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All Journal Universa Medicina Jurnal Sains Teknologi dan Lingkungan (JSTL) GIZI INDONESIA Aspirasi : Jurnal Masalah-masalah Sosial Media Penelitian dan Pengembangan Kesehatan
Sudikno Sudikno
Pusat Teknologi Intervensi Kesehatan Masyarakat, Badan Litbangkes, Kemenkes RI, Jl. Percetakan Negara 29 Jakarta
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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HUBUNGAN OBESITAS SENTRAL DENGAN PROFIL LIPID PADA ORANG DEWASA UMUR 25-65 TAHUN DI KOTA BOGOR (Baseline Studi Penyakit Tidak Menular di Kota Bogor, Jawa Barat) Sudikno, Sudikno; Syarief, Hidayat; Dwiriani, Cesilia Meti; Riyadi, Hadi; Pradono, Julianti
GIZI INDONESIA Vol 39, No 2 (2016): September 2016
Publisher : PERSATUAN AHLI GIZI INDONESIA

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Abstract

The global epidemic of obesity is rapidly becoming a major public health problem in many countries of the world. Rapidly changing diets and lifestyles are trigger to the global obesity epidemic. This study aimed to determine the prevalence of central obesity and the relationship between central obesity and lipid profile in adults aged 25-65 years. This study used baseline data "Cohort Study of Non-Communicable Diseases" that was carried out in 2011-2012 in Bogor City, West Java Province. The study design was cross-sectional. A number of samples analyzed were 4554 subjects. Result of the analysis showed that the prevalence of central obesity was found 51.3 percent. The portion of subjects with high total cholesterol levels was 16 percent. The percentage of high LDL cholesterol levels was 17.6 percent. While the portion of low HDL cholesterol levels was 16.2 percent and the portion of high triglyceride levels was 8.5 percent. The results of logistic regression analysis showed that central obesity in adults aged 25-65 associated with lipid profile after controlling the variables of sex, age, and smoking habits. The need for preventive measures to prevent central obesity and abnormal lipid profiles evolve toward disease complications through the fulfillment of adequate daily physical activity and healthy eating habits.
Back matter sudikno, sudikno
GIZI INDONESIA Vol 39, No 1 (2016): Maret 2016
Publisher : PERSATUAN AHLI GIZI INDONESIA

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Back matter 40(1) sudikno, sudikno
GIZI INDONESIA Vol 40, No 1 (2017): Maret 2017
Publisher : PERSATUAN AHLI GIZI INDONESIA

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Front matter sudikno, sudikno
GIZI INDONESIA Vol 39, No 2 (2016): September 2016
Publisher : PERSATUAN AHLI GIZI INDONESIA

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Back matter sudikno, sudikno
GIZI INDONESIA Vol 39, No 2 (2016): September 2016
Publisher : PERSATUAN AHLI GIZI INDONESIA

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Abstract

Front matter 41(1) sudikno, sudikno
GIZI INDONESIA Vol 41, No 1 (2018): Maret 2018
Publisher : PERSATUAN AHLI GIZI INDONESIA

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Abstract

SERUM RETINOL BINDING PROTEIN (RBP) IBU MENYUSUI DAN BAYINYA DI DUA KABUPATEN DI JAWA BARAT Sandjaja, Sandjaja; Sudikno, Sudikno
GIZI INDONESIA Vol 38, No 2 (2015): September 2015
Publisher : PERSATUAN AHLI GIZI INDONESIA

