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All Journal IAES International Journal of Artificial Intelligence (IJ-AI) SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN snimed INDONESIAN JOURNAL OF LEGAL AND FORENSIC SCIENCES Jurnal Pendidikan dan Pembelajaran Kimia (JPPK) Mutiara Medika: Jurnal Kedokteran dan Kesehatan Berkala Kedokteran JURNAL TEKNIK INFORMATIKA DAN SISTEM INFORMASI ComTech: Computer, Mathematics and Engineering Applications YARSI Medical Journal Jurnal Informatika dan Rekayasa Elektronik Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Jurnal Sains, Nalar, dan Aplikasi Teknologi Informasi Biomedika Berkala Ilmiah Kedokteran dan Kesehatan Masyarakat
Linda Rosita
Departemen Patologi Klinik, Fakultas Kedokteran, Universitas Islam Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Public Health

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Correlation between Hemoglobin Reticulocytes and Ferritin in Chronic Kidney Disease Patients Undergoing Hemodialysis at PKU Bantul Muhammad Salman Shalahuddin; Linda Rosita
Berkala Kedokteran Vol 17, No 2 (2021)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (235.385 KB) | DOI: 10.20527/jbk.v17i2.11674

Abstract

Abstract: As many as 7 – 12% of the world's population has chronic kidney disease (CKD). CKD patients can experience various complications, one of which is anemia. Anemia can cause a variety of cardiovascular complications in CKD patients. Enforcement of the diagnosis of anemia and its type is carried out by laboratory examination, among others by examination of reticulocytes-hemoglobin (ret-he) and iron status such as serum ferritin. Examination of these parameters can help in planning the right treatment for CKD patients who have anemia. The purpose of this study was to determine the relationship of Ret-he with ferritin levels in CKD patients undergoing hemodialysis at PKU Bantul Hospital. This study used cross-sectional method. The data source used was secondary data obtained from medical records and the Indonesian Renal Registry (IRR). Sampling research used consecutive sampling method. The analysis used univariate analysis which was frequency distribution table, and bivariate analysis. Univariate analysis obtained that average levels of ret-he from 50 subjects was 28.87 ± 3.75 pg and median serum ferritin levels were 118,1 (9,76 – 1615) mL. Bivariate analysis with pearson correlation test found a significant correlation between serum ret-he and ferritin levels (r = 0.498, p = 0.000).There was a significant correlation between he-ret levels and serum ferritin levels Keywords: chronic kidney disease, anemia, reticulocytes-hemoglobin, serum ferritin.
CORRELATION BETWEEN THE PERCENTAGE OF HYPOCHROMIC ERYTHROCYTES AND FERRITINE LEVELS IN CHRONIC KIDNEY DISEASE PATIENTS UNDERGOING HEMODIALYSIS IN PKU BANTUL HOSPITAL Seno Dwi Prasetyo; Linda Rosita; Utami Mulyaningrum
Berkala Kedokteran Vol 18, No 1 (2022)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.132 KB) | DOI: 10.20527/jbk.v18i1.12843

