Garuda - Garba Rujukan Digital

p-Index From 2021 - 2026

1.704

P-Index

This Author published in this journals

All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN MEDIA MEDIKA INDONESIANA ODONTO Dental Journal Mutiara Medika: Jurnal Kedokteran dan Kesehatan Biomedika Universa Medicina Media Medika Muda Jurnal Ilmu Kedokteran dan Kesehatan Medica Hospitalia Medica Arteriana (Med-Art) Diponegoro International Medical Journal (DIMJ) Life Science Odonto dental journal Folia Medica Indonesiana

Udadi Sadhana, Udadi

Anatomical Pathology Department Of Medical Faculty Of Diponegoro University

Author-ID : 500148

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

Published : 25 Documents Claim Missing Document

Claim Missing Document

Articles

Title

Ekspresi Reseptor Estrogen, Reseptor Progesteron Dan Digit Ratio Pada Pasien Meningioma Prakoso, Teguh Iman; Arifin, Mohammad Thohar; Sadhana, Udadi; Puspasari, Dik; Kusuma Astuti, Meira Dewi
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 2 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar belakang Meningioma merupakan tumor jinak intrakranial primer yang dipengaruhi oleh keseimbangan hormon estrogen dan progesteron. Digit Ratio (2D : 4D) sangat dipengaruhi oleh paparan hormon androgen prenatal khususnya estrogen dan testosteron. Tujuan Mengetahui hubungan reseptor estrogen (ER) dan reseptor progesteron (PR) dengan Digit Ratio (2D : 4D) pada pasien meningioma. Metode Penelitian observasional analitik dengan desain cross sectional study. Jumlah sampel sebesar 25 pasien meningioma yang dilakukan pemeriksaan ER dan PR. Pengukuran Digit Ratio dilakukan di poliklinik dan bangsal bedah syaraf RSUP Dr. Kariadi Semarang. Uji statistik menggunakan uji spearman. Hasil Digit Ratio kanan, kiri dan selisih kanan-kiri dengan nilai rerata 1,0046; 1,0021 dan 0,0492. Uji spearman, hubungan Digit Ratio kanan, Digit Ratio kiri dan Selisih Digit Ratio kanan kiri dengan PR didapatkan masin–masing nilai p = 0,5 (r = 0,1), p = 0,8 ( r = 0,1), dan p = 0,3 (r = 0,2). Hubungan Digit Ratio kanan, Digit Ratio kiri dan Selisih Digit Ratio kanan kiri dengan ER didapatkan masing–masing nilai p = 0,4 (r = 0,2), p = 0,5 ( r = -0,1), dan p = 0,9 (r = 0,1). Secara statistik terdapat hubungan yang sangat lemah antara Digit Ratio kanan, Digit Ratio kiri, selisih Digit Ratio kanan kiri dengan ER dan PR pada pasien meningioma Simpulan Terdapat hubungan yang sangat lemah antara reseptor estrogen (ER) dan reseptor progesteron (PR) dengan Digit Ratio pada pasien meningioma. Kata kunci : Reseptor Estrogen, Reseptor Progesteron, Digit Ratio, Meningioma. Background Meningiomas are primary intracranial benign tumors that are affected by the balance of estrogen and progesterone. Digit Ratio (2D: 4D) is strongly influenced by exposure to prenatal androgen hormones especially estrogen and testosterone. Objective To determine the relationship between estrogen receptor (ER) and progesterone receptor (PR) with Digit Ratio (2D: 4D) in meningioma patients. Method Analytical observational research with cross-sectional study design. The total sample of 25 meningioma patients who underwent ER and PR examinations. Digit Ratio measurements were performed at the clinic and neurosurgical ward of RSUP Dr. Kariadi Semarang. The Spearman test was used for the statistical test. Results Right, left and right-left difference digit ratio with mean value of 1.0046; 1,0021 and 0,0492. After Spearman test, the relationship between right Digit Ratio, left Digit Ratio and Difference between right and left Digit Ratio with PR was p = 0.5 (r = 0.1), p = 0.8 (r = 0.1), and p = 0.3 (r = 0.2). Correlation between right Digit Ratio, left Digit Ratio and Difference between left and right Digit Ratio with ER was p = 0.4 (r = 0.2), p = 0.5 (r = -0.1), and p = 0.9 (r = 0.1). Statistically there is a very weak relationship between right Digit Ratio, left Digit Ratio, difference between right and left Digit Ratio with ER and PR in patients with meningiomas. Conclusions There is a very weak relationship between estrogen receptors (ER) and progesterone receptors (PR) and Digit Ratio in meningioma patient. Keywords: Estrogen Receptor, Progesterone Receptor, Digit Ratio, Meningioma.

