Kaka Renaldi
Division Of Gastroenterology, Pancreatobiliary, And Digestive Endoscopy Department Of Internal Medicine, Faculty Of Medicine, Universitas Indonesia/ Dr. Cipto Mangunkusumo National General Hospital, Jakarta

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The Role of GERD Questionnaire (GERD-Q) for Reflux Esophagitis Kaka Renaldi
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 21, No 3 (2020): VOLUME 21, NUMBER 3, December 2020
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (286.18 KB) | DOI: 10.24871/2132020169-170

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Gastrointestinal Endoscopy in the Time of Covid-19 Pandemic: Current Guidelines and Experience From Indonesian Tertiary Endoscopy Centre Hasan Maulahela; Jaffray DP Rambak; Hilda Nurmalihah; Kaka Renaldi; Achmad Fauzi; Murdani Abdullah; Marcellus Simadibrata; Ari F Syam; Roy Soetikno; Dadang Makmun
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 21, No 1 (2020): VOLUME 21, NUMBER 1, April 2020
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (290.242 KB) | DOI: 10.24871/211202045-52

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Coronavirus disease-19 (COVID-19) is a respiratory disease caused by novel SARS-CoV-2. The disease has become a global pandemic since March 2020. Transmission of the disease is rapid and contagious through droplets and contaminated environments. Meanwhile, gastrointestinal endoscopy is a procedure that has a high risk of transmitting COVID-19. Proper strategies are needed to prevent transmission of the virus in the endoscopic unit. Some literature has published the guidelines for prevent COVID-19 in endoscopic units such as guidelines by AGA, APSDE, ESGE and ESGENA. These guidelines state that strategies for prevent the COVID-19 transmission in endoscopy unit must be done from before the procedure, during the procedure until after the procedure. These strategies must be followed by all patients and health care providers who working in endoscopy units.
Endoscopic Ultrasonography (EUS) Compared with Magnetic Resonance Cholangiopancreatography (MRCP) in Diagnosing Patients with Malignancy Causing Obstructive Jaundice Kaka Renaldi; Rudy Kurniawan; Dadang Makmun
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 22, No 1 (2021): VOLUME 22, NUMBER 1, April 2021
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (574.731 KB) | DOI: 10.24871/221202129-36

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Background: The common etiologies of obstructive jaundice were biliary stone and biliary neoplasms. The gold standard to diagnose malignancy causing obstructive jaundice is endoscopic retrograde cholangiopancreatography (ERCP) with sensitivity and specificity of 95% and 100%. However, ERCP is an invasive procedure associated with several complications such as bleeding, pancreatitis, and perforation. Other modalities include endoscopic ultrasonography (EUS) and magnetic resonance cholangiopancreatography (MRCP). Thus, we aim to evaluate the sensitivity and specificity of EUS with MRCP in patients with malignancy causing obstructive jaundice.Method: This was a cross-sectional study that calculates the sensitivity and specificity of EUS and MRCP in diagnosing malignancy causing obstructive jaundice compared with the gold standard, histopathology examination from ERCP. The study was conducted in the Medical Record Unit, Gastroenterology Division, Dr. Cipto Mangunkusumo National General Hospital, on January – March 2019 by using a consecutive sampling method. The date of diagnosis was collected from the medical record within five years. Subjects were selected based on inclusion criteria which include patients aged ≥ 18 years old who were diagnosed with malignancy causing obstructive jaundice by ERCP, and had underwent EUS or MCRP with a maximum interval of 3 months to ERCP. The exclusion criteria include patients with previous evidence of biliary tract malignancy or concurrent parenchymal jaundice. Statistical analysis was performed using IBM SPSS Statistics 20.Results: There were 54 subjects with a mean age of 56.48 ± 11.37 years. Subjects consisted of 29 (53.7%) males and 25 (46.3%) females. The median period between EUS to ERCP was 0-33 days, while MRCP to ERCP was 1-53 days. The sensitivity, specificity, positive predictive value, and negative predictive value to diagnose obstructive jaundice due to malignancy were 96%, 60%, 96%, 60% in EUS, and 90%, 40%, 94%, 29% in MRCP, respectively.Conclusion: EUS was more superior to MRCP in the diagnosis of  malignancy causing obstructive jaundice.
Diagnostic Approach and Treatment of Dieulafoy's lesion Saifuddin, Anshari; Renaldi, Kaka; Situmorang, Indah
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 2
Publisher : UI Scholars Hub

