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Stone recurrence among Indonesian kidney stone formers: a comprehensive analysis of genetic polymorphism, demographic, and clinical factors Atmoko, Widi; Savira, Missy; Fajriani, Rosalina; Wistara, Sevita Sathya; Asmarinah; Harahap, Alida Roswita; Witjaksono, Fiastuti; Werdhani, Retno Asti; Safriadi, Ferry; Hamid, Agus Rizal Ardy Hariandy; Birowo, Ponco; Rasyid, Nur; Taher, Akmal
Medical Journal of Indonesia Vol. 33 No. 3 (2024): September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.247596

Abstract

BACKGROUND The recurrence rate of kidney stone disease (KSD) can exceed 50% within 5 years. This study aimed to investigate factors associated with stone recurrence based on single nucleotide polymorphisms (SNPs) of the calcium-sensing receptor (CaSR) rs1801725 and rs1042636, demographic, and clinical profiles. METHODS We collected data on the demographic and clinical characteristics of 80 adult kidney stone formers from April 2021 to September 2022, including peripheral blood samples, morning and 24-hour urine, and 7-day water intake records. Real-time polymerase chain reaction was used to evaluate SNP. Comparisons were made between patients with recurrent and first-time stones. RESULTS 41% of 80 patients have experienced stone recurrence. Recurrent stone formers exhibited significantly higher 24-hour urine calcium excretion (p = 0.03) and lower serum calcium levels (p = 0.019) than first-time stone formers. Hypocitraturia (100%), low urine volume (78%), and hyperoxaluria (55%) were the main abnormalities of all patients. No significant differences were found in CaSR gene polymorphisms and other demographic, biochemical, or clinical parameters. CONCLUSIONS Recurrent stone formers had higher 24-hour urine calcium excretion and lower serum calcium levels. Other risk factors and CaSR polymorphisms may insignificantly affect KSD recurrence.
Comparing anastomosis techniques on ischemia time in multi-arterial kidney grafts: a systematic review and meta-analysis Hernawan Rahmat Muharia, Bayu; Situmorang, Gerhard Reinaldi; Rasyid, Nur; Rodjani, Arry; Birowo, Ponco
Medical Journal of Indonesia Vol. 34 No. 1 (2025): March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.257527

Abstract

BACKGROUND Kidney transplants with multiple renal arteries (MRAs) address donor shortages but carry higher vascular risks than single renal arteries. This study aimed to evaluate how different anastomosis techniques affect outcomes in kidney transplants with MRAs through meta-analysis and systematic review, concluding the continuous discussion about the best reconstructive strategy. METHODS A comprehensive search across 5 databases (PubMed, ScienceDirect, Cochrane Library, Web of Science, and the Cumulative Index to Nursing and Allied Health Literature) was conducted until December 17, 2024, to find studies comparing anastomoses technique in MRA grafts. Meta-analysis was performed using Review Manager software version 5.4, generating pooled effect estimates for mean difference (MD) and risk ratio (RR), two-sided p-values, and 95% confidence intervals (CIs). RESULTS Two retrospective cohort studies were included in the meta-analysis. There was no significant difference between end-to-side and side-to-side anastomosis in warm ischemia time (MD = 15.64, 95% CI: −6.82−38.10, p = 0.17) or cold ischemia time (MD = −16.74, 95% CI: −105.61−72.14, p = 0.71). The complication rate showed no significant variation between side-to-side and end-to-side anastomosis (RR = 2.38, 95% CI: 0.41−13.70, p = 0.33). Meta-analysis on graft function and rejection was impossible due to differences in measurements and the small number of studies. CONCLUSIONS Different anastomosis techniques for MRA grafts did not result in longer ischemia times or higher complication rates. Graft function and rejection rates were comparable between side-to-side and end-to-side anastomosis, suggesting both were equally feasible for renal transplants with MRAs. Further studies are required to verify these findings.
Reconstruction of Multiple Renal Arteries in Live Donor Kidney Transplantation: Moewardi Hospital Experience Muhammad Hilmy Labibi; Syaeful Agung Wibowo; Husein, Ali; Wibisono; Bimanggono Hernowo Murti; Suharto Wijanarko; Tusarawardaya , Setya Anton; Rodjani, Arry; Rasyid, Nur; Susanto , Agung; Putro , Prasetyo Sarwono
Plexus Medical Journal Vol. 4 No. 4 (2025): Agustus
Publisher : Fakultas Kedokteran, Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/plexus.v4i4.2292

