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Korelasi antara Kadar Vitamin C Plasma dengan Tekanan Darah pada Lansia di Jakarta Timur Purnamasari, Yuti; Andayani, Diyah Eka; Hardiany, Novi Silvia
Jurnal Ners Vol. 8 No. 1 (2024): APRIL 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v8i1.18580

Abstract

Introduction: The elderly population in developing countries is increasing every year.. In the elderly with increasing age, physiological functions decrease due to degenerative processes, therefore many non- communicable diseases appear in old age. Blood pressure is a parameter used to assess cardiovascular health, which is influenced by oxidative stress. Vitamin C is a strong antioxidant to reduce oxidative stress and maintain endothelial function by producing nitirc oxide. The aim of this study was to analyze the correlation between plasma vitamin C levels and blood pressure in the elderly in East Jakarta.Methods: This study used a Cross-sectional method conducted on 60 elderly members both females and males age > 60 years old in Panti Sosial Tresna Werdha Budi Mulia 1. Vitamin C intake was assessed by semi quantitative food frequency questionnaire, blood pressure was measured by sphygmomanometer and plasma vitamin C levels were detected by spectrophotometer. Analysis correlation between plasma vitamin C level and blood pressure was performed using Spearmen test. Result: This research shows that systolic blood pressure is 125 (90-160) mmHg and diastolic blood pressure is 80 (60-110) mmHg. Median Vitamin C content 0,44 (0,08- 1,81). Results bivariate analysis between plasma vitamin C levels and systolic blood pressure. obtained P>0.05. Conclusion: There was no correlation between plasma vitamin C levels and systolic and diastolic blood pressure.
Freediving, Hypoxia, and Inflammation: Physiological Adaptations and Interactions between HIF and NF-κB Amalina Fakhriah; Novi Silvia Hardiany; Iswanti, Febriana Catur
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 7 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i7.1026

Abstract

Freediving presents a unique set of physiological challenges and adaptations, making it a subject of interest for researchers studying the effects of extreme environmental conditions on the human body. There is a complex interplay between freediving, hypoxia, immune responses, and inflammation, shedding light on the physiological effects of freediving on the human body. This article describes how HIF and NF-κB interact during hypoxia and inflammation, including their synergistic effects and signaling pathways. The regulatory loop involving these transcription factors is highlighted, providing insight into their linked roles in modulating the cellular response to hypoxia and inflammation.