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Dieulafoy’s lesion is a rare cause of upper gastrointestinal bleeding but become an important etiology. Pathogenesis of the disease evolved from earlier of its invention till now. It has been stated in recent study that the etiology of this disease is vary, from age to genetic. Size and arteriol configuration abnormality has been known as the main pathogenesis of the disease. Endoscopic procedure become the primary diagnostic tool, which effectiveness reached more than 90%. However, in some situation, it’s difficult to find the abnormality by endoscopic procedure. Hemostatic procedure via endoscopy is the main therapy of Dieulafoy’s lesion, which has been progressed from thermal coagulation, mechanical procedure, and epinephrine injection. The development of medical technology has made the better prognosis of the disease.
Diagnosis and Treatment of Celiac Disease Oktadiana, Harini; Abdullah, Murdani; Renaldi, Kaka
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 3
Publisher : UI Scholars Hub

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Celiac disease is a reversible, proximal immune enteropathy resulting from the interaction of dietary gluten with the intestinal immune system. Celiac disease can produce varied manifestations and may develop at any age. New cases have increased substantially, due to increase awareness and better diagnostic tools. Standard diagnosis of celiac disease is based on positive serologic tests and histopathologic examination of duodenal biopsies. Treatment of celiac disease with free gluten diet will improve symptoms, quality of life, reduce risk of malignancy and complication. Nowadays, treatment strategy of celiac disease with non-dietary therapies is still underdevelopment.
Gastrointestinal Bleeding as a Manifestation of IntestinalTuberculosis in Leprosy Patients with Reversal Reaction andHistory of Long-Term Steroid Therapy Gebrina, Meutia; Nursyirwan, Saskia Aziza; Soewondo, Pradana; Fauzi, Achmad; Renaldi, Kaka
Jurnal Penyakit Dalam Indonesia Vol. 3, No. 1
Publisher : UI Scholars Hub

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Intestinal tuberculosis is difficult to be diagnosed. Signs and symptoms usually are not specific, and the results of diagnostic tools are frequently negative. One of the unusual symptoms of intestinal tuberculosis is gastrointestinal bleeding, which should increase the awareness of clinical practitioners.
Drug-induced Myelotoxicity in Patients with Crohn’s Disease Renaldi, Kaka; Hosea, Fransiscus Nikodemus
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 25, No 2 (2024): VOLUME 25, NUMBER 2, August, 2024
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2522024%p

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As a chronic granulomatous disease, Crohn’s disease (CD) poses a significant insinuation on morbidity and low quality of life. Long-term treatment is needed to control the disease activity. Observation and evaluation of disease activity are principal practices in treating CD, and sometimes clinicians tend to overlook the adverse effects of therapy that may occur and resemble disease progression.Hereby, we presented a 76-year-old female with a 10-year history of Crohn’s disease who came to our emergency room with general weakness one week before admission. She complained of hematochezia and abdominal pain in the last month. She had been taking mesalazine 2x500 mg PO and azathioprine 2x50 mg PO in the previous three years. She was diagnosed with lung cancer six months before admission and had been prescribed erlotinib 1x150 mg PO in the last six weeks. Upon admission, pancytopenia was found in the blood study. Hematochezia, along with anemia and abdominal pain, might occur due to either disease activity or the adverse effects of the medication.Thorough observation and clinical evaluation regarding disease activity and side effects are required to manage Crohn’s disease comprehensively. 
Current Diagnosis and Treatment of Choledocholithiasis Renaldi, Kaka; Firman, Fauzan Hertrisno
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 24, No 3 (2023): VOLUME 24, NUMBER 3, December, 2023
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2432023256

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The presence of gallstones in the common biliary duct is known as choledocholithiasis. Obstructive jaundice is the main clinical manifestation, which can cause acute cholangitis characterized by fever, jaundice, and right upper quadrant abdominal pain. The best diagnostic modality for choledocholithiasis is magnetic resonance cholangiopancreatography (MRCP). The treatment of choledocholithiasis involves extraction of gallstones using endoscopic retrograde cholangiopancreatography (ERCP), followed by stenting, and then cholecystectomy.
Peutz-Jeghers Syndrome: A Case Report and Literature Review in Indonesia Renaldi, Kaka; Friatna, Yudha
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 25, No 3 (2024): VOLUME 25, NUMBER 3, December, 2024
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/253202470-74

