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All Journal JURNAL KIMIA SAINS DAN APLIKASI Jurnal Fisika Unand Jurnal Riset Kimia IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Jurnal Zarah Indonesian Journal of Chemistry Akta Kimia Indonesia Molekul: Jurnal Ilmiah Kimia JFIOnline Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Hydrogen: Jurnal Kependidikan Kimia Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES) Jurnal Katalisator Riset Informasi Kesehatan Molekul: Jurnal Ilmiah Kimia Borneo Journal of Pharmacy Jurnal Kimia Unand
Adlis Santoni
Jurusan Kimia, Universitas Andalas, Padang, 25163, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Profil Fitokimia dan Penentuan Fenolik Total, Flavonoid Total, dan Uji Aktivitas Antioksidan Ekstrak Daun Sungkai (Peronema canescens Jack) dari Daerah Kota Padang Adlis Santoni; Mai Efdi; Fadhillah, Nurul
Jurnal Kimia Unand Vol. 12 No. 1 (2023): May 2023
Publisher : Departemen Kimia Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jku.12.1.1-6.2023

Abstract

Sungkai (Peronema canescens Jack) is a plant that is easy to find in Indonesia. Sungkai leaves are used by the community as herbal medicine to boost immunity. The purpose of this study was to determine the phytochemical profile, total phenolic content and total flavonoids and test the antioxidant activity of Sungkai leaf extract. Sungkai leaf extract was obtained by maceration method in stages. The results of the phytochemical screening showed that ethyl acetate extract and methanol extract contained phenolic and flavonoid compounds. Total phenolic test using the method Folin-Ciocalteu with the highest total phenolic content in methanol extract namely 172.75 mg GAE/g sample. Total flavonoid test using the AlCl3 method with the highest total flavonoid content in the ethyl acetate extract, namely 825.714 mg QE/g sample. Antioxidant activity test using the ABTS method with a very strong antioxidant activity in methanol extract with IC50 of 13.589 mg/L.
Isolasi dan Karakterisasi Senyawa Triterpenoid dari Ekstrak Etil Asetat Daun Salam (Syzygium polyanthum (Wight) Walp.) serta Uji Sitotoksik Menggunakan Metode BSLT (Brine Shrimp Lethality Test) Ferdinal, Norman; Muhamad Fadli; Rizki Septiardi; Adlis Santoni
Jurnal Kimia Unand Vol. 12 No. 1 (2023): May 2023
Publisher : Departemen Kimia Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jku.12.1.7-13.2023

Abstract

   The bay plant (Syzygium polyanthum (Wight) Walp.) is a member of the myrtaceae family. The most widely used part of the bay plant is the bay leaf. The leaves of this plant are often used as traditional medicine to treat gout, diarrhea, diabetes, and high blood pressure. This study aims to isolate and determine the characteristics of triterpenoid compounds from ethyl acetate extract of bay leaves. Isolation was carried out by column chromatography method with SGP (Step Gradient Polarity) elution system, then the isolated compound was purified by recrystallization method and obtained in the form of white crystals weighing 0.0188 g. TLC results showed a single purple spot after being treated with Liebermann Buschard reagent with a melting point range of 137-139 oC. The results of the UV spectrum data showed no conjugated double bonds and the results of the FTIR spectrum data showed the presence of hydroxyl groups, C-O alcohols, C-H alkanes, C=C alkenes, geminal dimethyl which are characteristic of triterpenoid compounds. Cytotoxic activity testing was carried out using the Brine Shrimp Lethality Test (BSLT) method.  Ethyl acetate extract and methanol extract had strong cytotoxic activity with LC50 values 316.23 mg/L and 234.42 mg/L respectively, while the hexane extract was weak with an LC50 value of 1148.15 mg/L.
PENENTUAN KANDUNGAN FENOLIK TOTAL, SIFAT ANTIOKSIDAN DAN TOKSISITAS DARI EKSTRAK KULIT BATANG RENGAS (Gluta renghas L.) Salim, Emil; Santoni, Adlis; Febriana, Nindi Antika
Jurnal Zarah Vol. 8 No. 2 (2020): October, 2020
Publisher : Fakultas Keguruan dan Ilmu Pendidikan, Universitas Maritim Raja Ali Haji

