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All Journal Pharmaciana: Jurnal Kefarmasian Dharmakarya : Jurnal Aplikasi Ipteks Untuk Masyarakat Pharmacon PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) CERATA Jurnal Ilmu Farmasi Community Empowerment Sasambo Journal of Pharmacy Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Farmasi Sains dan Praktis Urecol Journal. Part C: Health Sciences Borobudur Pharmacy Review
Tiara Mega Kusuma
Universitas Muhammadiyah Magelang, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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HPLC DETERMINATION OF BENZOXAZOLINONE ON JERUJU PLANT (ACANTHUS ILICIFOLIUS): NARRATIVE REVIEW Nurul Umi Salamah; Imron Wahyu Hidayat; Tiara Mega Kusuma; Heni Setyowati Esti Rahayu; Prasojo Pribadi
Jurnal Farmasi Sains dan Praktis Vol 9 No 1 (January-April 2023)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v9i1.7186

Abstract

Mangrove plants in Indonesia are the largest in the world, both in terms of area quantity (+42,550 km2) and number of species (+45 species). Mangroves are a diverse group of salt tolerant plants that grow in intertidal tropical and subtropical forests and represent a rich biodiversity of plants, animals and microorganisms. Acanthus ilicifolius is one of the true mangrove plants which is used as medicine. This literature review aims to determine the study of benzoxazolinone compounds in jeruju plants (Acanthus ilicifolius) from previous studies and to determine the methods, plant parts and solvents used. The literature review method related to the jeruju plant (Acanthus ilicifolius) uses an electronic data base google scholar. Nuclear Magnetic Resonance (NMR) spectroscopy analysis method is one of the spectroscopic methods widely used in previous studies, because NMR spectroscopy is useful in determining the structure of a chemical compound, both proton (1H) and carbon (13C) NMR. Jeruju leaf extract contains alkaloids, flavonoids, polyphenols, phenyletanoid glycosides and coumarin compounds. The methanol fraction of jeruju leaf extract has a pharmacological effect to inhibit edema (inflammation). The extraction method used is maceration, because this method is simple method and most widely used. Meanwhile, the solvents that are more widely used are methanol and ethanol solvents.
Formulasi dan uji hedonik lilin aromaterapi minyak atsiri lengkuas (Alpinia galanga (L) Wild) Fatma Nurul Isma; Puspita Septie Dianita; Tiara Mega Kusuma
Borobudur Pharmacy Review Vol 3 No 1 (2023): January- June
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v3i1.7596

Abstract

Aromaterapi merupakan salah satu terapi komplementer yang menggunakan minyak atsiri sebagai pengobatan. Minyak atsiri dapat dibuat sebagai sediaan lilin aromaterapi. Pada penelitian sebelumnya disebutkan bahwa lengkuas memiliki efek menurunkan berat badan dengan cara inhalasi. Penelitian ini bertujuan untuk mengetahui formula lilin aromaterapi yang tepat, sifat karakteristik, tingkat kesukaan dan efek terapi yang dihasilkan oleh lilin aromaterapi lengkuas. Sediaan lilin aromaterapi diformulasi dengan bahan aktif minyak atsiri lengkuas konsentrasi 0%, 1%, 2%, dan 3%, menggunakan variasi komposisi basis lilin stearin dan paraffin 1:3; 1:1; dan 3:1, kemudian dilakukan evaluasi fisik sediaan lilin aromaterapi dengan uji organoleptik, uji titik leleh, uji waktu bakar, dan uji ketahanan aroma. Sedangkan untuk uji hedonik dilakukan dengan 20 panelis dengan uji penampakan secara keseluruhan, uji kesukaan terhadap lilin sebelum dan setelah dibakar, uji deteksi aroma pertama kali dan uji efek terapi yang dirasakan. Hasil evaluasi sediaan lilin aromaterapi berpengaruh terhadapi sifat fisik lilin aromaterapi. Berdasarkan hasil evaluasi sifat fisik, formula F5, F8, dan F11 memiliki sifat fisik dan tampilan yang baik. Uji hedonik yang dilakukan menunjukkan bahwa panelis paling menyukai lilin aromaterapi lengkuas dengan formula F11. Deteksi aroma pertama kali tercium dengan waktu tercepat antara 41-60 detik, pada formula F11.
Product Development of Anti Acne Gel: Combination of White Turmeric Rhizome Ethanol Extract (Curcuma Mango Val) and Galangal Rhizome Ethanol Extract (Alpinia Galanga) Imron Wahyu Hidayat; Retna Tri Astuti; Tiara Mega Kusuma
Urecol Journal. Part C: Health Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53017/ujhs.42

