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All Journal Folia Medica Indonesiana Indonesian Journal of Tropical and Infectious Disease Oto Rhino Laryngologica Indonesiana JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Majalah Biomorfologi (Biomorphology Journal) Jurnal Layanan Masyarakat (Journal of Public Service) JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH Jurnal Pengabdian Masyarakat dalam Kesehatan Indian Journal of Forensic Medicine & Toxicology Asian Journal of Health Research eJournal Kedokteran Indonesia
Nyilo Purnami
Departement Of Otorhinolaryngology Head And Neck Surgery, Faculty Of Medicine, Universitas Airlangga, Surabaya, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Earth & Planetary Sciences Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Journal : eJournal Kedokteran Indonesia

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Factors Affecting Adverse Events Following SARS-CoV-2 Vaccine among Indonesian Ear, Nose, and Throat Specialist, and Residences Susyana Tamin; Jenny Bashiruddin; Indra Zachreini; Harim Priyono; Ika Dewi Mayangsari; Respati Ranakusuma; Natasha Supartono; Khoirul Anam; Anggina Diksita; Yussy Afriana Dewi; Sagung Rai Indrasari; Nyilo Purnami; Tengku Siti Hajar Haryuna; Juliandi Harahap; Eka Savitri; Tjandra Manukbua
eJournal Kedokteran Indonesia Vol. 10 No. 2 - Agustus 2022
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23886/ejki.10.165.129-37

