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All Journal International Journal of Public Health Science (IJPHS) International Journal of Evaluation and Research in Education (IJERE) Jurnal Pendidikan Sosiologi dan Humaniora Jurnal Vektor Penyakit Jurnal Administrasi Kesehatan Indonesia Journal of Agromedicine and Medical Sciences IJNP (Indonesian Journal of Nursing Practices) Jurnal Gizi Klinik Indonesia Jurnal Kreativitas PKM Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Majalah Kedokteran Andalas JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Cermin Dunia Kedokteran Jurnal Teknologi Lingkungan Lahan Basah Berita Kedokteran Masyarakat Jurnal Abdi Kesehatan dan Kedokteran Jurnal Penyakit Dalam Indonesia Jurnal Vokasi Kesehatan Biomedika Cermin Dunia Kedokteran
Agustina Arundina Triharja Tejoyuwono, Agustina Arundina Triharja
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Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : Biomedika

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EVALUATION OF HEMOGLOBIN LEVELS, ERYTHROCYTE INDEX, AND MENTZER INDEX FOR EARLY DETECTION OF ANEMIA AND THALASSEMIA MINOR IN JUNIOR HIGH SCHOOL Fitrianingrum, Iit; Tejoyuwono, Agustina Arundina Triharja; Windarti, Wiwik
Biomedika Vol 17, No 2 (2025): Biomedika August 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v17i2.10566

Abstract

Introduction: Thalassemia and iron deficiency anemia (IDA) are two of the most common causes of microcytic anemia worldwide, particularly in developing countries. This study was conducted to analyze hematological parameters and apply the Mentzer Index among junior high school students in Pontianak, Indonesia, in order to identify suspected cases of thalassemia trait and IDA, and to assess the feasibility of using Mentzer Index as a preliminary screening tool in this setting. Methods: A cross-sectional study was conducted involving 50 students (aged 13-17 years) who underwent complete blood count (CBC) testing. Parameters included hemoglobin (Hb), erythrocyte count, MCV, MCH, MCHC, RDW and Mentzer Index. An MI <13 was interpreted as suggestive of thalassemia trait, while MI ≥ 13 indicated possible IDA or normal findings Results: Among the participants, 6 students (11,5%) had MI < 13, consistent with suspected thalassemia minor. Several others showed anemia with MI ≥ 13 and elevated RDW, suggestive of IDA. Girls were more frequently affected by anemia-related abnormalities. Overall, microcytosis (MCV < 80 fL), hypochromia (MCH <27 pg) and high RDW were commonly observed Conclusion: A notable proportion of students screened exhibited hematological indicators of thalassemia trait and IDA. The Mentzer Index, combined with CBC parameters, proved effective in initial differentiation. Early school-based screening is essential for timely diagnosis, management, and genetic counseling in at-risk populations.
Co-Authors -, Chelsia Abror Irsan Armyanti, Ita AS, Ismi Wulandari Asseggaf, Syarifah Nurul Yanti Rizki Syahab Carla Jean Marshellina Chelsia - Delima Fajar Liana Desriani Lestari Diana Natalia Eka Ardiani Putri Fatin Mawaddah Fitri Fujiana Handini, Mitra Ismi Wulandari AS Jessica Juniarta Sihombing Jessica Juniarta Sihombing Joni Tampe Parinding Lisma Evareny, Mohammad Hakimi, Retna Siwi Padmawati Mardhia, Mardhia Mellinia Wahyu Nurliesa Muhammad Asroruddin, Muhammad Muhammad Riedha Nadya Eulalia Nurmainah Nurmainah Nursyifa, Salsabila Pramadita, Suci Putri, Eka Ardiani Putri, Eka Ardiani Rahmat Satriadi Ramadhina, Saffana Fadhilla Rangga Putra Nugraha Retna Siwi Padmawati Sari Eka Pratiwi Silaban, Agatha Sintan, Teofilus Sri Adiningsih Sri Purwanti Sri Purwanti Syarifah Nurul Yanti R.S.A Tamara Septia Chairunisa Toto Sudargo Toto Sudargo Tri Wahyudi Virgilius Phasacola Tiko Kafaso Wilson Wilson Windarti, Wiwik Wiwik Windarti Z, Khafifah