Abstract

Background: Kidney transplant is the procedure for end stage renal disease (ESRD). This treatment has longer survival advantage than dialysis. Anatomical variations in the renal vasculature like multiple renal arteries, may increase surgical difficulties and influence postoperative outcomes. Case Presentation: We report a 46-year-old female living donor with two renal arteries on the left side of kidney. The recipient was her 25-year-old daughter with end stage renal disease due to systemic lupus erythematosus. A left open donor nephrectomy was completed without complications. The two renal graft arteries were side-to-side anastomosed each other, then an end-to-side anastomosis to the external iliac artery. The kidney achieved rapid reperfusion and returned to function immediately. Doppler ultrasound examination showed the normal perfusion. The creatinine level was 1.2 mg/dL on second day postoperative and stable at 0.8 mg/dL during a three-month follow-up. Conclusion: This case highlights the feasibility of transplanting a kidney from a donor with multiple renal arteries, emphasizing the critical role of comprehensive preoperative evaluation and meticulous surgical planning in achieving optimal outcomes.
Metode Anestesi Terkini untuk Vasektomi Tanpa Pisau Bedah: Sebuah Tinjauan Sistematik Rahman, Fakhri; Birowo, Ponco; Rasyid, Nur
Majalah Kedokteran Indonesia Vol 69 No 4 (2019): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.69.4-2019-67

Abstract

Introduction: This study was aimed to described current anesthesia methods to facilitate no-scalpel vasectomy procedure. Methods: A systematic review based on PRISMA guideline was conducted which included all the studies discussing no-scalpel vasectomy and focusing on its anesthesia method. Outcomes searched were pain during anesthesia and procedure. Literature search was done through search engines (PubMed, EBSCO Host and Cochrane library) using (“no-scalpel vasectomy” OR “scalpel-free vasectomy” OR “vasectomy”) AND (“anesthesia”) as keywords and through manual search. Literature selection process was done by two reviewer and qualified studies were subjected to quality assessment. Results: A total of 446 literatures were found and five studies satisfying the eligibility criteria and discussed following anesthesia methods: local infiltration anesthesia (LIA), spinal cord block (SCB), no-needle anesthesia (NNA), mini-needle anesthesia (MNA) and eutectic mixture of local anesthetic (EMLA). This study showed that the average score of pain (VAS 1-10) during no-scalpel vasectomy procedure for LIA, combination of LIA and SCB, NNA, MNA and combination of LIA and EMLA were 1.86 – 2.7, 0.64, 0.66 – 2.13, 0.66 and 2.15, respectively. Conclusion: Combination of LIA and SCB, NNA and MNA showed promising results as anesthesia methods. However, these promising results should be further proven by more studies.
Association between material and design used in a ureteral stent with complication in ureteral catheterisation: A systematic review Pakpahan, Karimul Abdi; Birowo, Ponco; Rasyid, Nur; Atmoko, Widi
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 15, No 1, (2024)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol15.Iss1.art13

