Article Per Year (5 Year)
p-Index From 2021 - 2026
6.339
P-Index
This Author published in this journals
All Journal MNJ (Malang Neurology Journal) The Indonesian Biomedical Journal Universa Medicina Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education IJRETINA - International Journal of Retina Ophthalmologica Indonesiana
Syntia Nusanti
Ophthalmology Department, Faculty Of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Published : 45 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 45 Documents
Search

 1   2   3   4   5 
Outcome and Safety of Different Cumulative Doses and Protocols of Intravenous Methylprednisolone in Moderate to Severe and Active Graves’ Ophthalmopathy Amelya Permata Sari; M Sidik; Syntia Nusanti
Majalah Oftalmologi Indonesia Vol 43 No 1 (2017): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v43i1.131

Abstract

Background: Graves’ ophthalmopathy (GO), also known as Graves’ orbitopathy or thyroid eye disease, has a potential sight-threatening complications. The activity and severity are important determinants in GO and are implications for treatment. Intravenous Glucocorticoid (GC) was associated with significantly greater efficacy and was better tolerated than oral route in the treatment of patients with moderate to severe and active GO. Intravenous GC has a variation cumulative dose and protocols; meanwhile the optimal treatment is still undefined. The aim of this literature review was to analyze the outcome and safety of different cumulative doses and protocols of intravenous methylprednisolone of patients with moderate to severe and active GO. Methods: The literature search was conducted from Google Scholar and Pubmed for journal articles that were published and related to the use of IVGC in moderate to severe and active GO Results: From the keywords mentioned, titles were screened for eligibility and seventeen articles were found. After being checked for the duplication, the articles were screened based on the abstracts and/or full texts. As many as eight articles met the inclusion criteria, others were excluded. Conclusion: Intravenous GC therapy in moderate to severe and active GO provide effect in reducing CAS, decreasing lid aperture size, decreasing proptosis size, and disappearing diplopia. A protocol uses a low cumulative doses (<5 g) of methylprednisolone weekly for 6 weeks and then halved dose weekly for another 6 weeks are preferred due to higher response in clinical outcome and safety profile.
Gambaran Parameter Optical Coherence Tomoghraphy Papil dan Hubungannya dengan Fungsi Penglihatan pada Pasien Non-Arthreritic Anterior Ischemic Optic Neuropathy di FKUI-RSCM Kirana Valenchia Valenchia; M Sidik; Syntia Nusanti
Majalah Oftalmologi Indonesia Vol 44 No 1 (2018): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v44i1.156

Abstract

Tujuan : Untuk menggambarkan parameter diskus optik dan retinal nerve fiber layer (RNFL) pada pasien non arteritic anterior ischemic optic neuropathy (NAION) dan untuk menggambarkan korelasinya dengan defek lapang pandang dan tajam penglihatan. Metode: 27 pasien NAION disertakan pada penelitian ini. Pemeriksaan berikut dilakukan secara potong lintang: Humphrey HFA II-i 750 24-2 threshold , tajam penglihatan dengan koreksi (TPDK) dengan Snellen chart dan optical coherence tomography (OCT) StratusTM fast optic disc dan fast RNFL 3.4mm. Hasil : Kami menemukan 14 mata (25,9%) dengan diskus optik edema, 21 mata (38,9%) dengan diskus optik atrofi dan 19 mata dengan diskus optik normal. Disk Area dan Rim cross sectional area dapat membedakan kondisi diskus edema, atrofi, dan normal (DA: 3,52 ± 1,16; 2,73 ± 0,55; 2,59 ± 0,44; p = 0,01) (RCSA : 2,44 ± 1,34; 1,52 (0,94-3,02); 1,83 ± 0,34; p = 0,014) masing-masing. Ketebalan RNFL di semua kuadran juga dapat membedakan morfologi diskus. Tidak ada korelasi yang ditemukan antara parameter diskus optik-RNFL dengan defek lapang pandang (LP). Kami menemukan korelasi sedang antara ketebalan RNFL kuadran temporal dengan TPDK (r -0,433; p = 0,05). Kesimpulan : Parameter diskus optik dan RNFL dengan OCT dapat digunakan untuk membedakan morfologi diskus optik. Ketebalan kuadran temporal RNFL adalah prediktor baik tajam penglihatan sentral pada pasien dengan NAION karena fungsi makula.
Karakteristik, Hasil Terapi dan Prediktor Keberhasilan Terapi Pasien Neuropatik Optik Traumatik (NOT) Divisi Neurooftalmolog Rumah Sakit Cipto Mangunkusumo Hisar Daniel; Syntia Nusanti; M Sidik
Majalah Oftalmologi Indonesia Vol 44 No 1 (2018): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v44i1.157

