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All Journal JURNAL HUTAN LESTARI Jurnal Entropi Syntax Jurnal Informatika Bimbingan dan Konseling Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan Jurnal Pilar Nusa Mandiri Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) Indonesian Journal of Science and Mathematics Education GHIDZA: Jurnal Gizi dan Kesehatan JURIKOM (Jurnal Riset Komputer) Jurnal Pengabdian UNDIKMA Journal of Public Health Innovation (JPHI) Jurnal Kebidanan Manna International Journal of Business and Applied Economics (IJBAE) Prosiding Dedikasi: Pengabdian Mahasiswa Kepada Masyarakat Jurnal of Islamic Economic Studies IJIS Edu : Indonesian Journal of Integrated Science Education
Eka Puspita Sari
Fakultas Kehutanan Universitas Tanjungpura. Jalan Imam Bonjol 78124
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Potential of avocado oil (Persea americana) in improving triglyceride and High Density Lipoprotein (HDL) levels in rats (Rattus novergicus) model of dyslipidaemia due to high fat diet Sari, Eka Puspita; Wasita, Brian; Muthmainah, Muthmainah
Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) VOLUME 12 ISSUE 4, 2024
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/ijnd.2024.12(4).296-305

Abstract

Background: Elevated levels of Dyslipidaemia pose a significant threat to cardiovascular health. Fortunately, the abundance of polyunsaturated and monounsaturated fatty acids (PUFA and MUFA) present in avocado oil offers a promising avenue for individuals with Dyslipidaemia to improve their lipid profile levels.Objectives: The objective of this research is to ascertain the potential of avocado oil in improving triglyceride and HDL levels.Methods: A pre-post test control group design was employed, utilizing male Wistar rats aged 8 weeks with a body weight ranging from 150-200 g. The mice were segregated into six groups: N, K-, K+, P1, P2, and P3. Throughout the trial, solely group N abstained from ingesting avocado oil or HC. Conversely, all other groups were administered HC and subsequently, K+ was prescribed simvastatin while P1, P2 and P3 received avocado oil for a duration of 28 days. The data was subjected to statistical analysis using SPSS vr.25. The statistical significance threshold was set at p<0.05.Results: Mean changes in levels (mg/dL) for TG -29.67 (P1), -48.99 (P2), -56.78 (P3) and for HDL 41.75 (P1), 46.35 (P2). There was a significant difference in TG and HDL levels between P1, P2, P3 when compared with K- (p<0.05).Conclusion: Avocado oil exhibits efficacy in lowering TG levels and elevating HDL levels, rendering it a viable option for daily consumption.
Co-Authors Ahmad Zaini Aliansyah, Dimas A. Brian Wasita Budiastutik , Indah Chairul Anwar Chairul Anwar Chuswarany, Muzdalifah P. Dedy Miswar Dosinaeng, Antonius S.W. Duwiri, Devega E. Elly Trisnawati Enri, Ultach Evy Wardenaar Fathul Yusro Fennyria, Dolis Yesti Fermata, Widya Fifi Yasmi Fitria Kasih Gunina, Offelani C. Gusnidarsih, Vevi Indah Budiastutik Indra Permana, Indra Irwandani Irwandani Isman, Ainul Fatha Marlenywati Marlenywati Miswanto Miswanto Muhamad, Arief Mulyani, Astriana Muthmainah Muthmainah Nawipa, Nova J.R.K Netty Ino Ischak Nopiya, Ninin Nukhbatul Bidayati Haka NUR AINI Nurhayati Bialangi Panji Maulana, Mohammad Pargito Pargito Pekei, Amelia Y. Pereira, Deolindo Henrique Pureklolon, Paula S.M PURWANTI PURWANTI Rahmarianti, Gusni Ridwan, Fahri Sarmento, Tito Apolinario Sasarari, Anisa H.N. Supriyadi Supriyadi Tabuni, Alfian B.F.C Tantu, Nur R.N.A BT Usman Tasik, Putri I. Titi Solfitri Uduas, Karmila Ulandari, Cantika Fania Wanimbo, Ofrida Yarisetouw, Orpa I. Yenita Roza