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Preparation and Characterization of Binahong (Anredera cordifolia) Leaf Extract Transfersome Wound-Healing Gel Immanuel, Handika; Yuliani, Sri Hartati; Dwiastuti, Rini; Nugraha, Alvin Arya; Limianty, Angela; Annabel, Evangeline Keisha; Lu, Felisha; Lestari, Fajar Sri; Branitasandini, Regina Epiphania
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 1 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007311

Abstract

Burn injuries are a significant global health concern due to their profound impact on morbidity and mortality rates. Immediate medical care is essential given the potential for bacterial infections to complicated burn injuries. Binahong leaves (Anredera cordifolia (Ten.) Steenis) contain vitexin compounds that demonstrate wound healing and antibacterial potential. However, vitexin has low solubility, prompting the use of ethanol for extraction and the introduction of nanoparticle technology to enhance solubility, namely transfersomes. The present study explored the development of a gel using binahong extract transfersomes with the composition of carbopol 940 and Na-CMC to determine the effect of carbopol 940, Na-CMC, and the interaction of the two on the gel’s physical properties and stability as well as obtain the optimum composition of the two. This study demonstrates positive results in terms of gel physical properties, including pH, spreadability, and viscosity. A Factorial design method is used for optimization. The results showed that Na-CMC had the most effect on increasing viscosity, while carbopol 940 had the most effect on reducing spreadability. The optimal formula obtained in this research was to use 0.653 grams of Na-CMC and 4.391 grams of Carbopol as gelling agents. 
Potensi Limbah Penebangan dan Pola Bentuk Penampang Tunggak Pohon pada Kegiatan Pemanenan Kayu di Hutan Alam Produksi Kalimantan Tengah: The Potential of Logging Waste and the Cross-Sectional Shape Patterns of Tree Stumps in Timber Harvesting Activities in Production Forests in Central Kalimantan Imanuel, Ricky Tri; Junaedi, Ajun; Yosep, Yosep; Dwiastuti, Rini; Yanciluk, Yanciluk; Rizal, Moh
JURNAL HUTAN TROPIKA Vol 20 No 2 (2025): Volume 20 Nomor 2 Tahun 2025
Publisher : Jurusan Kehutanan, Fakultas Pertanian Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36873/jht.v20i2.23189

Abstract

The objectives of this study were (a) to calculate the volume, percentage, and potential of tree felling waste; and (b) to identify the cross-sectional patterns of tree stumps in timber harvesting activities in the production forests of Central Kalimantan. Measurements of logging waste and observations of tree stump cross-sectional shapes were carried out on 60 predetermined sample trees located within 10 observation plots (10 ha). The results showed that the volume of logging waste was 106.42 m3 or 31.82% with a waste potential of 10.64 m3/ha. The patterns of stump cross-sections found in the logging plots consisted of several shapes, namely: star-shaped, triangular, round, irregular round, and square.
Implementasi Program Edukasi Pembuatan Ovitrap untuk Mengendalikan Persebaran DBD di Desa Kepek Kabupaten Gunung Kidul Dwiastuti, Rini; Wira Waskitha, Stephanus Satria; Setyaningsih, Dewi; Estyaningrum, Immanuela Putri Maharani; Simamora, Santika Ria Br; Graselia, Dena; Sihombing, Indri Andini; Pasa, Lidwina Vivi Reinha
Jurnal Pengabdian Kesehatan Vol 8, No 4 (2025): Jurnal Pengabdian Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM) STIKES Cendekia Utama Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31596/jpk.v8i4.587

Abstract

Demam berdarah dengue (DBD) merupakan penyakit yang disebabkan oleh infeksi virus dengue yang ditularkan oleh nyamuk berjenis Aedes aegypti dan Aedes albopictus. Penyakit ini telah menjadi permasalahan kesehatan serius di beberapa wilayah di Indonesia, terutama di Kabupaten Gunung Kidul. Kabupaten ini telah ditinjau dalam mengupayakan penurunan angka kasus penderita DBD, terutama di Kecamatan Wonosari. Tujuan dari penelitian dan pengabdian kepada masyarakat ini adalah memberikan edukasi pencegahan DBD dan pelatihan pembuatan ovitrap sederhana kepada masyarakat di Desa Kepek, Wonosari, Gunung Kidul. Metode yang digunakan pada kegiatan ini adalah pemberian edukasi oleh dosen dari Fakultas Farmasi Universitas Sanata Dharma (FF USD) dan kader kesehatan dari Puskesmas Wonosari II. Evaluasi peningkatan pemahaman peserta dilakukan menggunakan nilai pre-test dan post-test yang diperoleh peserta selama sebelum dan sesudah pemaparan edukasi. Kegiatan dilanjutkan dengan pelatihan pembuatan ovitrap sederhana oleh peserta. Hasil pelaksanaan kegiatan menunjukkan bahwa tidak ada perbedaan nilai rata-rata antara nilai pre-test dan post-test yang didukung melalui pendekatan statisika uji t berpasangan (paired-t test) dengan tingkat kepercayaan sebesar 95%. Penelitian ini menduga bahwa peserta telah miliki pemahaman dasar terkait pencegahan DBD dan penerapan ovitrap sebelum pemberian edukasi diberikan yang ditunjukkan dengan relatif tingginya nilai rata-rata pre-test yang diperoleh. Meskipun demikian, kegiatan ini memiliki dampak dalam meningkatkan kesadaran masyarakat dalam mengupayakan penurunan angka kasus DBD melalui pendekatan yang sederhana. Kegiatan ini menyoroti bahwa kolaborasi antara FF USD dengan Puskesmas Wonosari II memiliki potensi program yang keberlanjutan dalam menurunkan angka kasus DBD di Gunung Kidul, khususnya di Desa Kepek.
PENGARUH KUALITAS PELAYANAN TERHADAP LOYALITAS PASIEN RAWAT JALAN RUMAH SAKIT LUDIRA HUSADA TAMA YOGYAKARTA: - Primantana, Y.B. Arya; Dwiastuti, Rini
Jurnal Farmasi & Sains Indonesia Vol 8 No 2 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no2p92-99

Abstract

This study analyzes the effect of service quality on outpatient loyalty through patient satisfaction at RS Ludira Husada Tama Yogyakarta. Using purposive sampling, 150 outpatients completed SERVQUAL-based questionnaires analyzed with SEM-PLS. Results showed that tangible (p=0.017) and assurance (p=0.002) dimensions significantly influenced patient satisfaction, while reliability (p=0.554), responsiveness (p=0.646), and empathy (p=0.902) did not. Patient satisfaction significantly influenced loyalty (p=0.001). The findings indicate that physical facilities and service assurance are critical factors in building patient loyalty through satisfaction in outpatient settings.. Keywords: service quality, patient satisfaction, patient loyalty, outpatient, SERVQUAL