Ali Taqwim
Faculty of Dentistry University of Jendral Soedirman Purwokerto 53146

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Effects of Monosodium Glutamate (MSG) intake during pregnancy and lactation on calcium levels in the teeth and alveolar bones of rat offspring Taqwim, Ali; Noor, Anggita Rizky Rizali; Wati, Erna Kusuma; Ramadhani, Amilia
Majalah Kedokteran Gigi Indonesia Vol 10, No 1 (2024): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.82261

Abstract

Monosodium glutamate (MSG) is a widely used food additive that enhances flavor. However, excessive MSG intake during pregnancy and lactation may pose health risks to both the mother and the developing fetus, particularly in terms of tooth and bone development. This study aimed to investigate the effect of maternal oral administration of MSG during pregnancy and lactation on calcium levels in the teeth and alveolar bones of rat offspring. This research is a laboratory experiment with a post-test-only control group design. Thirty pregnant Sprague Dawley rats were randomly allocated into three groups: a control group receiving distilled water and two treatment groups receiving MSG at doses of 3 mg/g BW and 6 mg/g BW, respectively. MSG was administered orally from the 5th day of pregnancy until the end of the lactation period. The calcium levels in the teeth and alveolar bones of the offspring were measured using atomic absorption spectrophotometry (AAS). Data were analyzed using one-way ANOVA and post hoc LSD. The mean calcium levels in the teeth and alveolar bones of the offspring in the MSG treatment groups were significantly lower than those in the control group (p < 0.05). The reduction in calcium levels was dose-dependent, with the higher MSG dose (6 mg/g BW) resulting in a more pronounced decrease compared to the lower dose (3 mg/g BW). Maternal MSG intake during pregnancy and lactation leads to a dose-dependent decrease in calcium levels in rat offspring’s teeth and alveolar bones, suggesting that excessive MSG intake during these critical periods potentially leads to impaired tooth and bone development.
Caries and Oral Health related Quality of Life Amongs Thalassemia Major Children Oktadewi, Fitri Diah; Purnama, Ryana Budi; Taqwim, Ali; financia, dwi cinthya; cahyaningrum, nadya elsa
Kesmas Indonesia Vol 16 No 2 (2024): Jurnal Kesmas Indonesia
Publisher : Jurusan Kesehatan Masyarakat dan Fakultas Ilmu-Ilmu Kesehatan Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.ki.2024.16.2.10156

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Patients with thalassemia generally have high caries rates. Dental caries in children can have a negative impact on daily activities and quality of life. Researchs on the comparison of caries and oral health related quality of life between thalassemia children and healthy children provides inconsistent results. The aim of this study was to compare dental caries and oral health-related quality of life between children with thalassemia major and healthy children. This study was a cross sectional study involving 17 children with thalassemia mayor and 22 healthy children who were selected by purposive sampling in Banyumas, Central Java. Caries was assessed using the DMFT/deft index through digital panoramic radiographs and clinical photographs of the oral cavity. Oral health-related quality of life was assessed using the Indonesian version of the Child Oral Health Impact Profile-SF 19 questionnaire. DMFT /deft scores in thalassemia major children and healthy children were 2.64 ± 2.06 and 2.23 ± 1.38, respectively. OHRQoL scores in thalassemia major and healthy children were 56.82 ± 10.35 and 56.73 ± 7.70, respectively. There was no significant difference between DMFT/deft scores and oral health-related quality of life scores between thalassemia major children and healthy children (p=0.663 and p=0.974, respectively). Nevertheless, oral health in children with thalassemia should be improved.
Management of Acute Primary Herpetic Gingivo-stomatitis in Children Marzuqi, Naila; Taqwim, Ali; Vitasari, Niken Rahma; Saskianti, Tania
Indonesian Journal of Dental Medicine Vol. 2 No. 2 (2019): Indonesian Journal of Dental Medicine
Publisher : Faculty of Dental Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijdm.v2i2.2019.29-31