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31629/zarah.v8i2.2416

Abstract

Tujuan penelitian ini untuk menentukan jumlah kandungan fenolik total, sifat antioksidan dan toksisitas dari ekstrak kulit batang rengas (Gluta renghas L.). Sampel kulit batang rengas diekstraksi secara bertahap menggunakan pelarut n-heksan, etil asetat dan metanol pada temperatur ruang. Jumlah kandungan fenolik total ditentukan dengan metode Folin-Ciocalteau, sifat antioksidan ditentukan dengan metode DPPH (1,1-diphenyl-2-pycrilhydrazil), dan sifat toksisitas ditentukan dengan metode BSLT (Brine Shimp Lethality Test). Ekstrak metanol kulit batang rengas memiliki kandungan fenolik total paling tinggi (20,042 mg GAE/g ekstrak kering) dibandingkan ekstrak etil asetat dan n-heksan. Sifat antioksidan dari ekstrak metanol dan etil asetat tergolong sangat kuat dengan nilai IC50 12,252 mg/L dan 48,151 mg/L secara berturut-turut, sedangkan ekstrak n-heksan besifat lemah dengan nilai IC50 206,06 mg/L. Sifat toksisitas kulit batang rengas menunjukkan bahwa semua ekstrak bersifat toksik, dimana ekstrak metanol memiliki sifat toksisitas paling kuat dengan nilai LC50 54,113 mg/L. Senyawa aktif dari ekstrak kulit batang rengas ini selanjutnya dapat dilakukan isolasi untuk mengetahui strukturnya.
Co-Authors -, Sabariah Afif, Iffat Syafiqoh Afrizal Afrizal Aisya, Nurul Akmel Suhada Anggraini, Anna Anggriany, Martania Asri Amelia Bumali, Restu Bustanul Arifin BUSTANUL ARIFIN Bustanul Arifin Bustanul Arifin Daimon Syukri Darwir, Djaswir Darwir, Djaswir Deswati Deswati Djaswir Darwis Elisabet Elisabet Emil Salim Emriadi Emriadi - Fadhillah, Nurul Fajarandi, Nabiel Febriana, Nindi Antika Frisky, Sintia Harfita, Nur Laily Hazli Nurdin Hazli Nurdin Hermansyah Aziz Imelda Indah Putri Lestari Intania Permata Khoiriah Khoiriah Kurniawan, Yayan Rabbani Leidina Zein Mai Efdi Mai Efdi Matlal Fajri Alif Muhamad Fadli Nabiel Fajarandi Nindi Antika Febriana Norman Ferdinal Novesar Jamarun Novesar Jamarun Novesar Jamarun Nurul Fadhillah Nurul Hanifah Olly Norita Tetra Raden Mohamad Herdian Bhakti Rahmi Vika Ulia Ria Januarti Ridho Sahary Adha Rizki Septiardi Rizki Septiardi Sabariah - Safni Safni Salim, Emil Sari Ramadhani Silfani Mairanti Siti Aisyah Sjamsul A Achma Sjamsul A. Achmad Sjamsul A. Achmad Suhada, Akmel Suhada, Akmel Suryati Suryati Suryati Suryati Suryati Syukri - Syukri Arief Syukri Arief Syukri Syukri Triranti, Bunga Mainur Trisno Afandi Vanny Yulia Safitri Wellia, Diana Vanda Yayan Rabbani Kurniawan Yelfira Sari Yetria Rilda Yoan De Nanda Herru Yulizar Yusuf Yulizar Yusuf Yunazar Manjang Yunazar Manjang Zilfa Zilfa