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All Journal Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Jurnal Biotek Medisiana Indonesia Universa Medicina GIZI INDONESIA Belitung Nursing Journal Jurnal Kesehatan Tambusai Pharmaceutical Sciences and Research (PSR) Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Woro Riyadina
Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan Republik Indonesia
Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Profit Cedera Akibat Jatuh, Kecelakaan Lalu Lintas dan Terluka Benda Tajam/Tumpul pada Masyarakat Indonesia Riyadina, Woro
Jurnal Biotek Medisiana Indonesia Vol 1, No 1 (2009)
Publisher : Pusat BTDK

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Abstract

Injury contributed to 15% mortality, 25% of disease burden and economic losses 5% GDP (Growth Product Development). Injury from traffic accidents, falls and injured by sharp/blunt object proportion occupied most of the causes of injury in the community, especially in developing countries. Advance analysis aims to compare the profile of injury from falls, traffic accidents and injured by sharp/blunt object on the people of Indonesia. This article is a public health data analysis resulted from 2007 basic health survey interview (Riskesdas) to 928,317 respondents from 33 provinces in Indonesia. The dependent variables were injury from falls, traffic accidents and injured by sharp/blunt object. Independent variables included the body part affected by injury, type of injury and the characteristics of the respondents (gender and type of urban or rural). Analysis of data using complex samples and weighted. Data are analyzed using the Chi square test to different proportions. Results indicated that the most of injury proportion in Indonesia were falls 59.5% (95% CI 58.9 -60.2), traffic accidents (land, sea and air) 27% (95% CI 26.4- 27.5) and injured by sharp/blunt object 18.3% (95% CI 17.7 - 18.9). The majority of the body part affected by injury was the extremities (hand and foot). Type of injury to falls and traffic accidents were supeificial, respectively 54.1% (95% CI 53.2- 54.9) and 65.9% (95% CI 64,9-66,8), meanwhile injured by sharp/blunt object was open wound 63.2% (95% CI 61.9 - 64.6). Order the highest proportion of fracture/amputation were traffic accidents (9.1%), falls (4.6%) and injured by sharp/blunt object (2.3%). As a conclusion that the profile of injury from falls, traffic accidents and injured by sharp/blunt object were different their characteristics. Traffic accident had the highest  severity  of injury (fracture/amputation) so its control needs to get priority.   Keywords: injuries, falls, traffic accidents, injured by sharp/blunt object
Profil keparahan cedera pada korban kecelakaan sepeda motor di Instalasi Gawat Darurat RSUP Fatmawati Riyadina, Woro; Subik, Ita Puspitasari
Universa Medicina Vol 26, No 2 (2007)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2007.v26.64-72

