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All Journal IJOG : Indonesian Journal on Geoscience Biology, Medicine, & Natural Product Chemistry Media Penelitian Pendidikan : Jurnal Penelitian dalam Bidang Pendidikan dan Pengajaran ALCHEMY Jurnal Penelitian Kimia IT JOURNAL RESEARCH AND DEVELOPMENT Journal of Dedicators Community CARADDE: Jurnal Pengabdian Kepada Masyarakat MATRIK : Jurnal Manajemen, Teknik Informatika, dan Rekayasa Komputer Indonesian Journal of Community Services Community Empowerment Didaktika: Jurnal Kependidikan Practice of The Science of Teaching Journal: Jurnal Praktisi Pendidikan Depik Jurnal Ilmu-Ilmu Perairan, Pesisir dan Perikanan Proceeding International Conference on Digital Education and Social Science
Mega Novita
Universias PGRI Semarang
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Public Health Social Sciences Other

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Formulation and Evaluation of Spirulina-Based Gel with Varying Carbopol Concentrations for Anti-Acne Activity against Staphylococcus epidermidis Emmellia Yunitha; Anita Nilawati; Mega Novita; Dian Marlina
Biology, Medicine, & Natural Product Chemistry Vol 14, No 2 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.142.699-705

Abstract

Spirulina platensis is a blue-green microalga known for its antibacterial properties, offering potential as a natural alternative in acne treatment. Acne vulgaris, often caused by Staphylococcus epidermidis, requires effective topical solutions. Gels are favored for their non-greasy texture, ease of application, and good skin absorption. This study aimed to formulate and evaluate anti-acne gels containing 25% Spirulina extract with varying Carbopol concentrations (0.5%, 1%, 1.5%). Each formulation was assessed for physical properties, stability over 21 days, and antibacterial activity against S. epidermidis. All gel formulations met quality standards for pH, homogeneity, viscosity, spreadability, and adhesiveness. The gel with 0.5% Carbopol (FI) showed the best spreadability, ideal viscosity, and good adhesiveness, along with the highest antibacterial activity, exhibiting an inhibition zone of 16.5 mm—comparable to tetracycline. In conclusion, Spirulina-based gel with 0.5% Carbopol offers an effective, stable, and natural anti-acne option. These findings highlight the potential of Spirulina as a bioactive agent in topical formulations and encourage further research for clinical applications in acne management.
Analysis of water quality in watershed using heavy metal pollution index Rizky Muliani Dwi Ujianti; Mega Novita; Aan Burhanuddin; Iffah Muflihati; Lukman Anugrah Agung; Roies Nur Ingsan; Alfan Najihil Wafa; Cerly Nurlita Anggraeni; Tsaqif Muzakki
Depik Vol 13, No 2 (2024): AUGUST 2024
Publisher : Faculty of Marine and Fisheries, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13170/depik.13.2.35680

Abstract

The quality of rivers and coastal is gradually deteriorating along with rapid population and socio-economic growth in the watershed to the estuary. Sampling was conducted in Semarang city rivers and Demak district rivers, Central Java Province, Indonesia, at four different stations according to geography and designation: river basins, estuaries, and rivers affected by industrial and domestic waste. Research time is August - October 2023 during the dry season. The research method uses descriptive analysis to determine the variables to be studied based on the research results in the field. River and coastal pollution levels are measured using the Heavy Metal Pollution Index method, with several water quality parameters measured, such as BOD, COD, Ammonia, TDS, TSS, and Total Coliform. In contrast, the heavy metal parameters measured are Cd, Ni, Zn, Cu, and Pb. The heavy metals and water quality parameters analyzed guided by Government Regulation of the Republic of Indonesia Number 22 of 2021 class 2. Water quality and heavy metal analysis use the Heavy Metals Pollution Index (HPI). HPI is an assessment method that shows the influence of individual heavy metal compounds on overall water quality. The results show that the status of non-metal water quality in terms of HPI analysis shows that Sampling Station (SS) 1 is 224.30 (unsuitable for drinking), SS 2 is 645.98 (unsuitable for drinking), SS 3 is 320.09 (unsuitable for drinking), SS 4 is 252.09 (unsuitable for drinking), and metal parameters in terms of HPI analysis show that SS1 is 26.43 (good), SS2 is 2345.84 (unsuitable for drinking), SS3 is 26.43 (good), and SS4 is 12.64 (excellent). The conclusions from these four research areas indicate that the status of water quality, according to the HPI is unsuitable for drinking, however, indications of heavy metals in 2 areas are still tolerable, namely good and excellent. The decline in water quality in the research area is caused by domestic and industrial waste polluting the waters. In conclusion, this river area requires further management from the collaboration of various stakeholders.Keywords:Water QualityHeavy MetalCoastalWatershed
Co-Authors Aan Burhanuddin Abdillah Fathan Generus Annajah Achmad Buchori Alfan Najihil Wafa Aris Tri Jaka Harjanta, Aris Tri Bambang Agus Herlambang, Bambang Cerly Nurlita Anggraeni Desi Purwaningsih Dian Ayu Azhari Diva Julia Paramita Dola Mareta Anggarini Emmellia Yunitha Fafa Nurdyansyah Febrian Murti Dewanto Fenny Roshayanti Haryo Kusumo Haryo Kusumo Hayat, Muhammad Syaipul Hery Widijanto I Nyoman Adi Putra Iffah Muflihati Iffah Muflihati Iffah Muflihati, Iffah Joko Setyawan Katarina Herwanti Khoirya Latifah Laelia Puti Aditasar Lukman Anugrah Agung Marlina, Dian Mujiono Mujiono Nila Kusumaningtyas Nilawati, Anita Nugroho Dwi Saputro Nur Khoiri Nurdiyati Nurfiana Rachmawati Retno Setianingsih Rifki Hermana Rifki Hermana Rina Widyawati Rizky Muliani Dwi Ujianti Rizky Muliani Dwi Ujianti Rizky Muliani Dwi Ujianti Roies Nur Ingsan Saptono Nugrohadi Saptono Nugrohadi Senowarsito Senowarsito Senowarsito, Senowarsito Shindi Nofitasari Siti Aisiyah Siti Nurlaela Setianingsih Sri Wahyuni Stanislaus Christo Petra Nugraha Sudargo Sudargo Sukma Nur Ardini Sutomo Sutomo Sutomo Sutomo Sutomo Sutomo Sutomo Sutomo Tsaqif Muzakki Waliyansyah, Rahmat Robi Yuris Setyoadi