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Efek Antimikroba Ekstrak Lidah Buaya (Aloe vera) Terhadap Isolat Bakteri Penyebab Acne vulgaris Secara Invitro Bahar, Meiskha; Yusmaini, Hany
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 11, No 2 (2017): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Acne vulgaris adalah suatu kondisi inflamasi umum pada unit polisebaseus, ditandai dengan komedo, papul, pustul atau nodul. Penyakit kulit ini bukan merupakan penyakit yang berbahaya tetapi mempunyai dampak yang besar secara fisik maupun psikologik. Prinsip penanganan acne antara lain menurunkan populasi Propionibacterium acne dan menekan inflamasi. Dari penelitian sebelumnya ditemukan adanya mikroorganisme lainnya dalam lesi yang mungkin berperan selain Propionibacterium acne yaitu Staphylococcus aureus, S. epidermidis dan Pityrosporum ovale. Beberapa sumber melaporkan ada beberapa manfaat Aloe vera untuk kecantikan dan perawatan kulit. Aloe vera juga digunakan secara eksternal untuk mengobati berbagai kondisi kulit seperti luka, nyeri dan menekan proses inflamasi. Penelitian ini dilakukan untuk mengetahui efek antimikroba ekstrak Aloe vera konsentrasi 25%,50% dan 75% terhadap isolat bakteri penyebab Acne vulgaris secara invitro dengan menggunakan metode difusi. Sebelum pengujian dilakukan isolasi dan identifikasi bakteri dari lesi. Bakteri yang ditemukan dari lesi penderita tergolong bakteri golongan Gram positif yaitu Staphylococcus aureus dan Propionibacterium acne. Hasil uji One-way Anova menunjukan terdapat perbedaan bermakna efektivitas ekstrak lidah buaya terhadap S.aureus dan P.acne. Uji Post Hoc terhadap S.aureus menunjukan terdapat perbedaan bermakna ELB 25%, 50% dan 75% dengan kontrol (+) dan kontrol (-), tidak terdapat perbedaan bermakna antara ELB 25% dengan 50% dan 50% dengan 75%. Sedangkan antara 25% - 75% berbeda bermakna. Sedangkan Uji Post Hoc terhadap P.acne menunjukan bahwa tidak terdapat perbedaan bermakna antara ELB 25%, 50% dan 75% dengan kontrol positif. Kesimpulan : Ekstrak Lidah Buaya (Aloe vera) mempunyai efek antimikroba terhadap isolat bakteri penyebab Acne vulgaris yaitu Propionibacterium acne dan Staphylococcus aureus pada konsentrasi 25%, 50% dan 75% secara invitro.

HUBUNGAN FAKTOR DEMOGRAFI, PERIODE DAN LAMA KERJA DOKTER TERHADAP KETERLAMBATAN PENGISIAN RESUME MEDIS PASIEN BPJS DI RUANG RAWAT INAP RSAU DR. ESNAWAN ANTARIKSA Nuraini, Nia; K, Gatot Soeryo; Yusmaini, Hany
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 10, No 1 (2016): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

More than 50% of the medical resume at airforce hospital (RSAU) were not returned in due time which caused claim verifcation delayed by social security administrator (BPJS). The purpose of the study was to find out the relation of physician’s demography factors, work periode and duration in terms of the delays in completing medical resume. Cross sectional design was implemented and secondary data was obtained from medical records. Logistic regression analysis showed thedominant factors of the delays in completing medical resume amongstage, sex, work period and work load was sex.