Schneiderian Carcinoma Apriana, Ledisda; Sadhana, Udadi; Wijaya, Indra; Karlowee, Vega
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 2 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar Belakang: Squamous Cell Carcinoma (SCC) adalah keganasan paling umum dari kepala dan leher (sekitar 3%), tetapi hanya <1% dari seluruh jenis keganasan (insidensi jarang), yang dibagi menjadi jenis keratinizing dan non-keratinizing. Nonkeratinizing squamous cell carcinoma mempunyai berbagai nama lain, salah satunya Schneiderian carcinoma. Dahulu, Schneiderian carcinoma disebut sebagai Carcinoma Ex-Schneiderian Papilloma (malignant transformation). Atas kelangkaan dan keberagaman penamaan kasus ini, maka penulis tertarik untuk menyajikan kasus ini. Laporan Kasus: Seorang laki-laki 68 tahun datang dengan keluhan utama benjolan di leher kanan. Dilakukan tindakan wide eksisi dan rekontruksi, kemudian dikirimkan sampel untuk pemeriksaan histopatologi, didapatkan gambaran kelompok-kelompok sel epithelial ganas, dengan inti bulat oval, pleomorfik, hiperkromatik, berkromatin kasar, sitoplasma eosinofilik, mitosis dapat ditemukan, tumbuh papilifer, infiltratif diantara dalam stroma jaringan ikat fibrous. Dilakukan pemeriksaan lanjutan dengan pengecatan imunohistokimia yang memberikan hasil: CK5/6 positif, P63 positif, dan Ki67 positif > 80%. Diskusi: Ciri dan gejala pada pasien ini sesuai dengan kekhasan epidemiologi berdasarkan literatur. Berdasarkan pemeriksaan histopatologis dan pulasan imunohistokimia menyokong diagnosis Squamous cell carcinoma, transisional differenteated (Schneiderian carcinoma) regio colli sisi dekstra. Kesimpulan: Pemeriksaan histopatologi dan imunohistokimia pada kasus Schneiderian carcinoma ini menjadi penting serta harus dibedakan dengan jenis lainnya karena masing-masing manajemen dan prognosisnya pun berbeda. Kata Kunci: Schneiderian carcinoma, nonkeratinizing squamous cell carcinoma, transisional differenteated, Carcinoma Ex-Schneiderian Papilloma. Background: Squamous Cell Carcinoma (SCC) is rare, accounting for <1% of malignant tumours and only about 3% of malignancies of the head and neck, that includes a keratinizing and a non keratinizing type. Nonkeratinizing squamous cell carcinoma has various other names, which one is Schneiderian carcinoma. In the past, Schneiderian carcinoma was referred to as Carcinoma Ex Schneiderian Papilloma (Malignant Transformation). Based on the scarcity and diversity of naming these cases, the authors are interested to presenting this case. Case Description: A 68-year-old man comes with a complaint of a lump in the right neck. Wide excision and reconstruction were carried out, then samples were sent for histopathology, a description of malignant epithelial cell groups, with oval, pleomorphic, hyperchromatic, coarse chromatin nuclei, eosinophilic cytoplasm, mitosis can be found, papilliferous growth, infiltrative within the tissue fibrous stroma. Follow-up examination with immunohistochemical staining that gave results: CK5/6 positive, P63 positive, and Ki67 >80%. Discussion: Characteristics and symptoms in these patients are consistent with epidemiological characteristics based on literature. Based on histopathological and immunohistochemical examination support to diagnosis Squamous cell carcinoma, transitional differenteated (Schneiderian carcinoma) in colli region right side. Conclusion: Histopathology and immunohistochemistry examination in the case of Schneiderian carcinoma are important and must be distinguished from other types because each management and prognosis are different. Keywords: Schneiderian carcinoma, nonkeratinizing squamous cell carcinoma, transisional differenteated, Carcinoma Ex-Schneiderian Papilloma.

