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All Journal Jurnal Veteriner Majalah Kedokteran Bandung Althea Medical Journal Jurnal Farmasi Klinik Indonesia Global Medical and Health Communication MNJ (Malang Neurology Journal) The Indonesian Biomedical Journal Universa Medicina Paediatrica Indonesiana Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Narra J Cermin Dunia Kedokteran Jurnal Neuroanestesi Indonesia Makara Journal of Health Research Cermin Dunia Kedokteran
Ramdan Panigoro
Biochemistry And Molecular Biology Division, Department Of Biomedical Sciences, Faculty Of Medicine, Universitas Padjadjaran, Bandung
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Journal : Paediatrica Indonesiana

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Nasopharyngeal bacterial carriage and antimicrobial resistance in underfive children with community acquired pneumonia Cissy B. Kartasasmita; Heda Melinda Duddy; Sunaryati Sudigdoadi; Dwi Agustian; Ina Setiowati; Tri Hanggono Ahmad; Ramdan Panigoro
Paediatrica Indonesiana Vol 41 No 11-12 (2001): November 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi41.6.2001.292-5

Abstract

Lung puncture is the best way to determine the etiology of pneumonia since it yields the highest rate of positive cultures. However, this procedure is difficult, especially for a study in the community. According to WHO, isolates to be tested for antimicrobial resistance in the community should be obtained from nasopharyngeal (NP) swabs. Previous studies support the use of NP isolates to determine antimicrobial resistance patterns of isolates from children with pneumonia. The aim of our study was to know the bacterial patterns of the nasopharynx in underfive children with community acquired pneumonia and their antimicrobial resistance. The study was carried out in 4 Primary Health Clinics in Majalaya sub-district, Bandung, Indonesia. All underfives with cough or difficult breathing and classified as having non-severe pneumonia (WHO guidelines), were included in the study. Nasopharyngeal swabs (CDC/WHO Manual) were obtained by the doctor, the swabs were placed in Amies transport medium and stored in a sterile jar before taken to the laboratory in the same day. All children were treated with co-trimoxazole. During the nine month study, 698 children with clinical signs of non-severe pneumonia were enrolled. About 25% of the nasopharyngeal specimens yielded bacterial isolates; the two most frequently found were S. pneumoniae and S. epidermidis. The antimicrobial resistance test to co-trimoxazole showed 48.2% S. pneumoniae strain had full resistance and 32.7% showed intermediate resistance to co-trimoxazole. This result is almost similar to other studies from Asian countries. It seems that H. influenzae is not a problem in the study area; however, further studies are needed.
Co-Authors Adi Imam Cahyadi Ahmad Rizal ahmad rizal Aih Cahyani Al Rasyid Alif Bagus Rakhimullah Alvinsyah Adhityo Pramono Anam Ong Anam Ong Anggraini Widjajakusuma Ani Melani Maskoen Asep Nugraha Hermawan Bashari, Muhammad H. Cissy B. Kartasasmita Cissy B. Kartasasmita Dewanto, Julius B Dewantoro, Julius Broto Diah Dhianawaty Dias Aryani Dwi Agustian Edhyana Sahiratmadja Edhyana Sahiratmadja Edhyana Sahiratmadja Elsa Pudji Setiawati Erick Khristian Fadhal M. Ahmad Fanny Adhy Putri Haryono Tansah, Haryono Heda M. Duddy Heda Melinda Duddy Helena Napitu, Helena Herman Susanto Ida Parwati Ina Setiowati Ina Setiowati Irianto, Gunawan Jeri Nobia Purnama Julius B Dewanto Julius Broto Dewanto, Julius Broto Kevin Dominique Tjandraprawira Khristian, Erick Lailiyya, Nushrotul Lelani Reniarti Lisda Amalia Lohghinee Khrisnan Lohghinee Khrisnan, Lohghinee Mas Rizky A.A Syamsunarno Mas Rizky A.A. Syamsunarno Masahiko Kurabayasi Mohammad Ghozali Mohammad Ghozali, Mohammad Mugia Bayu Rahardja Mugia Bayu Raharja Muhammad, Rifqi Y Neni Anggraeni Novi Vicahyani Utami Nur Atiik Nurul Setia Rahayu Nushrotul Lailiyya Pandji Irani Fianza Penggoam, Simeon Pramono, Alvinsyah Adhityo Pricilla Purushothman Purnama, Jeri N. Putri, Fanny Adhy Ratu Safitri Ratu Safitri Ratu Safitri Reni Ghrahani Rifqi Y Muhammad Rini Widyastuti Samsudin Surialaga Sari Puspa Dewi Shenny Dianathasari Santoso Simeon Penggoam Sunaryati Sudigdoadi Sunaryati Sudigdoadi Surbakti, Indra Murty Tatsuya Iso Tri H. Ahmad Tri Hanggono Achmad Tri Hanggono Ahmad Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani, Uni Wardoyo, Chandra Calista Wijaya, Michelle Angelica Yudi Mulyana Hidayat Yusuf Wibisono Yusuf Wibisono