Claim Missing Document
Check
Articles

Found 24 Documents
Search

ANTIBACTERIAL n-HEXANE EXTRACT OF Uncaria Gambir Roxb FROM PONTIANAK: ANTIBAKTERI EKSTRAK n-HEXANE Uncaria Gambir Roxb DARIPONTIANAK Desdy Hendra Gunawan; Iskandar, Dodi
ROCE : Jurnal Pertanian Terapan Vol. 2 No. 2 (2025): JPT ROCE 4, 2025
Publisher : PT. ROCE WISDOM ACEH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71275/roce.v2i2.134

Abstract

Staphylococcus aureus is a Gram-positive bacterium that can act as both a commensal and an opportunistic pathogen, causing a range of infections from superficial skin conditions to life-threatening illnesses. The emergence of antibiotic-resistant strains, such as MRSA, highlights the need for alternative or complementary natural antibacterials. This study aimed to evaluate the antibacterial potential of n-hexane extract of Uncaria gambir Roxb (UGR) leaves against S. aureus through both in silico prediction and in vitro testing. The compounds present in the leaves were identified using the Knapsack family database and analyzed for antibacterial activity using PASS Online, while solubilitywas predicted with SwissADME. In vitro antibacterial activity was determined using the agar diffusion method at six extract concentrations (5–40%), with 10% Chloramphenicol as a positive control and sterile distilled water as a negative control. Results indicated that metabolites such as Gallic acid, Cinchonain Ia, and Procyanidins B1 and B3 exhibited the highest predicted antibacterial probabilities,with solubility patterns suggesting better extraction in nonpolar solvents. The inhibition zone diameter generally increased with extract concentration, reaching a maximum of 10.76 ± 1.58 mm at 40%, confirming a concentration-dependent effect. However, the extract’s activity remained lower than that of Chloramphenicol (20.47 mm). Factors such as low compound concentration, limited solubility, chemical properties, and bacterial defense mechanisms likely contributed to the moderate inhibitory activity of the compound. Overall, the n-hexane extract of Uncaria gambir leaves demonstrates measurable antibacterial potential against S. aureus, supporting its traditional use and indicating its promise for further study as a natural antibacterial agent.
Efektivitas Program Sekolah Ramah Anak Dalam Mengembangkan Sekolah Berkarakter Iskandar, Dodi; Yuni Hendrowati, Tri; Siswoyo, Siswoyo
Manajemen Pendidikan Volume 19, No. 1, Tahun 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jmp.v19i1.4852

Abstract

The purpose of this study is to decrypt the implementation of the Child Friendly School program and develop the character of students at SD Negeri 1 Pulaupanggung Tanggamus. This study provides a comprehensive overview of child-friendly school programs. The child-friendly program is not just a program at SD Negeri 1 Pulaupanggung but the importance of a child-friendly seklah program for student character building since elementary school. This study intends to find an overview of child-friendly school programs both in terms of supporters and obstacles.at SD Negeri 1 Pulaupanggung This type of research is descriptive qualitative in assessing field phenomena that occur. The implementation of child-friendly school programs is carried out by means of interviews, observations, and documentation. The implementation of child-friendly programs is carried out in 4 steps, namely: (1) Child-friendly school policy programs; (2) Educators and education personnel trained in children's rights; (3) Implementation of a child-friendly learning process, the application of non-violent discipline; and a safe, comfortable and clean school environment; (4) Student participation in learning. Child-friendly school policy programs include programs carried out in collaboration with students in the classroom, for example, teachers as role models should not commit violence against students or set an example in front of students. Educators and education personnel must understand the rights that must be obtained by students, if educators do not understand educators must attend related trainings. The implementation of child-friendly learning processes both in the classroom and outdoors is mandatory in accordance with the rules and policies of child-friendly school programs. Student participation in learning will increase because students feel safe and comfortable when studying so that achievements will be highlighted by students.
STUDI KEMAMPUAN GURU KIMIA SMA LULUSAN UNY DALAM MENGEMBANGKAN SOAL UAS BERBASIS HOTS Iskandar, Dodi; Senam, Senam
Jurnal Inovasi Pendidikan IPA Vol. 1 No. 1: April 2015
Publisher : Faculty of Mathematics and Natural Sciences, Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (202.655 KB) | DOI: 10.21831/jipi.v1i1.4533

Abstract

This study aimed to investigate senior high school chemistry teachers ability to develop semester examination materials based on higher-order thinking skills. This kind of research was a survey. A number of respondents were 15 chemistry teachers with 559 questions of semester final examination in year 2013. The used methods was documentation. This research used a document check list as an instrument to collect data. The analyzed data were C1 (remember), C2 (understand), C3 (apply) that included lower order thinking skills (LOTS), C4 (analyze), C5 (evaluate) and C6 (create) which classified to higher order thingking skills (HOTS). The results of the study was senior high school chemistry teachers ability to develop a semester examination material based on higher order thinking skills is 13,9%, which consists of C4 13.2%; C5 0.7% and C6 0.0%.
Instructional Leadership of Principals in Building Effective Schools at Ratu Safiatuddin Cluster II Primary Schools: A Qualitative Analysis Assisted by NVivo Iskandar, Dodi; Jamaluddin, Jamaluddin; Rizki, Sari
Electronic Journal of Education, Social Economics and Technology Vol 6, No 2 (2025)
Publisher : SAINTIS Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33122/ejeset.v6i2.1321

Abstract

This study aims to describe the instructional leadership practices of principals in building effective schools at Sekolah Dasar Gugus II Ratu Safiatuddin, Aceh Tamiang Regency. The research uses a descriptive qualitative approach with data collection techniques through in-depth interviews, observation, and document study. Data analysis was conducted thematically with the assistance of NVivo software to ensure depth and transparency. The results reveal three main instructional leadership practices: (1) continuous and feedback-based academic supervision, (2) teacher professional development through training and collaboration in Teacher Working Groups (KKG), and (3) the creation of a positive school culture characterized by open communication, appreciation, and discipline. Triangulation analysis using NVivo's project map feature shows a strong alignment between the perspectives of principals and teachers, confirming that these practices tangibly shape a safe, comfortable, and conducive learning climate. The main obstacle faced is the high administrative burden, which limits time for instructional functions. The study concludes that structured and learning-oriented instructional leadership is a key factor in building primary school effectiveness and recommends the need for supportive policies to strengthen the instructional role of principals amid administrative challenges.