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ANTI-VIRUS AND BACTERIA MIST TESTING (KAVI-B) TO REMOVE ESCHERICHIA COLI AND STAPHYLOCOCCUS AUREUS BACTERIA Tazi, Imam; Fitriasari, Prilya Dewi; Mulyono, Agus; Noor, Marvina Rizqi; Putri, Siska Emelda
Jurnal Neutrino:Jurnal Fisika dan Aplikasinya Vol 14, No 1 (2021): October
Publisher : Department of Physics, Maulana Malik Ibrahim State Islamic University of Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/neu.v14i1.15657

A disinfectant and antiseptic vaporizer has been made by using a vibrating membrane in the ultrasonic order. This method does not go through the stages of evaporation by heating the material. This machine is capable of converting ethanol in the liquid phase into the form of mist or vapor very quickly. Within 1 second when the engine is started, the cold ethanol material will turn into steam or mist. The concentration of the ethanol solution after and before evaporation did not change significantly. The change in ethanol concentration that occurs is only around 2-5%. The effect of decreasing colonies of Escerichia coli and Staphylococcus aureus bacteria after being given a mist containing 65% ethanol decreased exponentially. This spray has many advantages over using ethanol in liquid form. The sample size of the vaporized ethanol concentration greatly affects the evaporation produced by the KAVi-B engine. A very linear relationship was found between the concentration and the rate of evaporation. The linear relationship between the concentration of ethanol and the rate of evaporation has a linear regression value of Y = 0.2617X + 20.657 and R2 = 0.9908.

ISOLASI DAN UJI KOMPATIBILITAS BAKTERI HIDROLITIK DARI TANAH TEMPAT PEMROSESAN AKHIR TALANGAGUNG, KABUPATEN MALANG Prilya Dewi Fitriasari; Nanda Amalia; Susiyanti Farkhiyah
BERITA BIOLOGI Vol 19, No 2 (2020)
Publisher : Research Center for Biology-Indonesian Institute of Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14203/beritabiologi.v19i2.3828

Talangagung landfill, Malang Regency has used the controlled landfill method. The landfill process produces methane gas that has been flowed as fuel so that it is estimated that there are bacteria with a variety of enzymatic activities that have worked in degrading waste. The purpose of this study was to isolate bacteria from landfill and determine the ability to produce amylase, protease, lipase, and cellulase and test the compatibility of bacteria. The methods used include bacterial isolation using the pour plate method and purification of bacterial isolates using the streak plate method. Bacterial selection is done on selective media containing starch, tributyrin, cellulose, and skim milk. There were 21 bacterial isolates successfully isolated 13 consisting of bacterial isolates showed proteolytic activity, 10 cellulolytic bacteria, 8 amylolytic, and 15 lipolytic. The isolates that show compatible results are BTA 5.7.14, BTA 5.7.7, BTA 5.7.12, and BTA 5.7.6 therefore they can be used as a potential consortium for organic waste recycle.

Immunomodulatory Activity of Allium sativum, Curcuma mangga, and Acorus calamus Combination Nanoparticle on Mice Leukocytes Profile Bayyinatul Muchtaromah; Nur Izzah Analisa; Mujahidin Ahmad; Prilya Dewi Fitriasari; Soraya Habibi; Alfiah Hayati; Ely Nuril Fajriyah
Jurnal Biodjati Vol 7, No 1 (2022): May
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v7i1.11879

Immunomodulators are substances acting as stimulants or suppressants against the immune system, either to specific or non-specific activity. The non-specific through the production of leukocytes as the first response in fighting against an attacking antigen. Meanwhile, the specific, hrough recognition of antigens by lymphocytes during reattack. This research aimed to determine the immunomodulatory activity of the extracts combination nanoparticles of Allium sativum, Curcuma mangga, and Acorus calamus on the leukocyte profile of mice. This study used 5 treatments and 6 repetitions. The treatment groups were K- (untreated group), P1 (extracts combination nanoparticle dose of 25 mg/kg), P2 (extracts combination nanoparticle dose of 50 mg / kg), P3 (subur kandungan herbal medicine dose of 75 mg / kg), and P4 (Clomiphene citrate dose of 0.9 mg / kgBW). The parameters used included the total number of leukocytes and their differential value. The data that met the parametric assumptions, such as normally distributed and homogeneous were examined using the One Way ANOVA test, and when there was a significant difference, it was processed with the Duncan assessment. While those that did not meet the assumptions were evaluated using a non-parametric analysis. The statistical results showed that administration of extracts combination nanoparticles of A. sativum, C. mangga, and A. calamus at doses of 25 mg/kg and 50 mg/kg were able to suppress the inflammatory reaction by decreasing the total number of leukocytes. However, the differential leukocyte count was able to maintained or modulate immune system, indicating by the percentage of neutrophil, basophil, and eosinophil in the normal range. At a dose of 50 mg/kg, decreased the percentage of lymphocytes, while for monocytes, all dosage ranges were able to increase their number.