Abstract

Abstrak: The incidence of CKD in the world is more than 500 million patients and up to 1.5 million patients need to undergo renal replacement therapy in the form of hemodialysis. Chronic kidney disease is inseparable from several complications, one of which is anemia. Confirmation of the diagnosis of anemia in CKD patients can be confirmed through various examinations such as the classic examination of serum ferritine levels, but ferritine is known to be involved in the inflammatory process that occurs in CKD. The aims of this study were to determine the relationship between the percentage of hypochromic erythrocytes and ferritine levels, to determine the average percentage of hypochromic erythrocytes and to determine the average ferritin level in CKD patients undergoing hemodiliasis at PKU Bantul Hospital. This study was conducted using a cross-sectional method involving 50 CKD patients at PKU Bantul Hospital. Blood samples were taken to check ferritine levels and hypochromic erythrocyte percentage. Data analysis was carried out with two types, univariate analysis and bivariate analysis which were carried out with the Spearman correlation test. Based on the results of univariate analysis, the median percentage of hypochromic erythrocytes of the research subjects was 0.95%. The median ferritine in research subjects was 105.5 ng/mL. based on the results of bivariate analysis, there was no significant relationship between the percentage of hypochromic erythrocytes and ferritine levels (p=0.130, r=-0.217). There was no significant relationship between the percentage of hypochromic erythrocytes and ferritine levels. Keywords: anemia; ferritine serum, chronic kidney disease, reticulocytes hemoglobin
Sistem Inferensi Fuzzy untuk prediksi Sindrom Metabolik bagi penyandang Penyakit Ginjal Kronik Muhammad Zainudin Al Amin; Sri Kusumadewi; Linda Rosita
JATISI (Jurnal Teknik Informatika dan Sistem Informasi) Vol 8 No 3 (2021): JATISI (Jurnal Teknik Informatika dan Sistem Informasi)
Publisher : Lembaga Penelitian dan Pengabdian pada Masyarakat (LPPM) STMIK Global Informatika MDP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35957/jatisi.v8i3.1032

Abstract

Patients with Chronic Kidney Disease (CKD) are increasing every year. One of the risk factors is due to metabolic syndrome because components in the metabolic syndrome are the cause of risk factors for CKD. The purpose of this study is to build a fuzzy inference system to predict metabolic syndrome for people with CKD. The method in this research is through literature study in building fuzzy rules and forming a fuzzy inference system. The variables used are body mass index, blood pressure, triglycerides, HDL and fasting blood sugar. System testing was carried out on eight hemodialysis patient data. The results of the system test are able to provide information related to the percentage of metabolic syndrome risk levels in 7 patients with chronic kidney disease.
sUrVEI tUrN ArOUND tIME PADA PELAYANAN LABORATORIUM Linda Rosita; O Sianipar
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 13, No 3 (2007)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v13i3.916

Abstract

Turn Around Time (TAT) is time analysis check the laboratory started by since acceptance sampel still result and inclusive of result which have validated marked with the signature of laboratory doctor. TAT represents the important shares from medical service promisedTAT represents the important shares from medical service promised by laboratory party. Evaluate the TAT started from analysis to equipment of admission filling of request form of inspection laboratory.Evaluate the stuffing of request form met from the condition of sampel and telephone number which can be contacted nothing that filled. sampel and telephone number which can be contacted nothing that filled. and telephone number which can be contacted nothing that filled. TAT of better outpatient from at TAT of at patients take care. The monitoring of TAT shall have the character of the continue and ableThe monitoring of TAT shall have the character of the continue and able to give the feed back so that quality of good laboratory service progressively.
DIFFERENCES IN CHANGES OF HEMOGLOBIN BETWEEN 6-12 HOURS AND 12-14 HOURS AFTER TRANSFUSION Rosita Linda; Devita Ninda
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 24, No 2 (2018)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v24i2.1306