Abstract

Latar belakang : Mengetahui karakteristik demografis pasien, hasil terapi yang diberikan dan menemukan faktor prediktor keberhasilan terapi pasien NOT di RSCM. Metode : Penelitian deskriptif menggunakan data sekunder dari telusur rekam medis pasien yang terdiagnosis NOT dari poliklinik Divisi Neuro-Oftalmologi (NO) Departemen Medik Mata FKUI/RSCM pada periode Januari 2014 hingga Desember 2015. Hasil : Karakteristik demografik pasien NOT di RSCM ialah 82,4% laki-laki, dan rerata usia adalah 22,47 ± 10,68 tahun. Sebanyak 50% datang dalam rentang kurang dari 24 jam pasca trauma. Penurunan tajam penglihatan berat (58,8% NLP), 67,6% dengan RAPD positif, dan papil nervus optik yang bervariatif. Sebanyak 67,6% ditatalaksana dengan metilprednisolon intravena (1 g/hari selama 3 hari), 26,5% dengan metilprednisolon oral (0,8mg/kgBB/hari). Perbaikan tajam penglihatan dijumpai pada 32,4% pasien yang mendapatkan pengobatan selama satu bulan. Pasien close globe injury yang mendapat terapi < 24 jam secara statistik terjadi perbaikan tajam penglihatan (p = < 0.05). Kesimpulan : Faktor prediktor seperti awitan trauma, awitan terapi inisial dan hasil pencitraan pada penelitian ini belum kuat untuk menjadi acuan dalam memprediksi keberhasilan terapi. Akan tetapi, pasien dengan closed globe injury yang diobati kurang dari 24 jam menunjukkan perbaikan tajam penglihatan yang signifikan. Dosis metilprednisolon IV 1 gram/hari selama 3 hari yang dilanjutkan dengan penirusan dosis per inggu maupun pemberian preparat oral dengan dosis 0.8 mg/KgBB/hari dapat digunakan. Pengobatan dilakukan setidaknya sampai dengan 1 bulan pasca pengobatan karena kurang baiknya kepatuhan pasien neuropati optik traumatic.
Efficacy of High-dose Steroids for Visual Acuity Improvement in Methanol-induced Toxic Optic Neuropathy Theresia Yinski; Syntia Nusanti
Majalah Oftalmologi Indonesia Vol 44 No 2 (2018): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v44i2.164

