 and 5
BAY LEAF (SYZYGIUM POLYANTHUM) EXTRACT EFFECT ON IL-10 EXPRESSION IN ORAL ULCER Arina Shafia; Rochman Mujayanto; Anggun Feranisa
ODONTO : Dental Journal Vol 7, No 1 (2020): July 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.7.1.53-59

Abstract

BAY LEAF (SYZYGIUM POLYANTHUM) EXTRACT GEL EFFECT ON TNF- Α EXPRESSION IN TRAUMATIC ULCERS HEALING PROCESS Annisha Savira; Rochman Mujayanto; Musri Amurwaningsih
ODONTO : Dental Journal Vol 7, No 1 (2020): July 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.7.1.25-30

Abstract

Background: Traumatic ulcers were injuries that occur to the epithelium and basement membrane, due to physical, mechanical, or chemical trauma. The healing process of traumatic ulcers was divided into three main phases, namely inflammatory, proliferation, and maturation phase. TNF-α as a proinflammatory mediator worked 2-3 days which later would be replaced by an anti-inflammatory mediator. This research aimed to determine the impact of bay leaf extract gel, which had a very high anti-inflammatory content, on TNF-α expression in accelerating the ulcers healing process.Method: This research method was an in vivo experimental laboratory research using a post-test only control design. The sample consists of 20 rats divided into four groups, namely, the control group on day 1, control groups on day 3, treatment groups on 1st day, and treatment groups on 3rd day. Rats were made traumatic ulcers on the lower lip mucosa and were given bay leaf extract gel in the morning and evening. The tissue was then made into a histological preparation and given immunohistochemical staining to see TNF-α.Result: The results showed the mean of cells expressing TNF-α in the bay leaf gel extract group on the 1st and 3rd days has P> 0.05. Independent T-test on 1st day dan 3rd group showed a significant difference in TNF-α expression in the control and treatment groups.Conclusion: The conclusion obtained in this study was bay leaf extract gel had a significant effect on the expression of TNF-α in the traumatic ulcers healing process.
Topical application of 1% ZnSO4 on oral ulcers increases the number of macrophages in normal or diabetic conditions of wistar rats Rochman Mujayanto; Kus Harijanti; Iwan Hernawan
Dental Journal (Majalah Kedokteran Gigi) Vol. 49 No. 3 (2016): September 2016
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (186.617 KB) | DOI: 10.20473/j.djmkg.v49.i3.p133-136

Abstract

Background: Therapy for chronic ulcer in diabetic patient is by modifying local inflammation response using drugs that acts as immunomodulator, neuromodulator and growth factors stimulator. Topical zinc is one of drug that can modifiy local inflammation response, immunostimulation or immunosuppresion. Purpose: This study was to prove about the number of macrophage in oral ulcer between normal and diabetes microscopically and the difference if treated by 1% ZnSO4 gel topically. Method: Ulcer in lower labial mucosa was made in normal and diabetic Wistar rats (induced by STZ), then applied 1% ZnSO4 gel and CMC-Na gel as control. They were decapitated in third and fifth day and specimen was made by processing lower labial mucosa Result: Microscopically, the result showed the number of macrophages in oral ulcer in diabetic condition was significantly higher than normal and the application of 1% ZnSO4 increased the number of macrophages in fifth day. Conclusion: The number of macrophages was higher in diabetic than normal condition, and was proven that topical application of 1% ZnSO4 increased the number macrophages of oral ulcer diabetic and normal condition.
Fixed drug eruption pada perioral akibat obat golongan quinoloneFixed drug eruption in the perioral due to quinolone medications Nur Khamilatusy Solekhah; Rochman Mujayanto
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 30, No 3 (2018): Desember
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (612.189 KB) | DOI: 10.24198/jkg.v30i3.18065

