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All Journal JUKESHUM: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Tjut Nyak Dhien Jurnal Abdi Masyarakat Multidisiplin Journal of Pharmaceutical and Sciences.
Meutia Indriana
Fakultas Farmasi Dan Kesehatan Universitas Tjut Nyak Dhien, Medan, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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PENGGUNAAN EKSTRAK BIJI BUAH KESUMBA (Bixa orellana L.) SEBAGAI PEWARNA LIPSTIK Meutia Indriana; salman salman
Journal of Pharmaceutical and Sciences Vol 4 No 2 (2021): JPS Volume 4 Nomor 2 (2021)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v4i2.76

Abstract

Recently, there have been hundreds of lip color cosmetics on the market in various colors. However, not all lip colors are safe to use. Without realizing it, there are lip dyes that contain dyes that are dangerous and are prohibited because they can cause irritation to the skin and respiratory tract. Therefore, it is better to use natural dyes. One of the sources of natural dyes is the fruit of kesumba. Extracts from simplicia of kesumba seeds were made by percolation using 96% ethanol as a solvent. The lipstick formulation formula consists of Cera alba, vaseline alba, lanolin, carnauba wax, cetyl alcohol, oleum ricini, propylene glycol, titanium dioxide, butylhydroxytoluene, tween 80, rose oil (oleum rosae), and nipagin, as well as the addition of kesumba seed extract with concentrations of 15%, 17.5%, 20%, 22.5%, and 25%. Tests on the preparations made included examination of the melting point, homogeneity, lipstick strength, stability test against changes in shape, color, and odor during 30 days of storage at room temperature, smear test, and pH examination, and irritation test preference test (Hedonic test). The results of the research that the extract of the kesumba fruit seed can be formulated in lipstick preparations with a light yellow to dark maroon color. The formulation of the kesumba seed extract in the lipstick preparation shows that the preparation is relatively stable homogeneous, the melting point is 58°C, has a good lipstick strength, the pH ranges from 6.3 to 5.7 (according to the pH of the skin) easy to apply with an even color. , does not irritate, so it is safe to use; the pretty preferred preparations are preparations 2, 3, and 4, namely the formula with extracts of kesumba seeds with concentrations of 17.5%, 20%, and 22.5%.
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DARI BUNGA TUMBUHAN KECOMBRANG (Etlingera elatior Jack.) SECARA IN VITRO salman salman; Meutia Indriana
Journal of Pharmaceutical and Sciences Vol 4 No 2 (2021): JPS Volume 4 Nomor 2 (2021)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v4i2.75

Abstract

Traditionally, kecombrang flowers have been used to treat various diseases, including colds, earaches, blood purifiers, treat festering wounds and eliminate body odor. Various bacteria may cause ear diseases, purulent wounds, and body odor, so the kecombrang flower, which has been used traditionally to treat this disease, maybe due to its anti-bacterial activity against both Gram-positive and Gram-negative, so it is necessary to do research with the aim of ensuring the presence of anti-bacterial activity. This research includes collecting kecombrang flowers, plant identification, making Simplicia, phytochemicals, making kecombrang flower extracts by percolation with 96% ethanol extract. Testing anti-bacterial activity in vitro by diffusion method with punch holes on Mueller Hinton Agar medium, and used Ampicillin sulfate 20 g/ml as a control against Staphylococcus aureus, Streptococcus pneumonia, Escherichia coli, and Pseudomonas aeruginosa bacteria. Phytochemical screening showed the presence of the same group of compounds, namely alkaloids, flavonoids, steroids, glycosides, and essential oils. The results of the anti-bacterial activity test of the ethanol extract of the excellent kecombrang flower against Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, and less suitable for Pseudomonas aeruginosa.
PENGARUH PEMBERIAN TEH KOMBUCHA DAUN JATI BELANDA (Guazuma ulmifolia Lamk ) TERHADAP PENURUNANAN KADAR TRIGLISERIDA DARAH TIKUS PUTIH JANTAN (Rattus norvegicus) Salmah Handayani Lubis; Muharni Saputri; Nikmatul Hasanah; Meutia Indriana
Journal of Pharmaceutical and Sciences Vol 4 No 2 (2021): JPS Volume 4 Nomor 2 (2021)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v4i2.64