COVID-19 : EDUKASI DAN DESAIN INFOGRAFIS PENGGUNAAN MASKER UNTUK LINDUNGI KAMU DAN AKU Meiskha Bahar; Hany Yusmaini; Erna Harfiani
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 5, No 1 (2021): Desember
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v5i1.5981

ABSTRAKCovid-19 merupakan masalah kesehatan global, belum ada obat yang terbukti efektif mengobati penyakit ini. Penularan Covid-19 terutama terjadi antar manusia, semakin dekat dan semakin lama interaksi maka semakin besar pula resiko penularan yang akan terjadi. Meningkatnya angka kejadian Covid-19 pertengahan tahun ini juga disebabkan oleh varian delta yang tingkat penularannya sangat tingggi dibandingkan dengan varian lainnya. Pemerintah Pusat melalui Kementerian Kesehatan Republik Indonesia pun telah mengeluarkan Surat Edaran Menteri Kesehatan Repubik Indonesia tentang Protokol Pencegahan Penularan virus Covid-19, yang salah satu caranya dengan menggunakan masker bagi masyarakat jika ingin keluar rumah. Hasil studi Centers for Disease Control and Prevention (CDC) menunjukan bahwa menggunakan Dua Lapis Masker efektif menyaring virus Covid-19 sampai dengan 90%. Metode pelaksanaan kegiatan ini adalah melalui pemberian edukasi cara menggunakan masker (double masker) serta pelatihan cara membuat desain infografis mengenai Covid-19 dan penggunaan masker. Kegiatan dilakukan secara daring melalui zoom meeting pada 55 siswa SMA Negeri 1 Tambun Selatan Bekasi. Siswa diberikan pre dan post test pada saat pelaksanaan pelatihan untuk menunjukkan adanya peningkatan pengetahuan setelah pemberian pelatihan. Selain itu juga diadakan perlombaan pembuatan desain infografis yang diikuti oleh beberapa peserta. Dari kegiatan ini diharapkan peserta dapat membantu menyebarkan informasi kepada masyarakat mengenai pentingnya penggunaan masker (double masker) untuk mencegah penularan Covid-19 Kata kunci: covid-19; infografis; masker. ABSTRACTCovid-19 is a global health problem, no drug has been proven effective in treating this disease. Covid-19 transmission mainly occurs between humans, the closer and longer the interaction, the greater the risk of transmission that will occur. The increase in the incidence of Covid-19 in the middle of this year is also caused by delta variants whose transmission rate is very high compared to other variants. The Central Government through the Ministry of Health of the Republic of Indonesia has also issued a Circular Letter of the Minister of Health of The Republic of Indonesia on the Protocol to Prevent Transmission of the Covid-19 virus, which is one way to use masks for the community if they want to leave the house. The results of a Study by the Centers for Disease Control and Prevention (CDC) showed that using two layers of masks effectively filtered the Covid-19 virus up to 90%. The method of implementing this activity is through the provision of education on how to use a mask (double mask) and training on how to create infographic designs about Covid-19 and the use of masks. The activity was conducted online through a zoom meeting on 55 students of State High School 1 Tambun Selatan Bekasi. Students are given pre and post-tests at the time of training to show an increase in knowledge after the training. In addition, there was also an infographic design competition that was attended by several participants. From this activity, it is hoped that participants can help spread information to the public about the importance of using masks (double masks) to prevent the transmission of Covid-19. Keywords: covid-19; infographic; mask.