Pelatihan Pembuatan Nata de Coco pada PKK di Tasikmadu, Lowokwaru, Kota Malang Ulfah Utami; Liliek Harianie; Nur Kusmiyati; Prilya Dewi Fitriasari
Jurnal Pengabdian Pada Masyarakat Vol 5 No 1 (2020)
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/002.202051.268

TRAINING ON MAKING NATA DE COCO FOR PKK ORGANISATION IN TASIKMADU, LOWOKWARU, MALANG CITY. One of the functional food products is nata. Nata is a collection of cellulose which has a chewy texture, white, producing gel sheets that float on the liquid surface. Material that is often used as a medium for making nata is coconut water, known as Nata de Coco. Acetobacter xylinum bacteria are added in the process of making nata de coco on steril condition. The process is important to be informed to the community, in particular the PKK organization through community development program. The methods used include lectures, practice and evaluation. Survey of partners showed that 23,8% had known the process of making nata de coco while 76,2% had not known the process, through this training, 68% partners strongly agree nata production is used as a business idea.

PELATIHAN PEMBUATAN PUPUK BOKASI UNTUK MENDUKUNG PERTANIAN ORGANIK DI SMKN 1 WONOSARI MALANG Nur Kusmiyati; Ulfah Utami; Prilya Dewi Fitriasari; Muhammad Asmuni Hasyim; Fitriyah Fitriyah; Azizatur Rahmah
Jurnal Abdimas Bina Bangsa Vol. 3 No. 2 (2022): Jurnal Abdimas Bina Bangsa
Publisher : LPPM Universitas Bina Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46306/jabb.v3i2.250

Community service activities regarding training in making bokasi fertilizers were carried out at SMKN 1 Wonosari Malang to be carried out to support organic farming. The purpose of this service activity is to provide knowledge about making bokasi fertilizers in supporting organic farming efforts. These service activities are carried out using several methods consisting of outreach; demonstrations and practices; guidance followed by mentoring; as well as an analysis of the evaluation of the service program. This training was attended by 30 participants consisting of class XII students at SMKN 1 Wonosari, Malang Regency. Based on the results of the questionnaire data analysis, it can be seen that the knowledge of the participants about bokasi fertilizers in an effort to support organic farming has increased, after participating in training activities; participants are able to make bokasi fertilizer; there is a change in the pattern of knowledge related to bokasi fertilizer so that participants can plan to produce bokasi fertilizer. Overall, it can be said that the training program for making bocation fertilizer in an effort to support organic farming is running effectively and is able to change the knowledge and abilities of students at SMKN 1 Wonosari, Malang Regency

Effect of Chitosan-Coated Centella asiatica Nanoparticles on Kidney Histology Profile of Complicated Diabetic Mice Bayyinatul Muchtaromah; Ana Mar'a Konita Firdaus; Eko Budi Minarno; Prilya Dewi Fitriasari; Mei Rhomawati; Maharani Retna Duhita; Wira Eka Putra
Jurnal Biodjati Vol 8, No 2 (2023): November
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v8i2.21430

Gotu kola (Centella asiatica) is a medicinal plant that has potential as an antioxidant and antidiabetic. Its compound is able to protect against diabetic nephropathy through the inhibition of oxidative stress. In terms of increasing drug potency and bioavailability of C. asiatica compounds, nanoparticle technology was used. This study aimed to determine the effect of C. asiatica nanoparticles coated with chitosan on the renal histology profile of complicated diabetic mice using a completely randomized design (CRD) with five treatment groups and five replications. The treatment groups were divided into K- (the experimental animals were not given any treatment), K+ (the experimental animals were induced by STZ), P1 (STZ + C. asiatica nanoparticles 120 mg/kgBW), P2 (STZ + C. asiatica nanoparticles 180 mg/kgBW), P3 (STZ + C. asiatica nanoparticles 240 mg/kgBW). The experimental animal model of complicated diabetes was induced by intraperitoneal STZ at a dose of 40 mg/kgBW for two days and STZ at a dose of 60 mg/kgBW for three days and then left for nine days. The C. asiatica nanoparticle therapy was given for 28 days. The parameters in this study were the results of scoring cell damage in the glomerular and tubular tissues (proximal and distal) of the kidney. The data obtained were tested for normality and homogeneity, then the normal and homogeneous data were tested with one-way ANOVA and further tested with Duncan's test. The statistical analysis results showed that C. asiatica coated with chitosan nanoparticles could reduce the damage to the histological profile of the glomerulus and tubules (proximal and distal) of the kidney of diabetic mice. C. asiatica-coated nanoparticles at a dose of 240 mg/kgBW showed the most optimal reduction in damage to the glomerular and tubular histology profiles.