Abstract

The double-J stent is one of the ureteral catheters with curved ends for fixation. Since its introduction in 1978, catheterisation using a double-J stent has become one of the most frequently performed procedures in urology. However, double-J stents may lead to various complications, causing patient discomfort, pain, and bladder symptoms. Technological advancements in stent design aim to minimise these complications and enhance comfort. This review aimed to determine the association between the material and design used in ureteral stents and complications in ureteral catheterisation. We conducted a systematic review following the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) checklist. Screening based on specific inclusion criteria was employed to select potential studies. A database search yielded a total of 124 studies. Nine full texts were evaluated for eligibility, resulting in the exclusion of one paper. Our findings indicate that ureteral stent insertion significantly increases the frequency of pain and urinary symptoms while decreasing overall health. The choice of materials and design plays a crucial role in minimising pain and improving the quality of life for patients. Physical properties such as firmness and tensile strength also affect the quality of life, with higher firmness and tensile strength causing lower quality of life. Stent material and design choice were context-dependent. Using soft stents and specialised soft distal pigtails has been shown to reduce patient stent-related symptoms. Silicone stents showed the least bladder symptoms than polymeric stents. Polymeric stents also showed no difference in utility from metallic stents for long-term usage.
Clinical risk factors of recurrent kidney stone disease: a cohort retrospective study in a tertiary referral hospital Atmoko, Widi; Febriyani; Savitri, Ary Indriana; Uiterwaal, Cuno; Setiati, Siti; Hamid, Agus Rizal Ardy Hariandy; Birowo, Ponco; Rasyid, Nur
Medical Journal of Indonesia Vol. 32 No. 4 (2023): December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.247166

Abstract

BACKGROUND Nephrolithiasis or kidney stone disease (KSD) is common worldwide. Despite various effective treatment strategies, KSD recurrence remains a problem. This study aimed to investigate the risk factors of KSD recurrence. METHODS This retrospective cohort study used medical records of all patients who came to the Department of Urology, Cipto Mangunkusumo Hospital, Jakarta, from January 2014 to December 2019, with asymptomatic and symptomatic KSD. Demographic information, clinical data, exposure to risk factors, and recurrent KSD diagnosis were collected. Univariate and multivariate analyses using logistic regression were performed to determine the significant risk factors. RESULTS We reported 325 patients with a median age of 52 years. More than half of the patients were males and from Java. Staghorn stone dominated the KSD types found in 181 patients (55.7%). After undergoing percutaneous nephrolithotomy, 214 patients (65.8%) became stone-free. However, about 40.6% of them later developed recurrent KSD. The adjusted odds ratio in recurrent KSD were 1.46 (95% confidence interval [CI] 1.33–1.59) for younger age, 1.86 (95% CI 1.61–2.07) for overweight–obese, 2.13 (95% CI 1.89–2.31) for less fluid intake, 1.81 (95% CI 0.97–2.12) for routine tea consumption, 1.24 (95% CI 1.06–1.84) for routine vegetables consumption, 2.27 (95% CI 1.83–2.84) for a family history of KSD, and 2.08 (95% CI 1.77–2.39) for diabetes mellitus (DM). CONCLUSIONS Most patients with recurrent KSD were younger, overweight/obese, had less fluid intake, a family history of KSD, and DM. Modifying a healthy lifestyle and a balanced diet is important to prevent KSD recurrence.
Development of kidney transplantation as a healthcare development model to achieve Indonesia Emas 2045 Rasyid, Nur; Susalit, Endang; Rodjani, Arry
Medical Journal of Indonesia Vol. 32 No. 3 (2023): September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.com.237171

Abstract

PENGARUH TINGKAT KUNJUNGAN WISATAWAN TERHADAP PENDAPATAN MASYARAKAT DI KAWASAN WISATA TANJUNG BAYANG MAKASSAR MAKASSAR nuhung, mahmud; Nuryana, Ina; Rasyid, Nur
Jurnal Ekonomi Balance Vol. 10 No. 1 (2014): (June 2014)
Publisher : Perpustakaan dan Penerbitan Unismuh Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26618/jeb.v9i1.1863