Abstract

Introduction : Methanol-induced toxic optic neuropathy (TON) is defined as a visual impairment due to optic nerve damage by methanol poisoning. Not only is this disease entity underdiagnosed at times, this sudden blindness is also often diagnosed at a stage where recovery of vision is no longer possible. Materials and Methods : A literature search was conducted using PubMed, ClinicalKey, Google Scholar and ScienceDirect by combining the keywords ‘methanol’ or ‘methyl alcohol’, ‘intoxication’ or ‘poisoning’, ‘toxic optic neuropathy’, and ‘visual acuity’ with ‘high-dose steroid’. Results : The total amount of subjects in each article varied from 2 to 37, with mean age distribution of 26.34 to 55 years old, where most patients were male. The follow up duration varied from 1 week to 1 year. Four articles do not mention high-dose steroids treatment as therapy while the other four mention use of 1000 mg of intravenous methylprednisolone per day with divided doses of either 2x500 mg or 4x250 mg. Improvement percentages show 100% improvement in all studies that used high-dose steroids, while in the non-high-dose steroids studies the improvement percentages range from 33.33% to 90%. Summary : High-dose steroids are showing efficacy in improving visual acuity and reducing the inflammation in methanol-induced TON. The period of how fast the therapy takes effect is inconclusive, as the mean follow-up time differs widely per study. However, because most of the reviewed studies here are retrospective case series, a larger, more comprehensive study is required to acknowledge more of the efficacy profile.
A Rare Case Report of Bilateral Traumatic Carotid Cavernous Fistula Rafika Sari Fadli; M Sidik; Syntia Nusanti
Majalah Oftalmologi Indonesia Vol 46 No 1 (2020): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v46i1.100019

Abstract

Objective : To increase the awareness for ophthalmologist in diagnosing rare case of bilateral traumatic carotid cavernous fistula that could lead to serious complications. Case description : A 44 years old woman came with chief complaint of squint and diplopia since one month after traffic accident. She had been underwent orbital bone fracture repair at previous hospital immediately. There was complaint of headache, blurred vision, double vision and pain on the eyes one month after trauma. There was no history of redness or proptosis. Examination revealed 6/6 for the right and 6/8.5 for the left eye corrected visual acuity, 30 degrees exotropia, normal intraocular pressures (IOP), restriction on eyes movement especially on the left eye, normal anterior and posterior segment, and no bruit. CT orbital revealed bilateral dilated and tortuous of the ophthalmica vein with suspicious of carotid cavernous fistula (CCF). Patient developed slowly progressive conditions such as proptosis non axial on the left eye, redness with corkscrew appearance on both eyes, restriction of the ocular movement and also founded bruit on both eyes within two months follow up. CT angiography revealed CCF bilateral type A. Patient underwent digital subtraction angiography (DSA) and balloon embolization four months after diagnosed. Conclusion : Although bilateral carotid cavernous fistula is a rare case, performing a suitable diagnostic examination would help to prevent devastating outcome. Prognosis depends on severity and time span from symptoms to treatment.
Sudden Visual Impairment In Sellar Region Tumor: A Case Of Pituitary Apoplexy Anindita Wicitra; Syntia Nusanti; M Sidik
Majalah Oftalmologi Indonesia Vol 46 No 1 (2020): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v46i1.100023

Abstract

Objective : Pituitary apoplexy described as an acute hemorrhagic infarction of the pituitary adenoma causing sudden increase of intra sellar pressure. This condition is a life-threatening disease. The purpose of this article is to report about clinical symptom and methods to diagnose pituitary apoplexy. Methods : A case presentation Result : A 40 y.o male came with a complain of blurry vision since 1 year. Two months before admission, he felt sudden worsening of his visual acuity. He went to private hospital and there was bleeding in his brain CT scan. His right eye visual acuity was 1/300 and his left best visual acuity was 6/12. Relative afferent pupillary defect was positive in the right eye. In funduscopic examination, both of optic nerve head were atrophy. Left eye visual field examination revealed temporal hemianopsia. Cerebral MRI showed a hyper intense lesion on both T1WI and T2WI sequence in sellar region that extends into supra sellar region with sign of sellar floor ballooning. The result of MRI contrast was relatively same and the hormonal exam result was within normal limit. Then he was scheduled for removal tumor surgery from neurosurgery departement. Conclusion : Pituitary apoplexy is a severe clinical syndrome and life-threatening disease. To rule out other disease presenting related symptoms, many ancillary examinations are require to be performed. The treatment of pituitary apoplexy, whether to treat surgically or conservatively, should be made by experts from a multidisciplinary team.
Endovascular Coiling Embolization in Direct Carotid Cavernous Fistula Yulika Harniza; Syntia Nusanti; Jacub Pandelaki
Majalah Oftalmologi Indonesia Vol 46 No 1 (2020): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v46i1.100026

