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All Journal Jurnal Ilmu Pertanian Indonesia Jurnal Teknologi Dan Industri Pangan Journal of Food and Pharmaceutical Science Buletin Peternakan VALENSI Jurnal Ilmu Lingkungan AL KAUNIYAH Alchemy : Journal of Chemistry Proceeding International Conference on Global Resource Conservation Elkawnie EduChemia: Jurnal Kimia dan Pendidikan Eksplorium : Buletin Pusat Pengembangan Bahan Galian Nuklir Science and Technology Indonesia Shautut Tarbiyah Al-Kimia Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology Jurnal Ecolab Sulolipu: Media Komunikasi Sivitas Akademika dan Masyarakat Jurnal Riset Sains dan Kimia Terapan al Kimiya : Jurnal Ilmu Kimia dan Terapan Eksplorium : Buletin Pusat Pengembangan Bahan Galian Nuklir
La Ode Sumarlin
Chemistry Study Program, Syarif Hidayatullah State Islamic University, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health Social Sciences Veterinary Other

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Journal : Alchemy : Journal of Chemistry

 1 
Aktivitas Antioksidan Kombinasi Madu Monoflora dengan Ekstrak Daun Namnam (Cynometra cauliflora L.) La Ode Sumarlin; Melina Hadera; Sri Yadial Chalid; Dede Sukandar
ALCHEMY:Journal of Chemistry Vol 6, No 1 (2018): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (517.187 KB) | DOI: 10.18860/al.v6i1.4736

Abstract

Honey and namnam leaves (Cynometra cauliflora L.) have been shown to have antioxidant activity. Combination of both materials potent to be used as functional food. In this study, antioxidant activity of samples was measured by the DPPH method (1,1-diphenyl-2-picrylhydrazyl) (IC50) while total phenolic, total flavonoids, and vitamin C were determinated by UV-Vis spectrophotometry. Honey samples used were commercial packaging rambutan honey (MR), commercial packaging rubber honey (MK), and commercial unpackaging rambutan honey (MR2). The combination ratio of honey and namnam leaves extract was 1:1, 1:2 and 2:1 (b/b). The highest value of total phenolic, total flavonoids, vitamin C and antioxidant activity in namnam leaves extract (N) was 267.690 mg GAE/g, 12.284 mg QE/g, 203.500 mg AA/g and IC50 0.004 mg/mL, respectively. The highest value of total phenolic was 0.588 mg GAE/g in MR2, while the highest value of total flavonoids and antioxidant activity (IC50) were 0.027 mg QE/g and 21.576 mg/mL in in MR, respectively. Combination MR and MR2 with namnam leaves extract (MR-N and MR2-N) with ratio 1:2 gave the highest antioxidant activity with IC50 value 0.005±0.000 mg/mL in both samples. The highest value of total phenolic, total flavonoid, and vitamin C in MR-N and MR2-N was 266.027 mg GAE/g, 9.790 mg QE/g, and 100.33 mg AA/g, respectively. Therefore, the combination is potential as a functional food Madu dan daun namnam (Cynometra cauliflora) telah terbukti memiliki aktivitas antioksidan. Kombinasi kedua bahan ini akan sangat potensial digunakan sebagai pangan fungsional. Pada penelitian ini, antioksidan diukur dengan metode DPPH (1,1-difenil-2-pikrilhidrazil) (IC50), sedangkan total fenolik, total flavonoid, vitamin C menggunakan spektrofotometer UV-Vis. Sampel madu yang digunakan adalah madu rambutan kemasan komersial (MR), madu karet kemasan komersial (MK), dan madu rambutan tanpa kemasan komersial (MR2). Perbandingan kombinasi madu dan ekstrak daun namnam masing-masing 1:1, 1:2 dan 2:1 (b/b). Hasil analisis menunjukkan bahwa total fenolik, total flavonoid, vitamin C dan aktivitas antioksidan tertinggi terdapat pada ekstrak daun namnam (N) masing-masing sebesar 267,690 mg GAE/g, 12,284 mg QE/g, 203,500 mg AA/g dan IC50 0,004 mg/mL. Kandungan total fenolik tertinggi pada sampel madu adalah MR2 sebesar 0,588 mg GAE/g, sedangkan total flavonoid dan aktivitas antioksidan tertinggi pada MR yaitu 0,027 mg QE/g dan IC50 21,576 mg/mL. Sampel MR dan MR2 kombinasi dengan ekstrak daun namnam (MR-N dan MR2-N) dengan perbandingan 1:2 memberikan aktivitas antioksidan tertinggi dengan nilai IC50 sebesar 0,005 ± 0,000 mg/mL. Total fenolik, total flavonoid, dan vitamin C tertinggi  pada kombinasi MR-N dan MR2-N masing-masing sebesar 266,027 mg GAE/g, 9,790 mg QE/g, dan 100,33 mg AA/g. Oleh karena itu, kombinasi tersebut potensial sebagai pangan fungsional
Potensi Madu dan Ekstrak Ampas Teh Sebagai Penghambat Tirosinase Untuk Bahan Aktif Kosmetika Pemutih Sumarlin, La Ode; Ernita, Nur; Hajar, Hajar
ALCHEMY:Journal of Chemistry Vol 11, No 2 (2023): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v11i2.19606

