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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Pengabdian UntukMu NegeRI JSFK (Jurnal Sains Farmasi & Klinis) JURNAL PHOTON Jurnal Pengabdian Magister Pendidikan IPA JURNAL FARMASIMED (JFM) Jurnal Farmasi Indonesia AS-SHIHA: JURNAL KESEHATAN Journal Of Pharmacy
Hari, Dewi Gulyla
Department Of Pharmacy, Faculty Of Health And Natural Sceiences, Universitas Muhammadiyah Riau
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary

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Workshop Kartu Kuartet dan Donasi Buku di Panti Asuhan Darul Ilmi Pekanbaru Dewi Gulyla Hari; Yasinda Oktariza; Muhammad Azhari Herli
Jurnal Pengabdian UntukMu NegeRI Vol 5 No 1 (2021): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jpumri.v5i1.2499

Abstract

Sebagai penyambung generasi muda di masa yang akan datang, pendidikan harus diberikan dengan baik pada anak sejak dini. Pendidikan yang baik dapat dimulai dengan meningkatkan kemampuan dan minat baca anak karena membaca adalah jendela dunia. Lemahnya kemampuan dan minat baca anak dapat memengaruhi kualitas anak dalam mengikuti perkembangan ilmu pengetahuan dan informasi selama menempuh pendidikan. Maka dari itu, Program Kemitraan Masyarakat Stimulus (PKMS) ini bertujuan untuk dapat meningkatkan minat baca dan pengetahuan anak-anak di Panti Asuhan Darul Ilmi Pekanbaru. Program PKMS dilakukan dengan tiga kegiatan utama yaitu peningkatan minat baca melalui donasi buku bacaan anak, peningkatkan pengetahuan anak melalui penyuluhan obat dan workshop kartu kuartet anti penyalahgunaan obat, serta evaluasi minat baca dengan metode observasi dan evaluasi tingkat pengetahuan anak-anak panti dengan menggunakan kuesioner. Berdasarkan hasil observasi, donasi buku bacaan anak dapat meningkatkan minat anak untuk membaca karena buku yang diberikan sesuai dengan usia dan kebutuhan anak-anak yang ada di panti asuhan. Penyuluhan dan workshop kartu kuartet juga menunjukkan adanya peningkatan skor rata-rata antara sebelum dan setelah pelaksanaan penyuluhan obat dan workshop kartu kuartet. Hal ini menunjukkan minat baca dan pengetahuan anak-anak panti asuhan mengalami kenaikan setelah penyelenggaraan program PKMS ini.
Implementation of pharmacy delivery services in the era of digital and pandemic Covid-19 Dewi Gulyla Hari; Yasinda Oktariza; Ayu Rahmawati
Pharmaciana Vol 12, No 1 (2022): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v12i1.20127

Abstract

The Covid-19 pandemic has had a significant impact on changes in people's behavior which currently prefer online ordering in order to implement social distancing and physical distancing. This study aims to see the behavior of pharmacy customers in using delivery services during the pandemic and strategies that can be used to attract customers to return to using delivery service. This study is an observational analytic study conducted at CV. Apotek Keluarga in the period October-December 2020. A total of 149 respondents were involved in this study. Customer behavior was observed by collecting information from customers as well as profiles of requests for delivery services from January to August 2020. Analysis of strategies to attract customer interest in shopping again at the pharmacy was carried out by looking at the correlation of the factors that influence the intention to return through distributing questionnaires. The demand profile for delivery services shows an increase in demand during pandemic in March 2020 from 22.92% to 94.35%. The results of the bivariate analysis show that there is a significant correlation on each variable score for trust, checkout satisfaction, after-delivery satisfaction, and price perception on the intention to return. The results of the multivariate analysis show that the variables, independently correlated with intention to return were trust variables with a weak positive correlation coefficient (r = 0.210), after-delivery satisfaction with sufficient positive correlation coefficient (r = 0.306), and price perception with sufficient positive correlation coefficient (0.434). Based on the results of this study, it can be concluded that the application of delivery services at pharmacies has the opportunity to be applied during the Covid-19 pandemic period as well as after the pandemic. Pharmacies need to build trust, satisfaction, and good price perceptions for customers to attract customers to return to using home delivery at pharmacies.
Identifikasi Type Human Papillomavirus (HPV) pada Penderita Kanker Serviks Marlina Marlina; Yufri Aldi; Andani Eka Putra; Densi Selpia Sopianti; Dewi Gulyla Hari; Arfiandi Arfiandi; Akmal Djamaan; Rustini Rustini
Jurnal Sains Farmasi & Klinis Vol 3, No 1 (2016): J Sains Farm Klin 3(1), November 2016
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (337.511 KB) | DOI: 10.29208/jsfk.2016.3.1.100