Abstract

Latar belakangProporsi disabilitas dan case fatality rate cedera akibat kecelakaan lalu lintas masih tinggi (25%). Cedera akibat kecelakaan lalu lintas merupakan penyebab utama disabilitas dan mortalitas di negara berkembang. Tujuan penelitian ini adalah untuk menggambarkan profil keparahan cedera yang dialami oleh korban kecelakaan lalu lintas sepeda motor yang masuk ke bagian Instalasi Gawat Darurat Rumah Sakit Umum Pusat (IGD RSUP) Fatmawati.MetodePenelitian ini merupakan bagian dari penelitian “Pengembangan Surveilans Cedera Akibat Kecelakaan Lalu Lintas pada Pengendara Sepeda Motor.” Pengumpulan data dilakukan selama 1 bulan yaitu selama bulan Oktober 2005. Responden adalah pengendara sepeda motor baik sebagai pengemudi maupun penumpang yang mengalami kecelakaan lalu lintas dan masuk ke IGD rumah sakit. Pengumpulan data dilakukan dengan metode wawancara terhadap korban kecelakaan maupun pengantar dengan menggunakan formulir register cedera.Hasil Korban kecelakaan sepeda motor yang masuk ke IGD RSUP Fatmawati selama kurun waktu 1 bulan sebanyak 138 orang. Karakteristik korban adalah mayoritas laki-laki 73,9%, berumur sekitar 21-30 tahun 43,5%, pendidikan setingkat SMU 59,4% dan bekerja sebagai pegawai swasta 55,8%. Kondisi korban yang mengalami cedera ringan sekitar 52,2%, cedera parah 47,8%. Daerah cedera meliputi kepala 55,1% dengan commotio cerebri 6,5%, kaki 12,3% dan lutut/tungkai bawah 9,4%. Jenis luka meliputi luka terbuka 42,0%, patah tulang 18,0% dan luka lecet 14,5%. Faktor-faktor yang berbeda bermakna dengan keparahan cedera adalah waktu terjadinya kecelakaan (malam hari) dan kecepatan kendaraan ³ 60 km/jam (p<0,05).Kesimpulan Korban kecelakaan sepeda motor yang masuk ke IGD RSUP Fatmawati kebanyakan mengalami cedera di bagian kepala dengan luka terbuka, dan kondisi korban yang parah cukup besar yaitu 47,8%.
DETERMINAN OBESITAS PADA WANITA PASCA MENOPAUSE DI KOTA BOGOR TAHUN 2014 Riyadina, Woro; Kodim, Nasrin; Madanijah, Siti
GIZI INDONESIA Vol 40, No 1 (2017): Maret 2017
Publisher : PERSATUAN AHLI GIZI INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36457/gizindo.v40i1.226

Abstract

In Indonesia, the trends of the prevalence of obesity is incresing from year to year, especially in the group of postmenopausal women. Further analysis purposes determine the primary determinant of obesity in postmenopausal women in the city of Bogor A number of samples analyzed 888 postmenopausal women from subset data of research "Risk Factors Cohort Study of Non-communicable Diseases" follow-up of 2 years (2011-2013 and 2012-2014). Data were collected by interview, measurement and examination in 5 villages in the city of Bogor. Obesity is determined based on BMI ≥25. Determinant included demographic, health status and risk behavior. Data were analyzed with multiple logistic regression. The prevalence of obesity in postmenopausal women 57.2 percent. The main determinant of obesity are sufficient levels of carbohydrate aOR 4.6 (95% CI 2.55 to 8.23) than less. Other factors include abnormal hypertriglyceride aOR 3.2 (95% CI 1,85- 4.93) than normal levels, less physical activity aOR 1.6 (95% CI 1.08 to 2.38) than enough activities, the adequacy of excessive protein and family history of obesity with aOR 0.23 (95% CI 0.15 to 0.36) and aOR 0.42 (95% CI 0.28 to 0.61), respectively. Lifestyle modification by limiting carbohydrate intake, walking every day and aerobic exercise at least 1 times a week for one hour and monitor blood triglyceride levels are expected to prevent obesity and decrease overweight. ABSTRAK Di Indonesia, kecenderungan prevalensi obesitas meningkat dari tahun ke tahun, terutama pada kelompok perempuan pasca-menopause. Tujuan analisis lanjut untuk menentukan determinan utama obesitas pada perempuan pasca-menopause di Kota Bogor. Analisis lanjut pada 888 perempuan pasca-menopause yang merupakan subset data penelitian “Studi Kohor Faktor Risiko Penyakit Tidak Menular” follow-up 2 tahun (2011-2013 dan 2012-2014). Data dikumpulkan dengan metode wawancara, pengukuran dan pemeriksaan di 5 kelurahan Kota Bogor tahun 2011– 2014. Obesitas berdasarkan IMT ≥25. Determinan meliputi faktor demografi, status kesehatan dan perilaku berisiko. Data dianalisis dengan uji regresi logistik ganda. Prevalensi obesitas pada perempuan pasca-menopause 57,2 persen. Determinan utama obesitas adalah tingkat kecukupan karbohidrat berlebih aOR 4,6 (95% CI 2,55 – 8,23) dibandingkan kurang. Determinan lain meliputi trigliserida abnormal aOR 3,2 (95% CI 1,85– 4,93) dibandingkan normal, aktivitas fisik kurang aOR 1,6 (95% CI 1,08 – 2,38) dibandingkan aktivitas cukup, tingkat kecukupan protein berlebih dan riwayat keluarga obesitas masing-masing aOR 0,23 (95% CI 0,15 – 0,36) dan aOR 0,42 (95% CI 0,28 – 0,61). Modifikasi gaya-hidup melalui pembatasan asupan karbohidrat, jalan kaki setiap hari dan senam aerobik minimal 1 kali seminggu selama 1 jam serta memantau kadar trigliserida darah diharapkan mencegah dan menurunkan kegemukan. Kata kunci:  determinan, obesitas, pasca-menopause 
SURVIVAL RATE PENYANDANG HIPERTENSI DENGAN KONSUMSI NATRIUM RENDAH TERHADAP KEJADIAN STROKE Rahajeng, Ekowati; Riyadina, Woro
GIZI INDONESIA Vol 39, No 2 (2016): September 2016
Publisher : PERSATUAN AHLI GIZI INDONESIA