PERBANDINGAN PENINGKATAN KADAR KALIUM PASIEN LANSIA DENGAN HIPERTENSI YANG DITERAPI ACE-I DAN ARB DI RSUP FATMAWATI PADA TAHUN 2017-2019 Almerveldy Azaria Dohongi; Hany Yusmaini; Erna Harfiani
Jurnal Kedokteran Universitas Palangka Raya Vol 8 No 1 (2020): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Hipertensi merupakan penyakit yang umum terjadi pada lansia akibat berbagai faktor. JNC-8 merekomendasikan beberapa terapi antihipertensi, salah satunya ACE-I dan ARB. Kedua antihipertensi tersebut memiliki efek samping berupa peningkatan kadar kalium, sedangkan lansia rentan terhadap gangguan keseimbangan elektrolit. Penelitian ini dilakukan untuk membandingkan peningkatan kadar kalium pasien lansia yang diterapi ACE-I dan ARB. Penelitian ini bersifat analitik observasional dengan desain cross-sectional. Sampel penelitian adalah data rekam medis yang berjumlah 72 sampel. Pasien yang menggunakan antihipertensi ARB sebesar 39 sampel dan ACE-I sebesar 33 sampel. Penelitian ini dilakukan di RSUP Fatmawati. Teknik pengambilan sampel secara consecutive sampling. Hasil penelitian ini didapatkan kadar kalium pasien lansia dengan hipertensi yang menggunakan antihipertensi ACE-I mengalami kenaikan rata – rata sebesar 0,49 mmol/L dan ARB 0,46 mmol/L dari kadar kalium awal. Hasil uji T tidak berpasangan menunjukkan bahwa tidak terdapat perbedaan yang bermakna antara peningkatan kadar kalium pada lansia (p = 0,716). Kesimpulan yang didapat pada penelitian ini tidak terdapat perbedaan yang bermakna antara peningkatan kadar kalium pasien lansia dengan hipertensi yang diterapi ACE-I dan ARB di RSUP Fatmawati pada Tahun 2017 – 2019

Efek Antimikroba Ekstrak Lidah Buaya (Aloe vera) Terhadap Isolat Bakteri Penyebab Acne vulgaris Secara Invitro Meiskha Bahar; Hany Yusmaini
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 11, No 2 (2017): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Acne vulgaris adalah suatu kondisi inflamasi umum pada unit polisebaseus, ditandai dengan komedo, papul, pustul atau nodul. Penyakit kulit ini bukan merupakan penyakit yang berbahaya tetapi mempunyai dampak yang besar secara fisik maupun psikologik. Prinsip penanganan acne antara lain menurunkan populasi Propionibacterium acne dan menekan inflamasi. Dari penelitian sebelumnya ditemukan adanya mikroorganisme lainnya dalam lesi yang mungkin berperan selain Propionibacterium acne yaitu Staphylococcus aureus, S. epidermidis dan Pityrosporum ovale. Beberapa sumber melaporkan ada beberapa manfaat Aloe vera untuk kecantikan dan perawatan kulit. Aloe vera juga digunakan secara eksternal untuk mengobati berbagai kondisi kulit seperti luka, nyeri dan menekan proses inflamasi. Penelitian ini dilakukan untuk mengetahui efek antimikroba ekstrak Aloe vera konsentrasi 25%,50% dan 75% terhadap isolat bakteri penyebab Acne vulgaris secara invitro dengan menggunakan metode difusi. Sebelum pengujian dilakukan isolasi dan identifikasi bakteri dari lesi. Bakteri yang ditemukan dari lesi penderita tergolong bakteri golongan Gram positif yaitu Staphylococcus aureus dan Propionibacterium acne. Hasil uji One-way Anova menunjukan terdapat perbedaan bermakna efektivitas ekstrak lidah buaya terhadap S.aureus dan P.acne. Uji Post Hoc terhadap S.aureus menunjukan terdapat perbedaan bermakna ELB 25%, 50% dan 75% dengan kontrol (+) dan kontrol (-), tidak terdapat perbedaan bermakna antara ELB 25% dengan 50% dan 50% dengan 75%. Sedangkan antara 25% - 75% berbeda bermakna. Sedangkan Uji Post Hoc terhadap P.acne menunjukan bahwa tidak terdapat perbedaan bermakna antara ELB 25%, 50% dan 75% dengan kontrol positif. Kesimpulan : Ekstrak Lidah Buaya (Aloe vera) mempunyai efek antimikroba terhadap isolat bakteri penyebab Acne vulgaris yaitu Propionibacterium acne dan Staphylococcus aureus pada konsentrasi 25%, 50% dan 75% secara invitro.