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ABSTRACT Serum retinol concentration is commonly used to determine vitamin A status. Studies show that serum retinol binding protein (RBP) is a surrogate measure of vitamin A. Infant is among groups of high risk in vitamin A deficiency (VAD). Studies show that vitamin A status in lactating mother are associated with that in infant. However, there is no study of association between serum RBP in mother and infant. The objective of this paper is to determine the association of serum RBP in mother and that in infant. The study was conducted at 2 districts in West Java province of 293 pairs lactating mother and breastfed infant aged 6-11 month old of poor families. Serum vitamin A and RBP were measured by HPLC and ELISA respectively. Linear regression was employed to determine association between serum RBP of infant and mother after controlling for other risk factors. Mother’s serum retinol (X+SE) was higher compared to infant (39.0+1.1 and 29.9+0.7 mg/dL). Mother’s serum RBP was also higher in mother than in infant (1.25+0.02 and 0.95 + 0.01 µmol/L). There was a significant association between serum retinol and RBP of mother (r=0.565, p=0.000) and also in infant (r=0.309, p=0.000). There is a significant association between RBP status of mother and infant (r=0.379, p=0.000) controlled by household, mother, and child characteristics. Two main significant factors associated with serum RBP level in infant are serum RBP level of mother (p = 0.000) and infant received high-dose vitamin A capsule (p=0.010). The conclusion is that serum RBP can be used as a surrogate measure of vitamin A status and significant association between serum RBP in lactating mother and her infant. Keywords: retinol binding protein, serum retinol, lactating mother, infant  ABSTRAK Serum retinol umum digunakan untuk menentukan status kurang vitamin A (KVA). Salah satu alternatif menilai KVA adalah serum retinol binding protein (RBP). Beberapa penelitian membuktikan korelasi antara serum retinol ibu menyusui dan bayinya, tetapi belum ada yang meneliti korelasi RBP ibu dan bayinya. Penelitian ini bertujuan untuk mengetahui korelasi serum RBP ibu menyusui dan RBP bayi. Penelitian dilakukan di dua kabupaten di Jawa Barat dengan sampel 293 pasangan ibu menyusui dan bayinya. Serum retinol ditentukan dengan metoda HPLC sedangkan RBP dengan ELISA. Analisis regresi linier digunakan untuk menilai korelasi RBP ibu dan bayi dikontrol dengan faktor risiko lain. Kadar serum retinol (X+SE) ibu menyusui lebih tinggi dibanding bayi (39,0+1,1 and 29,9+0,7 mg/dL). RBP ibu menyusui juga lebih tinggi dibanding RBP bayi (1,25+0,02 and 0,95 + 0,01 µmol/L). Ada korelasi signifikan antara serum retinol dengan RBP baik pada ibu menyusui (r=0,565; p=0,000) maupun pada bayi (r=0,309; p=0,000). Korelasi signifikan dibuktikan antara kadar RBP ibu menyusui dan RBP bayi (r=0,379; p=0,000) dikontrol karakteristik rumahtangga, ibu, dan bayi. Faktor utama yang signifikan menentukan kadar RBP bayi adalah RBP ibu menyusui (p = 0,000) dan bayi menerima kapsul vitamin A 6 bulan terakhir (p=0,010). Serum RBP merupakan alternatif menentukan KVA dan ada korelasi signifikan antara serum RBP ibu menyusui dan bayi.
Back Matter sudikno, sudikno
GIZI INDONESIA Vol 41, No 2 (2018): September 2018
Publisher : PERSATUAN AHLI GIZI INDONESIA

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Abstract

Front Matter sudikno, sudikno
GIZI INDONESIA Vol 41, No 2 (2018): September 2018
Publisher : PERSATUAN AHLI GIZI INDONESIA

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Abstract

High carbohydrate intake increases risk of coronary heart disease in adults: a prospective cohort study Darjoko, Sulistyowati Tuminah; Wahyuningsih, Tri; Sudikno, Sudikno
Universa Medicina Vol 38, No 2 (2019)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (551.069 KB) | DOI: 10.18051/UnivMed.2019.v38.90-99

Abstract

BackgroundCoronary heart disease (CHD) ranks second after diabetes mellitus (DM) based on hazard rate, and after stroke (based on number of deaths caused). Our aim was to determine the risk factor and magnitude of CHD among adults. Methods A cohort study on risk factors of non-communicable diseases (CS-RFNCD) was conducted on subjects aged ≥25 years. Initiated by screening, follow-up (FU) was done 3 times yearly and complete health examination every 2 years. CHD cases screened by electrocardiographic examination on subjects aged ≥40 years and <40 years with history of hypertension and/or heart disease. Screening results found 840 of 5690 subjects with CHD diagnosis who were excluded from cohort study sample. Non-CHD subjects and those aged <40 years without a history of hypertension and/or heart disease, totalling 4840 people, were included in study sample and followed up for 6 years. Data were analyzed using Cox regression.ResultsCarbohydrate intake of ≥60% of total energy had a 2.8-fold higher CHD risk [HR=2.790; 95% CI: 1.962 - 3.967; p=0.000] than that of an intake of <60% of total energy. Age of ≥55 years had 2.6-fold higher CHD risk [HR=2.573; 95% CI: 1.803 - 3.671; p=0.000] than age of <55 years. Blood total cholesterol of ≥200 mg/dL had 1.9-fold higher CHD risk [HR=1.893; 95% CI: 1.319 - 2.715; p=0.001] than that of <200 mg/dL.ConclusionHigher intake of carbohydrate increases CHD incidence among adults. Efforts in controlling CHD risk factors are still needed especially in consumption behavior through a family approach.
Co-Authors Abas B Jahari, Abas B Atmarita Atmarita Cesilia M Dwiriani Ekowati Rahajeng Fitrah Ernawati Gunawan Gunawan Hadi Riyadi Hidayat Syarief Isnaeni, Wilya Julianti Pradono, Julianti Jus'at, Idrus kusnandar kusnandar Kusumaningrum, Farida Moesijanti Soekatri, Moesijanti nFN Sandjaja, nFN Ni Ketut Aryastami Ningsi Ningsi Nur Hafidha Hikmayani Nurjanah, Made Agus Panjaitan, Winda Sauci Rasyid, Irna Sandjaja Sandjaja Sulistyowati Tuminah Darjoko, Sulistyowati Tuminah Suprapti Suprapti Tri Wahyuningsih Wijaya, Ida Bagus Putra Woro Riyadina