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Abstract

Stroke is the leading cause of death and disability in the world. Several studies have shown that stroke can be prevented through modifiable risk factors. The adequate treatment of hypertension may reduce the risk of stroke. Lifestyle modification such as reducing salt intake in hypertension management have demonstrated lowering blood pressure, enhancing the effectiveness of antihypertension drugs and also reducing stroke risk. This study aims to verify the survival rate of hypertension with lower sodium intake (<2000 mg per day) on the incidence of stroke. The study was conducted through a prospective cohort study (4 years of follow-up) in 1082 people with confirmed hypertension. Stroke were confirmed by neurologist. The consumption of sodium, sugar and fat were collected through 24-hour dietary recall. Hypertension survival rate was calculated using Life Table Survival analysis. This study has demonstrated evidence of the higher survival rate of hypertension with low sodium intake on the incidence of stroke, with the difference 2-year survival rate is 3 percent higher and 4-year survival rate is 5 percent higher. Sodium consumption of <2000 mg per day in people with hypertension has prevented a 78 percent incidence of stroke. Therefore, the intervention programs to reduce of the consumption of salt or sodium in Indonesia should be prioritized.
OBESITAS SENTRAL PADA ORANG DEWASA: STUDI KOHOR PROSPEKTIF DI KOTA BOGOR Sudikno, Sudikno; Riyadina, Woro; Rahajeng, Ekowati
GIZI INDONESIA Vol 41, No 2 (2018): September 2018
Publisher : PERSATUAN AHLI GIZI INDONESIA

