Ramdan Panigoro
Biochemistry And Molecular Biology Division, Department Of Biomedical Sciences, Faculty Of Medicine, Universitas Padjadjaran, Bandung

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Journal : Althea Medical Journal

Factors Affecting Mortality in Adult Tetanus Patients Khrisnan, Lohghinee; Ong, Anam; Panigoro, Ramdan
Althea Medical Journal Vol 2, No 2 (2015)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (510.996 KB)

Abstract

Background: Tetanus is a devastating disease that is associated with high mortality. The aim of this study was to analyze the prognostic factors that were associated with high mortality in tetanus. Methods: This was an analytical study and the data was collected retrospectively from 1 January 2010–31October 2012 in the Department of Neurology, Dr. Hasan Sadikin General Hospital.Results: Out of hundred thirty two cases only 87 cases of tetanus patient have complete medical records. There were 54 male and 33 female. The age range was 35-49 years old. Mortality rate was high (32.18%). The most frequent wound site is extremities (85.07 %). The absence of post-injury tetanus vaccination was 75.86%, period of onset <48 hours was 67.82% and the use of mechanical ventilation and tracheostomy 36.07%. Mortality was significantly associated with an incubation period <7 days (p<0.05), presence of fever(p <0.05), co morbidity of autonomic storm (p<0.01), and the severity of the disease by grade 5 (p<0.05).Conclusions: Factors affecting the mortality in adult tetanus patients were significant for incubation period, fever, co morbidity and severity of the disease by grade. [AMJ.2015;2(1):157–61]
Factors Affecting Mortality in Adult Tetanus Patients Lohghinee Khrisnan; Anam Ong; Ramdan Panigoro
Althea Medical Journal Vol 2, No 2 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (510.996 KB)

Abstract

Background: Tetanus is a devastating disease that is associated with high mortality. The aim of this study was to analyze the prognostic factors that were associated with high mortality in tetanus. Methods: This was an analytical study and the data was collected retrospectively from 1 January 2010–31October 2012 in the Department of Neurology, Dr. Hasan Sadikin General Hospital.Results: Out of hundred thirty two cases only 87 cases of tetanus patient have complete medical records. There were 54 male and 33 female. The age range was 35-49 years old. Mortality rate was high (32.18%). The most frequent wound site is extremities (85.07 %). The absence of post-injury tetanus vaccination was 75.86%, period of onset <48 hours was 67.82% and the use of mechanical ventilation and tracheostomy 36.07%. Mortality was significantly associated with an incubation period <7 days (p<0.05), presence of fever(p <0.05), co morbidity of autonomic storm (p<0.01), and the severity of the disease by grade 5 (p<0.05).Conclusions: Factors affecting the mortality in adult tetanus patients were significant for incubation period, fever, co morbidity and severity of the disease by grade. [AMJ.2015;2(1):157–61]
Co-Authors Adi Imam Cahyadi Ahmad Rizal ahmad rizal Aih Cahyani Al Rasyid Alif Bagus Rakhimullah Alvinsyah Adhityo Pramono Anam Ong Anam Ong Anggraini Widjajakusuma Ani Melani Maskoen Asep Nugraha Hermawan Bashari, Muhammad H. Cissy B. Kartasasmita Cissy B. Kartasasmita Dewanto, Julius B Dewantoro, Julius Broto Diah Dhianawaty Dias Aryani Dwi Agustian Edhyana Sahiratmadja Edhyana Sahiratmadja Edhyana Sahiratmadja Elsa Pudji Setiawati Erick Khristian Fadhal M. Ahmad Fanny Adhy Putri Haryono Tansah, Haryono Heda M. Duddy Heda Melinda Duddy Helena Napitu, Helena Herman Susanto Ida Parwati Ina Setiowati Ina Setiowati Irianto, Gunawan Jeri Nobia Purnama Julius B Dewanto Julius Broto Dewanto, Julius Broto Kevin Dominique Tjandraprawira Khristian, Erick Lailiyya, Nushrotul Lelani Reniarti Lisda Amalia Lohghinee Khrisnan Lohghinee Khrisnan, Lohghinee Mas Rizky A.A Syamsunarno Mas Rizky A.A. Syamsunarno Masahiko Kurabayasi Mohammad Ghozali Mohammad Ghozali, Mohammad Mugia Bayu Rahardja Mugia Bayu Raharja Muhammad, Rifqi Y Neni Anggraeni Novi Vicahyani Utami Nur Atiik Nurul Setia Rahayu Nushrotul Lailiyya Pandji Irani Fianza Penggoam, Simeon Pramono, Alvinsyah Adhityo Pricilla Purushothman Purnama, Jeri N. Putri, Fanny Adhy Ratu Safitri Ratu Safitri Ratu Safitri Reni Ghrahani Rifqi Y Muhammad Rini Widyastuti Samsudin Surialaga Sari Puspa Dewi Shenny Dianathasari Santoso Simeon Penggoam Sunaryati Sudigdoadi Sunaryati Sudigdoadi Surbakti, Indra Murty Tatsuya Iso Tri H. Ahmad Tri Hanggono Achmad Tri Hanggono Ahmad Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani, Uni Wardoyo, Chandra Calista Wijaya, Michelle Angelica Yudi Mulyana Hidayat Yusuf Wibisono Yusuf Wibisono