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All Journal Berkala Kedokteran Jurnal Penyakit Dalam Udayana ISM (Intisari Sains Medis) : Jurnal Kedokteran Neurologico Spinale Medico Chirurgico Jurnal Medika Hutama Jurnal Kesehatan Saintika Meditory Muhammadiyah Journal of Geriatric Cermin Dunia Kedokteran Jurnal Ilmu Kesehatan Indonesia (JIKSI) GANESHA MEDICINA MEDICINUS Jurnal Kedokteran Meditek Indonesian Journal of Endocrinology Metabolism and Diabetes (InaJEMD) Cermin Dunia Kedokteran Proceeding Mulawarman International Conference on Tropical Public Health
Ida Bagus Aditya Nugraha
Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran Universitas Udayana, RSUP Sanglah,Bali, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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The Comparison of X-ray Finding in Pulmonary Tuberculosis with and without Diabetes Mellitus Ida Bagus Aditya Nugraha; Wira Gotera; Made Nian Anggara
‎ InaJEMD - Indonesian Journal of Endocrinology Metabolic and Diabetes Vol. 1 No. 2 (2024): InaJEMD Vol. 1, No. 2
Publisher : PP PERKENI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66266/inajemd.v1i2.22

Abstract

Diabetes Mellitus patients are considered as a high-risk population for the development of Pulmonary Tuberculosis (PTB) by about three-fold. Diabetes Mellitus sufferers by glycated haemoglobin A1C (HbA1C) level. The relative risk (RR) of Tuberculosis (TB) was 3,1 (95% CI 1.6-5.9) for those with HbA1C ≥7%. There are several contradictory opinions regarding the radiological appearance of TBC sufferers with genuine effect of DM. Chest X-ray remains the primary investigation for the assessment of PTB. Pulmonary Tuberculosis is found predominantly in the lung apices. It is not clear whether DM can affect the presentation of TB. Thus, whether diabetic subjects present atypical radiological presentation of PTB is still controversial. There have been several studies with contradictory results regarding the differences in the radiological appearance of PTB patients with and without DM. Clinical studies have shown ambiguous results. Any other risk factors maybe associated with age, sex, smoking status, and nutrition status.
Karsinoma Endometrium pada Seorang Pasien dengan Diabetes Mellitus Tipe 2: Laporan Kasus: Laporan Kasus Teron, Thomas Aquinas Ehe; Nugraha, Ida Bagus Aditya; Gotera, Wira; Daniella, Dian; Riandika, Gede Vendi Cahyad
Cermin Dunia Kedokteran Vol 53 No 05 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i05.1007

Abstract

Introduction: Endometrial cancer is often associated with obesity, type 2 diabetes mellitus (T2DM), insulin resistance, and hyperinsulinemia. Case: A 71-year-old woman with a history of T2DM, hypertension, and obesity (body mass index/BMI 32.08 kg/m²) presented with intermittent abdominal pain and vaginal bleeding. She had undergone a curettage procedure two weeks earlier. Ultrasound examination revealed a hyperechoic mass in the uterine corpus, and histopathological examination following staging laparotomy confirmed type 2 endometrial carcinoma (high-grade serous carcinoma) with omental metastasis. The diagnosis was stage IVB endometrial carcinoma. During hospitalization, the patient received intravenous ceftriaxone, insulin glargine, and oral antihypertensive medications (ramipril and nifedipine). She was scheduled to receive systemic chemotherapy with carboplatin and paclitaxel, the standard regimen for advanced-stage, aggressive non-endometrioid endometrial cancer. Discussion: Diabetes mellitus, particularly when accompanied by chronic hyperglycemia, insulin resistance, and hyperinsulinemia, is associated with an increased risk of various cancers, including endometrial cancer, as well as a poorer prognosis. Factors such as obesity, age, estrogen exposure, and insulin therapy may exacerbate this risk, while biomarkers such as IGF-2 and IGFBP-3 have the potential to be used for early detection and risk assessment of endometrial cancer. Conclusion: This case highlights the strong link between T2DM, obesity, and aggressive endometrial cancer, emphasizing the importance of early detection and comprehensive management in patients with metabolic risk factors.
Co-Authors Adnyani, Ni Made Dwi Alvarocky, Rigky Anak Agung Gde Budhiarta Anak Agung Gde Budhiarta Anak Agung Gede Budhiarta Budhiarta, Anak Agung Gde Budiartha, Anak Agung Gede Daniella, Dian Dian Daniella Dwijo Anargha Sindhughosa Etick Pristyan Dewi FRANKY SIMARMATA Franky Simarmata Gede Kambayana Hendrajaya, Andre I Gusti Made Sumapta I Ketut Suastika I Made Pande Dwipayana I Made Siswadi Semadi I Made Siswadi Semadi I Made Siswadi Semadi I Putu Mahendra Adi Wardana I Wayan Wawan I Wayan Wita I. K. Suastika Ida ayu indira dwika Lestari Idris, Prizan Kenny Intizam, Marwa Humaira Ketut Suardamana Komang Agus Wira Nugraha Laksmi, Ida Ayu Sri Indra LP Dea Sasmita P Made Nian Anggara MADE RATNA SARASWATI . Marisye Christantia Ni Made Dwi Adnyani Ni Made Dwi Adnyani Novia, Juvita Pradiptha, I Putu Yupindra R. Prawira Bayu Putra Dewa Riandika, Gede Vendi Cahyad RIONALDO ANTHONIUS S., Hantono Saraswati, Putu Ayu Indah Semaradana, Wayan Giri Putra Sumapta, I Gusti Made Teron, Thomas Aquinas Ehe Wayan Evie Frida Yustin Wedari, Ni Nyoman Ira Santi Wijayanti, Ni Made Sri Winarka, Made Arie Dwi Wira Gotera