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Abstract

Central obesity is one of the public health problems in developing countries. This study aims to analyze the dynamic risk factors for central obesity in adults. This study used secondary data "Cohort Study of Non-Communicable Diseases Risk Factors" observing period for six years. The study design was a prospective cohort. The subjects were all household members aged 25 years and above with the criteria remaining in the study area, healthy, non-physically disabled, non-pregnant, having normal abdominal circumference (male ≤ 90 cm and female ≤80 cm) on baseline study, not suffering from non-communicable diseases (hypertension, diabetes mellitus, cancer, stroke, chronic obstructive pulmonary disease) at the baseline of the study, and completeness of the data. The number of subjects at the baseline of the study were 1510, consisting of 613 men and 897 women. The results showed that a cumulative incidence of central obesity during the 6-year observation period of 837 (55.4%). Multivariate cox regression analysis showed that the risk factors for central obesity in adults were gender, age group, marital status, and physical activity. This study concluded that female subjects with physical inactivity had more central obesity compared to male subjects with physical inactivity.ABSTRAK Obesitas sentral merupakan salah satu masalah kesehatan masyarakat di negara berkembang. Penelitian ini bertujuan untuk menganalisis faktor risiko dinamis terjadinya obesitas sentral pada orang dewasa. Penelitian ini menggunakan data sekunder “Studi Kohor Faktor Risiko Penyakit Tidak Menular (FRPTM)” periode pemantauan selama enam tahun. Desain penelitian adalah kohor prospektif. Subjek adalah semua anggota rumah tangga yang berumur 25 tahun ke atas dengan kriteria tetap tinggal di wilayah penelitian, sehat, tidak cacat fisik, subjek perempuan tidak hamil, memiliki lingkar perut normal (laki-laki ≤ 90 cm dan perempuan ≤80 cm) pada awal studi, tidak menderita penyakit tidak menular (hipertensi, diabetes mellitus, kanker, strok, PPOK) pada awal studi, dan kelengkapan data. Jumlah subjek pada awal penelitian 1510 orang, yang terdiri dari 613 laki-laki dan 897 perempuan. Hasil penelitian menunjukkan kumulatif insiden obesitas sentral selama 6 tahun periode pengamatan sejumlah 837 orang (55,4%). Hasil analisis multivariat cox regression menunjukkan bahwa faktor risiko terjadinya obesitas sentral pada orang dewasa adalah jenis kelamin, kelompok umur, status kawin, dan aktivitas fisik. Penelitian ini menyimpulkan bahwa subjek perempuan dengan aktivitas fisik kurang lebih cepat mengalami obesitas sentral dibandingkan subjek laki-laki dengan aktivitas fisik kurang. Kata kunci: faktor risiko, obesitas sentral, dewasa
DETERMINAN OBESITAS PADA WANITA PASCA MENOPAUSE DI KOTA BOGOR TAHUN 2014 Riyadina, Woro; Kodim, Nasrin; Madanijah, Siti
GIZI INDONESIA Vol 40, No 1 (2017): Maret 2017
Publisher : PERSATUAN AHLI GIZI INDONESIA

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Abstract

In Indonesia, the trends of the prevalence of obesity is incresing from year to year, especially in the group of postmenopausal women. Further analysis purposes determine the primary determinant of obesity in postmenopausal women in the city of Bogor A number of samples analyzed 888 postmenopausal women from subset data of research "Risk Factors Cohort Study of Non-communicable Diseases" follow-up of 2 years (2011-2013 and 2012-2014). Data were collected by interview, measurement and examination in 5 villages in the city of Bogor. Obesity is determined based on BMI ≥25. Determinant included demographic, health status and risk behavior. Data were analyzed with multiple logistic regression. The prevalence of obesity in postmenopausal women 57.2 percent. The main determinant of obesity are sufficient levels of carbohydrate aOR 4.6 (95% CI 2.55 to 8.23) than less. Other factors include abnormal hypertriglyceride aOR 3.2 (95% CI 1,85- 4.93) than normal levels, less physical activity aOR 1.6 (95% CI 1.08 to 2.38) than enough activities, the adequacy of excessive protein and family history of obesity with aOR 0.23 (95% CI 0.15 to 0.36) and aOR 0.42 (95% CI 0.28 to 0.61), respectively. Lifestyle modification by limiting carbohydrate intake, walking every day and aerobic exercise at least 1 times a week for one hour and monitor blood triglyceride levels are expected to prevent obesity and decrease overweight. ABSTRAK Di Indonesia, kecenderungan prevalensi obesitas meningkat dari tahun ke tahun, terutama pada kelompok perempuan pasca-menopause. Tujuan analisis lanjut untuk menentukan determinan utama obesitas pada perempuan pasca-menopause di Kota Bogor. Analisis lanjut pada 888 perempuan pasca-menopause yang merupakan subset data penelitian “Studi Kohor Faktor Risiko Penyakit Tidak Menular” follow-up 2 tahun (2011-2013 dan 2012-2014). Data dikumpulkan dengan metode wawancara, pengukuran dan pemeriksaan di 5 kelurahan Kota Bogor tahun 2011– 2014. Obesitas berdasarkan IMT ≥25. Determinan meliputi faktor demografi, status kesehatan dan perilaku berisiko. Data dianalisis dengan uji regresi logistik ganda. Prevalensi obesitas pada perempuan pasca-menopause 57,2 persen. Determinan utama obesitas adalah tingkat kecukupan karbohidrat berlebih aOR 4,6 (95% CI 2,55 – 8,23) dibandingkan kurang. Determinan lain meliputi trigliserida abnormal aOR 3,2 (95% CI 1,85– 4,93) dibandingkan normal, aktivitas fisik kurang aOR 1,6 (95% CI 1,08 – 2,38) dibandingkan aktivitas cukup, tingkat kecukupan protein berlebih dan riwayat keluarga obesitas masing-masing aOR 0,23 (95% CI 0,15 – 0,36) dan aOR 0,42 (95% CI 0,28 – 0,61). Modifikasi gaya-hidup melalui pembatasan asupan karbohidrat, jalan kaki setiap hari dan senam aerobik minimal 1 kali seminggu selama 1 jam serta memantau kadar trigliserida darah diharapkan mencegah dan menurunkan kegemukan. Kata kunci:  determinan, obesitas, pasca-menopause 
HUBUNGAN KONSUMSI KOPI TERHADAP STROK ATAU PENYAKIT JANTUNG KORONER (Baseline Data Studi Kohor Faktor Risiko Penyakit Tidak Menular) Tuminah, Sulistyowati; Riyadina, Woro
GIZI INDONESIA Vol 37, No 1 (2014): Maret 2014
Publisher : PERSATUAN AHLI GIZI INDONESIA