Abstract

Kombucha tea is high in antioxidants and can help reduce triglyceride levels by increasing the lipoprotein lipase enzyme activity to break down triglycerides. Previous studies have shown that giving Guazuna ulmifolia can reduce blood lipid levels because the content of tannins and mucilage can reduce fat absorption. This study aimed to determine the effect of giving kombucha tea leaves of Dutch teak to reduce blood triglyceride (TGD) levels of white male rats. This research method is experimental, including material collection, simplicia, phytochemical screening, kombucha fermentation of Dutch teak leaves, evaluating the quality of the preparation, testing triglyceride levels in rats with Electrode Based Biosensor technique. A total of 25 rats were divided into five groups; there is simvastatin its positive control (P1); negative control its blank (P2); the treatment group for teak kombucha tea leaves are 100 ml consecutively (P3); 150ml (P4); 200 ml (P5) induced using 80% egg yolk and 0.2% propiniltiourasil (PTU). This research method is experimental, including material collection, making simplicia, phytochemical screening, kombucha fermentation of Dutch teak leaves, evaluation of the quality of preparations, testing of triglyceride levels in rats with Electrode-Based Biosensor technique. This study was divided into 5 (five) groups, namely: P1; P2; P3, P4 and P5, administered orally to 25 rats that had been induced using 80% egg yolk and propinylthiouracil (PTU 0.2%). This study was divided into 5 groups, namely positive control simvastatin 0.025% given 1.44 ml (P1); negative control its (blank) was given as much as 3.6 ml (P2); Dutch teak leaf kombucha tea treatment group was given 100 ml/gBW in a row as much as 1.8 ml (P3); 150 ml/gBW was given as much as 2.7 ml (P4); 200 ml/gBW was given as much as 3.6 ml (P5).The results showed that in the 200 ml treatment group (P5) on day 7 to day 15, there was a decrease in TGD levels from 246.8 mg/dL to 93 ml/dL where this result was close to the positive control number (P1) of 238.6 mg/dL to 84 mg/dL. The results of the Kruskal-Wallis statistical test were p=0.98 (p>0.05), meaning that there was no significant difference between the test groups on the triglyceride levels obtained. The results showed that in the 200 ml treatment group (P5) on day 7 to day 15, there was a decrease in the TGD levels from 246.8 mg/dL to 93 ml/dL with the percentage reduction in triglycerides obtained by 37.68%, where these results close to the positive control number (P1) from 238.6 mg/dL to 84 mg/dL with the percentage reduction in triglycerides obtained by 35.20%. In testing triglyceride levels in the experimental group, different results were obtained in each experimental group The results of testing the triglyceride levels obtained, then carried out statistical tests in the form of non-parametric using the Khurskal Wallis method, from the test results obtained p = 0.098 (p = 0.05) which indicates that the data is normally distributed
EKSTRAK KULIT BUAH ANGGUR (Vitis vinifera L) SEBAGAI PEWARNA PADA FORMULASI LIPSTIK salman salman; Meutia Indriana
Journal of Pharmaceutical and Sciences Vol 5 No 1 (2022): JPS Volume 5 Nomor 1 (2022)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v5i1.90

Abstract

Grapes (Vitis vinifera L.) belong to the family Vitaceae. The color of the fruit varies. There are red, green and purple. The color of this wine contains anthocyanin dyes that can be used as natural dyes to replace synthetic dyes, the colors they contain are pretty intensive, so the researchers aimed to make lipstick formulations using natural dyes from grape skins. The lipstick formulation consisted of Cera alba, lanolin, vaseline alba, cetyl alcohol, oleum ricini, carnauba wax, propylene glycol, titanium dioxide, oleum rosae, butylhydroxytoluene, tween 80, and nipagin, as well as the addition of grape skin extract with a concentration of 15 %, 20%, 25%, 30%, and 35%. Tests on the preparations made include inspection of homogeneity, melting point, lipstick strength, stability test against changes in shape, color, and odor during 30 days of storage at room temperature, smear test, pH examination, and irritation test preference test (Hedonic test). From the research results, grape skin extract can be formulated into lipstick preparations with pink to dark red colors. Lipstick preparations with grape skin extract as a dye are pretty stable, homogeneous, melting point 59°C, have good lipstick strength, pH ranges from 3.7 to 3.9 (close to the pH of the lip skin) are easy to apply with an even color, and do not irritate. Irritation the preparation preferred by 30 panelists was preparation with a concentration of 25%.
Co-Authors Agustina Magdalena Aprilia Ulfa Ari Usman Bunga Rimtam Barus Dea Anggraini Desy Natalia Siahaan Erfan Wahyudi Ika Julianti Tambunan Jazilul Amira Kanne Dachi Kurniawan Sinaga Mariany Razali Muhammad Iskandar Muzakir Muzakir Muzakkir Muzakkir Nadhira, Ahmad Nikmatul Hasanah Nilsya Febrika Zebua, Nilsya Febrika Rahma Yulia Salmah Handayani Salmah Handayani Lubis Salman Salman Saputri, Muharni sari khalidya putri siti rahmi ningrum Sudewi Sudewi Sudewi Sudewi Sudewi Sudewi Sudewi Sudewi Sudewi Vivi Sofia Vriezka Mierza Windi Anggraini Yessi Febriani Yettrie Simarmata Zulfikar Zulfikar