Abstract

Background: Acute primary herpetic gingivostomatitis is the symptomatic presentation of the initial exposure to the herpes simplex virus 1 (HSV-1). The clinical condition of acute primary herpetic gingivostomatitis is characterized by a prodromal of fever followed by an eruption of painful, ulcerative lesions of the gingiva and mucosa, and often, perioral, vesicular lesions. Purpose: The case reported management of acute primary herpetic gingiva-stomatitis in a 6 years old boy. Case: A 6-year-old boy with complaints of difficulty eating or drinking due to pain associated with multiple ulcers in the oral cavity and lips. Patient have been living in boarding school since 6 months ago and was complained of stomatitis which have occurred 4 days ago followed by fever and malaise. Case Management: The patient was instructed to eat nutritious (high calorie and protein diet), soft, blend diet and the following medications were prescribed: (1) antiviral drug (Acyclovir® tablet 200mg) for four times a day; (2) topical hyaluronic acid gel (Aloclair® gel 8ml) to be applied on lesions; (3) mouthwash containing benzydamine hydrochloride (Tantum Verde® 15ml) for three times a day; and (4) multivitamin syrup for three times a day. Conclusion: The case reported that the drugs treatment was used according to the severity of HSV-1 infection and patient's symptoms of acute primary herpetic gingiva-stomatitis. Providing supportive care and educating about transmission of the virus are important aspects of nursing care.
THE ANALYSIS OF INTERINCISAL AND VERTICAL ANGLES ON CONVEX FACIAL PROFILE ACCORDING TO STEINER (STUDY OF JAVANESE ORTHODONTIC PATIENTS IN BANYUMAS REGENCY) Aisyah Dewi Kusuma, Nur; Handayani, Fani Tuti; Budi Purnama, Ryana; Taqwim, Ali; Rachel Keshena, Jatu
Journal of Vocational Health Studies Vol. 7 No. 2 (2023): November 2023 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V7.I2.2023.95-99

Abstract

Background: Orthodontic treatment focuses on correcting abnormal teeth and jaw positions for better facial esthetics. Abnormal teeth can be corrected by interincisal angle, while vertical angle can determine the facial growth pattern. Purpose: Analyze the interincisal and vertical angles on convex facial profiles of Javanese orthodontic patients in the Banyumas Regency. Method: Analytical descriptive research was conducted with a cross-sectional design. A purposive sampling technique was used to obtain lateral cephalograms totaling 33 based on inclusion and exclusion criteria from three locations. The lateral cephalogram was traced using tracing paper, while the interincisal and vertical angles were measured based on Steiner's analysis. Two operators carried out measurements, starting with tracing validation and the Kappa test. Furthermore, the results were from the average measurement of the two operators. Result: The mean interincisal and vertical angles were 115.30° and 37.04° with a protrusive inclination and hyperdivergent face, respectively. The correlation test showed a p-value of 0.432 (p > 0.05), meaning there was no relationship between the interincisal and vertical angles in Javanese orthodontic patients. Conclusion: There is no relationship between the interincisal and vertical angles in the convex facial profile of Javanese orthodontic patients in the Banyumas Regency.
Peningkatan Kemampuan Pemeliharaan Kesehatan Gigi Dan Mulut Pada Siswa/i Tunarungu Di SLB B Yakut Purwokerto Oktadewi, Fitri Diah; taqwim, ali; satrio, rinawati; dias andrianto, angger waspodo
Linggamas: Jurnal Pengabdian Masyarakat Vol 2 No 2 (2025): Linggamas: Jurnal Pengabdian Masyarakat
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.linggamas.2025.2.2.13673

Abstract

Siswa tunarungu memiliki keterbatasan fisik dalam mendengar dan umumnya diikuti oleh gangguan bicara.. Keterbatasan ini menjadi hambatan bagi penyandang tunarungu untuk memperoleh pengetahuan tentang kesehatan gigi dan mulut yang nantinya akan menentukan sikap dan tindakan anak dalam menjaga kebersihan rongga mulutnya . SLB B Yakut Purwokerto merupakan sekolah untuk siswa tunarungu wicara yang terletak di daerah Kranji, Banyumas, Jawa Tengah. Kegiatan ini bertujuan dalam untuk meningkatkan kemampuan pemeliharaan kesehatan gigi dan mulut pada siswa tunarungu di SLB B Yakut Purwokerto. Khalayak sasaran dalam kegiatan ini adalah siswa tunarungu SLB B Yakut Purwokerto berjumlah 74 siswa dari usia TK hingga SMA. Metode kegiatan ini berupa pemberian edukasi melalui demonstrasi sikat gigi dengan phantom gigi didampingi guru dan pemeriksaan gigi dan mulut. Pemeriksaan rongga mulut menunjukkan angka karies yang cukup tinggi. Hasil pemeriksaan rongga mulut akan diserahkan kepada pihak sekolah dan orang tua agar dapat ditindaklanjuti.
EFEKTIVITAS MIKROEMULSI-GEL SELEDRI (Apium graveolens) DALAM MENURUNKAN KADAR CALPROTECTIN GCF PADA MODEL PERIODONTITIS KRONIS Prihastuti, Christiana Cahyani; Salisa, Ziyada; Rakhmawati, Rakhmawati; Taqwim, Ali; Satrio, Rinawati
B-Dent: Jurnal Kedokteran Gigi Universitas Baiturrahmah Vol 12, No 1 (2025): Vol 12 No 1 (Juni 2025)
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/jbd.v12i1.1812