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Abstract

Hubungan antara kebiasaan konsumsi kopi dengan penyakit Strok dan Penyakit Jantung Koroner (PJK) masih menjadi perdebatan apakah bersifat prediktif atau protektif. Tujuan penelitian ini adalah menentukan hubungan antara kebiasaan konsumsi kopi terhadap penyakit Strok atau PJK.  Data merupakan subset dari data baseline penelitian “Studi Kohor Faktor Risiko Penyakit Tidak Menular (FRPTM)” yang diperoleh dengan metode wawancara menggunakan kuesioner dan pemeriksaan kesehatan terhadap penduduk tetap umur 25-65 tahun di 5 kelurahan di Kecamatan Bogor Tengah, Kota Bogor pada tahun 2011-2012 yaitu sebanyak 3.296 responden. Hasil menunjukkan kebiasaan minum kopi bersifat protektif terhadap penyakit Strok atau PJK dengan besaran risiko OR=0,76 (95% CI: 0,64–0,91). Kesimpulan penelitian adalah bahwa kebiasaan minum kopi mempunyai risiko mengalami Strok atau PJK lebih rendah (OR<1) dibandingkan dengan responden yang tidak terbiasa minum kopi setelah dikontrol faktor jenis kelamin dan tekanan darah. Untuk penelitian lebih lanjut disarankan untuk mengkaji jumlah (dosis) kopi yang dikonsumsi orang Indonesia karena data ini sangat dibutuhkan untuk melihat pengaruhnya pada penyakit Strok atau PJK.ABSTRACTHABITUAL COFFEE CONSUMPTION ON STROKE OR CORONARY HEART DISEASE (CHD)(Baseline of Cohort Study on Risk Factors of Non Communicable Disease)  The relationship between habitual coffee consumption on Stroke or Coronary Heart Disease (CHD) is still debatable whether predictive or protective. The objective of the study is  to establish the  association between habitual coffee consumption on stroke or CHD. The analysis used subset data from baseline of cohort study of non communicable disease’s risk factors. Data were obtained through interview method using questionnaire and health examination of 3.296 respondents aged 25-65 years old from five villages in the District of Bogor Tengah, Bogor City in 2011-2012. The result showed that habitual coffee consumption had protective effect on stroke or CHD [OR=0,76 (95% CI: 0,64–0,91)]. It is concluded that  subject who had habitual coffee consumption had a lower risk on stroke or CHD (OR<1) compared to subject who had no habitual coffee consumption after adjusted by sex and blood pressure. Further investigation about different doses of coffee intake according to Indonesian is still needed to see the dose effects to stroke and CHD.Keywords: stroke, coronary heart disease, habitual coffee consumption
Fenomena Pengaruh Terapi Farmakologi Terhadap Kepatuhan Berobat dalam Perspektif Pasien Diabetes Melitus Tipe 2 Renaldi, Fransiskus Samuel; Sauriasari, Rani; Riyadina, Woro; Maulida, Irianti Bahana
Jurnal Farmasi Sains dan Terapan Vol 8, No 2 (2021): Oktober
Publisher : Jurnal Farmasi Sains dan Terapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v8i2.3044