Abstract

Human Papillomavirus (HPV) is the most significant risk factor for the cause of cervical cancer. The purpose of this study for identification of HPV types 16, 18, 31, 33, 45 and 52 in cervical cancer patients. HPV is a row of high-risk HPV types that can cause cervical cancer. Total sample of 78 diisolat DNA derived from FFPE, cervical smears and cervical cancer fresh tissue obtained from Dr. Dr. M. Djamil, Padang and hospitals. Arifin Achmad, Pekanbaru. HPV DNA detection is done by using Polymerase Chain Reaction (PCR) using universal primers GP5 +/6 +. HPV types were identified by PCR with specific primers. Total sample types obtained with concentrations varying between 0.9 to 645 ng / ml with purity DNA in accordance with the specified purity for PCR amplification. The results of the study of 78 patients with cervical cancer samples, 42 samples (54%) identified HPV DNA. HPV type 18 is more dominant and followed by HPV type 16 as compared to the other types, namely the percentage of 40.4% and 28.5%. HPV type 45 (7.1%), HPV type 52 (2.3%) and HPV 31 and HPV type 33 was not detected.
Identifikasi Gen E7 Isolat Human Papillomavirus Tipe 18 (HPV18) dari Penderita Kanker Serviks Arfiandi Arfiandi; Densi Selpia Sopianti; Dewi Gulyla Hari; Marlina Marlina; Yufri Aldi; Andani Eka Putra; Akmal Djamaan; Rustini Rustini
Jurnal Sains Farmasi & Klinis Vol 3, No 1 (2016): J Sains Farm Klin 3(1), November 2016
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (326.463 KB) | DOI: 10.29208/jsfk.2016.3.1.95

Abstract

Gen E7 HPV18 merupakan salah satu onkoprotein yang selalu diekspresikan oleh HPV pada sel yang terinfeksi. Infeksi persisten oleh Human papillomavirus (HPV) beresiko tinggi adalah faktor etiologi utama untuk kanker serviks dan ekspresi Onkoprotein HPV E7 disarankan untuk menjadi penanda potensial untuk perkembangan tumor. E7 akan mempengaruhi aktivitas pRB supresor tumor serta mengikat dan mengaktifkan kompleks cyclin sehingga dapat menimbulkan kanker serviks. Dalam penelitian ini akan dilakukan identifikasi terhadap Gen E7 isolat HPV18 dari penderita kanker serviks yang berasal dari RSUP M. Jamil Padang, Sumatera Barat dan RSUD Arifin Ahmad, Pekan Baru, Riau. Proses identifikasi dilakukan dengan metode Polymerase Chain Reaction (PCR) menggunakan primer spesifik untuk gen E7 HPV18. Dari lima belas isolat HPV18 yang diamplifikasi dengan primer spesifik gen E7 HPV18, didapatkan sepuluh sampel positif teridentifikasi gen E7 (66,6%) sedangkan lima sampel lainnya tidak teridentifikasi. Infeksi kanker pada penderita kanker serviks yang berasal dari RSUP. M. Jamil, Padang dan RSUD. Arifin Ahmad, Pekan Baru, Riau sebagian besar disebabkan oleh gen E7 HPV18 sehingga hal ini bisa dijadikan penanda potensial untuk perkembangan tumor bagi penderita kanker serviks di Sumatera Barat dan Riau pada khususnya serta di Indonesia pada umumnya.
Evaluasi Penggunaan Obat Antihipertensi Primer Pasien Lanjut Usia Periode Januari – Juni 2022 Di Puskesmas Minas Ayu Rahmawati; Dewi Gulyla Hari; nisa, Annisa Nurul Maharani
The Journal Of Pharmacy Vol. 1 No. 1 (2023): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Abstract