Abstract

Each year more than 41,000 blood donations are needed every day and 30 million blood components are transfused. Blood products that can be transfused include Packed Red Cells (PRC), Whole Blood (WB), Thrombocyte Concentrate (TC), Fresh Frozen Plasma (FFP). Monitoring Hemoglobin (Hb) after transfusion is essential for assessing the success of a transfusion. The time factor after transfusion for Hemoglobin (Hb) examination needs to be established, analyze to judge the success of a blood transfusion which is performed. The aim of this study was to analyze the differences in changes of hemoglobin between 6-12 hours, and 12-24 hours after-transfusion. This study was retrospective observational using secondary data. The subjects were patients who received PRC, and WBC transfusion. At 6-12, and 12-24 hours after-transfusion, hemoglobin, RBC, and hematocrit were measured. Then the data were analyzed by unpaired t-test. The collected data included the results of the Hb pre-transfusion, 6-12, and 12-24 hours after-transfusion. The subjects of this study were 98 people. The administration of transfusion increased by 10-30% in hemoglobin concentration at 6-12 hours after-transfusion. While at 12-24 hours after-transfusion, hemoglobin after-transfusion increased 15-37% from the baseline. Hemoglobin values were not different at any of the defined after-transfusion times (p = 0.76 (p>0.05)). Hemoglobin values were not different at 6-12 hours, and 12-24 hours after-transfusion.    Keywords: Hemoglobin, measurement, after-transfusion 
STATUS PENGGUMPALAN (AGREGASI) TROMBOSIT SEBAGAI FAKTOR PROGNOSTIK TEJADINYA KELUARAN KLINIS STROK INFARK MENDADAK (STROK INFARK AKUT) Linda Rosita; Usi Sukorini; Budi Mulyono
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 17, No 2 (2011)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v17i2.1021

Abstract

The propriate management of acute infarction stroke will be able to reduce the morbidity and mortality of the disease. In diagnosingand managing the diseases, for the detection of the risk or prognostic factors information’s such as the history physical findings,confirmation and other supporting tests are needed. One of the supporting test is the laboratory examination i.e. platelet aggregationtest. Platelet aggregation is suggested having an important role in haemostasis especially to prevent excessive bleeding by forming plateletplug. Finally, further hyperactivity of platelet in terms of platelet hyper aggregation can create a thrombus and moreover lead to obstructthe vessels. The occlusion will give a negative outcome of an acute infarction stroke. The aim of this study is to know whether platelethyper aggregation has a contribution in the outcome of the disease or not by certain testing. A prospective cohort study was carried out,to compare between two groups of exposed and non-exposed group in Sardjito hospital Yogyakarta during the period of March up toearly July 2007. Eighty four subjects who met the inclusion and exclusion criteria were involved in this study. The exposed group was agroup of acute infarction stroke patient who were exposed to platelet hyper aggregation 48 (57%), on the other hand, patients who didnot have platelet hyper aggregation was separated as non-exposed group is 36 (43%). Inception of cohort was applied when the patientwas admitted to the emergency unit during 72 hours of the onset, before receiving antithrombotic drugs and had no previous history ofstroke. The patients were followed after 7 days hospitalization in the stroke unit and neurology unit and the outcome was measured byevaluating the score using Gadjah Mada stroke scale. The characteristics of the subjects were grouped by baseline data X2 test. Unvariedanalysis and multivariate analysis were taken to get the relative risk of having acute infarction stroke. In this case logistic regressionanalysis was used to know the relative risk (RR) measurement. Prognostic factors had influenced the outcome of acute infarction strokein patients who had a history of cardiovascular disease and aggregation status. The outcome of the platelet hyper aggregation grouphad a RR=2.15 (95% CI: 2.01–4.07) and the history of cardiovascular disease had a RR=1.78 (95% CI: 1.18–13.28).
HUBUNGAN DISLIPIDEMIA DAN KEJADIAN PENYAKIT JANTUNG KORONER Rian Ma’rufi; Linda Rosita
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 6, No 1, (2014)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol6.Iss1.Art7