Abstract

Penelitian ini bertujuan untuk mengetahui seberapa besar tingkat kunjungan wisatawan terhadap tingkat pendapatan masyarakat, jenis data yang digunakan adalah data kualitatif dan kuantitatif serta analisis deskriptif. Jenis dan sumber data yang digunakan adalah 30 responden kuesioner kepada pedagang dan wawancara. Metode yang digunakan dalam penelitian ini adalah analisis regresi linier sederhana. Hasil perhitungan Uji t menunjukkan bahwa t hitung = 9,901, pada α 5% diperoleh ttabel = 1,625 karena t hitung, > ttabel, maka dapat disimpulkan bahwa variabel bebas dalam penelitian ini dapat menerangkan variabel independen memiliki pengaruh yang signifikan 0,000 lebih kecil dari 0,05 terhadap variabel dependen yaitu 0,003,Hasil perhitungan Uji F adalah F hitung > dari F tabel (4,495 >1,542) yang artinya Tingkat kunjungan berpengaruh signifikan tehadap tingkat pendapatan. hasil perhitungan koefisien determinasi (R2) adalah 0, 647a, Artinya adalah pendapatan sebesar 42 % dipengaruhi oleh tingkat kunjungan, dan sisanya sebesar 58% dipengaruhi oleh faktor lain yang tidak diteliti atau diluar model penelitian 
PENGARUH SISTEM PEMBERIAN HONOR TERHADAP PENINGKATAN KINERJA PENGURUS PROGRAM NASIONAL PEMBERDAYAAN MASYARAKAT MANDIRI PERDESAAN KABUPATEN TAKALAR nuhung, mahmud; Nuryana, Ina; Rasyid, Nur
Jurnal Ekonomi Balance Vol. 9 No. 2 (2013): (December 2013)
Publisher : Perpustakaan dan Penerbitan Unismuh Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26618/jeb.v8i2.1865

Abstract

Permasalahan penelitian ini yaitu apakah sistem pemberian honor dapat berpengaruh terhadap peningkatan kinerja pengurus Program Nasional Pemberdayaan Masyarakat Mandiri Perdesaan Kabupaten Takalar. Metode analisis yang digunakan dalam penelitian ini adalah metode Analisis regresi linear sederhana. Metode pengumpulan data yang digunakan adalah Penelitian Pustaka (Library Research) dan Penelitian Lapang (Field research) untuk memperoleh data kualitatif dan data kuantitatif dimana penelitian yang menghasilkan dokumen-dokumen dan keterangan-keterangan dalam bentuk angka-angka serta data lainnya melalui pengamatan dan kuesioner. Tujuan dari penelitian ini adalah untuk membuktikan pengaruh sistem pemberian honor terhadap peningkatan kinerja pengurus Program Nasional Pemberdayaan Masyarakat Mandiri Perdesaan Kabupaten Takalar. Pengujian hipotesis dalam penelitian ini adalah menggunakan uji F dan uji t. Dari hasil uji t untuk variabel X (sistem pemberian honor) diketahui bahwa nilai thitung (2,854) > nilai ttabel (2,681) maka Ho dapat di tolak. Ini berarti bahwa sistem pemberian honor signifikan berpengaruh terhadap peningkatan kinerja pengurus Program Nasional Pemberdayaan Masyarakat Mandiri Perdesaan Kecamatan Mangarabombang Kabupaten Takalar.
PENGARUH SISTEM PEMBERIAN HONOR TERHADAP PENINGKATAN KINERJA PENGURUS PROGRAM NASIONAL PEMBERDAYAAN MASYARAKAT MANDIRI PERDESAAN KABUPATEN TAKALAR nuhung, mahmud; Nuryana, Ina; Rasyid, Nur
Jurnal Ekonomi Balance Vol. 10 No. 2 (2014): (December 2014)
Publisher : Perpustakaan dan Penerbitan Unismuh Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26618/jeb.v12i1.1869