Analysis of Cadre Compliance Levels in Running Health Protocol in the Era of Pandemic Covid-19 in Puskesmas Limo Depok Sri Wahyuningsih; Hany Yusmaini; Erna Harfiani; Meiskha Bahar
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2021): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v14i2.2217

Covid-19 outbreak that originated in Wuhan's city is spreading very quickly and is currently a pandemic worldwide. Transmission through droplets that come out of the patient's nose or mouth, whether symptomatic or asymptomatic. Efforts to prevent and fight COVID-19 must be carried out jointly with the community's cooperation and require strong discipline by washing hands frequently, maintaining distance, wearing masks, staying at home, and increasing body power. The purpose of this study was to determine the level of cadre compliance in carrying out health protocols in the era of the Covid-19 pandemic. This research method with a cross-sectional approach. The respondents were cadres of Limo Health Center, Depok. It was total sampling. The research instrument used a questionnaire of Google Form and analyzed using Chi-Square. The results showed that most of the respondents were included in the 46-60 year interval (51.4%) were highly educated, tertiary education (70%), knowledgeable (54.3%), unemployed (87.1), obeyed the protocol. Health (50%). Compliance increases in the elderly, higher education, sufficient knowledge, work status. conclusion there is no relationship between age (p = 0.632), education level (p = 0.794), knowledge level (p = 0.253), work status (p = 0.074) and compliance with the Covid-19 health protocol.

Effectiveness of Metabolite Substance Filtrates of Actinomycetes isolates from Kebun Raya Bogor against the growth of Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi: In Vitro study Muhammad Zaidan Tsani Ariandi; Meiskha Bahar; Hany Yusmaini; Fajriati Zulfa; Cut Fauziah; Andri Pramesyanti
Jurnal Biologi Tropis Vol. 21 No. 1 (2021): Januari - April
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v21i1.2466

Actinomycetes are found in soils with loose, humus, dry characteristics and around plant roots. Actinomycetes produce secondary metabolite compounds as antibacterial. Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi are Gram negative bacteria that can cause infection in humans. This study aims to determine the ability of the Actinomycetes metabolite filtrate from Bogor Botanical Gardens as an antibacterial agent against the growth of E. coli, P.aeruginosa and S. typhi in vitro. This study used an experimental design with samples of Actinomycetes isolats originating from the Bogor Botanical Gardens soil using the disc diffusion method on Muller Hinton Agar (MHA) media by looking at the clear zone of bacterial growth around the disc paper. Of the three concentration groups, namely 50%, 60%, and 70%, the largest average inhibition zone is found at a concentration of 70% with the average for the three test bacteria E. coli, P.aeruginosa and S. typhi respectively: 4.23 mm; 3.0 mm and 8.43 mm. The results of the Kruskal - Wallis test with p value = 0.01 showed that there was an effect of the Actinomycetes metabolite filtrate on the growth of the three tested bacteria as antibacterials.ÃÂ ÃÂ

A Review on the Phytochemical and Pharmacological Activitities of Luffa acutangula (L.) Roxb. Erna Harfiani; Dhigna Citra Pradana; Hany Yusmaini
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 17 No. 02 Desember 2020
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pharmacy.v17i2.8220

Indonesia is a country with a tropical climate, so it can be a place to live for various plants in the world. The use of plants in Indonesia as an alternative treatment requires a lot of research because many plants have not been studied for their chemical compounds and pharmacological effects. Ethnopharmacological studies of a plant can be the basis for medicinal plant research. Empirically, Luffa acutangula (L.) Roxb. (angled luffa, gambas) is a plant that has various therapeutic benefits. This study aimed to determine pharmacognostic properties (macroscopic and microscopic fradments of crude drugs), chemical compound content, and pharmacological activity of L. acutangula extract in literature studies. Literature searching were performed by online searching using Google Scholar, Science Direct, and PubMed as the databases. L. acutangula has been used empirically in Indonesia for helping in the treatment of various diseases. The phytochemical content of L. acutangula extract will affect its pharmacological activity. Phytochemical analysis of L. acutangula leaf powder, namely there are chemical compounds of alkaloids, glycosides, saponins, carbohydrates, amino acids, and lipids. Analysis of the ethanol extract of L. acutangula contained chemical compounds of alkaloids, glycosides, saponins, carbohydrates, and steroids. Analysis of the aqueous extract of L. acutangula contained alkaloids, saponins, carbohydrates, terpenoids, and triterpenoids. The pharmacological activities of L. acutangula included antimicrobial, anticancer, antioxidant, hypoglycemic, hepatoprotective, gastroprotective, immunomodulatory, antiparasitic, anti-inflammatory, analgesic, and anti-thyroid. L. acutangula which contain various phytochemical compounds is potentially to be further studied to develop its pharmacological benefits.

