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Formulasi dan Uji Mutu Fisik Spray gel Ekstrak Etanol Daun Kacang Gude (Cajanus cajan) sebagai Pelembap Kulit Adhasari, Ridha; Ekawati, Ekawati; Salsabila, Attina; Nur Ramadhani, andi Muhammmad; Arifin, Arfiani
Jurnal Novem Medika Farmasi Vol. 4 No. 1 (2025): Volume 4 issue 1 2025
Publisher : Program Studi Farmasi, Universitas Islam Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59638/junomefar.v4i1.1539

Abstract

Kacang gude (Cajanus cajan) merupakan salah satu spesies tanaman famili Leguminoceae yang kaya akan flavonoid yang memiliki manfaat sebagai antioksidan untuk membantu menstabilkan dan menetralisir radikal bebas yang dapat merusak sel-sel dan jaringan sehat. Tujuan penelitian ini untuk memformulasi ekstrak etanol daun kacang gude (Cajanus cajan) dalam sediaan spray gel yang memenuhi syarat uji mutu fisik. Metode yang dilakukan dalam penelitian ini menggunakan metode maserasi dengan pelarut etanol 70% hingga diperoleh ekstrak kental. Selanjutnya dibuat formulasi sediaan spray gel menggunakan variasi konsentrasi daun kacang gude F1 (1%), F2 (1,5%), F3 (2%). Dilakukan pengujian uji mutu fisik meliputi organoleptik, homogenitas, uji pH, viskositas, pola penyemprotan serta waktu kering. Hasil penelitian menunjukkan bahwa daun kacang gude dapat diformulasi dalam bentuk sediaan spray gel dan memenuhi syarat uji mutu fisik.
Pengaruh Perbedaan Metode Ekstraksi Maceration dan Microwave Assisted Extraction (MAE) Terhadap Penetapan Kadar Flavonoid Total Buah Ara (Ficus racemosa L.) Andry, Muhammad; Ligo, Azzura; Anggi, Reza Destri; Pradita, Diding; Luthvia, Luthvia; Nasution, Muhammad Amin; Pertiwi, Nia Novranda; Arifin, Arfiani
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.859

Abstract

Figs (Ficus racemosa L.) are an essential source of bioactive components such as phenols, terpenoids, flavonoids, and alkaloids with antioxidant properties. Two extraction methods are used to extract flavonoids from figs: conventional and non-conventional. This study aimed to determine the effect of different extraction methods—maceration and Microwave Assisted Extraction (MAE)—on the total flavonoid content in figs (Ficus racemosa L.). The research was conducted using a laboratory experimental method. The procedures included collecting and preparing plant materials, producing simplicia, evaluating simplicia characteristics, conducting phytochemical screening, preparing extracts, and determining total flavonoid content. The results showed that the maximum wavelength of quercetin was 438 nm, with a regression equation of Y = 0.0669x + 0.0084. The average absorbance values of fig extract using the maceration method were 0.216 with methanol, while the MAE method was 0.280 with methanol. The average percentage of flavonoid content using the maceration method was 0.1245% with methanol, while with the MAE method, it was 0.1623% with methanol. The total flavonoid content of fig extract using the maceration method was 1.2451 mgQE/g extract with methanol, while with the MAE method, it was 1.6238 mgQE/g extract with methanol. The study concluded that the highest total flavonoid content was found in the methanol extract obtained through MAE. This extract had a value of 1.6238 mgQE/g extract.
FORMULASI DAN UJI STABILITAS FISIK MASKER GEL PEEL OFF EKSTRAK METANOL ALGA MERAH (Eucheuma cottonii) VARIASI KONSENTRASI POLIVINIL ALKOHOL (FILM FORMING) Arifin, Arfiani
Jurnal Farmasi (Journal of Pharmacy) Vol 14, No 1 (2025)
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v14i1.312

Abstract

Red algae is a type of seaweed that has many biological activities. One of the compounds that acts as an antioxidant from red algae is phenolic compounds. The aim of this research is to determine the optimal concentration of polyvinyl alcohol to produce a red algae (Eucheuma cottonii) methanol extract peel-off gel mask that meets the physical stability test requirements. The extraction method used is maceration using methanol solvent. The formulation was made using varying concentrations of PVA FI (8%), FII (9%) and FIII (10%). Based on the research results, it was found that the most optimal PVA concentration and fulfilled the physical stability test requirements before and after storage was obtained at FIII with a PVA concentration (10%).