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Background: Calprotectin is a neutrophil secretion product that serves as one of the biomarkers for periodontal tissue inflammation. Calprotectin levels in Gingival Crevicular Fluid (GCF) are reported to increase in periodontitis conditions. Celery (Apium graveolens) contains flavonoids and polyphenols that have potential anti-inflammatory properties. The topical microemulsion-gel formulation offers optimal bioavailability of active substances when applied to periodontal pockets. Objective: To determine the effect of celery microemulsion-gel on GCF calprotectin levels in an experimental model of chronic periodontitis. Methods: This experimental study used 25 male Wistar rats (Rattus norvegicus) divided into 5 groups (n=5): healthy control group, negative control group, and three treatment groups receiving Apium graveolens microemulsion-gel at concentrations of 25%, 50%, and 100%. The chronic periodontitis model was induced using P. gingivalis. Apium graveolens microemulsion-gel (0.7 ml) was applied to the inflamed gingival sulcus for 7 days. GCF samples were collected using filter paper and calprotectin levels were measured using ELISA method. Data analysis was performed using One-Way ANOVA followed by Least Significant Difference (LSD) test. Results: GCF calprotectin levels in the Apium graveolens microemulsion-gel treatment groups were lower compared to the negative control group (p<0.05), with the lowest levels observed in the 50% concentration group. There was no significant difference between the treatment groups and the healthy control group (p>0.05). Conclusion: Apium graveolens microemulsion-gel effectively reduces GCF calprotectin levels in chronic periodontitis model, indicating an anti-inflammatory effect.
IRON OVERLOAD, COMPROMISED SALIVARY FUNCTION, AND DENTAL CARIES RISK IN BETA-THALASSEMIA MAJOR: A CROSS-SECTIONAL Ramadhani, Amilia; Pramuditya, Hafizh Zufar; Nurcahyani, Putri Silvia; Taqwim, Ali; Basalamah, Muhammad; Widodo, A. Haris Budi; Rujito, Lantip
Indonesian Journal of Dentistry Vol 5, No 2 (2025): August 2025
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/ijd.v5i2.17807

Abstract

Background: β-thalassemia major patients exhibit higher dental caries prevalence due to systemic complications including iron overload from regular blood transfusions. This study aimed to assess dental caries status, salivary pH, and buffer capacity in β-thalassemia major patients and investigate correlations with ferritin blood concentration.Method: A cross-sectional analytical study was conducted on 24 β-thalassemia major patients aged 12-17 years. Salivary function was assessed by salivary pH and buffer capacity. Dental caries status was evaluated using the DMF-T index. Ferritin blood concentrations were correlated with salivary function and dental caries using Pearson analysis.Outcome: Mean salivary pH was 5.74±0.63 (acidic), buffer capacity was 3.98±0.21, DMF-T score was 6.17±1.97, and ferritin level was 5830.54±2823.91 ng/mL. Ferritin levels showed moderate negative correlations with salivary pH (r=-0.718, p<0.001) and buffer capacity (r=-0.737, p<0.001), and positive correlation with DMF-T scores (r=0.696, p<0.001). Strong negative correlations were found between DMF-T scores and salivary pH (r=-0.915, p<0.001) and buffer capacity (r=-0.913, p<0.001).Conclusion: Iron overload significantly compromises salivary parameters, creating an acidogenic oral environment that promotes dental caries development in β-thalassemia major patients, emphasizing the need for integrated oral health monitoring in thalassemia management protocols.
Pemanfaatan dan Potensi Bahan Alam di Banyumas sebagai Agen Anti Karies: Telaah Pustaka Nuryana, Putri Ayu; Taqwim, Ali; Zakiya, Aida; Aliyyu, Wienda Cinta; Purwanto, Rizky Ganda
Journal of Dental and Biosciences Vol 1 No 2 (2024): Journal of Dental and Biosciences
Publisher : Jurusan Kedokteran Gigi Fakultas Kedoketaran Universitas Jenderal Soedirman