Abstract

One way to lighten skin tone is to inhibit the formation of melanin through the inhibition of the tyrosinase enzyme. Bleach acts as an inhibitor of melanin production and is known as a competitive tyrosinase inhibitor. In this study, the potential for teabag and honey dregs will be analyzed singly and in the form of a mixture. The method used is an anti-tyrosinase test using L-DOPA as a substrate. The results of the analysis showed that the tea extract samples were almost all positive test compounds (Flavonoids, Alkaloids, Tannins, Saponins, Steroids) except for Quinones and Triterpenoids. Honey for the positive sample was only for saponin compounds, while those for other compounds were negative. Tea extract has the potential to inhibit the tyrosinase enzyme, because it contains flavonoid compounds, tannins and steroids. Tests for inhibition of the tyrosinase enzyme in honey and tea and a mixture of the two have IC50 values 1000 g/ml, so the inhibitory activity is very weak. However, research has shown that tea bag dregs and honey have the potential to be used as active ingredients in whitening cosmetics.
Co-Authors . Faturrahman . Masitoh . Suryatna A.S. Satyaningtijas Achmad Tjachja Achmad Tjachja Nugraha Achmad Tjahja Ade Candra Agik Suprayogi Ahmad Fathoni Ahmad Fathoni Ahmad Saepul Mujab Ahmad Tjahja Nugraha, Ahmad Tjahja Alfida Zakiyah, Alfida Alfionita Octa Nur Zidni Andhi Vitaria Andriantoro Andriantoro Anna Muawanah Arif Sumantri Arif Sumantri Bagus Sediadi Bandol Utomo Barokah Aliyanta Dany Poltak Marisi Dede Sukandar Dikdik Mulyadi Dina Fransiska Eka Rizki Amelia Eka Rizki Amelia Ericka Putri Wijaya Farhan Riza Afandi Farida Ariyanti Fuady Hanief Hajar Hajar Hajar Hajar Hendrawati Hendrawati Hilyatuz Zahroh Hilyatuz Zahroh Ihya Sulthonuddin Iin Ana Rizqi Ika Amalia, Ika Jane Ratini Putri Lela Mukmilah Yuningsih Lia Pratiwi M. Iqbal Suryatama Manadzhir Mahalli Marisi, Dany Poltak Megga Ratnasari Pikoli Melina Hadera Meyliana Wulandari Nadya Uswatun Hasanah Nani Radiastuti Nida Sopiah Nur Enita Nur Ernita Nur Ernita Nur Ernita Nurhasni, N. Nurul Amilia Nurul Amilia Prima Soheti Prita Wardhani Rahminiwati, Min Ratna Istianah Riana Octavia Rita Mukhtar S Hermanto Salih Muharam Sandra Hermanto Siti Nurbaya Siti Nurbayti Soheti, Prima Sri Yadial Chalid Sri Yadial Chalid Suharyono Suharyono Syed Azhar Syed Sulaiman, Syed Azhar Syed Syifa Fauziah Teguh Wahyono Tri Retno Dyah Larasati Widya Fatimah Yoga Asmara Yunesfi Syofyan Zakki R Mubarok