Hipertensi adalah keadaan seseorang yang mengalami peningkatan tekanan darah di atas normal, yaitu tekanan darah sistolik ≥ 140 mmHg dan atau tekanan darah diastolik ≥ 90 mmHg. Tujuan penelitian ini adalah untuk mengetahui ketepatan penggunaan obat antihipertensi primer dan hubungan Sosiodemografi terhadap hasil pengobatan pasien di Puskesmas Minas periode januari – juni tahun 2022. Metode yang digunakan adalah metode deskriptif dengan rancangan non ekperimental. Data penelitian diperoleh dari berkas catatan medik yang dikumpulkan dengan teknik pengumpulan secara purposive sampling dengan jumlah sampel sebanyak 110 pasien yang berusia lanjut. Pada hasil penelitian ini menunjukkan data karakteristik pasien yang paling banyak yaitu jenis kelamin perempuan sebesar 69 orang (62,7%), kelompok usia 45-59 tahun 53 orang (48,2%), pasien yang tidak bekerja 81 orang (73,6), dan golongan obat yang banyak digunakan yaitu amblodipin sebesar 107 pasien (97,2%). Pada hasil uji chi-square dengan nilai kemaknaan p value = 0,05 terhadap hubungan umur dan jenis kelamin terhadap faktor resiko didapatkan nilai umur adalah p = 0,873 sedangkan jenis kelamin memiliki nilai p = 0,000. Disimpulkan bahwa evaluasi penggunaan obat antihipertensi di Puskesmas Minas sudah 100% tepat dan menunjukkan bahwa umur dengan faktor resiko tidak memeliki hubungan, sedangkan jenis kelamin dengan faktor resiko memeliki hubungan. Untuk penelitian lebih lanjut diharapkan dapat melakukan observasi terhadap 2 tempat atau lebih sebagai pembanding untuk hasil yang lebih bervariatif.
Penetapan Kadar Flavonoid Total Ekstrak Etanol 96% Daun Gaharu (Aquilaria malaccensis Lam) dengan Spektrofotometer UV-Vis Indriani, Lusi; Dewi Gulyla Hari; Arabella Natasya; Nurdina Putri
The Journal Of Pharmacy Vol. 2 No. 1 (2024): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Abstract

Gaharu leaves (Aquilaria malaccensis Lam) are a type of plant commonly used as a raw material for pharmaceuticals, cosmetics, and perfumes due to its secondary metabolic compounds such as flavonoids, alkaloids, terpenoids, steroids, and quinones. This study aims to determine the total flavonoid content of 96% ethanol extract of gaharu leaves using UV-Vis spectrophotometry. Gaharu leaves were extracted using the Microwave-Assisted Extraction (MAE) method with 96% ethanol as the solvent. The resulting extract was then qualitatively tested and the flavonoid content was measured using UV-Vis spectrophotometry with quercetin as the standard. The results of the determination of the total flavonoid content of the 96% ethanol extract of gaharu leaves were 2.539 ± 0.005% equivalent to quercetin.
Desain Primer PCR Sebagai Biomarker COVID-19 Strain Terbaru Yang Di Identifikasi Di Januari 2021 Herli, Muhammad Azhari; Hari, Dewi Gulyla; Rahmawati, Ayu
Photon: Jurnal Sain dan Kesehatan Vol. 11 No. 2 (2021): Jurnal Photon
Publisher : LPPM Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jp.v11i2.3645

Abstract

Coronavirus disease 2019 (COVID-19) is a contagious disease caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS CoV-2). The disease first spread in Wuhan, Hubei Province, China in December 2019. SARS-CoV-2 is highly contagious and has grown rapidly around the world since its discovery. Until January 2021, a total of 101,406,059 confirmed cases of SARS-CoV-2 infection worldwide with a death toll of 2,191,898 and still growing. Diagnosis of COVID-19 is carried out in two common ways, namely a rapid test and PCR (polymerase chain reaction). This study aims to design a PCR primer for the latest COVID-19 strain isolated in January 2021 with the insilico method (computer simulation) so that the primer used as a COVID-19 biomarker is fast and accurate. The results of this study obtained 10 of the best primers from the latest COVID-19 strains with codes MW454767, MW454771, MW460582, MW454660 which were identified on 11 Jan 2021.
Aktivitas Antidiabetes Ekstrak Daun Gaharu (Aquilaria malaccensis Lam) Dan Daun Binahong (Anredera cordifolia) Pada Mencit Jantan Lusi Indriani; Dewi Gulyla Hari; Sari Ramadhani; Nurdina Putri; Siti Niqmatun Jannah
The Journal Of Pharmacy Vol. 2 No. 2 (2025): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Abstract

