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All Journal Konselor Journal of Maternal and Child Health Martabe : Jurnal Pengabdian Kepada Masyarakat Abdi: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Penelitian Pendidikan, Psikologi Dan Kesehatan (J-P3K) Jurnal Kedokteran Universitas Palangka Raya Jurnal Kedokteran Meditek Perilaku dan Promosi Kesehatan: Indonesian Journal of Health Promotion and Behavior Folia Medica Indonesiana
Arman Yurisaldi Saleh
Universitas Pembangunan Nasional “Veteran” Jakarta
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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The profile of the level of endogenous no in migraine sufferers Saleh, Arman Yurisaldi; Machfoed, Hasan; Kuntoro, Kuntoro
Folia Medica Indonesiana Vol. 52, No. 4
Publisher : Folia Medica Indonesiana

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Migraine is a health problem which had big impact. A neurochemistry change in the dura, that is the increase of the amount of nitrite oxide, originated from an excessive NOS (inducible NOS) activation during ictal. Some researchers assume NO as a main cause of the pain intensity in ictal. Migraine diagnosis is guided by the International Headache Society. Hopefully, this examination can be used as a more objective diagnosis in the future. Methode of this research is descriptive analytic. This study to find the level of endogenous exhaled NO on 91 subject, consisting of 30 normal people, 31 interictal, 30 ictal. An exclusion was done previously. A validation equipment and measurement had been done in accordance with American Thoracic Association guidance. The result is level of endogenous exhaled NO on the normal group (median=5), interictal group (median=11), ictal group (median=14). Coefficient correlation between VAS and level endogenous exhaled NO was 0,815. So, there is an increase of the NO endogen level in the normal people, migraine interictal, and ictal. Strong correlation between intensity of pain (VAS) and level endogenous exhaled NO during ictal.
Vascular Dementia Patients Characteristics With a History of Stroke in a National Brain Center Hospital Jakarta, Indonesia Hanifah, Afifah Kusuma; Astari, Riezky Valentina; Muktamiroh, Hikmah; Saleh, Arman Yurisaldi
Folia Medica Indonesiana Vol. 58, No. 3
Publisher : Folia Medica Indonesiana

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Highlights: • Characteristics of vascular dementia patients with a history of stroke was aimed. • The most characteristics of vascular dementia patients with stroke history are men, post-ischemic stroke, hypertension grade 1, and lesions in the basal ganglia. Abstract: Stroke patients increase each year. Stroke is a cerebrovascular disorder caused by disruption of cerebral blood flow, which could reason vascular lesions within the mind parenchyma to be a threat to significant disorders. One of them is vascular dementia. Each affected person is prone to growing dementia after a stroke in three to five instances. Thisstudy aimed to decide the traits of patients with vascular dementia with a record of stroke. This study used a descriptive retrospective approach with a cross-sectional method. The samples were obtained from the total sampling technique. The sample of the study was vascular dementia patients with a stroke record at the National Brain Center Hospital Prof. Dr. dr. Mahar Mardjono Jakarta in the period of 2020 through the inclusion standards with 191 samples. This study found that the majority of patients were males as many as 129 (67.5%), age group of 55-64 were 67 patients (35.1%), post-ischemic strokes were 164 patients (85.9%), grade 1 hypertension as many as 70 patients (36.6%), and basal ganglia as many as 76 patients (29.23%). Characteristics of vascular dementia patients with the maximum stroke records in men, aged 55-64 years, post-ischemic stroke, grade 1 hypertension, and a majority of the lesions within the basal ganglia.
The Effect of Antinociceptive Flavonoid on Leea Indica Leaves for Orofacial Pain of Adult Zebra Fish (Danio Rerio) Daya, Mei Putra; Saleh, Arman Yurisaldi; Astari, Riezky Valentina
Folia Medica Indonesiana Vol. 57, No. 2
Publisher : Folia Medica Indonesiana