Abstract

Background: Carotid cavernous fistula (CCF) is a rare life-threatening. Rapid endovascular technical development has provided as a safe and effective treatment strategy for direct CCF (DCCF). Coiling treatment is a promising endovascular procedures solution in DCCF. Method: A comprehensive PubMed, Clinical key, and Ophthalmology database search was conducted using appropriate keywords (direct carotid cavernous fistula, endovascular treatment, embolization, and coil). Inclusion criteria was only article in English. Results: Nine studies (8 case series and 1 cohort study) were found suitable. From these results, endovascular coiling treatment can close the fistula with radiological evaluation and improvement in clinical symptoms in most of studies (90% and 88%, respectively). Post-operative and long-term complication were reported in some studies. Conclusion: Efficacy of endovascular coiling embolization appears promising in management of DCCF. There were no intra-operative complications and post-operative complications, such as unraveled micro-coil. The recurrence fistula rate of 4% is common in fistulas with larger tears associated with a larger CCF.
Uncommon Presentation of Wyburn-Mason Syndrome in a Pediatric Patient Julie Barliana; Syntia Nusanti; Manoa Panjaitan; Anggun Yudantha; Laura Djunaedi
Majalah Oftalmologi Indonesia Vol 47 No 1 (2021): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v47i1.100146

Abstract

We report an uncommon presentation of Wyburn-Mason syndrome in a pediatric patient. An 11-year- old girl presenting with no light perception in her right eye. Examination revealed an exotropia and a large and tortuous retina vessel in the posterior part of her right eye. However, other examinations, including dermatological and neurological examination, are within normal limits. Magnetic Resonance Angiography (MRA) showed vascular malformation at the basal cistern that extends to the retrobulbar area. Therefore, a thorough examination of the eye and brain, including MRA, is mandatory in every case, even in pediatric with normal neurological examinations.
A Five-Year Data in Descriptive Study of Systemic and Ocular Risk Factors of Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) and The Correlation to The Clinical Condition Syntia Nusanti; M. Sidik; Andhika Rachman; Miratasya Zulkarnaen
Majalah Oftalmologi Indonesia Vol 47 No 1 (2021): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v47i1.100162

Abstract

Purpose: To acknowledge the demographic, clinical characteristic and the systemic and ocular risk factors in patients with Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) in 2012-2017 in Cipto Mangunkusumo Hospital. Methods: Retrospective descriptive study using the medical record data of 272 patients with NAION in the past 5 years (2012-2017). Results: In the past 5 years, most of the patient’s initial visit visual acuity was <3/60, most patient had 2-3 systemic risk factors, the most frequent risk factors were hypertension (73.9%), obesity(63.5.%), diabetes mellitus (54.6%), smoking habit (54.5%), dyslipidaemia (46%), hypercoagulable state (19%), history of cardiovascular disease (10.3%) and stroke (7.2%). The risk factors were similar in age range ? 50 or bellow. Based on the initial visit time, most of the patient came to CM hospital in average 15.16 (SD±38.3) weeks. Conclusion: This descriptive study showed classic demographic characteristic of NAION cases. Obesity as the second highest probable risk factor is rarely mention in the other studies. Should future detailed studies be done
Evaluasi 97 Pasien Oftalmopati Graves’ Selama 3 Tahun Menggunakan Algoritma Eugogo dan Konsensus Nasional Claudia Hartomuljono; Syntia Nusanti
Majalah Oftalmologi Indonesia Vol 47 No 2 (2021): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v47i2.100305

