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All Journal Medicina COPING (Community of Publishing in Nursing) E-Jurnal Medika Udayana Jurnal Kesehatan Andalas MNJ (Malang Neurology Journal) Universa Medicina Bali Journal of Anesthesiology Jurnal Penelitian Pertanian Tanaman Pangan Callosum Neurology Journal : Jurnal Berkala Neurologi Bali ISM (Intisari Sains Medis) : Jurnal Kedokteran Majalah Kedokteran Neurosains Kumawula: Jurnal Pengabdian Kepada Masyarakat Bali Anatomy Journal Cermin Dunia Kedokteran Malahayati International Journal of Nursing and Health Science Cermin Dunia Kedokteran
I Made Oka Adnyana
Department Of Neurology, Faculty Of Medicine, Udayana University/Sanglah General Hospital, Bali, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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THE CORRELATION OF SLEEP QUALITY AND SHORT-TERM MEMORY FUNCTION IN MEDICAL STUDENTS Putu Emilia Dewi; I Made Oka Adnyana; Ketut Widyastuti; I Putu Eka Widyadharma
MNJ (Malang Neurology Journal) Vol. 11 No. 1 (2025): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2025.011.01.19

Abstract

Background: Study on the correlation of sleep quality with short-term memory function in medical students has a high urgency considering that intelligence and good memory function are essential for their performance and learning ability in the field. There are only a few related studies on medical students in the Faculty of Medicine and Health Sciences of Universitas Udayana. Objective: This study aims to determine the correlation between sleep quality and short-term memory function of medical students in the Faculty of Medicine and Health Sciences of Universitas Udayana. Methods: The sample was determined by the non-probability consecutive sampling method. The Indonesian version of the Pittsburgh Sleep Quality Index (PSQI) questionnaire and the Digit Span Backwards Task assessed sleep quality and short-term memory function respectively. The data was analyzed by Pearson correlative test and logistic regression multivariate analysis. Results: There were 75 subjects in this study. The PSQI average score of the respondents was 9.35 ± 4.45, and the Digit Span Backwards Task average was 3.75 ± 1.77. The Pearson correlative test showed a moderate correlation between sleep quality and short-term memory function (r = -0.44.; p < 0,05). The logistic regression multivariate analysis found that sleep disturbances affect short-term memory function more than other sleep quality components, with a probability value of 98%. Conclusion: There is a correlation between sleep quality and short-term memory function of medical students in the Faculty of Medicine and Health Sciences of Universitas Udayana.
Tension-type Headache and Migraine as Manifestations of Chronic Post-Traumatic Headache Eric Hartono Tedyanto; -I Made Oka Adnyana; I Putu Eka Widyadharma
Cermin Dunia Kedokteran Vol 50 No 2 (2023): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i2.528

Abstract

Introduction: A subsequent headache within seven days of a head injury (or after regaining consciousness after the head trauma)is referred to as a post-traumatic headache (PTHA); it is referred to as chronic or chronic post-traumatic headache (CPTHA) if it lasts longer than three months after the injury. Case : A 17-year-old male with headache since 3 months ago, 3 days after suffered a blow to his left head from falling from a chair. At that time, the patient fainted for about 15 minutes but had no complaints after regained consciousness. Pain is felt on the left side of the head, throbbing, mild-moderate intensity, and feels heavier with a loud sound or a too-bright light. Discussion: Post-traumatic headache is clinically diagnosed. Laboratory and routine diagnostic imaging studies are unnecessary and have minimal clinical utility. Conclusion: Chronic post-traumatic headaches often occur, especially after minimally traumatic brain injury. The clinical picture is variable and may be similar to tension-type headaches and/or migraines.   Pendahuluan: Nyeri kepala dalam tujuh hari setelah cedera kepala atau setelah sadar kembali dari trauma kepala disebut nyeri kepala pasca-trauma (post-traumatic headache/PTHA); disebut sakit kepala pasca-trauma kronis atau kronis (CPTHA) jika berlangsung lebih dari tiga bulan setelah cedera. Kasus: Seorang laki-laki berusia 17 tahun dengan keluhan nyeri kepala sejak 3 bulan, 3 hari setelah kepala kiri terbentur karena jatuh dari kursi. Saat itu, pasien pingsan sekitar 15 menit, tidak ada keluhan setelah sadar. Nyeri dirasakan di sisi kiri kepala, berdenyut, intensitas ringan-sedang, terasa lebih berat jika ada suara keras atau cahaya terlalu terang. Diskusi: Nyeri kepala pasca-trauma didiagnosis secara klinis. Laboratorium dan studi pencitraan diagnostik rutin tidak diperlukan dan memiliki utilitas klinis minimal. Simpulan: Nyeri kepala pasca-trauma kronis sering terjadi, terutama setelah cedera otak traumatis minimal. Gambaran klinisnya bervariasi dan dapat mirip nyeri kepala tipe tegang dan/atau migrain  
HER2 positivity as a predictor of brain metastases in breast cancer: A systematic literature review Sanad, Sakinah Mar'ie; Adnyana, I Made Oka; Widyadharma, I Putu Eka
Malahayati International Journal of Nursing and Health Science Vol. 8 No. 8 (2025): Volume 8 Number 8
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/minh.v8i8.1159