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Pain affects millions of people and is one of the most frequent complaints in the medical office. Pain involves various behavioral and emotional aspects. When it is persistent, it can become debilitating, impairing occupational performance, and producing negative impacts for the economy and public health costs. In general, commercial drugs can improve chronic pain patients' quality of life which can result in adverse reactions. Therefore, the search for new capsules as an opportunity remedy for ache is a challenge. Pain occurs due to stimuli from pain receptors called nociceptors. One pain known in the medical world is orofacial, defined as pain that occurs in soft and hard tissue in the head, face, and neck area. This study determined the antinociceptive effect of flavonoids isolated from the Leea Indica plant, on orofacial pain in zebrafish (Danio rerio) as a test model for behavior or locomotor activity. To study the orofacial pain of zebrafish induced with glutamate, this study was a true experiment. The parameter used was the number of times the fish crossed the line between the caudran from the glass petri dish during 0-5 minutes and 15-30 minutes. The Anova one-way test showed that there were differences in locomotors activity measured from 0-5 minutes and 15-30 minutes by giving flavonoids that could affect zebrafish locomotors activity or an increase in zebrafish locomotors activity. The antinociceptive effect of flavonoids was similar to tramadol. The flavonoids from Leea Indica had an antinociceptive effect on orofacial pain in adult zebrafish. The flavonoid dose of 2.5 mg/ml was a dose that had a significant difference in all treatment groups.
Characteristics of Aphasia in Ischemic Stroke Patients at a National Brain Center in Indonesia Danardhono, Rasya Hapsari; Saleh, Arman Yurisaldi; Theresa, Ria Maria; Astari, Riezky Valentina
Folia Medica Indonesiana Vol. 59, No. 4
Publisher : Folia Medica Indonesiana

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Highlights: 1. This study was the first study identifying the characteristics of aphasia among ischemic stroke patients during COVID-19 pandemic at a national brain center in Indonesia. 2. This study provides additional data for future studies to conduct a comparison between the pre- and post-pandemic incidence of aphasia. Abstract Different types of aphasia may occur due to lesions in various brain regions following ischemic strokes. Global aphasia was the most prevalent type of aphasia before the COVID-19 pandemic. However, stroke incidence and mortality rose during the pandemic. This study aimed to identify the types, clinical and radiological features, and management of aphasia in ischemic stroke cases during the pandemic. This study was a descriptive study with a cross-sectional design. The total sampling technique was used for the sampling process. The research samples were ischemic stroke subjects with aphasia who were diagnosed between January 1 and December 31, 2021, at the National Brain Center Prof. Dr. dr. Mahar Mardjono Hospital, Jakarta, Indonesia. The statistical analysis was performed using IBM SPSS Statistics for Mac, Version 25.0 (IBM Corp., Armonk, N.Y., USA). The results of this study showed that 162 aphasic subjects had suffered from ischemic strokes. The age range of the subjects was 34–87 years old. The majority of the subjects were male (59.9%) and aged 55–65 years (37.0%). The three most common risk factors were hypertension (90.1%), diabetes mellitus (50.0%), and dyslipidemia (75.9%). Motor aphasia (33.3%) and global aphasia (43.8%) were the most prevalent types of aphasia among the subjects. The parietal lobe was the main location of the causative lesions, as demonstrated by 38 global aphasic subjects and 47 motor aphasic subjects. The therapies administered to the subjects consisted of speech therapy (85.2%), antiplatelet therapy (98.1%), anticoagulants (19.1%), recombinant tissue plasminogen activator (rTPA) (1.2%), and neuroprotectors (3.0%). This study concluded that global aphasia was the most common type of aphasia among ischemic stroke patients during the pandemic, with the parietal lobe as the primary location of the causative lesions.
Co-Authors Afifah Kusuma Hanifah Afralia, Aqila Fayza Annisa Azzahra Ramadina Ariyanti Anwar Astari, Riezky Valentina Boenga Nur Cita Danardhono, Rasya Hapsari Dandanah, Maulidya Ayudika Daya, Mei Putra Dewi, Indah Rahma Hanifah, Afifah Kusuma Hany Yusmaini Hasan Machfoed Hermawan, Puthema Alfaridzky Hikmah Muktamiroh Imarta Retri Putri Kristina Simanjuntak Kristina Simanjuntak Kuntoro Kuntoro Luh Eka Purwani Mei Putra Daya Mila Citrawati Mujab, Salwa Tsabitah Althaf Purwaningastuti, Diana Agustini Ramadina, Annisa Azzahra Rasya Hapsari Danardhono Ria Maria Theresa Ria Maria Theresa Riezky Valentina Astari Riezky Valentina Astari Riezky Valentina Astari Riezky Valentina Astari Rusyda Ayusti Anumillah Rusyda Ayusti Anumillah Soroy Lardo Yanti Harjono Hadiwiardjo Yuli Suciati Yuli Suciati