Abstract

Diabetes melitus tipe 2 merupakan penyakit yang kompleks dan membutuhkan manajemen terapi yang serius. Kepatuhan menjadi masalah utama dalam pengobatan diabetes melitus tipe 2 tersebut dan dapat berdampak pada komplikasi yang akan sulit ditangani. Penelitian ini ditujukan untuk mengungkap berbagai permasalahan yang mendorong seorang pasien memilih untuk tidak patuh sehingga dapat membantu tenaga kesehatan dalam mencari akar masalah ketidakpatuhan pada penderita diabetes melitus tipe 2. Sebanyak 30 penderita diabetes melitus tipe 2 terbagi atas beberapa golongan kriteria, yaitu komplikasi, usia, dan tingkat kepatuhan. Pemilihan pasien dilakukan menggunakan metode sampling bola salju. Pengambilan data dilakukan dengan metode wawancara mendalam pada pasien yang dilakukan dengan teknik probing melalui telepon dan observasi langsung sebagai bentuk validasi. Data diolah dengan metode transkrip dan dianalisis secara tematik untuk kemudian diinterpretasikan dalam bentuk pernyataan hasil wawancara. Dari hasil penelitian didapatkan bahwa sebagian besar pasien menggunakan metformin. Hal ini dikarenakan banyak pasien merasa sesuai dengan metformin. Metformin dapat memberikan efek normalisasi gula darah yang diharapkan dengan efek samping ke sistem gastrointestinal yang masih dapat ditolerir. Di sisi lain, terdapat beberapa pasien yang sudah merasa jenuh dengan penggunaan obat secara terus-menerus, mereka ingin segera lepas dari obat. Perbandingan manfaat yang dirasakan ketika meminum obat dan tidak juga turut memotivasi pasien dalam menggunakan obat. Dari berbagai data yang telah dihimpun dalam penelitian ini, dapat disimpulkan bahwa kepatuhan berobat sangat dipengaruhi oleh efek yang diterima pasca penggunaan.
Interpersonal Relationship and Its Effect on Treatment Compliance in Patients with Type-2 Diabetes Mellitus Renaldi, Fransiskus Samuel; Riyadina, Woro; Qamar, Muhammad; Sauriasari, Rani
Pharmaceutical Sciences and Research Vol. 8, No. 1
Publisher : UI Scholars Hub

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Abstract

Type-2 diabetes mellitus has become a chronic disease that can lead to serious complications and can only be prevented by compliant treatment of the patients. Compliance can be influenced by various factors, one of which is interpersonal factors. This study aimed to identify various interpersonal relationship problems between patients and healthcare workers that can affect their treatment compliance behavior. This study employed a qualitative design with phenomenological methods. This research was conducted in Central Bogor City in March-August 2020. The data were collected by conducting in-depth interviews with 20 type-2 diabetes mellitus patients who had been confirmed by the Community Health Center and focus group discussions with 12 healthcare workers consisting of doctors, pharmacists, nutritionists, and nurses. The data were then transcribed and content clouds analysis was carried out. The results showed that most of the patients (76%) followed the advice given by healthcare workers to carry out routine controls. This is a form of patients’ trust in healthcare workers as their health consultants. The trust arises from the convenience of interaction between the two parties. Providing adequate information will increase patients’ understanding and encourage them to take appropriate action for themselves. As many as 12 out of 20 patients chose the Community Health Center for their routine control because the services were sufficient in treating type 2 diabetes mellitus. From this study, it can be concluded that patients tend to comply if they feel trust in the health workers, which arises if they can feel the benefits during their therapy.
The role of changes in metabolic syndrome status on health-related quality of life in Bogor City, West Java, Indonesia: A cross-sectional study Indriyati, Titi; Adisasmita, Asri C.; Nadjib, Mardiati; Subekti, Imam; Hatma, Ratna Djuwita; Kosen, Soewarta; Riyadina, Woro; Purnamasari, Telly
Belitung Nursing Journal Vol. 11 No. 2 (2025): March - April
Publisher : Belitung Raya Foundation, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33546/bnj.3543