Abstract

Background: Breast cancer remains one of the most prevalent and lethal malignancies among women globally, which leads to the critical importance of early detection and a more comprehensive approach to breast cancer management. Purpose: To investigate HER2 positivity as a predictor of brain metastases in breast cancer. Methods: A total of 23 peer-reviewed studies published between 2015 and 2025 were analyzed, including randomized trials, retrospective cohorts, prediction model studies, and registry-based evaluations. Eligibility was guided by the PICOTS framework, and databases searched included PubMed, Scopus, MDPI, Elsevier, SagePub, and BMC Cancer. Results: The review confirms that HER2 overexpression significantly correlates with earlier brain metastasis onset, increased incidence, and distinctive treatment response profiles. HER2 status also influences survival outcomes and benefits from targeted agents such as trastuzumab, tucatinib, and pyrotinib. HER2-low expression additionally showed intermediate risk profiles, while imaging and circulating tumor cell data added prognostic value. Conclusion: HER2 positivity is a robust, independent predictor of brain metastasis in breast cancer patients. Routine integration of HER2 profiling in CNS risk assessment models may improve early detection and therapeutic precision, ultimately enhancing clinical outcomes for high-risk populations.
Co-Authors Adriana Marsha Yolanda Agus Antara, Agus Anak Agung Ayu Putri Laksmidewi Anak Agung Ayu Suryapraba Anak Agung Bagus Ngurah Nuartha Anna Marita Gelgel Arimbawa, I Komang Ariswanda, I Gusti Agung Gede Artini, Ni Made Yuli Bhaskoro Adi Widie Nugroho, Bhaskoro Adi Widie Budiarsa, I Gusti Ngurah Ketut Desak Ketut Indrasari Utami Desak Made Widyanthari Devi, Gusti Ayu Putu Giti Livia Dewa Putu Gede Purwa Samatra Dewi, Ni Putu Mira Kardila Eric Hartono Tedyanto Haditya, Yogi Hakim, Lukman I Gusti Ngurah Ketut Budiarsa I Putu Eka Widyadharma Ida Ayu Made Vera Susiladewi Ida Ayu Sri Indrayani Ida Ayu Sri Wijayanti Ida Bagus Kusuma Putra IGN Budiarsa Indrayani, I.A. Sri Kesanda, I Made Phala Ketut Widyastuti Kumara Tini Laksmidwei, A A A Putri Lim, Demetria Jesica Lina Kamelia Mahadewi, Ni Putu Ayu Putri Ni Made Susilawathi Ni Made Yuli Artini Ni Putu Ayu Putri Mahadewi Ni Putu Witari Nyoman Angga Krishna Pramana P. Gde Daniswara Raditya Rahman Pranitha, Putu Diva Purwanto, Oky Dwi Putra, Ida Bagus Kusuma Putri Rossyana Dewi Putu Emilia Dewi Putu Gede Sudira Ramayanti, Ni Putu Nadia Richard Suherlim Risky Ilona Saputra Sanad, Sakinah Mar'ie Suryamulyawan, Kadek Adi Susilawathi, Ni Made Thomas Eko Purwata Tini, Kumara Tirtha, Putu Bagus Bramanthana Valentina Tjandra Dewi Widyastuti, Ketut