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All Journal Jurnal Sains dan Teknologi Pangan Jurnal Sains Teh dan Kina Jurnal Ilmiah Farmako Bahari Jurnal Pengabdian Masyarakat DEDIKASI Jurnal Ilmiah Farmasi Simplisia Jurnal Medika Farmaka Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Ardi Rustamsyah
Sekolah Farmasi Institut Teknologi Bandung
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology Nursing Public Health

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POTENSI TANAMAN YANG MEMILIKI AKTIVITAS TERHADAP PROPIONIBACTERIUM ACNES : Systematic Riview: POTENSI TANAMAN YANG MEMILIKI AKTIVITAS TERHADAP PROPIONIBACTERIUM ACNES : Systematic Riview Muharam, Firman; Rahman Nugraha, Yogi; Mamay, Mamay; Rustamsyah, Ardi; Azzahra, Nazwa Aleefha; Sabila, Muthia Nafisa Nur; Fadilah, Astrid Julian; Ramadani, Alya Suci; Aulia Rahma, Devi
Jurnal Medika Farmaka Vol 3 No 3 (2025): Vol 3 No 3 (2025): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v3i3.90

Abstract

Introduction: Acne (acne vulgaris) is an inflammatory skin disorder commonly experienced by adolescents and adults, with Propionibacterium acnes being the primary bacterium responsible for the inflammation. Increasing antibiotic resistance and the side effects of synthetic drugs have encouraged the use of herbal plants as a safer antibacterial alternative. Objective: This review aims to identify herbal plants that have antibacterial activity against P. acnes, as well as to evaluate the extraction methods, test methods, and inhibition zone effectiveness reported in studies from 2020–2025. Methods: The article was developed through a literature review using Google Scholar with the keywords “activity test,” “plant,” and “P. acnes.” The data analyzed included plant type, extraction technique, testing method, and antibacterial activity results. Results: Maceration with ethanol is the most common extraction method, while antibacterial tests often use disc diffusion and well diffusion. Plants such as bay leaves (Syzygium polyanthum), starfruit leaves (Averrhoa bilimbi), red betel leaves (Piper crocatum), and a combination of pineapple leaves and green betel leaves showed strong inhibition zones (20–24 mm). Guava leaves also provided high activity, while jasmine flowers and porang frog showed weak activity. Conclusion: This study shows that several herbal plants, such as bay leaves, starfruit leaves, and red betel leaves, have strong antibacterial activity against Propionibacterium acnes, while others showed less effectiveness. These results confirm that certain herbal plants have the potential to be developed as natural antibacterials for acne treatment, although further research is needed to determine their mechanism of action, safety, and optimal formulation.
Co-Authors . Elfahmi Ai Kholisoh, Ai Anita Kahirunnisa Asep Darda darul hikam Aulia Rahma, Devi Azzahra, Nazwa Aleefha Dadan Rohdiana Dani Sujana Elvi Trinovani, Elvi Elvi Trinoviani, Elvi Fadilah, Astrid Julian Farid Permana Fauziah, Nenden Firman Muharam Ilahi, Resa Restu Isti Agnia Lutfiah, Isti Agnia Komar Ruslan Wirasutisna Kusumah, Raden Minda Lubis, Novri Yanti Mamay, Mamay Martiani, Isye Mimin Kusmiyati, Mimin Nisa Fitriani Ar-Rifa, Nisa Fitriani Nurazizah, Siska Perdana, Farid Puspitasari, Tien Ellita Endah Rahman Nugraha, Yogi Ramadani, Alya Suci Rhamadianto, Muhamad Iqbal Sabila, Muthia Nafisa Nur Sarah Nur Islami, Sarah Nur Yayat Sudaryat Yoga Yuniadi Yogi Rahman Nugraha Zulfakor, Dava