Abstract

White turmeric rhizome (Curcuma mango Val) and galangal rhizome (Alpinia galanga) have been widely studied to have antibacterial activity. One of the causes of acne is bacteria, such as Staphylococcus epidermidis. The purpose of this study was to determine the minimum inhibitory concentration of the ethanol extract of white turmeric (Curcuma mangga Val) and galangal (Alpinia galanga) rhizome against acne-causing bacteria and its effectiveness after it was formulated in gel form. Simplicia was extracted by maceration method using ethanol 96% solvent. The extract was formulated in the form of a gel with various concentrations of CMC Na. The results of the gel antibacterial evaluation showed that the ethanol extract gel of white turmeric rhizome (Curcuma mangga Val) and galangal rhizome (Alpinia galangal) showed antibacterial activity against S. epidermidis bacteria.
Qualitative and quantitative analysis of prednisone chemical content in rheumatic herbs in Magelang Region Afifah, Riza Nur; Wardani, Arief Kusuma; Kusuma, Tiara Mega
Sasambo Journal of Pharmacy Vol. 6 No. 1 (2025): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v6i1.358

Abstract

Currently, there is a phenomenon that shows that many herbs consumed by the public contain medicinal chemicals (BKO). This study aims to identify the presence of BKO prednisone in rheumatic herbs and its levels. This study took five types of samples of rheumatic herbs in Magelang area with different brands, namely samples of herbs A, B, C, D and E, which are available in capsule and powder form. Identification of prednisone in rheumatic herbs was carried out using thin layer chromatography (TLC) method with silica gel GF254 as stationary phase and ethyl acetate: chloroform mixture (4:1) as mobile phase. Quantitative analysis was performed using UV-Vis spectrophotometry with a maximum wavelength of 238.5 nm. The rf value of prednisone standard 0.42 was obtained and quantitative analysis showed that the prednisone content in sample B in the first replication was 3.22%, in the second replication was 2.18%, in the third replication was 2.23%.
Co-Authors A.A. Ketut Agung Cahyawan W Afifah, Riza Nur Agusta, Herma Fanani Astuti, Fitriana Yulia Azalea, Metty Diah Kartika Dianita, Puspita Dwi Anggraeni Candrawati, Ira Endaryanti Wulandari Fatma Nurul Isma Fitriana Yulia Astuti Fitriana Yuliastuti Hapsari, Widarika Santi Hariyani Hariyani Hariyani, Hariyani Heni Lutfiyati Heni Lutfiyati Heni Lutfiyati, Heni Heni Setyowati Esti Rahayu Heri Susanto Heri Susanto Hesti Krisnaningtyas Hesti Krisnaningtyas, Hesti Hidayat, Imron Wahyu Imron Wahyu Hidayat Imron Wahyu Hidayat Ira Dwi Anggraeni Candrawati Ira Dwi Anggraeni Candrawati, Ira Dwi Anggraeni Kartika, Diah Metty Azalea Naily Syifa Nurul Umi Salamah Nurul Uswatun Nurul Uswatun, Nurul Prabandaru Esthi Pudyawanti Prasojo Pribadi Puspita Dianita Puspita Septie Dianita Puspita Septie Dianita, Puspita Septie Raudina Rusy, Irsalina Retna Tri Astuti Santoso, Setiyo Budi Septi Wardani Syifa, Naily Taufik Widiyanto Wardani, Arief Kusuma Wardani, Septie Widiyanto, Taufik Wulandari, Endaryanti