Abstract

Latar Belakang Penyakit jantung koroner (PJK) merupakan penyebab kematian utama di dunia. Penelitian lain yang dilakukan sebelumnya memberikan hasil bahwa dislipidemia merupakan faktor risiko tersering penyakit jantung koroner. Tujuan Tujuan penelitian ini untuk mengetahui hubungan antara dislipidemia (LDL) dan kejadian penyakit jantung koroner pada penderita di RS PKU Muhammadiyah Yogyakarta periode 1 Januari 2010 – 31 Desember 2011. Penelitian ini menggunakan desain cross-sectional, dan pengambilan sampel menggunakan metode konsekutif sampling. Subyek penelitian adalah laki-laki dan perempuan yang berumur lebih dari 45 tahun dan mempunyai data profil lipid yang lengkap. Subyek penelitian dibagi menjadi 2 kelompok, 32 subyek dengan penyakit jantung koroner dan 32 subyek tanpa penyakit jantung koroner. Analisis data dilakukan menggunakan uji chi-square. Hasil Persentase pasien dengan kadar LDL >130 mg/dL pada kelompok PJK adalah 65,6% dan pada kelompok non-PJK adalah 40,6% (p=0,045 dan RP=1,68; 95% CI=1,01-7,7). Kesimpulan Penelitian ini menunjukkan hasil bahwa kadar LDL >130mg/dL berhubungan dengan faktor risiko kejadian penyakit jantung koroner pada subyek penelitian Kata kunci : Penyakit jantung koroner, dislipidemia, LDL
Pengaruh Suhu dan Interval Waktu Penyimpanan Sampel Serum pada Pengukuran Kadar Glukosa Darah Onne Degita Santi; Linda Rosita; Yeny Dyah Cahyaningrum
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 3, No 8, (2011)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The number of samples should be checked often can not be done immediately examination due to the limited number of laboratory personnel. This phenomenon is common in clinical laboratories and private land. This needs attention given the many factors that can affect test results. Pre-analytical factors that need to be considered is the examination time interval and sample storage temperature prior to examination. Examination of blood glucose is one of the frequent checks at the hospital. The method often used is glucose oxidase method with the serum as a sample. The purpose of this research is todetermine how far the impact of delays in the inquest and the influence of storage temperature on serum blood glucose levels. The study was conducted on 30 people consisting of patients and hospital employees who are willing. Criteria for inclusion were men or women aged 20 - 40 years old and willing to follow the research. Exclusion criteria were suffering from diabetes, severe kidney disease, or are pregnant. Each subject and blood samples taken as soon as possible done on a blood sample centrifugation to obtain serum. Serum from each sample was divided into 3 tubes, which will be examined: immediate and delayed 4 hours and each tube is stored at a temperature of 2-8 °C and 25-28°C. The parameters examined were the blood chemistry of blood glucose. Examination of blood glucose using glucose oxidase method. Sampling is performed by the method of consecutive (consecutive sample). Statistical analysis by independent samples t-test. The examination of serum samples from 30 patients and hospital employees who meet the criteria of inclusion and exclusion. Comparison of results of blood glucose levels at examination time delay between 0 hours and 4 hours to get results that are not significant (p>0.05). And blood glucose levels between groups of temperature 25-28 °C and 2-8 °C no significant difference in outcome (p>0.05). The interval 0 hour storage time and 4 hours at a temperature of 25- 28 °C (room temperature) and 2-8 °C (refrigerator temperature) does not affect the results of bloodglucose levels in serum samples.
PERBEDAAN PERUBAHAN KADAR KOLESTEROL TOTAL DAN TRIGLISERID ANTARA PEMAKAIAN MONOTERAPI INSULIN DENGAN TERAPI KOMBINASI INSULIN DAN METFORMIN PADA PASIEN DIABETES MELITUS TIPE II Prita Murani Nugraheti; Erlina Marfianti; Linda Rosita
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 10, No 1, (2019)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol10.Iss1.art3

