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All Journal Sains Natural: Journal of Biology and Chemistry Jurnal Farmasi Indonesia JKPK (Jurnal Kimia dan Pendidikan Kimia) Jurnal Ners International Journal Of Science, Technology & Management (IJSTM) JUKESHUM: Jurnal Pengabdian Masyarakat International Archives of Medical Sciences and Public Health Jurnal Farmanesia Jurnal Pengabdian Masyarakat Tjut Nyak Dhien International Journal of Health, Engineering and Technology Journal of Pharmaceutical and Sciences. Jurnal Pengabdian Masyarakat Ilmu Kesehatan Media Penelitian dan Pengembangan Kesehatan Ulil Albab
Rida Evalina Tarigan
Institut Kesehatan Helvetia
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Uji efektivitas ekstrak etanol daun bayam hijau (Amaranthus hybridus L.) sebagai imunostimulan pada mencit putih jantan (Mus musculus) Tarigan, Rida Evalina; Sinaga, Arinda Agnes; Shufyani, Fahma
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.735

Abstract

The immune system plays a critical role in defending the body against pathogens, and enhancing its activity through immunostimulants is essential for improving health. This study aims to evaluate the immunostimulatory potential of ethanol extract from green amaranth leaves (Amaranthus hybridus L.) in male white mice (Mus musculus). The ethanol extract green amaranth leaves was prepared from dried green amaranth leaves and tested for its effect on phagocytic activity using the carbon clearance method. Phytochemical screening revealed the presence of flavonoids, saponins, tannins, and steroids. The animals were divided into five groups: negative control (0.5% Na CMC), positive control (Stimuno Forte®), and three experimental groups receiving varying doses of the ethanol extract (125 mg/kg, 250 mg/kg, and 500 mg/kg body weight). The results indicated that the ethanol extract significantly enhanced phagocytic activity, with the most optimal effect observed at 125 mg/kg body weight. The stimulation index increased with higher doses, demonstrating the dose-dependent immunostimulatory effect. The study concludes that the ethanol extract of green amaranth leaves can serve as an effective natural immunostimulant, with the 125 mg/kg body weight dose being the most effective in enhancing immune function in male white mice. These findings suggest the potential of green amaranth as a therapeutic agent for immune-related disorders.
Formulation Aroma Therapy Balm Preparations Combination Red Ginger Essential Oils (Zingiber officinale Roscoe) and Essential Oil Of Leaves Lemongrass (Cymbophogon nardus (L) Rendle) Sari, Melia; Chan, Adek; Faisal, Hendri; Tarigan, Rida Evalina; Nadeak, Eva Rosalina
International Journal of Health Engineering and Technology Vol. 2 No. 5 (2024): IJHET JANUARY 2024
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v2i5.170

Abstract

The essential oil combination of red ginger (Zingiber officinale Roscoe) and citronella leaves (Cymbophogon nardus (L.) Rendle) can be formulated as the most preferred balm and concentration preparation. Method type of experimental research. Experimental research is an experimental activity which aims to determine a symptom or influence that arises as a result of certain treatments. It was found in the organoleptic test that the preparation was in semi-solid form, dark yellow to pale yellow in color, with the aroma of mint and red ginger combined with citronella; the preparation is declared homogeneous; the pH of the aromatherapy balm with a combination of red ginger and citronella essential oils ranges from 5.23 – 5.63; the preparation does not cause irritation; and in the respondent's preference test, the F1 formula is more preferred. The essential oils of red ginger and citronella leaves with concentrations of 2.5%, 5%, 7.5% and 10% can be formulated into balm preparations. Test homogeneity and pH according to standars, there was no irritation in volunteers and the most popular balm preparation is formula F1 (containing 10% red ginger essential oil and leaves citronella concentration 2.5%).
Co-Authors Aqilah Sarah Nabila Chan, Adek Denny Satria Fahma Shufyani Faisal, Hendri Fitri , Khairani Friska Asnita Sari Simarmata Ginting, Evi Ekayanti Hendri Faisal Ismail Efendy Januariana, Neni Ekowati Julkardo Lase Khairani , Tetty Noverita Khairani, Cut Lilik Septiana Lutvia Lutvia Manaharawan Siregar, Syati Maria, Dulce Maryanti, Endang Masitah, Putri Mayang Sari MAYANG SARI Mayang Sari Melia Sari, Melia Mendrofa, Ester Lince Fiani Moraliza Lubis, Devi Muhammad Amin Nasution Muhammad Andry Nabila, Aqilah Sarah Nadeak, Eva Rosalina Natasya, Alfa Nurlita Putri, Nurlita Rina Monica Taruliana Sitorus Sajida, Nurul Shufyani, Fahma Siagian, Lenny Tiarmaida Sinaga, Arinda Agnes Siti Aisyah Surbakti, Chemayanti Tri Mayanti Vannissa Andriani Irawan Yustifin Sarumaha