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All Journal JURNAL GIZI INDONESIA Jurnal Kedokteran Diponegoro Jurnal Kesehatan Masyarakat Journal of Biomedicine and Translational Research Paediatrica Indonesiana Jurnal Medika Malahayati Medica Hospitalia PROFESI (Profesional Islam): Media Publikasi Penelitian Jurnal Akuntansi dan Keuangan Kontemporer (JAKK) IPTEK: Jurnal Hasil Pengabdian kepada Masyarakat Sanskara Pendidikan dan Pengajaran Jurnal Bisnis dan Manajemen West Science Prosiding Seminar Nasional dan Call For Paper Kebidanan Universitas Ngudi Waluyo Science Information System and Technology
Rina Pratiwi
Departments Of Pediatrics, Diponegoro University Medical School/Dr. Kariadi Hospital, Semarang, Central Java, Indonesia.
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Paediatrica Indonesiana

 1 
Prognostic factors for success in the Kangaroo Mother Care method for low birth weight babies Rina Pratiwi; Muhammad Sholeh Kosim; Noor Wijayahadi
Paediatrica Indonesiana Vol 55 No 3 (2015): May 2015
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (259.134 KB) | DOI: 10.14238/pi55.3.2015.142-6

Abstract

Background Low birth weight (LBW) is closely related to neonatal morbidity and mortality. Management of LBW infants in developing countries remains limited, due to the low availability of incubators. The Kangaroo Mother Care (KMC) method has been shown to be effective for newborns, especially LBW infants, in which skin-to-skin contact may be conducive for infants’ weight gain, thermoregulation, and heart rate stability.Objective To determine the prognostic factors for KMC success in LBW babies.Methods This cohort study included LBW infants at Dr. Kariadi General Government Hospital, Semarang, by a consecutive sampling method. Success of KMC was assessed by infant weight gain, as well as stabilization of temperature, heart rate, and respiration. Prognostic factors for KMC success that we assessed were birth weight, gestational age, KMC duration, age at KMC onset and maternal education level. Statistical analyses used were Chi-square and relative risk (RR) tests.Results Of 40 LBW infants, 24 were successful in KMC. Birth weight ≥ 1500 grams (RR 0.4; 95%CI 0.23 to 0.73; P=0.001)], gestational age ≥ 34 weeks (RR 0.94; 95%CI 0.46 to 1.89; P=1.00), KMC duration ≥ 65 minutes (RR 1.44; 95%CI 0.76 to 2.75; P= 0.215), high maternal education level (RR 1.25; 95%CI 0.76 to 2.04; P=0.408), and age at KMC onset >10 days (RR 2.69; 95%CI 1.14 to 6.32; P=0.003), were factors that related to the successful of KMC.Conclusion Age at KMC onset > 10 days was a prognostic factor for KMC success in low birth weight babies.
Vitamin D3 and seizure frequency in children with epilepsy using polypharmacy Aprilyani, Setya Puspa Dewi; Putranti, Alifiani Hikmah; Sareharto, Tun Paksi; Rahmadi, Farid Agung; Pratiwi, Rina
Paediatrica Indonesiana Vol. 65 No. 2 (2025): March 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.2.2025.122-8