Abstract

Backround: Diabetes mellitus (DM) is a degenerative disease predicted by WHO to increase in Indonesia from 8.4 million in 2000 to around 21.3 million in 2030. Diabetes mellitus is closely related to dyslipidemia which can increase the risk of coronary artery disease (CAD). Current DM treatment is using oral hypoglycemic drugs, insulin, or a combination of both. Many previous studies have not examined the effect of these therapies on lipid profiles, specifically total cholesterol and triglyceride levels.Objective: To determine the differences in changes in total cholesterol and triglyceride levels between the use of insulin monotherapy and combination therapy of insulin and metformin in patients with type II diabetes mellitus in Sleman Yogyakarta Hospital from January 2010 toJune 2012.Methods: This study was an observational analytic study using a retrospective cohort study method with samples (n = 64). Samples were taken by non-probability consecutive sampling, carried out in DM patients inpatient or outpatient at Sleman Yogyakarta Hospital for the period of January 2010 - June 2012. The samples were divided into two groups, insulin monotherapy group and insulin and metformin combination therapy group. The data taken was the total cholesterol and the first triglyceride level, then the second total cholesterol and triglyceride data were made after four months of getting therapy.Result: Analysis of statistical data using the Mann Whitney test for changes in total cholesterol levels in the two treatment groups showed p = 0.166, whereas for changes in triglyceride levels in the two treatment groups it was found that p = 0.840.Conclusion: There were no significant differences in changes in total cholesterol and triglyceride levels between the two treatment groups.
Prolonged severe acute respiratory syndrome of Corona Virus-2 positive with polymerase chain reaction: A case report Linda Rosita; Rahma Yuantari; Budi Mulyono; Umi Solekhah Intansari; Ingesti Bilkis Zulfatina
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 11, No 3, (2020)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol11.Iss3.art12

Abstract

COVID-19 continues to spread across the world, with more than 60 million confirmed cases in 220 countries. Since March 11, 2020, WHO announced the COVID-19 outbreak as a pandemic. Impacts caused by COVID-19 are not only on the health sector but also economic, social, and political sectors. In a diagnosing process, the SARS-CoV-2 PCR results for swab specimen are a gold standard in determining confirmed COVID-19 cases. Previously, 2 repeated results of negative SARS-CoV-2 PCR become criteria of being recovered from COVID-19. Therefore, based on the latest guidelines from the Indonesian Ministry of Health revised on July 13th 2020, patients with no symptoms, mild to moderate symptoms, and severe symptoms are declared to be recovered if the patients meet the requirements of finished periods of isolation based on a doctor’s assessment. Confirmed cases with severe or critical symptoms are specially declared with one negative result of the PCR test plus three days without showing any symptoms. This case study discussed a 52-years-old woman diagnosed with COVID-19. PCR test for this patient had been conducted 11 times during 64 days of treatment, and its results turned to be always positive, failing to fulfil the discharge criteria. Therefore, it needs to determine causes of prolonged positive PCR results and impacts of clinical condition of the patients, and prognosis of the patients.
Co-Authors Abd. Halim Adika Zhulhi Arjana Al Amin, Muhammad Zainudin Arofiq, Muhammad Ariq Naufal Asri Hendrawati Budi Mulyono Budi Mulyono Chanifah Indah Ratnasari Cita Auli Nisa Devita Ninda Elyza Gustri Wahyuni Erlina Marfianti, Erlina Ester Tri Rahayu Farida Juliantina Rachmawaty Ingesti Bilkis Zulfatina Irfan, Mohammad Rozan Irfan, Rozan Muhammad Izzati Muhimmah Juwariyah Juwariyah Juwariyah Juwariyah Jwitaningsih, Tita Khairul Hafidh Malfica, Muhammad Joddy Maryani Saputri, Eka Muhammad Salman Shalahuddin Mulyaningrum, Utami Nisa, Cita Auli O Sianipar Onne Degita Santi Pembantjanawati, Endah Permana, I Gede Surya Prita Murani Nugraheti Rahayu, Ester Tri Rais, Andri Rian Ma’rufi Rositasari, Annisa Rozan Muhammad Irfan Seno Dwi Prasetyo Setyawati Setyawati Siregar, Raudatul Hasanah Sri Kusumadewi Sri Mulyati Sukma Puspitorini Supardianto Supadianto Syaefudin Ali Akhmad Usi Sukorini Utami Mulyaningrum Yeny Dyah Cahyaningrum Yuantari, Rahma