Comparing the Pulmonary-Spirometry In Laboratory Workers Who Wear Acchadana® and KN95® Masks Nurkholis, Fathur; Ariani, Resti; Prasetyo, Awal; Puspita`, Rina; Sadhana, Udadi; Miranti, Ika Pawitra; Istiadi, Hermawan
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 2 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i2.1076

BACKGROUND : The upper respiratory tract is susceptible to inflammation caused by exposure to airborne contaminants, particularly chemical irritants. Inhaled irritant gases can lead to various symptoms and adverse reactions in the respiratory tract. Laboratory workers are at a high risk of respiratory tract inflammation due to exposure to volatile chemicals. The use of personal protective equipment (PPE), such as masks, is essential to prevent inflammation and protect the respiratory tract. Lung function tests using spirometry, including Forced Vital Capacity (FVC), Forced Expiratory Volume in One Second (FEV1.0), and Peak Expiratory Flow (PEF), can help identify abnormalities in lung function. AIMS : The primary objective of this investigation is to juxtapose the pulmonary conditions of laboratory workers before and after the utilization of KN95® masks and Acchadana® masks. METHOD : The study design was a Randomized Control Trial, and the subjects were divided into two groups: the control group wearing KN95 masks and the treatment group wearing Acchadana® herbal masks. Spirometry measurements were taken before and after using the masks, and statistical analysis was conducted to compare the results. RESULT : The results showed that both mask groups experienced improvements in lung function parameters after using the masks. However, the KN95 mask group showed better lung conditions compared to the Acchadana® mask group. CONCLUSION : Spirometry tests conducted on lab workers revealed improved lung function metrics (including FVC, FEV1.0, and PEF) following the usage of KN95 masks and Acchadana® herbal masks. The KN95 mask users exhibited superior respiratory health compared to the other group in this investigation.

Co-Authors , Yan Wisnu Prajoko A.A. Ketut Agung Cahyawan W AA Sudharmawan, AA Aminuyati Antari, Arlita Leniseptaria Apriana, Ledisda Ariani, Resti Asri, Hairul Atikah Atikah Awal Prasetyo Bambang Hendro Putranto, Bambang Hendro Devia Eka Dik Puspasari Dik Puspasari Dik Puspasari, Dik Djamila Zakaria Dwi Pudjonarko Edy Prasetyo Endang Mahati Eny Dyah Kurniawati, Eny Dyah Hamidiyah, Silpi Hapsari Galih Setyowati Hermawan Istiadi Ika Pawitra Miranti Indra Widjaya Karlowee, Vega Kusuma Astuti, Meira Dewi Lestari, Nadia Nur Lina Damayanti, Lina M Naharuddin Jenie Maftikhati, Dora Malik, Ricat Hinaywan Maryam Restiwijaya Meira Dewi Kusuma Meira Dewi Kusuma Astuti Mohammad Thohar Arifin, Mohammad Thohar Muhammad Nur Nani Maharani Neni Susilaningsih Ningtyas, Endah Ariyati Eko Novit, Elmawati Nurkholis, Fathur Oedijani Santoso Prakoso, Teguh Iman Prastyo K, Yuni Prihharsanti, Christina H.N. Puspita`, Rina Rahajeng, Herera RR. Ella Evrita Hestiandari Selamat Budijitno Siti Sunarintyas Susilorini Susilorini, Susilorini Tri Nur Kristina Utami, Widoasti Putri Vega Karlowee Winarto Winarto Yan Wisnu Prajoko

Title Search

Found 3 Documents Search Journal : Medica Hospitalia

Abstract

Abstract

Abstract

Title

Found 3 Documents
Search
Journal : Medica Hospitalia