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Abstract

Latar belakang: Pengobatan dengan memanfaatkan tumbuhan sudah menjadi budaya dan tradisi. Wilayah Banyumas memiliki keanekaragaman hayati baik dari empon-empon, tanaman, buah, ataupun hewan yang dapat dimanfaatkan potensinya untuk mencegah dan menghentikan karies gigi. Tujuan: mengkaji pemanfaatan dan potensi bahan alam yang melimpah di Kabupaten Banyumas sebagai agen anti karies. Tinjauan Pustaka: Bahan alam yang melimpah di Banyumas seperti kayu manis, kecombrang, bawang merah, daun kemangi, daun sirih, cengkeh, serai wangi, buah naga, jeruk nipis, kakao, cangkang telur ayam, dan cangkang keong sawah memiliki senyawa aktif metabolit sekunder berupa flavonoid, tannin, saponin, alkaloid, asam p-hydroxybenzoate, fenol, phenol hydroquinone, minyak atsiri, theobromine,dan kalsium karbonat yang memiliki kemampuan sebagai agen anti karies. Kesimpulan: Bahan alam kayu manis, kecombrang, bawang merah, daun kemangi, daun sirih, cengkeh, serai wangi, buah naga, jeruk nipis, kakao, cangkang telur ayam dan cangkang keong sawah yang terdapat di Banyumas berpotensi dan bermanfaat sebagai agen anti karies.
Potensi Bahan Alam di Banyumas Sebagai Agen Untuk Mempercepat Penyembuhan Luka Jaringan Lunak Rongga Mulut Rambiati, Wahyu Intan Putri; Sunaryono, Rizqi Amalia; Husna, Neneng Syifa Sofiyatul; Yuliani, Ananda Putri; Taqwim, Ali
Journal of Dental and Biosciences Vol 2 No 02 (2025): Journal of Dental and Biosciences
Publisher : Jurusan Kedokteran Gigi Fakultas Kedoketaran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jdentbios.2025.2.02.11101

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Background: Wounds in the oral cavity are something that cannot be avoided in dental practice, especially in several procedures such as incisions, excisions and gingivectomy. The wound healing process takes a long time, increasing the risk of infection, which will hinder the healing process. The main focus in treating wounds is fast healing with optimal results. Currently, it is necessary to develop alternatives for the use of natural ingredients that can speed up the wound healing process with minimal side effects. Objective: The purpose of writing this article is to explore the potential of natural ingredients in Banyumas which have the effect of accelerating the healing of soft tissue wounds in the oral cavity. Method: This literature review source search method refers to reference sources in the form of PubMed and Google Scholar and then data analysis is carried out according to the specified topic. Result: Natural ingredients that are widely produced in Banyumas include cinnamon leaves (Cinnamomum verum), red ginger rhizomes (Zingiber officinale Var Rubrum rhizoma), turmeric (Curcuma longa Linn.), bay leaves (Syzygium polyanthum), aloe vera (Aloe vera L.) , robusta coffee (Coffea canephora), papaya leaves (Carica papaya L.), red dragon fruit (Hylocereus polyrhizus), and land snail mucus (Achantina fulica) contain active ingredients that can accelerate the healing of soft tissue wounds in the oral cavity. Conclusion: There are natural ingredients in Banyumas that contain active ingredients that can accelerate the healing of soft tissue wounds in the oral cavity.
Pengetahuan Orangtua tentang Penularan COVID-19 dan Kepatuhan Perawatan Berulang Gigi Anak di RSGM Unsoed Selama Pandemi COVID-19 Sarah, Putri; Lestari, Rr. Diyah Woro Dwi; Taqwim, Ali; Oktadewi, Fitri Diah; Anggono, Fajar Dwi
Journal of Dental and Biosciences Vol 1 No 2 (2024): Journal of Dental and Biosciences
Publisher : Jurusan Kedokteran Gigi Fakultas Kedoketaran Universitas Jenderal Soedirman

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Abstract

Latar Belakang: Masalah kesehatan gigi rentan terjadi pada anak usia sekolah dan pengetahuan orang tua mengenai penularan COVID-19 diduga berperan dalam kepatuhan melakukan perawatan gigi berulang di masa pandemi. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan orang tua tentang penularan COVID-19 dengan kepatuhan anak melakukan perawatan gigi berulang. Metode: Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross-sectional. Metode pengambilan sampel adalah total sampling dengan kriteria inklusi dan eksklusi. Subjek terdiri dari 50 orang tua pasien anak usia 6-12 tahun yang pernah melakukan perawatan gigi berulang di RSGM Unsoed. Instrumen penelitian berupa angket online untuk mengukur pengetahuan. Analisis data dilakukan dengan menggunakan analisis univariat dan bivariat dengan uji chi-square. Hasil: Terdapat hubungan yang signifikan antara pengetahuan orang tua tentang penularan COVID-19 dengan kepatuhan anak melakukan perawatan gigi berulang (p=0,006). Nilai koefisien kontingensi sebesar 0,41 menunjukkan kekuatan hubungan yang moderat antara kedua variabel. Kesimpulan: Pengetahuan orang tua tentang penularan COVID-19 berhubungan dengan kepatuhan melakukan perawatan gigi berulang pada anak di RSGM Unsoed. Selain itu, memberikan informasi dan edukasi kepada orang tua tentang tindakan pencegahan COVID-19 di bidang kedokteran gigi penting untuk meningkatkan kepatuhan pengobatan.