Abstract

This study’s objectives were to investigate factors affecting the adverse events of the COVID-19 vaccine in Indonesia among health care workers and compare adverse events following SARS-CoV-2 vaccine using CoronaVac as the first and second dose and Moderna used as the booster third dose. A cross-sectional study was conducted using the Self-reporting Online Survey Platform (Google Form) from August to October 2021. Subjects included in the study were ENT specialists and residents all over Indonesia who had been vaccinated with both doses of CoronaVac COVID-19 vaccine and Moderna COVID-19 vaccine as a booster dose. Among a total of 1394 participants, 51.2% and 43.7% of subjects experienced adverse events following the first and second dose of the CoronaVac vaccine. Adverse events are significantly higher following the third dose of Moderna vaccine (95.3%) with p-value <0.001, odds ratio (OR) 26.63 (95% CI 19.87-35.7). Adverse events following the CoronaVac vaccine were significantly higher in females and individuals with comorbidities in the first dose (p=0.002 and p=0.04), and the second dose (p=0.008 and p=0.042). Adverse events following the Moderna vaccine were significantly higher in females (p=0.01) and lower in individuals ≥40 years of age (p=0.017). Comorbidity status did not affect adverse events following the Moderna vaccine. Keywords: adverse events, SARS-CoV-2, COVID-19, vaccine, otorhinolaryngology.   Faktor yang Mempengaruhi Efek Samping Vaksin SARS-CoV-2 terhadap Dokter Spesialis dan Residen Telinga, Hidung, dan Tenggorok di Indonesia Abstrak Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi efek samping vaksin COVID-19 di Indonesia pada petugas kesehatan dan membandingkan efek samping setelah vaksin SARS-CoV-2 menggunakan CoronaVac sebagai dosis pertama dan kedua dan Moderna sebagai booster dosis ketiga. Studi potong lintang dilakukan dengan menggunakan self-reporting survei online (Google Form) dari Agustus-Oktober 2021. Subjek yang termasuk dalam penelitian adalah dokter residen dan spesialis THT di Indonesia yang telah divaksinasi dengan kedua dosis vaksin CoronaVac COVID-19 dan vaksin Moderna COVID-19 sebagai dosis tambahan. Dari total 1394 peserta, 51,2% dan 43,7% subjek mengalami efek samping setelah dosis pertama dan kedua vaksin CoronaVac. Efek samping secara signifikan lebih tinggi setelah dosis ketiga vaksin Moderna (95,3%) dengan p-value <0,001, rasio odds (OR) 26,63 (95% CI 19,87-35,7). Efek samping setelah vaksin CoronaVac secara signifikan lebih tinggi pada wanita dan individu dengan penyakit penyerta pada dosis pertama (p=0,002 dan p=0,04), dan dosis kedua (p=0,008 dan p=0,042). Efek samping setelah vaksin Moderna secara signifikan lebih tinggi pada wanita (p=0,01), dan lebih rendah pada individu ≥ 40 tahun (p=0,017). Status komorbiditas tidak mempengaruhi efek samping setelah vaksin Moderna. Kata kunci: efek samping, SARS-CoV-2, COVID-19, vaksin, otorinolaringologi.
Co-Authors A Ratna Kartika M, A Ratna Ahmad Suryawan Ahyandi, Syarif Syamsi Airina, Andi Alda, Rieza Rizqy Aldri Frinaldi Alfarika Rosmalia Alfian nurfaizi Alfian Nurfaizi Alfian Nurfaizi Aminuyati Anggina Diksita Anita Nuraini Aristya, Meutia Putri artono artono Artono Artono, Artono Asmaradianti, Aryunidya Aulia Sakinah Awalia, Awalia Ayuning Tetirah Ramadhani Baiq Dwi Hadiatul Azni Belanny Dwi Desihartati Berliana Nur Azizah Bintang Napitupulu Brahmono, Aditya Budi Utomo Budi Utomo Cahyani, Makhmudyah Indri Chriscelia Valery So Chriscelia Valery So Cintya Dipta Crysciando Jefryco Putra Dewo Aksoro Eddy Bagus Wasito Edith Frederika, Edith Eka Savitri Eka Savitri Falerina, Rosa Fauzi Helmi Fikri Mirza Putranto Firdha, Azizah Amimathul Fis Citra Ariyanto Galih, Antonius Ghaus, Akbar Hamam, Kusumagani Haryuna, Tengku Siti Hajar Hendra Kurnia Rakhma Hendra Kurnia Rakhma I'tishom, Reny Ika Dewi Mayangsari Ilmi, Avida Marisa Inayasari, Syahwina Indira Syahraya Indra Zachreini Indra Zachreini Izzattisselim, Sabrina Jenny Bashiruddin Jenny Bashiruddin Juliandi Harahap Juliandi Harahap Kote Noordhianta Lelyana Sih Afgriyuspita Mahesya, Alvian Wahyu Mahrus A Rahman, Mahrus A Makhmudyah Indri Cahyani Makhmudyah Indri Cahyani Martono Martono Mayangsari, Ika Dewi Myrna Adianti Narottama, Kadek Rama Natasha Supartono Natasha Supartono Ni Made Adnya Suasti Nico Probosutejo Ninuk Dwi Ariningtyas Nugroho, Puguh Setyo Nuniek Nugraheni Nunuk Mardiana, Nunuk Nuraini, Anita Nuramalia, Lady Sherly Nurdiansyah, Achmad Fajar Putra Nurvita, Rani Nurwasis Nurwasis Paulus Liben, Paulus Perdana, Rizka Fathoni Prabowo, Gwenny Ichsan Pralampito, Fajrinka Priyono, Harim Probosutejo, Nico Pudji Lestari Puspa Wardhani Puspita, Dwi Indah Rahma, Safira Respati Ranakusuma Respati Ranakusuma Retno Handajani Risa Etika, Risa Rizka Fathoni Perdana Rizka Fathoni, Rizka Romdhoni, Achmad Chusnu Rosydiah Rahmawati, Rosydiah S.Pd. M Kes I Ketut Sudiana . Sabrina Izzattisselim Sagung Rai Indrasari Sagung Rai Indrasari Salsabila, Aisyah Nur Saputri, Faradila Budi Selfiyanti Bimantara Septriana, Maya Sholehen, Alif Sofia Tiarini Sri Herawati Sriati Sriati Suhariningsih Sulistiawati Sumarman Sumarman Surarso, Bakti Susyana Tamin Susyana Tamin Tiarini, Sofia Tjandra Manukbua Tjandra Manukbua Ummi Imamatal Muttaqin WINARTO Wungu, Citrawati Dyah Kencono Yoga Rahmadiyanto Yoga Rahmadiyanto Yoga Rahmadiyanto Yussy Afriana Dewi Yussy Afriana Dewi Zamrotu Iva Purwanti Zuhria, Ismi