The binahong plant (Anredera cordifolia) is known to contain active compounds such as alkaloids, flavonoids, saponins, tannins, and terpenoids that have the potential to lower blood glucose levels. This study aimed to evaluate the antihyperglycemic activity and determine the optimal dose of the combination of ethanol extract of agarwood (Aquilaria malaccensis) leaves and binahong leaves in male mice. The study was conducted experimentally using a Completely Randomized Design (CRD) using 25 mice divided into five treatment groups: a negative control (0.05% NaCMC) and a positive control (metformin). The other three groups were given a combination of agarwood and binahong extracts in dosage ratios of 1:1, 2:1, and 1:2. ANOVA results showed that all extract combinations significantly reduced blood glucose levels compared to the negative control. The 1:1 dose combination showed the best effectiveness, equivalent to metformin, especially on days 3 to 7.
Cytotoxic Activity Testing The Extract of Leaves and Yellow Sirsak Fruit (Annona montana) using Method Brine Shrimp Lethality Test (BSLT) Rahmawati, Noveri; Hari, Dewi Gulyla; Tri Nova Lovena; Nurdina Putri; Rahma Dona; Rahma Cintya Faiza; Amini, Rahmi
The Journal Of Pharmacy Vol. 2 No. 2 (2025): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Abstract

The yellow sirsak plant (Annona montana) is an annonaceae family which has been used by the community as traditional medicine properties such as treating diarrhea, vitamin C deficiency and treating boils. This study aims to determine the cytotoxic activity of the larvae of Artemia salina Leach shrimp by using the BSLT method after giving extracts from the leaves and fruit of yellow sirsak (Annona montana). The results showed that the LC50 value of the n- hexane extract of yellow sirsak leaves was 45,84 µg/mL, the ethyl acetate extract of yellow sirsak leaves was 26,44 µg/mL and the ethanol extract of yellow sirsak leaves was 13,99 µg/mL. The n-hexane extract of yellow sirsak fruit was 31,46 µg/mL, the ethyl acetate extract was 40,45 µg/mL and the ethanol extract of the yellow sirsak fruit was 19,84 µg/mL. The mixture of n-hexane leaves and yellow sirsak fruit was 29,91 µg/mL, the ethyl acetate extract mixture of yellow sirsak leaves and fruit was 21,71 µg/mL and the mixture of ethanol extract and yellow sirsak fruit was 14,75 µg/mL. Based on the research results, it can be concluded that the ethanol extract of yellow sirsak leaves shows the most active cytotoxic activity with an LC50 value of 13,99 µg/mL.
Penyuluhan Dan Edukasi Obat Bersama Snake Ladder Nurbaiti; Gulyla Hari, Dewi
Jurnal Pengabdian UntukMu NegeRI Vol. 7 No. 2 (2023): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jpumri.v7i2.5037

Abstract

Community service aims to instill wise behavior in using drugs in children from an early age, and improve health, especially in everyday life such as at school and at home. The educational media used in community service is the snake ladder. The use of snakes ladders media is a medium that is easy to understand and learn in providing effective learning. The activity participants were class 2 students of SMP Muhammadiyah 1 Pekanbaru City. The service was carried out by forming small groups consisting of 10 people per group with one instructor. The group will take part in the initial stage, namely the pre test to determine the level of knowledge of students about DaGuSiBu (Can Use, Save and Discard) drugs. The results of counseling using snake ladder media showed an increase in students' knowledge regarding DaGuSiBu medicine. In conclusion, the use of media in DaGuSiBu Medicine counseling at the school children's level is very helpful, so that school children can apply their knowledge in their surroundings. Keywords: Education, Knowledge of medicine, DaGuSiBu, Snake ladder, Effective learning
Co-Authors Akmal Djamaan Amini, Rahmi Andani Eka Putra Arabella Natasya Arfiandi Arfiandi Ayu Rahmawati Ayu Rahmawati AYU RAHMAWATI Densi Selpia Sopianti Densi Selpia Sopianti Encik Juliansyah Arief Hartini, Putri Tri Hendri Sandi, Nofri Herli, Muhammad Azhari Indriani, Lusi Lifiani, Rialita Lusi Indriani M. Azhari Herli Saptadi Putra Marlina . Meirita, Efilia Muhammad Arif nisa, Annisa Nurul Maharani Noveri Rahmawati Novtafia Endri Nurbaiti Nurdin, Khazanah Nurain Nurdina Putri Nursyafni Rahma Cintya Faiza Rahma Dona Rahmi Amini Rustini Rustini Sari Rahmadhani Siti Niqmatun Jannah Tri Nova Lovena Ummul Khairiah Yasinda Oktariza Yasinda Oktariza Yufri Aldi