Abstract

Permasalahan penelitian ini yaitu apakah sistem pemberian honor dapat berpengaruh terhadap peningkatan kinerja pengurus Program Nasional Pemberdayaan Masyarakat Mandiri Perdesaan Kabupaten Takalar. Metode analisis yang digunakan dalam penelitian ini adalah metode Analisis regresi linear sederhana. Metode pengumpulan data yang digunakan adalah Penelitian Pustaka (Library Research) dan Penelitian Lapang (Field research) untuk memperoleh data kualitatif dan data kuantitatif dimana penelitian yang menghasilkan dokumen-dokumen dan keterangan-keterangan dalam bentuk angka-angka serta data lainnya melalui pengamatan dan kuesioner. Tujuan dari penelitian ini adalah untuk membuktikan pengaruh sistem pemberian honor terhadap peningkatan kinerja pengurus Program Nasional Pemberdayaan Masyarakat Mandiri Perdesaan Kabupaten Takalar. Pengujian hipotesis dalam penelitian ini adalah menggunakan uji F dan uji t. Dari hasil uji t untuk variabel X (sistem pemberian honor) diketahui bahwa nilai thitung (2,854) > nilai ttabel (2,681) maka Ho dapat di tolak. Ini berarti bahwa sistem pemberian honor signifikan berpengaruh terhadap peningkatan kinerja pengurus Program Nasional Pemberdayaan Masyarakat Mandiri Perdesaan Kecamatan Mangarabombang Kabupaten Takalar.
Co-Authors Abdul Aziz Rani Achmad Fauzi Adianti Khadijah, Adianti Agi Satria Putranto Agus Rizal Ardy Hariandy Hamid, Agus Rizal Ardy Hariandy Akmal Taher Albertus Marcelino Alfarissi, Fekhaza Ari Astram, Ari Ari Basukarno, Ari Ari Fahrial Syam Arief Hakiki Arry Rodjani Asmarinah Bagus Baskoro Bimanggono Hernowo Murti Bimanggono Hernowo Murti, Bimanggono Hernowo Brodjonegoro, Sakti R Budi Wiweko C Susilo, C Chaidir A. Mochtar Chaidir Arif Mochtar CHAIDIR MOCHTAR, CHAIDIR charles johanes, charles Chudahman Manan Dadang Makmun Daldiyono Daldiyono Danarto, Raden Devintha Tiza Ariani donny eka putra, donny eka Dyandra Parikesit, Dyandra Endang Susalit Endrika Noviandrini, Endrika Fajriani, Rosalina Fakhri Rahman, Fakhri Febriyani Ferry Safriadi Fiastuti Witjaksono Gerhard Reinaldi Situmorang, Gerhard Reinaldi Harahap, Alida Roswita Hariwibowo, Rinto Harrina Erlianti Rahardjo, Harrina Erlianti Hendri, Ahmad Z Hernawan Rahmat Muharia, Bayu Hery Tiera Husein, Ali I Putu Gde Sanjaya, I Putu Ikhlas A. Bramono, Ikhlas A. Ina Nuryana, Ina Indah S. Widyahening Indrawarman Soeroharjo Irfan Wahyudi Isaac A. Deswanto, Isaac A. Islianti, Putri Iradita Ivan Rizal Sini, Ivan Rizal Marcellus Simadibrata Maruhum B.H. Marbun Mewahyu Dewi, Mewahyu Michelle Eva Muhammad Hilmy Labibi Murdani Abdullah Namira Kesuma Jelita Nuhung, Mahmud P Pryambodho, P Pakpahan, Karimul Abdi Pande Made Wisnu Tirtayasa Ponco Birowo Prahara Yuri Prasetyo, Dimas Tri Pudji Sari Puji Sari Putra, Donny E. Putro , Prasetyo Sarwono Rainy Umbas Rama Firmanto, Rama Retno Asti Werdhani Savira, Missy Savitri, Ary Indriana Siti Setiati Soeroto, Adhitama A. Suharto Wijanarko Susanto , Agung Syaeful Agung Wibowo Tommie Prasetyo, Tommie Tri Endah Suprabawati Tri Prasetyo, Dimas Tusarawardaya , Setya Anton Uiterwaal, Cuno Vinny Verdini Wibisono Widi Atmoko Widyasmara, Her Bayu Wistara, Sevita Sathya Yopie Tjandradiguna Satyawan Zulfikar Ali, Zulfikar