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All Journal VALENSI Alchemy : Journal of Chemistry JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Ilmu Kefarmasian Indonesia Pharmaceutical And Biomedical Sciences Journal (PBSJ)
Sabrina Dahlizar
Program Studi Farmasi, Fakultas Ilmu Kesehatan, UIN Syarif Hidayatullah Jakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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Journal : Alchemy : Journal of Chemistry

 1 
Pemetaan Komponen Metabolit Sekunder Utama dari Tanaman Berkhasiat terhadap Paru paru menurut Al-Qanun fi at-Tibb 2 karya Ibnu Sina djamain, nelly suryani; Nurkholiza, Zahara Faiziah; Saibi, Yardi Yardi; Betha, Ofa Suzanti; Dahlizar, Sabrina Sabrina; Dillasari, Estu Mahanani
ALCHEMY:Journal of Chemistry Vol 12, No 1 (2024): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v12i1.21469

Abstract

Al-Qanun fii at-Tibb 2 is a medical text book by Ibn Sina, which contains monographs of various natural materials, especially plants that have properties for organs including the lungs. In this book there is no data regarding the secondary metabolite content of these plants and this study aims to conduct a literature review of the main secondary metabolite components of these plants. and see the correlation between the major components and their efficacy on the lungs. This research was conducted using the literature review method through various databases by extracting from 124 scientific journals information about 58 plants that are efficacious for lung organs according to Al Qanun Fi'l Tibb and data has been produced in the form of the content of the main secondary metabolites of these plants, namely flavonoids, terpenes, tannins, lignans., saponins, anthraquinones, glucosinolates, phenolic acids, sekoiridoids, steroids, and alkaloids as the major components. Based on the results of this review, the main components of secondary metabolites are known to have reported beneficial bioactivities in the treatment of the respiratory system and lung organ.
Pengaruh Karbopol dan Propilen Glikol terhadap Laju Penetrasi Sediaan Emulgel Xanthone Rich Fraction dari Kulit Buah Manggis (Garcinia mangostana L.) Dahlizar, Sabrina; Alifia Agustina, Putri; Fitriana, Narti; Wira Septama, Abdi; Fajriah, Sofa; Herdini, Herdini
ALCHEMY:Journal of Chemistry Vol 11, No 2 (2023): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v11i2.20520

Abstract

Xanthone Rich Fraction (XRF) derived from mangosteen rind (G. mangostana L.) contains α-mangostin possessed antioxidant property. It may be used to prevent aging (anti-aging). This study aims to determine the effect of adding Carbopol as a gelling agent and propylene glycol as an enhancer on the physical characteristics and penetration rate of the emulgel. Four different formulas were prepared, F1 without a gelling agent (Carbopol) and enhancer (propylene glycol), F2 without a gelling agent (carbopol), F3 using a gelling agent (carbopol), and F4 using a gelling agent (carbopol) and enhancer (propylene glycol). The physical properties of formulas such as organoleptic examination, pH, viscosity, homogeneity, spreadability and cycling test were evaluated. Penetration testing was carried out using a Franz Diffusion cell. The results showed that F3 and F4 had the best physical stability and there was a difference in the penetration rate of α-mangostin from the four formulas. The amount of α-mangostin expanding the area for 6 hours, F1, F2, F3 and F4 were 228,22 µg/cm2; 251,06 µg/cm2(Tabel 3); 852,24 µg/cm2; dan 1.087,15 µg/cm2 respectively. The addition of a combination of Carbopol (gelling agent) and propylene glycol (enhancer) showed the highest penetration rate
Co-Authors Abdi Wira Septama Akhsani, Luthfia Wikhdatul Alfian Noviyanto Alifia Agustina, Putri Anwar, Vidia Arliani Azzahra, Afifah Nurnishrina Berti Puspitasaril Betha, Ofa Suzanthi Djamain, Nelly Suryani Effionora Anwar Estu Mahanani Dhilasari Herdini , Herdini Komala, Ismiarni L B S.Kardono LBS Kardono Mahliga Dwi Rezky Putri Maulina Handayani Munfarikhatin, Atina Narti Fitriana, Narti Nelly Suryani Novitri, Suci Ahda Nurkhasanah Nurkhasanah Nurkhasanah Nurkhasanah Nurkholiza, Zahara Faiziah Ofa Suzanthi Betha Ofa Suzanti Betha Putri Kurniasih Putri Kurniasih RAHMAT, DENI Saibi, Yardi Yardi Sofa Fajriah Suci Ahda Novitri Supandi Supandi Vini Almira Wira Septama, Abdi Yardi Yardi Yuni Anggraeni Zilhadia Zilhadia