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Background: Peutz-Jeghers Syndrome (PJS) is a rare hereditary polyposis syndrome that is autosomal dominant and has the main characteristics of hamartoma polyps, mucocutaneous pigmentation, and increased susceptibility to malignancy. Case: This case report presented a 19-year-old man referred from a secondary hospital with complaints of diarrhea for one month before hospital administration. The symptoms happened five times a day with residue in the stool. Mucus or bleeding was not found. Around ten days prior, the polyp came out from the anus, but the patient could pull it back by himself. Diarrhea had been recurring since 2014. The patient then underwent polypectomy (while still children) and until now has undergone polypectomy 11 times. Abdominal CT scan showed multiple polyps with varying morphology in the luminal mucosa of the duodenum, jejunum, ileum, descending colon, sigmoid colon, and rectum, in accordance with the presentation of Peutz-Jeghers syndrome. The colonoscopy examination found a Peutz-Jeghers appearance after a polypectomy with a hemoclip installed. The patient was diagnosed with Peutz-Jeghers Syndrome post polypectomy. The patient received a plan for post-operative complete blood count examinations and periodic colonoscopies. Conclusion: PJS is an important diagnosis to consider in young patient with polyposis, even without mucocutaneous pigmentation. 
Nizatidine and Acotiamide: New Treatment Combination for Functional Dyspepsia? Renaldi, Kaka
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 26, No 1 (2025): VOLUME 26, NUMBER 1, April, 2025
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/26120251-3

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Co-Authors -, Resultanti Abdul Aziz Rani Abdul Aziz Rani Achmad Fauzi Achmad Fauzi Achmad Fauzi ACHMAD FAUZI Aditya Rachman Aditya Rachman Aditya Rachman, Aditya Adityo Susilo, Adityo Aisyah - Amanda P Utari, Amanda P Amanda Pitarini Utari Andika Indrarespati Anshari Saifuddin Anshari Saifuddin, Anshari Anthony Eka Wijaya Anthony Eka Wijaya Ari F Syam Ari F Syam Ari Fahrial Syam Ari Wijayanti Atikah Isna Fatya Batara Bisuk Chudahman Manan Chudahman Manan Dadang Makmun Daldiyono Daldiyono Daldiyono Daldiyono Daniel Martin Simadibrata Daniel Martin Simadibrata E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Edy Rizal Wahyudi Elli Arsita Elli Arsita Ening Krisnuhoni Fatya, Atikah Isna Fiastuti Witjaksono Firman, Fauzan Hertrisno Friatna, Yudha Haloho, Raja Mangatur Harini Oktadiana Harini Oktadiana, Harini Hasan Maulahela Hasan Maulahela Hasan Maulahela, Hasan Hidayat, Leonardus Wibowo Hilda Nurmalihah Hosea, Fransiscus Nikodemus Ika Prasetya Wijaya Ikhwan Rinaldi Indah Situmorang Indra Marki Indra Marki Indrarespati, Andika Jaffray DP Rambak Jeffri Gunawan Kusumaningrum, Profitasari Marcellus Simadibrata Marcellus Simadibrata Marcellus Simadibrata Marcellus Simadibrata Marcellus Simadibrata Meutia Gebrina Meutia Gebrina, Meutia Murdani Abdullah Murdani Abdullah Murdani Abdullah Murdani Abdullah Murdani Abdullah Mustika Dian Permana Mustikarani, Dewi Mutiara, Rizka Muzellina, Virly Nanda Nury Dyah Nury Dyah, Nury Permana, Mustika Dian Prabowo, Muhamad Reza Pradana Soewondo Pradana Soewondo Pratiwi, Amalia Nur Rabbinu Rangga Pribadi Rabbinu Rangga Pribadi Raja Mangatur Haloho Raja Mangatur Haloho Raymond R. Tjandrawinata Rezky Aulia Nurleili, Rezky Aulia Rino Alvani Gani Rizka Mutiara Roy Soetikno Rudy Kurniawan Rumagesan, Djahalia Saskia Aziza Nursyirwan Saskia Aziza Nursyirwan Saskia Aziza Nursyirwan, Saskia Aziza Shakinah, Sharifah Sharifah Sakinah Simadibrata, Daniel Martin Susanto, Liana W Tandan, Manu Teddy Septianto Wulandari, Yohannessa Yohannessa Wulandari