Abstract

Pendahuluan: Fixed Drug Eruption (FDE) adalah salah satu diagnosis reaksi hypersensitivitas tipe 4 yang bermanifestasi di kulit berbentuk makula merah kebiruan dan kadang-kadang bula diatasnya, serta muncul ditempat yang sama apabila terpapar obat yang sama. Tujuan laporan kasus ini untuk memberikan informasi mengenai reaksi hypersensitivitas berupa fixed drug eruption pada perioral akibat obat golongan quinolone. Laporan kasus: Pasien mengeluhkan bibir atas sebelah kanan tebal dan berwarna biru keunguan, setelah minum obat levofloxacin (golongan quinolone). Pasien memiliki riwayat beberapa waktu yang lalu pernah mengalami kondisi yang sama dan dilokasi yang sama, setelah minum obat ciprofloxacin (golongan quinolone). Mekanisme fixed drug eruption terjadi karena hapten obat berikatan dengan sel basal keratinosit atau dengan melanosit pada lapisan basal epidermis menyebabkan pelepasan sitokin seperti TNF-α, keratinosit mengekspresikan ICAM-1 yang menarik sel CD8+ yang kemudian bertahan di lokasi lesi. Sel CD8+ memberikan memori fenotip, sehingga ketika paparan obat terulang, respon akan berkembang lebih cepat pada lokasi yang sama. Penatalaksanaan kasus dengan menghentikan penggunaan obat penyebab dihentikan dan pemberian methylprednisolone 4mg selama 10 hari. Lesi pada perioral warnanya memudar, tetapi tidak hilang dan menetap. Simpulan: Pasien fixed drug eruption dapat sembuh dengan menghentikan obat yang diduga sebagai alergen, serta diberikan anti inflamasi kortikosteroid, meskipun Lesi pada perioral warnanya memudar, tetapi tidak hilang dan menetap.Kata kunci : Fixed drug eruption, quinolone, perioral. ABSTRACT            Introduction: Fixed drug eruption (FDE) is one diagnosis of type 4 hypersensitivity reactions manifests on bluish-red macular skin and sometimes with the presence of bullae, and appears at the same place when exposed to the same type of medication. The purpose of this case report was to provide information regarding hypersensitivity reactions in the form of fixed drug eruption (FED) in the perioral due to quinolone medications. Case report: The patient was presented with a chief complaint of the thick and purplish blue right upper lip after taking the levofloxacin (quinolone group drug). Patients had a history of experiencing the same condition and in the same location after taking ciprofloxacin (quinolone group drug) quite some times before. Mechanism of fixed drug eruption occurred because the drug’s hapten was bound to the keratinocytes basal cell or with melanocytes in the epidermis basal layer causing the release of cytokines such as TNF-α. Keratinocytes expressed ICAM-1 that attract CD8+ cells which then persisted at the lesion site. CD8+ cells provided a phenotypic memory so that when drug exposure was repeated, the response at the same location will develop faster. Management of cases was performed by stopping the use of the causative drug and administration of 4 mg of methylprednisolone for 10 days. The perioral lesions colour was faded but had not lost and still maintained. Conclusion: Fixed drug eruption patient was able to recover by stopping the use of the drugs suspected as allergens, and administration of anti-inflammatory corticosteroids, even though the lesions had not lost and still maintained, but the perioral lesions colour was fading.Keywords: Fixed drug eruption, quinolone, perioral.
THE EFFECTIVENESS OF SIWAK (SALVADORA PERSICA) EXTRACT’S KILLING CAPABILITY AGAINST STREPTOCOCCUS VIRIDANS (IN VITRO) Megya Agustina Dentisari; Rochman Mujayanto; Andina Rizkia Putri Kusuma
Jurnal Medali Vol 4, No 2 (2022): Media Dental Intelektual September 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.4.2.157-162

Abstract

Background: Streptococcus viridans is an anaerobic bacteria that cause root canal infection. The irrigation materials that have antibacterial and non-toxic effects greatly support the success of root canal treatment. Sodium hypochlorite must be used with extreme caution because it can irritate the periapical tissue when used at high concentrations and has a pungent odor that interferes with patient comfort. Siwak (Salvadora persica) is a plant with antibacterial components including tannins, alkaloids, and flavonoids. This study aims to determine the effectiveness of siwak (Salvadora persica) extract’s killing capability against Streptococcus viridans (in vitro).Method: This study’s method used a post-test only control group design with experimental laboratory research consisting of 5 groups, including a negative control group (DMSO), a positive control group (sodium hypochlorite), and 3 treatment groups using siwak extract with concentrations of 55%, 60%, and 65%. This study used the maceration and dilution method with 25 samples.Result: The study’s result was analyzed using the Kruskal-Wallis non-parametric statistical test with a significant result of 0.00 (p<0.05)Conclusion: It can be concluded that siwak extract has an effective killing capability against Streptococcus viridans at a concentration of 60%.
ORAL HYGIENE BURUK PASIEN RAWAT INAP TIDAK BERKAITAN DENGAN PERTUMBUHAN ORAL CANDIDIASIS Addina Aimana Sabila; Ade Ismail A.K; Rochman Mujayanto
Odonto : Dental Journal Vol 4, No 1 (2017): July 2017
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (477.084 KB) | DOI: 10.30659/odj.4.1.56-60

Abstract

Background: Nosocomial infections can develop in the oral cavity due to poor oral hygiene. Oral Candidiasis is one of the most frequent nosocomial infection in oral cavity. The objective of this study is to describe the oral hygiene and oral candidiasis in hospitalized patients. Method: This analitical observational study used cross sectional design. Subject of the study were 74 adult patients aged 20-65 who are hospitalized at the Sultan Agung Islamic Hospital Semarang. Oral hygiene assessed from the presence of debris and calculus on the tooth surface using Simplified Oral Hygiene Index (OHIS) that were grouped in three categories (good, moderate, bad). Oral candidiasis diagnosed through clinical examination and swab procedure of suspicious lesions, and identified the presence of its spores and hyphae under a microscope observation. Kendal Tau test is used to analyze the correlation between oral hygiene with oral candidiasis. Results: Results showed patients with oral candidiasis in the poor and moderate oral hygiene were 29.7% and 1.4%, whereas patients without oral candidiasis in the poor and moderate oral hygiene were 60.8% and 8.1%. Kendall Tau correlation test results p value of 0.235 (p> 0.05). Conclusion: Conclusion of this study showed there is no association between oral hygiene with oral candidiasis.