Abstract

Background Children with epilepsy usually need vitamin D administration, primarily due to the effects of antiepileptic drugs (AEDs). The use of AEDs, particularly polypharmacy, can reduce serum 25(OH)D levels. Vitamin D improves the function of neurotransmitters furthermore boosting the seizure threshold. There has been relatively little study investigating the effects of vitamin D3 treatment on seizure frequency. Objective To compare seizure frequency before and after administering vitamin D3 to the children with epilepsy who used polypharmacy.  Methods Sixteen children with epilepsy and polypharmacy, aged 2-18 years, from the Pediatric Neurology Clinic, Dr. Kariadi Hospital, Semarang, were studied using a quasi-experimental approach with one group pretest-posttest. The vitamin D3 was given orally for two months with different dosages according to age andsubjects’ pretest serum 25(OH)D levels. Children with vitamin D insufficiency or deficiency were giventherapy dosage, and the normal vitamin D status were given supplementation dosage.Seizure frequency, serum 25(OH)D levels, and vitamin D status were assessed before and after treatment. Results Seizure frequency was significantly lower after vitamin D treatment for the entire group compared to pre- administration (P=0.019). For subjects with hypo-vitamin D levels pre-treatment, median seizure frequency was significantly decreased following normalization of vitamin D levels at one month (P=0.016) and two months (P=0.018) of vitamin D treatment. Using mean data, seizure frequency also significantly decreased at one month and at two months post-treatment. Conclusion Vitamin D3 administration is associated with an increase in serum 25(OH)D levels, as well as a decrease in seizure frequency. Vitamin D3 administration can significantly reduce seizure frequency in epilepsy patients undergoing polypharmacy who are vitamin D deficient.
Analysis of stool SCFA levels in weaning infants, the timing of weaning, and dietary intake Leliana, Vidya; Sareharto, Tun Paksi; Pratiwi, Rina
Paediatrica Indonesiana Vol. 65 No. 4 (2025): July 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.4.2025.279-85

Abstract

Background Short-chain fatty acids (SCFA) are metabolites of polysaccharides that cannot be digested by microbiota. Differences in SCFA profiles depend on infant diet and intestinal microbiota. The timing of weaning period from breast milk or formula to solid foods affects the transitional microbiome of the gut. Indonesian Pediatric Society recommend the weaning period at at 6 months old. Objective To analyze for differences in stool SCFA levels in weaning infants according to timing of weaning to introductory solid foods and dietary intake. Methods This cross-sectional study was conducted from February to August 2023 in Semarang Primary Health Care Unit. Subjects were infants aged 4-6 months, who underwent fecal SCFA laboratory analysis consisting of acetate, propionic, butyric, and valeric acids, and total SCFA levels, as well as carbohydrate, protein, lipid, and fiber intake assessment through a 3-day food recall processed with Nutrisurvey software of subjects who transitioned to solids before 6 months vs. at 6 months of age. We compared stool SCFA levels in the two groups using T-test analysis. Results Of 50 infants, 23 children (46%) started weaning from breast milk or formula to food at 6 months of age, and 27 children (54%) started weaning before 6 months of age. In this study, there were no significant differences in SCFA levels between those who started at 6 months and before 6 months (P>0.05). There was a weak positive correlation (r = +0.281) between protein intake and propionic acid level (P=0.0481) in all subjects. Conclusion There is no significant difference in SCFA level between starting the weaning period at 6 months and before. However, there is a positive correlation between protein intake and propionic acid, when the analysis was done on all subjects.
Co-Authors Adhie Nur Radityo Adhie Nur Radityo Adriyan Pramono Ahlun Ansar Ainil Mardiah Alifiani Hikmah Putranti Amallia Nugettsiana Setyawati Aprilyani, Setya Puspa Dewi Ari Andayani Arismunandar Arismunandar Darmiono, Darmiono Devia, Mutiara Diondra Eka Rizkiawan Dodik Pramono Ekowati, Liana Erna Mirani Farid Agung Rahmadi, Farid Agung Galuh Hardaningsih Galuh Hardaningsih, Galuh JC Susanto Judijanto, Loso Karsam Karsam Kusmiyati Tjahjono Maria Mexitalia Muhammad Sholeh Kosim Mulyadi Mulyadi Muslimin Muslimin Ningsih, Dewi Ayuh Nisrina Nur Haniyah Noor Wijayahadi Nyoman Suci Widyastiti Puspita Dewi, Wiwik Puspita Sari, Tria Rahmadiana, Rahmadiana Safrudin Safrudin Sari, Hastuti Indra Sari, Tri Elina Susilawati, Martvera Tun Paksi Sareharto Utami, Aras Vidya Leliana Wandawari, Andi Wardhani, Utari Christya Yulianti Wulandari