Abstract

Introduction and Objective: Graves’ ophthalmopathy (GO) is an autoimmune disorder of the orbit that is closely associated with Graves’ diseases. Various classification system was proposed to evaluate clinical findings in GO. As controversy exists in assessment and management of GO there is a need to evaluate and improve diagnostic criteria using practical guideline. Methods: We retrospectively reviewed Graves’ ophthalmopathy patients admitted between 2016 – 2018 to neuro-ophthalmology clinic. Clinical manifestation, the activity, severity and management of the disease were assessed using EUGOGO scale and Clinical Activity Score (CAS). Result: A total of 97 GO patients included in the study. Male to female ratio is 1:2.7 which is highest in the age range of 30-50 years. The majority of patients have hyperthyroid status (41.2%) and bilateral clinical characteristics (77%). A total of 92 patients (94.8%) had visual acuity ?6/18. The most commonly reported clinical sign at the time of assessment is eyelid edema followed by conjunctival injection. Patients with mild EUGOGO status was entirely GO inactive while 5 active GO patients were of moderate-to-severe (4 patients) and 1 patient with sight-threatening GO. Patients with active GO received 1x500 mg of intravenous methylprednisolone for 3 days every week for 4 cycles where at the follow-up there was a significant decrease in CAS score by an average of 3-4 points. Conclusion: The EUGOGO classification system provides diagnostic guidance and appropriate management algorithms for GO patients. Administration of high-dose intravenous methylprednisolone in active GO is still the first choice of therapy.
Co-Authors Agung Nugroho Aleddin, Rommel Amelya Permata Sari Andhika Rachman Andi Marsa Nadhira Anggun Yudantha Anindita Wicitra Annisa Nindiana Pertiwi Anwar Jusuf Anwar Santoso Ardiella Yunard Ari Djatikusumo Aria Kekalih Ayuningtyas, Sita Paramita Bambang Budi Siswanto Brigitta Marcia Bidihardja Brigitta Marcia Budihardja Budiman Bintang Prakoso CECILIA ANGGRAINI Claudia Claudia Hartomuljono Dearaini Dearaini Dearaini Dearaini Desrina Desrina Dewiputri, Salmarezka Dialika Dialika Dicky L Tahapary Dita Permatasari Dita Permatasari Djunaedi Abdul Rachim Elyas Aditya Elyas Aditya Pradana Erika Anggraini Erlina Burhan Fierda Ovita Azhari Gunawan, Calista Nathasya Hisar Daniel Ika Citra Susanti ikhwanuliman Putera Ikhwanuliman Putera Joedo Prihartono Julie Dewi Barliana Laura Agnestasia Djunaedi Lazuardiah Anandi Levina Chandra Khoe Lourisa Ruth Eldenia Lourisa Ruth Eldinia Luminta, Ferdinand Inno M Sidik M Sidik M Sidik M, Sidik M. M. Dio Syaputra M. Sidik M. Sidik M. Sidik Made Paramita Wijayati Manoa Panjaitan Mario Marbungaran Hutapea Marsha Rayfa Pintary Marsha Rayfa Pintary Miratasya Zulkarnaen Mohamad Sidik Mohamad Sidik Mohamad Sidik Muhamad Sidik Muhammad Sidik Muhammad Sidik Nabila Aljufri Nadia Delima Andini Nova Diana Nur Aisyah Rahmawati Oktarina, Virna Dwi Pandelaki, Jacub Paramita Ayuningtyas, Sita Pertiwi, Annisa Nindiana Pintary, Marsha Rayfa Rafika Sari Fadli Rahma Putri, Herdanti Rasyidia Lakmita Putri Rasyidia Laksmita Putri Renindra Ananda Aman Ressa Yuneta Rianti Wulandari Pratiwi Rif'ati, Lutfah Rona Ali Badjrai Salmarezka Dewiputri Salmarezka Dewiputri Sampurna, Kirana Sari, Amelya Permata Seskoati Prayitnaningsih Shidik, Muhammad Sidik, M Sidik, Mohamad Sita Paramita SITA PARAMITA AYUNINGTYAS Theresia Yinski Theresia Yinski Pistari Gondosari Valen Chia Valenchia Valenchia Wienta Diarsvitri Yudantha, Anggun Rama Yulika Harniza Yuri Dwi Mayasari