Potensi Daya Hambat Filtrat Zat Metabolit Actinomycetes dari Kebun Raya Bogor terhadap Pertumbuhan Candida albicans dan Malassezia furfur Venita Octavia Tambunan; Meiskha Bahar; Andri Pramono; Cut Fauziah; Hany Yusmaini; Fajriati Zulfa
Bioscientist : Jurnal Ilmiah Biologi Vol 10, No 1 (2022): June
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v10i1.4792

Candida albicans and Malassezia furfur are types of fungi that often cause infections in humans. Widespread fungal infections and lack of therapeutic options can develop fungal resistance and become serious problems in the future. Actinomycetes are Gram-positive bacteria that can produce secondary metabolites such as antifungal, antibacterial, and anticancer. The study aimed to determine the effectiveness of the metabolite filtrate Actinomycetes as an antifungal agent against the in vitro growth of C.albicans and M. furfur. This type of research is a laboratory experimental study with a post-test group design only using metabolite concentrations Actinomycetes of 25%, 50%, 75%, 100%, antifungal testing is done using the agar diffusion method on Sabouraud Dextrose Agar Media. Of the four concentrations, the average diameter of the clear zone for C.albicans is 11.65mm; 12.48mm; 13.63mm and 13.80mm and for M.furfur is 6,025mm; 8,05mm; 9,1mm and 9,9mm. There was a significant difference between each treatment group with a p-value of < 0.05. The compound Metabolite filtrate Actinomycetes derived from Actinomycetes can potentially be antifungal with one of its mechanisms binding to ergosterol in the cell wall that will interfere with the integrity of the fungal cell wall.

Use Of Anti Hypertension And Factors That Affect The Compliance Of Drinking Anti Hypertension In Hypertension Patients In Cisalak Pasar Depok Health Center Meiskha Bahar; Hany Yusmaini; Sri Wahyuningsih
PUINOVAKESMAS Vol. 1 No. 1 (2020): April
Publisher : Pusat Unggulan Iptek (PUI) Poltekkes Kemenkes Yogyakarta

Compliance with treatment is an important factor in the health of hypertensive patients. Compliance is a prerequisite for the effectiveness of hypertension therapy, whereas patient non-compliance with antihypertensive drugs is one of the main factors in the failure of therapy. There are several factors that influence medication adherence and some basic principles of therapy that need to be considered to reach the target of therapy and reduce complications of hypertension. Hypertension sufferers in the Cisalak Pasar Community Health Center are quite numerous, they are generally elementary school and not schooled (74.2%). Kidney complications and a combination of heart and kidney are also quite large, which is 40%. This study aims to determine the pattern of antihypertensive administration and the relationship of age, education level, degree of hypertension, complications and type of therapy with the level of adherence to taking medication for hypertensive patients at the Cisalak Pasar Community Health Center. The research design used in this study was a descriptive cross-sectional. The subjects of the study were essential hypertension patients at the Cisalak Pasar Health Center, Depok who met the inclusion and exclusion criteria. The results of this study are that the pattern of antihypertensive administration is in accordance with JNC 8, there is no relationship between age, education level, hypertension degree and the number of drugs taken with medication compliance, and there is a relationship between the presence or absence of complications with medication compliance

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