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All Journal Jurnal Riset Kimia Jurnal Penelitian Pendidikan IPA (JPPIPA) JURNAL EKSAKTA PENDIDIKAN (JEP) JURNAL PHOTON Acta Biochimica Indonesiana Sainstek : Jurnal Sains dan Teknologi Journal of Chemistry Education and Integration Jurnal Penelitian dan Pendidikan Agama Islam
Lisa Utami
Program Studi Pendidikan Kimia, Fakultas Tarbiyah dan Keguruan, Universitas Islam Negeri Sultan Syarif Kasim, Riau, Indonesia
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Materials Science & Nanotechnology Mathematics Nursing Physics Social Sciences Other

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PENGARUH MODEL TTW (THINK TALK AND WRITE) TERHADAP HASIL BELAJAR KIMIA SISWA PADA MATERI PEMANASAN GLOBAL Novriza, Novriza; Utami, Lisa
Journal of Chemistry Education and Integration Vol 3, No 1 (2024): Journal Of Chemistry Education and Integration
Publisher : Universitas Islam Negeri Sultan Syarif Kasim Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24014/jcei.v3i1.29006

Abstract

AbstractThe low of student learning achievement was one of obstacles in the learning process.  This research aimed at finding out the effect of Think Talk and Write learning model toward student learning achievement on Global Warming lesson at the tenth grade of State Senior High School 3 Pekanbaru.  Experiment method was used in this research.  It was quasi-experiment with pretest and posttest non-equivalent control group design.  All the tenth-grade students (8 classes) were the population of this research, and the samples were the tenth-grade students of class KM6 as the control group and students of class KM3 as the experiment group.  Random sampling technique was used in this research.  Multiple choice test was the technique of collecting data, and processing the data was done by using t-test and determination coefficient.  In t-test, the result of sig. (2-tailed) 0.000 was lower than 0.05, so H0 was rejected and Ha was accepted.  In determination test, the score of r2 was 0.030, so it could be concluded that Think Talk and Write learning model affected student learning achievement on global warming lesson 3%. Keywords : Effect, Think Talk and Write, Learning Achievement, Global Warming
Studi Molecular Docking dan Evaluasi Farmakokinetik Senyawa Analog Pirazol Turunan Benzen-Sulfonilurea sebagai Inhibitor Enzim Aldose Reduktase and α-Glukosidase Menggunakan Pendekatan In Silico Fatisa, Yuni; Utami, Lisa; Syahri, Jufrizal; Jasril, Jasril; Lazulva, Lazulva
Jurnal Riset Kimia Vol. 15 No. 2 (2024): September
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v15i2.633

Abstract

The pyrazole scaffold modification in various chemical structures on several studies has shown various biopharmacological activities. This study aims to predict the potential inhibition of pyrazole analogs derived benzene-sulfonylurea (4A, 4B, 4E, 5A, 5C, 5D) against the α-glucosidase (3A4A) and aldose reductase (3RX2) enzymes based on a molecular docking approach using Molecular Operating Environment (MOE) 2020.0102 software and evaluate pharmacokinetic profile (ADMET). In this study, the six test compounds were obtained from previous studies that have been proven antihyperglycemic. The results showed that all the 3,5-disubstituted benzene-sulfonylurea derivative pyrazole analogs are predicted to have low inhibitory activity against the α-glucosidase enzyme. Further, all compounds showed good aldose reductase inhibitor activity and had lower binding free energy values ​​than tolrestat as the positive control (-6.82 kcal/mol). Compound 5C has the best potential inhibitory activity against the aldose reductase enzyme compared to the other test compounds, because it has the lowest binding free energy value (-8.76 kcal/mol) and interacts with important residues on the receptor forming four hydrogen bonds, namely the carbonyl group of SO2 with residues Trp111 and His110, and the carbonyl group of the amide with residues His110 and Tyr48, as well as 3 hydrophobic bonds, namely a pyrazole ring with residues Leu300, Trp219 and a furan ring with Phe122. ADMET properties of the compounds are also predicted. This information provides an opportunity for a 5C compound as an aldose reductase inhibitor agent to develop drug candidates with better and safer activities.
Effectiveness of the Flipped Classroom Model on the Problem-Solving Abilities of Science Education Students: A Meta-analysis Study Santosa, Tomi Apra; Ilahi, Dian Purnama; Utami, Lisa; Festiyed, Festiyed; Desnita, Desnita; Asrizal, Asrizal; Diliarosta, Skunda; Yerimadesi, Yerimadesi; Arsih, Fitri
Jurnal Penelitian Pendidikan IPA Vol 9 No SpecialIssue (2023): UNRAM journals and research based on science education, science applic
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9iSpecialIssue.6318

Abstract

A concise the purpose of the study was to determine the effectiveness of the flipped classroom model on the problem solving skills of science education students. A total of 950 studies were analyzed obtained from six databases consisting of ScienceDirect, Education Resources Information Center (ERIC), Wiley Journal, Springer; ProQuest and IEEE aim to get relevant articles published in 2020-2023.  From the analyzed studies, 21 studies were selected for meta-analysis.  Data analysis with JSAP software.  The results showed that the flipped classroom model provides high effectiveness on the problem solving skills of science education students (rRE = 0.97; 95 % CI [0.840; 1.111]; p < 0.001). This finding provides information for teachers to apply the flipped classroom model to improve students' problem solving skills in learning
Evaluating the Impact of Problem Based Learning on Student's Metacognition in Science Learning: A Meta-Analysis Review Ilahi, Dian Purnama; Festiyed; Yerimadesi; Yulkifli; Utami, Lisa; Ratih, Arista
Jurnal Penelitian Pendidikan IPA Vol 10 No 8 (2024): August
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i8.7892

Abstract

This study aims to evaluate the impact of problem-based learning models on students' metacognition in science learning. This type of research is a meta-analysis using the PRISMA 2020 method. Articles from Scopus and Google Scholar databases were collected using Publish or Perish (PoP) software. From 8 articles that met the inclusion criteria, a total of 20 data were obtained to be processed in the meta-analysis. Data analysis was used with JASP software.The results of this metaanalysis research show that problem-based learning model provides moderate effectiveness on students' metacognition in science learning (r RE = 0.67; SE = 0.16; z = 4.24; p < 0.001). This shows that problem-based learning model can improve students' metacognition in science learning. Through PBL, students become more aware of their cognitive strategies and learn to organise them more effectively. Incorporating PBL into the science curriculum can significantly improve students' metacognition, leading to more independent and effective students. Therefore, widely adopting PBL in science education is recommended to achieve better learning outcomes
Co-Authors . Ria Wulandari Asrizal Belviyani, Jenny Desnita Fajriati, Putri Festiyed Festiyed Fitri Arsih Fitri, Amelia Ramadhani Ilahi, Dian Purnama Jasril Jasril Jufrizal Syahri Lazulva Lazulva, Lazulva Nasution, Herry Syahbannuddin Novesar Jamarun Novriza, Novriza Parinduri, Sari Atika Ratih, Arista refelita, fitri Santosa, Tomi Apra Siagian, Nova Lestari Skunda Diliarosta Suriani, Teti Syukri Arief yenti, elvi Yerimadesi Yerimadesi Yerimadesi Yulkifli Yuni Fatisa Yusbarina Yusbarina, Yusbarina Zona Octarya