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The Relationship Between Tumor Size Parameters and Carcinoembryonic Antigen (CEA) Levels in Colorectal Adenocarcinoma Based on Contrast-Enhanced Abdominal CT Scan Prasatya, Dewa Putu Jaya; Margiani, Ni Nyoman; Wijaya, I Gusti Agung Gede Mahendra; Putra, I Wayan Gede Artawan Eka
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 19 No 1 (2025): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan (In Press)
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v19i1.12265

Abstract

Introduction: Colorectal adenocarcinoma is a common malignancy with high mortality. Carcinoembryonic Antigen (CEA) is widely used as a tumor marker, while contrast-enhanced CT scans provide tumor size parameters. The correlation between these parameters and CEA remains unclear. Objective: To analyze the relationship between tumor area and thickness on contrast-enhanced CT scan and CEA levels in colorectal adenocarcinoma. Methods: A retrospective cross-sectional study was conducted at RSUP Prof. Dr. I.G.N.G. Ngoerah (2018–2023) involving patients with available CT scan and CEA data. Pearson correlation and multivariate regression were applied. Results: Tumor area showed a significant positive correlation with CEA (r = 0.513; p = 0.001), independent of age and sex. Tumor thickness was not significantly correlated (r = 0.196; p = 0.224). Conclusion: Tumor area correlates significantly with CEA levels, whereas tumor thickness does not. Tumor area may serve as an additional indicator in colorectal cancer evaluation.
Investigating a DHF Outbreak in Batuan Village, Gianyar Lahari, Ni Luh Putu Sri; Putra, I Wayan Gede Artawan Eka; Septarini, Ni Wayan
Basic and Applied Nursing Research Journal Vol. 6 No. 2 (2025): Basic and Applied Nursing Research Journal (BANRJ)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/banrj.06.02.02

Abstract

Background: In March–April 2025, an unusual increase in Dengue Hemorrhagic Fever (DHF) cases was reported in Banjar Dentiyis, Batuan Village, Sukawati District, Gianyar, Bali. The case count rose from 8 in the previous year to 20 within two months, including one death. The sharp increase in incidence and mortality met the criteria for a Kejadian Luar Biasa (KLB), or outbreak, as defined by the Indonesian Ministry of Health. This investigation was conducted to characterize the outbreak, identify contributing risk factors, and evaluate the public health response. Objective: To determine the epidemiological profile and environmental risk factors associated with the DHF outbreak in Banjar Dentiyis and to provide recommendations for prevention and control. Methods: A descriptive cross-sectional investigation was carried out from April 4 to 30, 2025. Data collection included secondary surveillance data from Puskesmas Sukawati I and primary field investigations involving interviews, environmental inspections, and larval surveys. Cases were analyzed based on demographic characteristics, spatial distribution, temporal trends, and risk factors such as the presence of larvae and container density. Results: Twenty DHF cases and one death were confirmed, with the highest concentration (12 cases) in Gang Bunut, yielding an attack rate of 12.9% and a local CFR of 8.3%. Most patients were female (60%) and over the age of 15, although the highest attack rate (3.79%) occurred among children under 15. Clinical symptoms were consistent across cases, with all patients experiencing fever and most reporting headaches and nausea. Environmental assessment revealed mosquito larvae in 35% of case households, with bromeliad plants and uncovered containers serving as primary breeding sites. Fogging and vector control interventions were delayed and did not follow recommended intervals. Conclusion: The outbreak in Banjar Dentiyis highlights the need for timely response, routine vector surveillance, and sustained community engagement. Delays in fogging and inadequate container management contributed to the persistence of transmission. Strengthened preventive measures, improved health literacy, and adherence to dengue control protocols are critical to mitigating future outbreaks.
Co-Authors Agustina, Kristin Anak Ayu Sri Wahyuni, Anak Ayu Sri Ardi, Ni Made Septiari Maryani Ariani, Ni Ketut Putri Arista, I Gede Peri Astiti, Cokorda Istri Sri Dharma Ayusta, I Made Dwijaputra Ayustama, Fariza Cokorda Bagus Jaya Lesmana, Cokorda Bagus Jaya DAMARNEGARA, ANAK AGUNG NGURAH ANDIKA Dewa Nyoman Wirawan, Dewa Nyoman Dewi, Desak Putu Risna Dharmayuda, A.A Ngurah Gede Dyah Pradnyaparmita Duarsa Elysanti Dwi Martadiani Eveline, Ency Haryadi - Hesteria Friska Armynia Subratha I Gusti Agung Komang Diafari Djuni Hartawan I Gusti Agung Trisna Windiani I Made Dharma Atmaja I Nyoman Mangku Karmaya Juergens, Stefanie Karang, Ni Made Reyningrum Karminiasih, Ni Luh Putu Ketut Dewi Kumara Wati Ketut Tuti Parwati Merati Khrispina Owa Kurniawan, Lely Setyawati Lahari, Ni Luh Putu Sri Lestari, Kadek Susiana Dwi Luh Nyoman Alit Aryani, Luh Nyoman Alit Luh Seri Ani Made Widhi Asih MAHARDIKA, I KOMANG ANA Mahendra, I Gusti Agung Gede Merati, Tuti Parwati Mukti, Kezia Sondang Ni Ketut Noriani Ni Made Parwati Ni Nyoman Margiani Ni Wayan Septarini Nyoko, Yuneti Octavianus Pande Putu Januraga Pande Putu Yuli Anandasari Patriawan, Putu Pinatih, Gede Ngurah Indraguna Prasatya, Dewa Putu Jaya Putra, Made Surya Saptono Putu Ayu swandewi astuti Putu Ika Farmani R. A.T. Kuswardhani Rai, Ida Bagus Ngurah Rizki Yulia Purwitaningtyas, Rizki Yulia Sawitri, Anak Agung Sagung Sitanggang, Firman Parulian Sriwijayanti, Luh Putu Eka Suputra, Anak Agung Gede Widodo, Ivola Lita Widyartha, I Made Jaya Wijaya, I Gusti Agung Gede Mahendra Yatra, I Made Suganda Yuliani Yuliani