Immunomodulatory Activity of Allium sativum, Curcuma mangga, and Acorus calamus Combination Nanoparticle on Mice Leukocytes Profile Muchtaromah, Bayyinatul; Analisa, Nur Izzah; Ahmad, Mujahidin; Fitriasari, Prilya Dewi; Habibi, Soraya; Hayati, Alfiah; Fajriyah, Ely Nuril
Jurnal Biodjati Vol 7 No 1 (2022): May
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v7i1.11879

Immunomodulators are substances acting as stimulants or suppressants against the immune system, either to specific or non-specific activity. The non-specific through the production of leukocytes as the first response in fighting against an attacking antigen. Meanwhile, the specific, hrough recognition of antigens by lymphocytes during reattack. This research aimed to determine the immunomodulatory activity of the extracts combination nanoparticles of Allium sativum, Curcuma mangga, and Acorus calamus on the leukocyte profile of mice. This study used 5 treatments and 6 repetitions. The treatment groups were K- (untreated group), P1 (extracts combination nanoparticle dose of 25 mg/kg), P2 (extracts combination nanoparticle dose of 50 mg / kg), P3 (subur kandungan herbal medicine dose of 75 mg / kg), and P4 (Clomiphene citrate dose of 0.9 mg / kgBW). The parameters used included the total number of leukocytes and their differential value. The data that met the parametric assumptions, such as normally distributed and homogeneous were examined usingÂ the One Way ANOVAÂ test, and when there was a significant difference, it was processed with theÂ DuncanÂ assessment. While those that did not meet the assumptions were evaluated using a non-parametric analysis. The statistical results showed that administration of extracts combination nanoparticles of A. sativum, C. mangga, and A. calamus at doses of 25 mg/kg and 50 mg/kg were able to suppress the inflammatory reaction by decreasing the total number of leukocytes. However, the differential leukocyte count was able to maintained or modulate immune system, indicating by the percentage of neutrophil, basophil, and eosinophil in the normal range. At a dose of 50 mg/kg, decreased the percentage of lymphocytes, while for monocytes, all dosage ranges were able to increase their number.

Effect of Chitosan-Coated Centella asiatica Nanoparticles on Kidney Histology Profile of Complicated Diabetic Mice Muchtaromah, Bayyinatul; Firdaus, Ana Mar'a Konita; Minarno, Eko Budi; Fitriasari, Prilya Dewi; Rhomawati, Mei; Duhita, Maharani Retna; Putra, Wira Eka
Jurnal Biodjati Vol 8 No 2 (2023): November
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v8i2.21430

Gotu kola (Centella asiatica) is a medicinal plant that has potential as an antioxidant and antidiabetic. Its compound is able to protect against diabetic nephropathy through the inhibition of oxidative stress. In terms of increasing drug potency and bioavailability of C. asiatica compounds, nanoparticle technology was used. This study aimed to determine the effect of C. asiatica nanoparticles coated with chitosan on the renal histology profile of complicated diabetic mice using a completely randomized design (CRD) with five treatment groups and five replications. The treatment groups were divided into K- (the experimental animals were not given any treatment), K+ (the experimental animals were induced by STZ), P1 (STZ + C. asiatica nanoparticles 120 mg/kgBW), P2 (STZ + C. asiatica nanoparticles 180 mg/kgBW), P3 (STZ + C. asiatica nanoparticles 240 mg/kgBW). The experimental animal model of complicated diabetes was induced by intraperitoneal STZ at a dose of 40 mg/kgBW for two days and STZ at a dose of 60 mg/kgBW for three days and then left for nine days. The C. asiatica nanoparticle therapy was given for 28 days. The parameters in this study were the results of scoring cell damage in the glomerular and tubular tissues (proximal and distal) of the kidney. The data obtained were tested for normality and homogeneity, then the normal and homogeneous data were tested with one-way ANOVA and further tested with Duncan's test. The statistical analysis results showed that C. asiatica coated with chitosan nanoparticles could reduce the damage to the histological profile of the glomerulus and tubules (proximal and distal) of the kidney of diabetic mice. C. asiatica-coated nanoparticles at a dose of 240 mg/kgBW showed the most optimal reduction in damage to the glomerular and tubular histology profiles.

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