Abstract

Background: Metabolic syndrome (MetS) is a cluster of chronic conditions, including central obesity, hypertension, impaired glucose metabolism, and dyslipidemia (low HDL, high LDL, and triglycerides). A diagnosis of MetS is made when three or more of these symptoms are present. If left unmanaged, MetS can lead to serious health complications such as cardiovascular disease and type 2 diabetes. Over time, individuals with MetS may experience a decline in their health-related quality of life (HRQoL), especially due to its chronic nature. Objective: This study aimed to evaluate the effects of changes in MetS status on HRQoL. Methods: This study employed a cross-sectional design. Secondary data from the cohort study of Non-Communicable Disease (NCD) risk factors, conducted by the Health Research and Development Agency of the Ministry of Health of the Republic of Indonesia in Bogor City, was used. Data from four follow-up periods (2011/2012 to 2017/2018) were analyzed. A total of 874 respondents were selected via total sampling based on inclusion and exclusion criteria. Data were collected in 2021, which included measures of knowledge, health check-ups, and HRQoL using the SF-36 questionnaire. Statistical analyses, including chi-square tests, t-tests, and multiple regression analyses, were conducted to examine the associations between MetS status and HRQoL. Results: Descriptive analysis revealed that 19% (171 participants) had worsened MetS status, while 80.4% (703 participants) showed improvement. Chi-Square analysis found that respondents with worsening MetS status were 1.6 times more likely to experience poor HRQoL in the physical dimension (95% CI = 1.1-2.3), but no significant effect was found for the mental dimension (PR = 1.1, 95% CI = 0.8-1.6). Multiple logistic regression analysis revealed that comorbidities interacted with worsening MetS status to significantly affect HRQoL in the physical dimension. The adjusted prevalence ratios (PR) were 27.5 (95% CI = 10.3-73.2) for those with comorbidities and 9.2 (95% CI = 5.7-15.0) for those without comorbidities, after controlling for age, mental health, BMI changes, routine health checks, and knowledge. Conclusion: Changes in MetS status towards worsening have a significant negative effect on HRQoL, particularly in the physical dimension. The presence of comorbidities in individuals with worsening MetS status greatly increases the risk of poor HRQoL. Healthcare professionals and nurses should consider the interaction between MetS and comorbidities in patient management. Nurses are encouraged to monitor HRQoL in patients with MetS, promote education on managing comorbidities, and collaborate across disciplines to enhance patient care and intervention programs aimed at improving HRQoL.
Co-Authors Ajeng Tias Endarti Asri C. Adisasmita Baniu, Ahmad Sahlan Ekowati Rahajeng Febriyanti, Syeri Fitriyani Fitriyani Hatma, Ratna Djuwita Helda Helda Imam Subekti Indriyati, Titi Ita Puspitasari Subik, Ita Puspitasari Maulida, Irianti Bahana Nadjib, Mardiati Nasrin Kodim Panduwiguna, Ivans Pradana Soewondo Prihartono, Nurhayati A Qamar, Muhammad Rani Sauriasari, Rani Ratu Ayu Dewi Sartika Renaldi, Fransiskus Samuel Siti Madanijah Soewarta Kosen Sudarto Ronoatmodjo Sudikno Sudikno Sulistyowati Tuminah Telly Purnamasari